PubMed:1431113 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/1431113","sourcedb":"PubMed","sourceid":"1431113","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/1431113","text":"Redox status of cells influences constitutive or induced NF-kappa B translocation and HIV long terminal repeat activity in human T and monocytic cell lines.\nWe have tested the hypothesis that cellular activation events occurring in T lymphocytes and monocytes and mediated through translocation of the transcription factor NF-kappa B are dependent upon the constitutive redox status of these cells. We used phenolic, lipid-soluble, chain-breaking antioxidants (butylated hydroxyanisole (BHA), nordihydroquairetic acid, or alpha-tocopherol (vitamin E) to show that peroxyl radical scavenging in unstimulated and PMA- or TNF-stimulated cells blocks the functions depending on NF-kappa B activation. BHA was found to suppress not only PMA- or TNF-induced, but also constitutive, HIV-enhancer activity concomitant to an inhibition of NF-kappa B binding activity in both lymphoblastoid T (J.Jhan) and monocytic (U937) cell lines. This was also true for KBF (p50 homodimer) binding activity in U937 cells. Secretion of TNF, the product of another NF-kappa B-dependent gene, was abolished by BHA in PMA-stimulated U937 cells. The anti-oxidative effect of BHA was accompanied by an increase in thiol, but not glutathione, content in stimulated and unstimulated T cell, whereas TNF stimulation itself barely modified the cellular thiol level. Oxidative stress obtained by the addition of H2O2 to the culture medium of J.Jhan or U937 cells could not by itself induce NF-kappa B activation. These observations suggest that TNF and PMA do not lead to NF-kappa B activation through induction of changes in the cell redox status. Rather, TNF and PMA can exert their effect only if cells are in an appropriate redox status, because prior modification toward reduction with BHA treatment prevents this activation. It appears that a basal redox equilibrium tending toward oxidation is a prerequisite for full activation of transduction pathways regulating the activity of NF-kappa B-dependent genes.","tracks":[{"project":"genia-medco-coref","denotations":[{"id":"C1","span":{"begin":0,"end":21},"obj":"NP"},{"id":"C3","span":{"begin":57,"end":67},"obj":"NP"},{"id":"C2","span":{"begin":33,"end":81},"obj":"NP"},{"id":"C4","span":{"begin":123,"end":155},"obj":"NP"},{"id":"C5","span":{"begin":172,"end":186},"obj":"NP"},{"id":"C6","span":{"begin":187,"end":191},"obj":"NP"},{"id":"C7","span":{"begin":232,"end":259},"obj":"NP"},{"id":"C9","span":{"begin":298,"end":333},"obj":"NP"},{"id":"C8","span":{"begin":281,"end":333},"obj":"NP"},{"id":"C11","span":{"begin":386,"end":397},"obj":"NP"},{"id":"C10","span":{"begin":353,"end":397},"obj":"NP"},{"id":"C12","span":{"begin":461,"end":491},"obj":"NP"},{"id":"C14","span":{"begin":674,"end":684},"obj":"NP"},{"id":"C13","span":{"begin":674,"end":695},"obj":"NP"},{"id":"C15","span":{"begin":697,"end":700},"obj":"NP"},{"id