PubMed:14514712
Annnotations
Glycan-Motif
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 252-263 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 252-263 | Glycan_Motif | denotes | sialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81533KY |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 252-263 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 117-122 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T2 | 320-325 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T3 | 413-418 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T4 | 547-552 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T5 | 851-855 | http://purl.obolibrary.org/obo/MAT_0000029 | denotes | male |
| T6 | 1630-1635 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 357-364 | HP_0002664 | denotes | cancers |
| T2 | 581-590 | HP_0001394 | denotes | cirrhosis |
| T3 | 829-838 | HP_0001394 | denotes | cirrhosis |
| T4 | 1501-1510 | HP_0001394 | denotes | cirrhosis |
| T5 | 1571-1580 | HP_0001394 | denotes | cirrhosis |
ICD10
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 413-427 | http://purl.bioontology.org/ontology/ICD10/K70-K77.9 | denotes | liver diseases |
| T2 | 413-427 | http://purl.bioontology.org/ontology/ICD10/K76.9 | denotes | liver diseases |
GlycoBiology-FMA
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| _T1 | 85-100 | FMAID:82782 | denotes | glycoconjugates |
| _T2 | 85-100 | FMAID:196776 | denotes | glycoconjugates |
| _T3 | 117-122 | FMAID:7197 | denotes | liver |
| _T4 | 117-122 | FMAID:93672 | denotes | liver |
| _T5 | 267-280 | FMAID:62925 | denotes | glycoproteins |
| _T6 | 267-280 | FMAID:167256 | denotes | glycoproteins |
| _T7 | 320-325 | FMAID:7197 | denotes | liver |
| _T8 | 320-325 | FMAID:93672 | denotes | liver |
| _T9 | 413-418 | FMAID:93672 | denotes | liver |
| _T10 | 413-418 | FMAID:7197 | denotes | liver |
| _T11 | 518-529 | FMAID:82792 | denotes | lactosamine |
| _T12 | 518-529 | FMAID:196787 | denotes | lactosamine |
| _T13 | 547-552 | FMAID:93672 | denotes | liver |
| _T14 | 547-552 | FMAID:7197 | denotes | liver |
| _T15 | 965-980 | FMAID:196776 | denotes | glycoconjugates |
| _T16 | 965-980 | FMAID:82782 | denotes | glycoconjugates |
| _T17 | 988-994 | FMAID:256050 | denotes | tissue |
| _T18 | 1181-1185 | FMAID:198663 | denotes | gene |
| _T19 | 1426-1431 | FMAID:68646 | denotes | cells |
| _T20 | 1426-1431 | FMAID:169002 | denotes | cells |
| _T21 | 1630-1635 | FMAID:93672 | denotes | liver |
| _T22 | 1630-1635 | FMAID:7197 | denotes | liver |
| _T23 | 1636-1649 | FMAID:62925 | denotes | glycoproteins |
| _T24 | 1636-1649 | FMAID:167256 | denotes | glycoproteins |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 792-798 | http://www.uniprot.org/uniprot/P82912 | denotes | 2, HCC |
| T2 | 792-798 | http://www.uniprot.org/uniprot/Q16663 | denotes | 2, HCC |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 14-18 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T2 | 14-18 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T3 | 156-160 | http://purl.bioontology.org/ontology/NCBITAXON/3554 | denotes | beta |
| T4 | 156-160 | http://purl.bioontology.org/ontology/NCBITAXON/158455 | denotes | beta |
| T5 | 357-364 | http://purl.bioontology.org/ontology/NCBITAXON/6754 | denotes | cancers |
| T6 | 723-729 | http://purl.bioontology.org/ontology/STY/T096 | denotes | groups |
| T7 | 882-896 | http://purl.bioontology.org/ontology/NCBITAXON/4202 | denotes | Sambucus nigra |
| T8 | 988-994 | http://purl.bioontology.org/ontology/STY/T024 | denotes | tissue |
| T9 | 1385-1398 | http://purl.bioontology.org/ontology/NCBITAXON/691256 | denotes | heterogeneous |
| T10 | 1385-1398 | http://purl.bioontology.org/ontology/NCBITAXON/1113441 | denotes | heterogeneous |
