PubMed:14555521 / 0-563 JSONTXT

{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":169,"end":176},"obj":"HP_0002664"},{"id":"T2","span":{"begin":477,"end":484},"obj":"HP_0002664"},{"id":"T3","span":{"begin":526,"end":532},"obj":"HP_0002664"}],"text":"Estrogen receptor-beta expression in human testicular germ cell tumors.\nPURPOSE: Estrogen exposure has been linked to a risk for the development of testicular germ cell cancers. The effects of estrogen are now known to be mediated by estrogen receptor (ER)-alpha and -beta receptor subtypes, but only ER-beta has been found in human normal testis. The goal of the present study was to compare the localization and expression levels of these ER subtypes in testicular germ cell cancers (seminomas and nonseminomatous germ cell tumors) with normal testis. For compl"}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"14555521-3#93#95#gene2099","span":{"begin":441,"end":443},"obj":"gene2099"},{"id":"14555521-3#119#136#diseaseC0740345","span":{"begin":467,"end":484},"obj":"diseaseC0740345"},{"id":"14555521-3#138#147#diseaseC0036631","span":{"begin":486,"end":495},"obj":"diseaseC0036631"},{"id":"14555521-3#152#184#diseaseC1266158","span":{"begin":500,"end":532},"obj":"diseaseC1266158"}],"relations":[{"id":"93#95#gene2099119#136#diseaseC0740345","pred":"associated_with","subj":"14555521-3#93#95#gene2099","obj":"14555521-3#119#136#diseaseC0740345"},{"id":"93#95#gene2099138#147#diseaseC0036631","pred":"associated_with","subj":"14555521-3#93#95#gene2099","obj":"14555521-3#138#147#diseaseC0036631"},{"id":"93#95#gene2099152#184#diseaseC1266158","pred":"associated_with","subj":"14555521-3#93#95#gene2099","obj":"14555521-3#152#184#diseaseC1266158"}],"text":"Estrogen receptor-beta expression in human testicular germ cell tumors.\nPURPOSE: Estrogen exposure has been linked to a risk for the development of testicular germ cell cancers. The effects of estrogen are now known to be mediated by estrogen receptor (ER)-alpha and -beta receptor subtypes, but only ER-beta has been found in human normal testis. The goal of the present study was to compare the localization and expression levels of these ER subtypes in testicular germ cell cancers (seminomas and nonseminomatous germ cell tumors) with normal testis. For compl"}