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PubMed:14707484 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 1032-1051 Glycan_Motif denotes N-acetyllactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 1032-1051 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyllactosamine

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-57 Sentence denotes In vivo glycosylation of MUC1 in airway epithelial cells.
TextSentencer_T2 58-257 Sentence denotes The O-glycans that decorate mucin glycoproteins contribute to the biophysical and biochemical properties of these molecules and hence their function as a barrier and lubricant on epithelial surfaces.
TextSentencer_T3 258-343 Sentence denotes Alterations in mucin O-glycosylation in certain diseases may contribute to pathology.
TextSentencer_T4 344-494 Sentence denotes It is known that both the host cell type and the amino acid sequence of the mucin tandem repeat contribute to the O-glycosylation of a mucin molecule.
TextSentencer_T5 495-773 Sentence denotes We expressed an epitope-tagged MUC1 mucin cDNA construct in the airway cell line 16HBE14o- and the colon carcinoma cell line Caco2 and used Fast Atom Bombardment Mass Spectrometry to evaluate the contribution of the host cell to differences in O-glycosylation of a single mucin.
TextSentencer_T6 774-905 Sentence denotes Many of the glycans detected on the MUC1 mucin were common to both cell types, as would be predicted from biosynthetic constraints.
TextSentencer_T7 906-1115 Sentence denotes However, MUC1 synthesized in the airway cell line showed comparatively low levels of sialylation but carried a range of oligo-N-acetyllactosamine structures that were not seen in the colon carcinoma cell line.
T1 0-57 Sentence denotes In vivo glycosylation of MUC1 in airway epithelial cells.
T2 58-257 Sentence denotes The O-glycans that decorate mucin glycoproteins contribute to the biophysical and biochemical properties of these molecules and hence their function as a barrier and lubricant on epithelial surfaces.
T3 258-343 Sentence denotes Alterations in mucin O-glycosylation in certain diseases may contribute to pathology.
T4 344-494 Sentence denotes It is known that both the host cell type and the amino acid sequence of the mucin tandem repeat contribute to the O-glycosylation of a mucin molecule.
T5 495-773 Sentence denotes We expressed an epitope-tagged MUC1 mucin cDNA construct in the airway cell line 16HBE14o- and the colon carcinoma cell line Caco2 and used Fast Atom Bombardment Mass Spectrometry to evaluate the contribution of the host cell to differences in O-glycosylation of a single mucin.
T6 774-905 Sentence denotes Many of the glycans detected on the MUC1 mucin were common to both cell types, as would be predicted from biosynthetic constraints.
T7 906-1115 Sentence denotes However, MUC1 synthesized in the airway cell line showed comparatively low levels of sialylation but carried a range of oligo-N-acetyllactosamine structures that were not seen in the colon carcinoma cell line.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 594-599 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T2 1089-1094 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 594-609 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032
T2 1089-1104 Disease denotes colon carcinoma http://purl.obolibrary.org/obo/MONDO_0002032

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 594-599 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T2 1089-1094 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 33-56 Body_part denotes airway epithelial cells http://purl.obolibrary.org/obo/CL_0002368
T2 559-565 Body_part denotes airway http://purl.obolibrary.org/obo/UBERON_0000117|http://purl.obolibrary.org/obo/UBERON_0001005
T4 594-599 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T5 939-945 Body_part denotes airway http://purl.obolibrary.org/obo/UBERON_0000117|http://purl.obolibrary.org/obo/UBERON_0001005
T7 1089-1094 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 600-609 Phenotype denotes carcinoma HP:0030731
T2 1095-1104 Phenotype denotes carcinoma HP:0030731

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 33-56 Cell denotes airway epithelial cells http://purl.obolibrary.org/obo/CL:0002368