| T11 | 1426-1431 | http://purl.bioontology.org/ontology/STY/T025 | denotes | cells |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-155 | Sentence | denotes | Expression of beta-galactoside alpha2,6 sialyltransferase and of alpha2,6-sialylated glycoconjugates in normal human liver, hepatocarcinoma, and cirrhosis. |
| TextSentencer_T2 | 156-281 | Sentence | denotes | beta-Galactoside alpha2,6-sialyltransferase (ST6Gal.I) mediates the addition of alpha2,6-linked sialic acid to glycoproteins. |
| TextSentencer_T3 | 282-428 | Sentence | denotes | ST6Gal.I is strongly expressed by the liver and is up-regulated in several cancers, but little is known of its regulation in human liver diseases. |
| TextSentencer_T4 | 429-591 | Sentence | denotes | We have investigated the expression of ST6Gal.I and its product, the alpha2,6-sialylated lactosamine, in normal human liver, hepatocarcinoma (HCC), and cirrhosis. |
| TextSentencer_T5 | 592-699 | Sentence | denotes | We found that both ST6Gal.I activity and mRNA can undergo up- or down-regulation in different HCC patients. |
| TextSentencer_T6 | 700-865 | Sentence | denotes | At the mRNA level, the groups of specimens showing the highest expression were HCC of grade 2, HCC developed without preexisting cirrhosis, and HCC of male patients. |
| TextSentencer_T7 | 866-1159 | Sentence | denotes | The lectin from Sambucus nigra (SNA) reveals a significative overexpression of alpha2,6-sialylated glycoconjugates in HCC tissue homogenates and their intracellular accumulation in HCC histological sections, even though in a few cases the extent of alpha2,6-sialylation dramatically decreases. |
| TextSentencer_T8 | 1160-1290 | Sentence | denotes | Transcription of the gene occurs through at least two different promoters, resulting in two differentially expressed mRNA species. |
| TextSentencer_T9 | 1291-1432 | Sentence | denotes | RNA in situ hybridization reveals that the ST6Gal.I mRNA can be expressed at a quantitatively heterogeneous level among the neoplastic cells. |
| TextSentencer_T10 | 1433-1511 | Sentence | denotes | Neither ST6Gal.I expression nor alpha2,6-sialylation are altered in cirrhosis. |
| TextSentencer_T11 | 1512-1650 | Sentence | denotes | These data indicate that neoplastic transformation but not cirrhosis can alter the process of alpha2,6-sialylation of liver glycoproteins. |
| T1 | 0-155 | Sentence | denotes | Expression of beta-galactoside alpha2,6 sialyltransferase and of alpha2,6-sialylated glycoconjugates in normal human liver, hepatocarcinoma, and cirrhosis. |
| T2 | 156-281 | Sentence | denotes | beta-Galactoside alpha2,6-sialyltransferase (ST6Gal.I) mediates the addition of alpha2,6-linked sialic acid to glycoproteins. |
| T3 | 282-428 | Sentence | denotes | ST6Gal.I is strongly expressed by the liver and is up-regulated in several cancers, but little is known of its regulation in human liver diseases. |
| T4 | 429-591 | Sentence | denotes | We have investigated the expression of ST6Gal.I and its product, the alpha2,6-sialylated lactosamine, in normal human liver, hepatocarcinoma (HCC), and cirrhosis. |
| T5 | 592-699 | Sentence | denotes | We found that both ST6Gal.I activity and mRNA can undergo up- or down-regulation in different HCC patients. |
| T6 | 700-865 | Sentence | denotes | At the mRNA level, the groups of specimens showing the highest expression were HCC of grade 2, HCC developed without preexisting cirrhosis, and HCC of male patients. |
| T7 | 866-1159 | Sentence | denotes | The lectin from Sambucus nigra (SNA) reveals a significative overexpression of alpha2,6-sialylated glycoconjugates in HCC tissue homogenates and their intracellular accumulation in HCC histological sections, even though in a few cases the extent of alpha2,6-sialylation dramatically decreases. |
| T8 | 1160-1290 | Sentence | denotes | Transcription of the gene occurs through at least two different promoters, resulting in two differentially expressed mRNA species. |
