Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-74 |
Sentence |
denotes |
The influence of ovarian steroids on ovine endometrial glycosaminoglycans. |
TextSentencer_T2 |
75-194 |
Sentence |
denotes |
The ovine endometrium is subjected to cyclic oscillations of estrogen and progesterone in preparation for implantation. |
TextSentencer_T3 |
195-355 |
Sentence |
denotes |
One response to fluctuating hormonal levels is the degree of hydration of the tissue, suggesting cyclical alterations in glycosaminoglycan/proteoglycan content. |
TextSentencer_T4 |
356-513 |
Sentence |
denotes |
The aim of the present study was to quantitate and characterize glycosaminoglycans in the ovine endometrium during estrogen and progesterone dominant stages. |
TextSentencer_T5 |
514-796 |
Sentence |
denotes |
Endogenous endometrial glycosaminoglycan content was determined by chemical analysis and characterized by enzyme specific or chemical degradation. [(35)S]-sulphate and [(3)H]-glucosamine labeled proteoglycans/glycosaminoglycans were extracted by cell lysis or with 4M guanidine-HCl. |
TextSentencer_T6 |
797-888 |
Sentence |
denotes |
Extracts were purified by anion exchange and gel chromatography and characterized as above. |
TextSentencer_T7 |
889-1040 |
Sentence |
denotes |
Estrogen and progesterone dominant endometrium contained 3.2 +/- 0.1 and 2.1 +/- 0.1 mg endogenous glycosaminoglycan/g dehydrated tissue, respectively. |
TextSentencer_T8 |
1041-1155 |
Sentence |
denotes |
Characterization of endogenous glycosaminoglycan showed chondroitin sulphate and hyaluronan contributing over 80%. |
TextSentencer_T9 |
1156-1324 |
Sentence |
denotes |
The major difference between hormonal dominant tissue was a higher estrogenic hyaluronan percentage and a higher progestational keratan sulphate percentage (p < 0.001). |
TextSentencer_T10 |
1325-1439 |
Sentence |
denotes |
Estrogen dominant tissue incorporated 1.6-1.9 fold more radiolabeled proteoglycans/glycosaminoglycans (p < 0.001). |
TextSentencer_T11 |
1440-1562 |
Sentence |
denotes |
Analysis of newly synthesized proteoglycans/glycosaminoglycans revealed a heparan/chondroitin sulphate ratio of 1:2.2-2.5. |
TextSentencer_T12 |
1563-1597 |
Sentence |
denotes |
Keratan sulphate was not detected. |
TextSentencer_T13 |
1598-1666 |
Sentence |
denotes |
Estrogenic hyaluronan was 1.6 fold greater in [(3)H]-labeled tissue. |
TextSentencer_T14 |
1667-1861 |
Sentence |
denotes |
Analysis of labeled proteoglycans/glycosaminoglycans revealed two size classes with apparent molecular weights >2.0 x 10(6) and 0.8-1.1 x 10(5) and a charge class eluting between 0.1-0.5 M NaCl. |
TextSentencer_T15 |
1862-2094 |
Sentence |
denotes |
The greater glycosaminoglycan content (particularly hyaluronan) and synthesis in estrogen dominant tissue supports a role for steroid hormones in endometrial glycosaminoglycan/proteoglycan regulation and consequent tissue hydration. |
TextSentencer_T16 |
2095-2206 |
Sentence |
denotes |
It also suggests a role for these macromolecules in endometrial function and possibly the implantation process. |
T1 |
0-74 |
Sentence |
denotes |
The influence of ovarian steroids on ovine endometrial glycosaminoglycans. |
T2 |
75-194 |
Sentence |
denotes |
The ovine endometrium is subjected to cyclic oscillations of estrogen and progesterone in preparation for implantation. |
T3 |
195-355 |
Sentence |
denotes |
One response to fluctuating hormonal levels is the degree of hydration of the tissue, suggesting cyclical alterations in glycosaminoglycan/proteoglycan content. |
T4 |
356-513 |
Sentence |
denotes |
The aim of the present study was to quantitate and characterize glycosaminoglycans in the ovine endometrium during estrogen and progesterone dominant stages. |
T5 |
514-796 |
Sentence |
denotes |
Endogenous endometrial glycosaminoglycan content was determined by chemical analysis and characterized by enzyme specific or chemical degradation. [(35)S]-sulphate and [(3)H]-glucosamine labeled proteoglycans/glycosaminoglycans were extracted by cell lysis or with 4M guanidine-HCl. |
T6 |
797-888 |
Sentence |
denotes |
Extracts were purified by anion exchange and gel chromatography and characterized as above. |
T7 |
889-1040 |
Sentence |
denotes |
Estrogen and progesterone dominant endometrium contained 3.2 +/- 0.1 and 2.1 +/- 0.1 mg endogenous glycosaminoglycan/g dehydrated tissue, respectively. |
T8 |
1041-1155 |
Sentence |
denotes |
Characterization of endogenous glycosaminoglycan showed chondroitin sulphate and hyaluronan contributing over 80%. |
T9 |
1156-1324 |
Sentence |
denotes |
The major difference between hormonal dominant tissue was a higher estrogenic hyaluronan percentage and a higher progestational keratan sulphate percentage (p < 0.001). |
T10 |
1325-1439 |
Sentence |
denotes |
Estrogen dominant tissue incorporated 1.6-1.9 fold more radiolabeled proteoglycans/glycosaminoglycans (p < 0.001). |
T11 |
1440-1562 |
Sentence |
denotes |
Analysis of newly synthesized proteoglycans/glycosaminoglycans revealed a heparan/chondroitin sulphate ratio of 1:2.2-2.5. |
T12 |
1563-1597 |
Sentence |
denotes |
Keratan sulphate was not detected. |
T13 |
1598-1666 |
Sentence |
denotes |
Estrogenic hyaluronan was 1.6 fold greater in [(3)H]-labeled tissue. |
T14 |
1667-1861 |
Sentence |
denotes |
Analysis of labeled proteoglycans/glycosaminoglycans revealed two size classes with apparent molecular weights >2.0 x 10(6) and 0.8-1.1 x 10(5) and a charge class eluting between 0.1-0.5 M NaCl. |
T15 |
1862-2094 |
Sentence |
denotes |
The greater glycosaminoglycan content (particularly hyaluronan) and synthesis in estrogen dominant tissue supports a role for steroid hormones in endometrial glycosaminoglycan/proteoglycan regulation and consequent tissue hydration. |
T16 |
2095-2206 |
Sentence |
denotes |
It also suggests a role for these macromolecules in endometrial function and possibly the implantation process. |