":"C16","span":{"begin":830,"end":840},"obj":"NP"},{"id":"C17","span":{"begin":861,"end":923},"obj":"NP"},{"id":"C18","span":{"begin":1013,"end":1016},"obj":"NP"},{"id":"C20","span":{"begin":1033,"end":1066},"obj":"NP"},{"id":"C19","span":{"begin":1018,"end":1066},"obj":"NP"},{"id":"C21","span":{"begin":1085,"end":1088},"obj":"NP"},{"id":"C22","span":{"begin":1148,"end":1151},"obj":"NP"},{"id":"C23","span":{"begin":1186,"end":1191},"obj":"NP"},{"id":"C25","span":{"begin":1269,"end":1272},"obj":"NP"},{"id":"C24","span":{"begin":1269,"end":1284},"obj":"NP"},{"id":"C26","span":{"begin":1285,"end":1291},"obj":"NP"},{"id":"C27","span":{"begin":1321,"end":1326},"obj":"NP"},{"id":"C29","span":{"begin":1409,"end":1429},"obj":"NP"},{"id":"C28","span":{"begin":1334,"end":1429},"obj":"NP"},{"id":"C30","span":{"begin":1443,"end":1449},"obj":"NP"},{"id":"C32","span":{"begin":1457,"end":1467},"obj":"NP"},{"id":"C31","span":{"begin":1457,"end":1478},"obj":"NP"},{"id":"C33","span":{"begin":1512,"end":1515},"obj":"NP"},{"id":"C34","span":{"begin":1520,"end":1523},"obj":"NP"},{"id":"C36","span":{"begin":1539,"end":1549},"obj":"NP"},{"id":"C35","span":{"begin":1539,"end":1560},"obj":"NP"},{"id":"C37","span":{"begin":1593,"end":1614},"obj":"NP"},{"id":"C39","span":{"begin":1624,"end":1627},"obj":"NP"},{"id":"C40","span":{"begin":1632,"end":1635},"obj":"NP"},{"id":"C38","span":{"begin":1624,"end":1635},"obj":"NP"},{"id":"C41","span":{"begin":1646,"end":1651},"obj":"NP"},{"id":"C42","span":{"begin":1680,"end":1707},"obj":"NP"},{"id":"C43","span":{"begin":1758,"end":1761},"obj":"NP"},{"id":"C44","span":{"begin":1781,"end":1796},"obj":"NP"},{"id":"C45","span":{"begin":1955,"end":1981},"obj":"NP"}],"relations":[{"id":"R1","pred":"coref-relat","subj":"C6","obj":"C5"},{"id":"R2","pred":"coref-other","subj":"C7","obj":"C4"},{"id":"R3","pred":"coref-ident","subj":"C9","obj":"C3"},{"id":"R4","pred":"coref-other","subj":"C8","obj":"C2"},{"id":"R5","pred":"coref-ident","subj":"C11","obj":"C7"},{"id":"R6","pred":"coref-other","subj":"C10","obj":"C1"},{"id":"R7","pred":"coref-ident","subj":"C14","obj":"C9"},{"id":"R8","pred":"coref-ident","subj":"C15","obj":"C12"},{"id":"R9","pred":"coref-ident","subj":"C16","obj":"C14"},{"id":"R10","pred":"coref-appos","subj":"C19","obj":"C18"},{"id":"R11","pred":"coref-ident","subj":"C21","obj":"C15"},{"id":"R12","pred":"coref-ident","subj":"C22","obj":"C21"},{"id":"R13","pred":"coref-ident","subj":"C25","obj":"C18"},{"id":"R14","pred":"coref-pron","subj":"C26","obj":"C24"},{"id":"R15","pred":"coref-ident","subj":"C27","obj":"C23"},{"id":"R16","pred":"coref-other","subj":"C29","obj":"C17"},{"id":"R17","pred":"coref-pron","subj":"C30","obj":"C28"},{"id":"R18","pred":"coref-ident","subj":"C32","obj":"C16"},{"id":"R19","pred":"coref-ident","subj":"C31","obj":"C13"},{"id":"R20","pred":"coref-ident","subj":"C33","obj":"C25"},{"id":"R21","pred":"coref-ident","subj":"C36","obj":"C32"},{"id":"R22","pred":"coref-ident","subj":"C35","obj":"C31"},{"id":"R23","pred":"coref-other","subj":"C37","obj":"C