| T9 | 1291-1432 | Sentence | denotes | RNA in situ hybridization reveals that the ST6Gal.I mRNA can be expressed at a quantitatively heterogeneous level among the neoplastic cells. |
| T10 | 1433-1511 | Sentence | denotes | Neither ST6Gal.I expression nor alpha2,6-sialylation are altered in cirrhosis. |
| T11 | 1512-1650 | Sentence | denotes | These data indicate that neoplastic transformation but not cirrhosis can alter the process of alpha2,6-sialylation of liver glycoproteins. |
| T1 | 0-155 | Sentence | denotes | Expression of beta-galactoside alpha2,6 sialyltransferase and of alpha2,6-sialylated glycoconjugates in normal human liver, hepatocarcinoma, and cirrhosis. |
| T2 | 156-281 | Sentence | denotes | beta-Galactoside alpha2,6-sialyltransferase (ST6Gal.I) mediates the addition of alpha2,6-linked sialic acid to glycoproteins. |
| T3 | 282-428 | Sentence | denotes | ST6Gal.I is strongly expressed by the liver and is up-regulated in several cancers, but little is known of its regulation in human liver diseases. |
| T4 | 429-591 | Sentence | denotes | We have investigated the expression of ST6Gal.I and its product, the alpha2,6-sialylated lactosamine, in normal human liver, hepatocarcinoma (HCC), and cirrhosis. |
| T5 | 592-699 | Sentence | denotes | We found that both ST6Gal.I activity and mRNA can undergo up- or down-regulation in different HCC patients. |
| T6 | 700-865 | Sentence | denotes | At the mRNA level, the groups of specimens showing the highest expression were HCC of grade 2, HCC developed without preexisting cirrhosis, and HCC of male patients. |
| T7 | 866-1159 | Sentence | denotes | The lectin from Sambucus nigra (SNA) reveals a significative overexpression of alpha2,6-sialylated glycoconjugates in HCC tissue homogenates and their intracellular accumulation in HCC histological sections, even though in a few cases the extent of alpha2,6-sialylation dramatically decreases. |
| T8 | 1160-1290 | Sentence | denotes | Transcription of the gene occurs through at least two different promoters, resulting in two differentially expressed mRNA species. |
| T9 | 1291-1432 | Sentence | denotes | RNA in situ hybridization reveals that the ST6Gal.I mRNA can be expressed at a quantitatively heterogeneous level among the neoplastic cells. |
| T10 | 1433-1511 | Sentence | denotes | Neither ST6Gal.I expression nor alpha2,6-sialylation are altered in cirrhosis. |
| T11 | 1512-1650 | Sentence | denotes | These data indicate that neoplastic transformation but not cirrhosis can alter the process of alpha2,6-sialylation of liver glycoproteins. |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 74-84 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
| T2 | 507-517 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
| T3 | 954-964 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylated |
| T4 | 1124-1135 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylation |
| T5 | 1474-1485 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylation |
| T6 | 1615-1626 | http://purl.obolibrary.org/obo/GO_0097503 | denotes | sialylation |
| T7 | 336-345 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulated |
| T8 | 393-403 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T9 | 662-672 | http://purl.obolibrary.org/obo/GO_0065007 | denotes | regulation |
| T10 | 799-808 | http://purl.obolibrary.org/obo/GO_0032502 | denotes | developed |
| T11 | 1160-1173 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | Transcription |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1017-1030 | http://purl.obolibrary.org/obo/GO_0005622 | denotes | intracellular |
| T2 | 1426-1431 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T3 | 1461-1464 | http://purl.obolibrary.org/obo/GO_0005731 | denotes | nor |
