PubMed:14693916
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/14693916","sourcedb":"PubMed","sourceid":"14693916","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/14693916","text":"Biosynthesis of 6-deoxyhexose glycans in bacteria.\nAfter the breakthroughs in genomic sequencing, one of the next challenges remains to understand the molecular biology of other classes of biomolecules, such as protein and lipids, many of which carry specific glycomodification when mediating their biological functions. This review focuses on the 6-deoxyhexose biosynthesis of cell surface glycans of three Gram-negative pathogens, Helicobacter pylori, Pseudomonas aeruginosa, and Actinobacillus actinomycetemcomitans serotype a. 6-Deoxysugars are important functional components of cell surface glycans, and their biosynthetic pathways might be suitable targets for novel interventions of antibacterial chemotherapy.","tracks":[{"project":"GlycoBiology-PACDB","denotations":[{"id":"_T1","span":{"begin":433,"end":452},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC049,LEC063,LEC070,LEC078,LEC107,LEC336,LEC343,LEC409,LEC419,LEC446,LEC582"},{"id":"_T2","span":{"begin":433,"end":452},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC362"},{"id":"_T3","span":{"begin":433,"end":452},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC121"},{"id":"_T4","span":{"begin":433,"end":452},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC444"},{"id":"_T5","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC584"},{"id":"_T6","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC001,LEC005,LEC007,LEC029,LEC030,LEC032,LEC135,LEC191,LEC229,LEC231,LEC368,LEC447,LEC617,LEC676,PGG008"},{"id":"_T7","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC709"},{"id":"_T8","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC325"},{"id":"_T9","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC466"},{"id":"_T10","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC703"},{"id":"_T11","span":{"begin":454,"end":476},"obj":"http://acgg.asia/db/diseases/pacdb/lec?ids=LEC721"}],"attributes":[{"subj":"_T1","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T2","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T3","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T4","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T5","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T6","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T7","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T8","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T9","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T10","pred":"source","obj":"GlycoBiology-PACDB"},{"subj":"_T11","pred":"source","obj":"GlycoBiology-PACDB"}]},{"project":"GlycoBiology-FMA","denotations":[{"id":"_T1","span":{"begin":78,"end":85},"obj":"FMAID:198062"},{"id":"_T2","span":{"begin":78,"end":85},"obj":"FMAID:84116"},{"id":"_T3","span":{"begin":211,"end":218},"obj":"FMAID:67257"},{"id":"_T4","span":{"begin":211,"end":218},"obj":"FMAID:165447"},{"id":"_T5","span":{"begin":223,"end":229},"obj":"FMAID:67264"},{"id":"_T6","span":{"begin":223,"end":229},"obj":"FMAID:165448"},{"id":"_T7","span":{"begin":378,"end":390},"obj":"FMAID:212684"},{"id":"_T8","span":{"begin":378,"end":390},"obj":"FMAID:200942"},{"id":"_T9","span":{"begin":383,"end":390},"obj":"FMAID:146300"},{"id":"_T10","span":{"begin":383,"end":390},"obj":"FMAID:50594"},{"id":"_T11","span":{"begin":584,"end":596},"obj":"FMAID:200942"},{"id":"_T12","span":{"begin":584,"end":596},"obj":"FMAID:212684"},{"id":"_T13","span":{"begin":589,"end":596},"obj":"FMAID:146300"},{"id":"_T14","span":{"begin":589,"end":596},"obj":"FMAID:50594"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"attributes":[{"subj":"_T1","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T2","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T3","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T4","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T5","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T6","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T7","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T8","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T9","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T10","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T11","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T12","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T13","pred":"source","obj":"GlycoBiology-FMA"},{"subj":"_T14","pred":"source","obj":"GlycoBiology-FMA"}]},{"project":"GlycoBiology-NCBITAXON","denotations":[{"id":"T1","span":{"begin":41,"end":49},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/2"},{"id":"T2","span":{"begin":41,"end":49},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/629395"},{"id":"T3","span":{"begin":231,"end":235},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/9973"},{"id":"T4","span":{"begin":299,"end":319},"obj":"http://purl.bioontology.org/ontology/STY/T039"},{"id":"T5","span":{"begin":433,"end":445},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/209"},{"id":"T6","span":{"begin":454,"end":465},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/651740"},{"id":"T7","span":{"begin":454,"end":465},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/135621"},{"id":"T8","span":{"begin":454,"end":476},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/287"},{"id