10"},{"id":"R24","pred":"coref-ident","subj":"C39","obj":"C33"},{"id":"R25","pred":"coref-ident","subj":"C40","obj":"C34"},{"id":"R26","pred":"coref-pron","subj":"C41","obj":"C38"},{"id":"R27","pred":"coref-other","subj":"C42","obj":"C37"},{"id":"R28","pred":"coref-ident","subj":"C43","obj":"C22"},{"id":"R29","pred":"coref-ident","subj":"C44","obj":"C35"},{"id":"R30","pred":"coref-other","subj":"C45","obj":"C20"}],"attributes":[{"subj":"C1","pred":"source","obj":"genia-medco-coref"},{"subj":"C3","pred":"source","obj":"genia-medco-coref"},{"subj":"C2","pred":"source","obj":"genia-medco-coref"},{"subj":"C4","pred":"source","obj":"genia-medco-coref"},{"subj":"C5","pred":"source","obj":"genia-medco-coref"},{"subj":"C6","pred":"source","obj":"genia-medco-coref"},{"subj":"C7","pred":"source","obj":"genia-medco-coref"},{"subj":"C9","pred":"source","obj":"genia-medco-coref"},{"subj":"C8","pred":"source","obj":"genia-medco-coref"},{"subj":"C11","pred":"source","obj":"genia-medco-coref"},{"subj":"C10","pred":"source","obj":"genia-medco-coref"},{"subj":"C12","pred":"source","obj":"genia-medco-coref"},{"subj":"C14","pred":"source","obj":"genia-medco-coref"},{"subj":"C13","pred":"source","obj":"genia-medco-coref"},{"subj":"C15","pred":"source","obj":"genia-medco-coref"},{"subj":"C16","pred":"source","obj":"genia-medco-coref"},{"subj":"C17","pred":"source","obj":"genia-medco-coref"},{"subj":"C18","pred":"source","obj":"genia-medco-coref"},{"subj":"C20","pred":"source","obj":"genia-medco-coref"},{"subj":"C19","pred":"source","obj":"genia-medco-coref"},{"subj":"C21","pred":"source","obj":"genia-medco-coref"},{"subj":"C22","pred":"source","obj":"genia-medco-coref"},{"subj":"C23","pred":"source","obj":"genia-medco-coref"},{"subj":"C25","pred":"source","obj":"genia-medco-coref"},{"subj":"C24","pred":"source","obj":"genia-medco-coref"},{"subj":"C26","pred":"source","obj":"genia-medco-coref"},{"subj":"C27","pred":"source","obj":"genia-medco-coref"},{"subj":"C29","pred":"source","obj":"genia-medco-coref"},{"subj":"C28","pred":"source","obj":"genia-medco-coref"},{"subj":"C30","pred":"source","obj":"genia-medco-coref"},{"subj":"C32","pred":"source","obj":"genia-medco-coref"},{"subj":"C31","pred":"source","obj":"genia-medco-coref"},{"subj":"C33","pred":"source","obj":"genia-medco-coref"},{"subj":"C34","pred":"source","obj":"genia-medco-coref"},{"subj":"C36","pred":"source","obj":"genia-medco-coref"},{"subj":"C35","pred":"source","obj":"genia-medco-coref"},{"subj":"C37","pred":"source","obj":"genia-medco-coref"},{"subj":"C39","pred":"source","obj":"genia-medco-coref"},{"subj":"C40","pred":"source","obj":"genia-medco-coref"},{"subj":"C38","pred":"source","obj":"genia-medco-coref"},{"subj":"C41","pred":"source","obj":"genia-medco-coref"},{"subj":"C42","pred":"source","obj":"genia-medco-coref"},{"subj":"C43","pred":"source","obj":"genia-medco-coref"},{"subj":"C44","pred":"source","obj":"genia-medco-coref"},{"subj":"C45","pred":"source","obj":"genia-medco-coref"}]},{"project":"metamap-sample","denotations":[{"id":"T1","