UBERON-AE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 117-122 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T2 | 320-325 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T3 | 413-418 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T4 | 547-552 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T5 | 1630-1635 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| T6 | 988-994 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 111-116 | http://edamontology.org/topic_2815 | denotes | human |
| T2 | 357-364 | http://edamontology.org/topic_2640 | denotes | cancers |
| T3 | 407-412 | http://edamontology.org/topic_2815 | denotes | human |
| T4 | 407-427 | http://edamontology.org/topic_0803 | denotes | human liver diseases |
| T5 | 419-427 | http://edamontology.org/topic_0634 | denotes | diseases |
| T6 | 541-546 | http://edamontology.org/topic_2815 | denotes | human |
| T7 | 1160-1173 | http://edamontology.org/topic_0110 | denotes | Transcription |
| T8 | 1160-1173 | http://edamontology.org/topic_3308 | denotes | Transcription |
| T9 | 1160-1173 | http://edamontology.org/topic_0203 | denotes | Transcription |
| T10 | 1160-1173 | http://edamontology.org/topic_3512 | denotes | Transcription |
| T11 | 1224-1233 | http://edamontology.org/topic_0111 | denotes | promoters |
| T12 | 1224-1233 | http://edamontology.org/topic_0749 | denotes | promoters |
| T13 | 1224-1233 | http://edamontology.org/topic_1312 | denotes | promoters |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 104-110 | http://edamontology.org/operation_3435 | denotes | normal |
| T2 | 534-540 | http://edamontology.org/operation_3435 | denotes | normal |
| T3 | 1252-1276 | http://edamontology.org/operation_3742 | denotes | differentially expressed |
| T4 | 1370-1384 | http://edamontology.org/data_1426 | denotes | quantitatively |
| T5 | 1370-1384 | http://edamontology.org/operation_3630 | denotes | quantitatively |
| T6 | 1518-1522 | http://edamontology.org/data_0006 | denotes | data |
| T7 | 1595-1602 | http://edamontology.org/operation_2409 | denotes | process |
| T8 | 1595-1602 | http://edamontology.org/operation_0004 | denotes | process |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 14514712-2#0#8#gene6480 | 282-290 | gene6480 | denotes | ST6Gal.I |
| 14514712-2#131#145#diseaseC0023895 | 413-427 | diseaseC0023895 | denotes | liver diseases |
| 14514712-3#39#47#gene6480 | 468-476 | gene6480 | denotes | ST6Gal.I |
| 14514712-3#125#140#diseaseC2239176 | 554-569 | diseaseC2239176 | denotes | hepatocarcinoma |
| 14514712-3#142#145#diseaseC2239176 | 571-574 | diseaseC2239176 | denotes | HCC |
| 14514712-9#8#16#gene6480 | 1441-1449 | gene6480 | denotes | ST6Gal.I |
| 14514712-9#68#77#diseaseC0023890 | 1501-1510 | diseaseC0023890 | denotes | cirrhosis |
| 14514712-9#68#77#diseaseC1623038 | 1501-1510 | diseaseC1623038 | denotes | cirrhosis |
| 0#8#gene6480131#145#diseaseC0023895 | 14514712-2#0#8#gene6480 | 14514712-2#131#145#diseaseC0023895 | associated_with | ST6Gal.I,liver diseases |
| 39#47#gene6480125#140#diseaseC2239176 | 14514712-3#39#47#gene6480 | 14514712-3#125#140#diseaseC2239176 | associated_with | ST6Gal.I,hepatocarcinoma |
| 39#47#gene6480142#145#diseaseC2239176 | 14514712-3#39#47#gene6480 | 14514712-3#142#145#diseaseC2239176 | associated_with | ST6Gal.I,HCC |
| 8#16#gene648068#77#diseaseC0023890 | 14514712-9#8#16#gene6480 | 14514712-9#68#77#diseaseC0023890 | associated_with | ST6Gal.I,cirrhosis |
| 8#16#gene648068#77#diseaseC1623038 | 14514712-9#8#16#gene6480 | 14514712-9#68#77#diseaseC1623038 | associated_with | ST6Gal.I,cirrhosis |
GlycoBiology-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 117-122 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T2 | 320-325 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T3 | 413-418 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T4 | 547-552 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