":"T9","span":{"begin":482,"end":496},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/713"},{"id":"T10","span":{"begin":482,"end":496},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/716"},{"id":"T11","span":{"begin":482,"end":518},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/714"}],"attributes":[{"subj":"T1","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T2","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T3","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T4","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T5","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T6","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T7","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T8","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T9","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T10","pred":"source","obj":"GlycoBiology-NCBITAXON"},{"subj":"T11","pred":"source","obj":"GlycoBiology-NCBITAXON"}]},{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":50},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":51,"end":320},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":321,"end":530},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":531,"end":718},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":50},"obj":"Sentence"},{"id":"T2","span":{"begin":51,"end":320},"obj":"Sentence"},{"id":"T3","span":{"begin":321,"end":530},"obj":"Sentence"},{"id":"T4","span":{"begin":531,"end":718},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":50},"obj":"Sentence"},{"id":"T2","span":{"begin":51,"end":320},"obj":"Sentence"},{"id":"T3","span":{"begin":321,"end":530},"obj":"Sentence"},{"id":"T4","span":{"begin":531,"end":718},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T3","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T4","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"}]},{"project":"GO-BP","denotations":[{"id":"T1","span":{"begin":0,"end":12},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T2","span":{"begin":362,"end":374},"obj":"http://purl.obolibrary.org/obo/GO_0009058"},{"id":"T3","span":{"begin":211,"end":229},"obj":"http://purl.obolibrary.org/obo/GO_0006497"}],"attributes":[{"subj":"T1","pred":"source","obj":"GO-BP"},{"subj":"T2","pred":"source","obj":"GO-BP"},{"subj":"T3","pred":"source","obj":"GO-BP"}]},{"project":"GO-CC","denotations":[{"id":"T1","span":{"begin":378,"end":382},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T2","span":{"begin":584,"end":588},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T3","span":{"begin":378,"end":390},"obj":"http://purl.obolibrary.org/obo/GO_0009986"},{"id":"T4","span":{"begin":584,"end":596},"obj":"http://purl.obolibrary.org/obo/GO_0009986"}],"attributes":[{"subj":"T1","pred":"source","obj":"GO-CC"},{"subj":"T2","pred":"source","obj":"GO-CC"},{"subj":"T3","pred":"source","obj":"GO-CC"},{"subj":"T4","pred":"source","obj":"GO-CC"}]},{"project":"EDAM-topics","denotations":[{"id":"T1","span":{"begin":78,"end":85},"obj":"http://edamontology.org/topic_0622"},{"id":"T2","span":{"begin":86,"end":96},"obj":"http://edamontology.org/topic_3168"},{"id":"T3","span":{"begin":86,"end":96},"obj":"http://edamontology.org/topic_0080"},{"id":"T4","span":{"begin":151,"end":168},"obj":"http://edamontology.org/topic_3047"},{"id":"T5","span":{"begin":161,"end":168},"obj":"http://edamontology.org/topic_3070"},{"id":"T6","span":{"begin":211,"end":218},"obj":"http://edamontology.org/topic_0078"},{"id":"T7","span":{"begin":223,"end":229},"obj":"http://edamontology.org/topic_0153"},{"id":"T8","span":{"begin":422,"end":431},"obj":"http://edamontology.org/topic_0783"},{"id":"T9","span":{"begin":629,"end":637},"obj":"http://edamontology.org/topic_0602"},{"id":"T10","span":{"begin":656,"end":663},"obj":"http://edamontology.org/topic_0154"}],"attributes":[{"subj":"T1","pred":"source","obj":"EDAM-topics"},{"subj":"T2","pred":"source","obj":"EDAM-topics"},{"subj":"T3","pred":"source","obj":"EDAM-topics"},{"subj":"T4","pred":"source","obj":"EDAM-topics"},{"subj":"T5","pred":"source","obj":"EDAM-topics"},{"subj":"T6","pred":"source","obj":"EDAM-topics"},{"subj":"T7","pred":"source","obj":"EDAM-topics"},{"subj":"T8","pred":"source","obj":"EDAM-topics"},{"subj":"T9","pred":"source","obj":"EDAM-topics"},{"subj":"T10","pred":"source","obj":"EDAM-topics"}]},{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":41,"end":49},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":433,"end":452},"obj":"OrganismTaxon"},{"id":"T4","span":{"begin":454,"end":476},"obj":"OrganismTaxon"},{"id":"T5","span":{"begin":482,"end":518},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"2"},{"id":"A2","pred":"db_id","subj":"T1","obj":"629395"},{"id":"A3","pred":"db_id","subj":"T3","obj":"210"},{"id":"A4","pred":"db_id","subj":"T4","obj":"287"},{"id":"A5","pred":"db_id","subj":"T5","obj":"714"},{"subj":"T1","pred":"source","obj":"NCBITAXON"},{"subj":"T3","pred":"source","obj":"NCBITAXON"},{"subj":"T4","pred":"source","obj":"NCBITAXON"},{"subj":"T5","pred":"source","obj":"NCBITAXON"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"GlycoBiology-PACDB","color":"#c1ec93","default":true},{"id":"GlycoBiology-FMA","color":"#ec93db"},{"id":"GlycoBiology-NCBITAXON","color":"#93ece3"},{"id":"sentences","color":"#ecc993"},{"id":"GO-BP","color":"#af93ec"},{"id":"GO-CC","color":"#93ec95"},{"id":"EDAM-topics","color":"#ec93ab"},{"id":"NCBITAXON","color":"#93c5ec"}]}]}}