span":{"begin":87,"end":111},"obj":"C0079517"},{"id":"T2","span":{"begin":897,"end":906},"obj":"C0026473"},{"id":"T3","span":{"begin":251,"end":260},"obj":"C0026473"},{"id":"T4","span":{"begin":136,"end":145},"obj":"C0026473"},{"id":"T5","span":{"begin":282,"end":295},"obj":"C0040715"},{"id":"T6","span":{"begin":69,"end":81},"obj":"C0040715"},{"id":"T7","span":{"begin":1956,"end":1966},"obj":"C0079904"},{"id":"T8","span":{"begin":1540,"end":1550},"obj":"C0079904"},{"id":"T9","span":{"begin":1458,"end":1468},"obj":"C0079904"},{"id":"T10","span":{"begin":1042,"end":1052},"obj":"C0079904"},{"id":"T11","span":{"begin":831,"end":841},"obj":"C0079904"},{"id":"T12","span":{"begin":675,"end":685},"obj":"C0079904"},{"id":"T13","span":{"begin":324,"end":334},"obj":"C0079904"},{"id":"T14","span":{"begin":58,"end":68},"obj":"C0079904"},{"id":"T15","span":{"begin":1823,"end":1828},"obj":"C0030012"},{"id":"T16","span":{"begin":1696,"end":1701},"obj":"C0030012"},{"id":"T17","span":{"begin":1603,"end":1608},"obj":"C0030012"},{"id":"T18","span":{"begin":371,"end":376},"obj":"C0030012"},{"id":"T19","span":{"begin":1,"end":6},"obj":"C0030012"},{"id":"T20","span":{"begin":914,"end":924},"obj":"C0007600"},{"id":"T21","span":{"begin":146,"end":156},"obj":"C0007600"},{"id":"T22","span":{"begin":1759,"end":1762},"obj":"C0006506"},{"id":"T23","span":{"begin":1149,"end":1152},"obj":"C0006506"},{"id":"T24","span":{"begin":1086,"end":1089},"obj":"C0006506"},{"id":"T25","span":{"begin":698,"end":700},"obj":"C0006506"},{"id":"T26","span":{"begin":1570,"end":1579},"obj":"C0205263"},{"id":"T27","span":{"begin":1451,"end":1457},"obj":"C0205263"},{"id":"T28","span":{"begin":745,"end":752},"obj":"C0205263"},{"id":"T29","span":{"begin":50,"end":57},"obj":"C0205263"},{"id":"T30","span":{"begin":1633,"end":1636},"obj":"C0039654"},{"id":"T31","span":{"begin":1521,"end":1524},"obj":"C0039654"},{"id":"T32","span":{"begin":1093,"end":1096},"obj":"C0039654"},{"id":"T33","span":{"begin":733,"end":736},"obj":"C0039654"},{"id":"T34","span":{"begin":612,"end":615},"obj":"C0039654"},{"id":"T35","span":{"begin":1702,"end":1708},"obj":"C0449438"},{"id":"T36","span":{"begin":1609,"end":1615},"obj":"C0449438"},{"id":"T37","span":{"begin":377,"end":383},"obj":"C0449438"},{"id":"T38","span":{"begin":7,"end":13},"obj":"C0449438"},{"id":"T39","span":{"begin":1668,"end":1673},"obj":"C0007634"},{"id":"T40","span":{"begin":1313,"end":1321},"obj":"C0007634"},{"id":"T41","span":{"begin":635,"end":640},"obj":"C0007634"},{"id":"T42","span":{"begin":393,"end":398},"obj":"C0007634"},{"id":"T43","span":{"begin":193,"end":201},"obj":"C0007634"},{"id":"T44","span":{"begin":17,"end":22},"obj":"C0007634"},{"id":"T45","span":{"begin":1420,"end":1430},"obj":"C0600531"},{"id":"T46","span":{"begin":1108,"end":1118},"obj":"C0600531"},{"id":"T47","span":{"begin":989,"end":999},"obj":"C0600531"},{"id":"T48","span":{"begin":777,"end":789},"obj":"C0079516"},{"id":"T49","span":{"begin":1893,"end":1903},"obj":"C1879547"},{"id":"T50","span":{"begin":1787,"end":1797},"obj":