| T5 | 851-855 | http://purl.obolibrary.org/obo/MAT_0000029 | denotes | male |
| T6 | 1630-1635 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
GlycoBiology-Motifs
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 518-529 | http://rdf.glycoinfo.org/glycan/G00055MO | denotes | lactosamine |
performance-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-UBERON-AE-B_T1 | 988-994 | http://purl.obolibrary.org/obo/UBERON_0000479 | denotes | tissue |
| PD-UBERON-AE-B_T2 | 117-122 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| PD-UBERON-AE-B_T3 | 320-325 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| PD-UBERON-AE-B_T4 | 413-418 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| PD-UBERON-AE-B_T5 | 547-552 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
| PD-UBERON-AE-B_T6 | 1630-1635 | http://purl.obolibrary.org/obo/UBERON_0002107 | denotes | liver |
Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| Lectin_T1 | 898-901 | https://acgg.asia/db/lfdb/LfDB0233 | denotes | SNA |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 282-290 | gene:6480 | denotes | ST6Gal.I |
| T1 | 357-364 | disease:C0006826 | denotes | cancers |
| T2 | 282-290 | gene:6480 | denotes | ST6Gal.I |
| T3 | 413-427 | disease:C0023895 | denotes | liver diseases |
| T4 | 468-476 | gene:6480 | denotes | ST6Gal.I |
| T5 | 554-569 | disease:C2239176 | denotes | hepatocarcinoma |
| T6 | 468-476 | gene:6480 | denotes | ST6Gal.I |
| T7 | 571-574 | disease:C2239176 | denotes | HCC |
| T8 | 468-476 | gene:6480 | denotes | ST6Gal.I |
| T9 | 581-590 | disease:C1623038 | denotes | cirrhosis |
| T10 | 468-476 | gene:6480 | denotes | ST6Gal.I |
| T11 | 581-590 | disease:C0023890 | denotes | cirrhosis |
| T12 | 1441-1449 | gene:6480 | denotes | ST6Gal.I |
| T13 | 1501-1510 | disease:C0023890 | denotes | cirrhosis |
| T14 | 1441-1449 | gene:6480 | denotes | ST6Gal.I |
| T15 | 1501-1510 | disease:C1623038 | denotes | cirrhosis |
| R1 | T0 | T1 | associated_with | ST6Gal.I,cancers |
| R2 | T2 | T3 | associated_with | ST6Gal.I,liver diseases |
| R3 | T4 | T5 | associated_with | ST6Gal.I,hepatocarcinoma |
| R4 | T6 | T7 | associated_with | ST6Gal.I,HCC |
| R5 | T8 | T9 | associated_with | ST6Gal.I,cirrhosis |
| R6 | T10 | T11 | associated_with | ST6Gal.I,cirrhosis |
| R7 | T12 | T13 | associated_with | ST6Gal.I,cirrhosis |
| R8 | T14 | T15 | associated_with | ST6Gal.I,cirrhosis |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 117-122 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T2 | 320-325 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T3 | 413-418 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T4 | 547-552 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
| T5 | 851-855 | Body_part | denotes | male | http://purl.obolibrary.org/obo/MAT_0000029 |
| T6 | 1630-1635 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 145-154 | Phenotype | denotes | cirrhosis | HP:0001394 |
| T2 | 413-427 | Phenotype | denotes | liver diseases | HP:0001392 |
| T3 | 581-590 | Phenotype | denotes | cirrhosis | HP:0001394 |
| T4 | 829-838 | Phenotype | denotes | cirrhosis | HP:0001394 |
| T5 | 1501-1510 | Phenotype | denotes | cirrhosis | HP:0001394 |
| T6 | 1571-1580 | Phenotype | denotes | cirrhosis | HP:0001394 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 145-154 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
| T2 | 413-427 | Disease | denotes | liver diseases | http://purl.obolibrary.org/obo/MONDO_0005154 |
| T3 | 571-574 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T4 | 581-590 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
| T5 | 686-689 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T6 | 779-782 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T7 | 795-798 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T8 | 829-838 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