"C1879547"},{"id":"T51","span":{"begin":1551,"end":1560},"obj":"C1879547"},{"id":"T52","span":{"begin":1469,"end":1479},"obj":"C1879547"},{"id":"T53","span":{"begin":686,"end":696},"obj":"C1879547"},{"id":"T54","span":{"begin":202,"end":212},"obj":"C1879547"},{"id":"T55","span":{"begin":1763,"end":1772},"obj":"C0039798"},{"id":"T56","span":{"begin":1380,"end":1384},"obj":"C0020281"},{"id":"T57","span":{"begin":523,"end":539},"obj":"C0969677"},{"id":"T58","span":{"begin":1001,"end":1010},"obj":"C0036536"},{"id":"T59","span":{"begin":1487,"end":1499},"obj":"C0700325"},{"id":"T60","span":{"begin":448,"end":460},"obj":"C0003402"},{"id":"T61","span":{"begin":1977,"end":1982},"obj":"C0017337"},{"id":"T62","span":{"begin":1528,"end":1531},"obj":"C1518422"},{"id":"T63","span":{"begin":1437,"end":1440},"obj":"C1518422"},{"id":"T64","span":{"begin":1198,"end":1201},"obj":"C1518422"},{"id":"T65","span":{"begin":724,"end":727},"obj":"C1518422"},{"id":"T66","span":{"begin":1392,"end":1406},"obj":"C0010454"},{"id":"T67","span":{"begin":1335,"end":1351},"obj":"C0242606"},{"id":"T68","span":{"begin":541,"end":550},"obj":"C0042874"},{"id":"T69","span":{"begin":1202,"end":1213},"obj":"C0017817"},{"id":"T70","span":{"begin":565,"end":580},"obj":"C0070417"},{"id":"T71","span":{"begin":1944,"end":1951},"obj":"C1561536"},{"id":"T72","span":{"begin":1226,"end":1236},"obj":"C1948023"},{"id":"T73","span":{"begin":1097,"end":1107},"obj":"C1948023"},{"id":"T74","span":{"begin":624,"end":634},"obj":"C1948023"},{"id":"T75","span":{"begin":1967,"end":1976},"obj":"C0851827"},{"id":"T76","span":{"begin":1053,"end":1062},"obj":"C0851827"},{"id":"T77","span":{"begin":339,"end":348},"obj":"C0851827"},{"id":"T78","span":{"begin":712,"end":714},"obj":"C1883351"},{"id":"T79","span":{"begin":552,"end":554},"obj":"C1883351"},{"id":"T80","span":{"begin":1724,"end":1736},"obj":"C0392747"},{"id":"T81","span":{"begin":1300,"end":1308},"obj":"C0392747"},{"id":"T82","span":{"begin":1653,"end":1659},"obj":"C1280500"},{"id":"T83","span":{"begin":1139,"end":1145},"obj":"C1280500"},{"id":"T84","span":{"begin":1660,"end":1664},"obj":"C0205171"},{"id":"T85","span":{"begin":728,"end":732},"obj":"C0205171"},{"id":"T86","span":{"begin":1241,"end":1253},"obj":"C0439819"},{"id":"T87","span":{"begin":595,"end":607},"obj":"C0439819"},{"id":"T88","span":{"begin":514,"end":518},"obj":"C0001128"},{"id":"T89","span":{"begin":1802,"end":1809},"obj":"C0700364"},{"id":"T90","span":{"begin":641,"end":647},"obj":"C1533157"},{"id":"T91","span":{"begin":1583,"end":1590},"obj":"C0443172"},{"id":"T92","span":{"begin":1641,"end":1646},"obj":"C0015264"},{"id":"T93","span":{"begin":652,"end":661},"obj":"C0542341"},{"id":"T94","span":{"begin":177,"end":187},"obj":"C1512571"},{"id":"T95","span":{"begin":408,"end":416},"obj":"C0359916"},{"id":"T96","span":{"begin":706,"end":711},"obj":"C0150312"},{"id":"T97","span":{"begin":1773,"end":1781},"obj":"C1292733"},{"id":"T98","span":{"begin":555,"end":559},"obj":"C1547282"},{"id":"T99","span":{"begin":715,"end":723},"obj":"C1260953"},{"id":"T100","span":{"begin":166,"end":172},"obj":"C0392366"},{"id":"T101","span":{"begin":403,"end":407},"obj":"C1273517"},{"id":"T102","span":{"begin":1500,"end":1507},"obj":"C1705535"},{"id":"T103","span":{"begin":1274,"end":1285},"obj":"C1292856"},{"id":"T104","span":{"begin":213,"end":219},"obj":"C0441471"},{"id":"T105","span":{"begin":1328,"end":1333},"obj":"C0441889"},{"id":"T106","span":{"begin":969,"end":985},"obj":"C2266866"},{"id":"T107","span":{"begin":1215,"end":1222},"obj":"C0456205"},{"id":"T108","span":{"begin":1175,"end":1183},"obj":"C0442805"},{"id":"T109","span":{"begin":940,"end":944},"obj":"C0205238"},{"id":"T110","span":{"begin":1368,"end":1376},"obj":"C1883712"},{"id":"T111","span":{"begin":1684,"end":1695},"obj":"C1548787"},{"id":"T112","span":{"begin":1532,"end":1536},"obj":"C2348269"},{"id":"T113","span":{"begin":1352,"end":1360},"obj":"C1301820"},{"id":"T114","span":{"begin":1674,"end":1677},"obj":"C1551058"},{"id":"T115","span":{"begin":1871,"end":1883},"obj":"C0679209"},{"id":"T116","span":{"begin":265,"end":273},"obj":"C0086597"},{"id":"T117","span":{"begin":799,"end":810},"obj":"C0521115"},{"id":"T118","span":{"begin":220,"end":229},"obj":"C2745955"},{"id":"T119","span":{"begin":662,"end":671},"obj":"C0725813"},{"id":"T120","span":{"begin":1598,"end":1602},"obj":"C1269647"},{"id":"T121","span":{"begin":418,"end":423},"obj":"C0023779"},{"id":"T122","span":{"begin":433,"end":438},"obj":"C1524075"},{"id":"T123","span":{"begin":424,"end":431},"obj":"C1749467"},{"id":"T124","span":{"begin":439,"end":447},"obj":"C1881704"},{"id":"T125","span":{"begin":1718,"end":1723},"obj":"C2826257"},{"id":"T126","span":{"begin":1744,"end":1753},"obj":"C0301630"},{"id":"T127","span":{"begin":1817,"end":1822},"obj":"C0205112"},{"id":"T128","span":{"begin":1829,"end":1840},"obj":"C0014653"},{"id":"T129","span":{"begin":1856,"end":1865},"obj":"C0030011"},{"id":"T130","span":{"begin":1129,"end":1138},"obj":"C0311404"},{"id":"T131","span":{"begin":1920,"end":1928},"obj":"C1704259"},{"id":"T132","span":{"begin":1888,"end":1892},"obj":"C0443225"},{"id":"T133","span":{"begin":1907,"end":1919},"obj":"C1160185"}],"attributes":[{"subj":"T1","pred":"source","obj":"metamap-sample"},{"subj":"T2","pred":"source","obj":"metamap-sample"},{"subj":"T3","pred":"source","obj":"metamap-sample"},{"subj":"T4","pred":"source","obj":"metamap-sample"},{"subj":"T5","pred":"source","obj":"metamap-sample"},{"subj":"T6","pred":"source","obj":"metamap-sample"},{"subj":"T7","pred":"source","obj":"metamap-sample"},{"subj":"T8","pred":"source","obj":"metamap-sample"},{"subj":"T9","pred":"source","obj":"metamap-sample"},{"subj":"T10","pred":"source","obj":"metamap-sample"},{"subj":"T11","pred":"source","obj":"metamap-sample"},{"subj":"T12","pred":"source","obj":"metamap-sample"},{"subj":"T13","pred":"source","obj":"metamap-sample"},{"subj":"T14","pred":"source","obj":"metamap-sample"},{"subj":"T15","pred":"source","obj":"metamap-sample"},{"subj":"T16","pred":"source","obj":"metamap-sample"},{"subj":"T17","