| T9 | 844-847 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T10 | 984-987 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T11 | 1047-1050 | Disease | denotes | HCC | http://purl.obolibrary.org/obo/MONDO_0007256 |
| T12 | 1501-1510 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
| T13 | 1571-1580 | Disease | denotes | cirrhosis | http://purl.obolibrary.org/obo/MONDO_0005155 |
Lectin-Jamboree
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 870-876 | lectin | denotes | lectin |
Lectin-Jamboree-small
| Id | Subject | Object | Predicate | Lexical cue | glycosmos_id |
|---|---|---|---|---|---|
| T1 | 898-901 | Lectin | denotes | SNA | GL_003701 |
Lectin-Jamboree-Sentence
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-155 | Sentence | denotes | Expression of beta-galactoside alpha2,6 sialyltransferase and of alpha2,6-sialylated glycoconjugates in normal human liver, hepatocarcinoma, and cirrhosis. |
| T2 | 156-281 | Sentence | denotes | beta-Galactoside alpha2,6-sialyltransferase (ST6Gal.I) mediates the addition of alpha2,6-linked sialic acid to glycoproteins. |
| T3 | 282-428 | Sentence | denotes | ST6Gal.I is strongly expressed by the liver and is up-regulated in several cancers, but little is known of its regulation in human liver diseases. |
| T4 | 429-591 | Sentence | denotes | We have investigated the expression of ST6Gal.I and its product, the alpha2,6-sialylated lactosamine, in normal human liver, hepatocarcinoma (HCC), and cirrhosis. |
| T5 | 592-699 | Sentence | denotes | We found that both ST6Gal.I activity and mRNA can undergo up- or down-regulation in different HCC patients. |
| T6 | 700-865 | Sentence | denotes | At the mRNA level, the groups of specimens showing the highest expression were HCC of grade 2, HCC developed without preexisting cirrhosis, and HCC of male patients. |
| T7 | 866-1159 | Sentence | denotes | The lectin from Sambucus nigra (SNA) reveals a significative overexpression of alpha2,6-sialylated glycoconjugates in HCC tissue homogenates and their intracellular accumulation in HCC histological sections, even though in a few cases the extent of alpha2,6-sialylation dramatically decreases. |
| T8 | 1160-1290 | Sentence | denotes | Transcription of the gene occurs through at least two different promoters, resulting in two differentially expressed mRNA species. |
| T9 | 1291-1432 | Sentence | denotes | RNA in situ hybridization reveals that the ST6Gal.I mRNA can be expressed at a quantitatively heterogeneous level among the neoplastic cells. |
| T10 | 1433-1511 | Sentence | denotes | Neither ST6Gal.I expression nor alpha2,6-sialylation are altered in cirrhosis. |
| T11 | 1512-1650 | Sentence | denotes | These data indicate that neoplastic transformation but not cirrhosis can alter the process of alpha2,6-sialylation of liver glycoproteins. |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 111-116 | OrganismTaxon | denotes | human | 9606 |
| T2 | 407-412 | OrganismTaxon | denotes | human | 9606 |
| T3 | 541-546 | OrganismTaxon | denotes | human | 9606 |
| T4 | 882-896 | OrganismTaxon | denotes | Sambucus nigra | 4202 |
| T5 | 898-901 | OrganismTaxon | denotes | SNA | 4202 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 117-122 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T2 | 320-325 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T3 | 413-418 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T4 | 547-552 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T5 | 988-994 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
| T6 | 1017-1030 | Body_part | denotes | intracellular | http://purl.obolibrary.org/obo/GO_0005622 |
| T7 | 1630-1635 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 1415-1431 | Cell | denotes | neoplastic cells | http://purl.obolibrary.org/obo/CL:0001063 |