pred":"source","obj":"metamap-sample"},{"subj":"T18","pred":"source","obj":"metamap-sample"},{"subj":"T19","pred":"source","obj":"metamap-sample"},{"subj":"T20","pred":"source","obj":"metamap-sample"},{"subj":"T21","pred":"source","obj":"metamap-sample"},{"subj":"T22","pred":"source","obj":"metamap-sample"},{"subj":"T23","pred":"source","obj":"metamap-sample"},{"subj":"T24","pred":"source","obj":"metamap-sample"},{"subj":"T25","pred":"source","obj":"metamap-sample"},{"subj":"T26","pred":"source","obj":"metamap-sample"},{"subj":"T27","pred":"source","obj":"metamap-sample"},{"subj":"T28","pred":"source","obj":"metamap-sample"},{"subj":"T29","pred":"source","obj":"metamap-sample"},{"subj":"T30","pred":"source","obj":"metamap-sample"},{"subj":"T31","pred":"source","obj":"metamap-sample"},{"subj":"T32","pred":"source","obj":"metamap-sample"},{"subj":"T33","pred":"source","obj":"metamap-sample"},{"subj":"T34","pred":"source","obj":"metamap-sample"},{"subj":"T35","pred":"source","obj":"metamap-sample"},{"subj":"T36","pred":"source","obj":"metamap-sample"},{"subj":"T37","pred":"source","obj":"metamap-sample"},{"subj":"T38","pred":"source","obj":"metamap-sample"},{"subj":"T39","pred":"source","obj":"metamap-sample"},{"subj":"T40","pred":"source","obj":"metamap-sample"},{"subj":"T41","pred":"source","obj":"metamap-sample"},{"subj":"T42","pred":"source","obj":"metamap-sample"},{"subj":"T43","pred":"source","obj":"metamap-sample"},{"subj":"T44","pred":"source","obj":"metamap-sample"},{"subj":"T45","pred":"source","obj":"metamap-sample"},{"subj":"T46","pred":"source","obj":"metamap-sample"},{"subj":"T47","pred":"source","obj":"metamap-sample"},{"subj":"T48","pred":"source","obj":"metamap-sample"},{"subj":"T49","pred":"source","obj":"metamap-sample"},{"subj":"T50","pred":"source","obj":"metamap-sample"},{"subj":"T51","pred":"source","obj":"metamap-sample"},{"subj":"T52","pred":"source","obj":"metamap-sample"},{"subj":"T53","pred":"source","obj":"metamap-sample"},{"subj":"T54","pred":"source","obj":"metamap-sample"},{"subj":"T55","pred":"source","obj":"metamap-sample"},{"subj":"T56","pred":"source","obj":"metamap-sample"},{"subj":"T57","pred":"source","obj":"metamap-sample"},{"subj":"T58","pred":"source","obj":"metamap-sample"},{"subj":"T59","pred":"source","obj":"metamap-sample"},{"subj":"T60","pred":"source","obj":"metamap-sample"},{"subj":"T61","pred":"source","obj":"metamap-sample"},{"subj":"T62","pred":"source","obj":"metamap-sample"},{"subj":"T63","pred":"source","obj":"metamap-sample"},{"subj":"T64","pred":"source","obj":"metamap-sample"},{"subj":"T65","pred":"source","obj":"metamap-sample"},{"subj":"T66","pred":"source","obj":"metamap-sample"},{"subj":"T67","pred":"source","obj":"metamap-sample"},{"subj":"T68","pred":"source","obj":"metamap-sample"},{"subj":"T69","pred":"source","obj":"metamap-sample"},{"subj":"T70","pred":"source","obj":"metamap-sample"},{"subj":"T71","pred":"source","obj":"metamap-sample"},{"subj":"T72","pred":"source","obj":"metamap-sample"},{"subj":"T73","pred":"source","obj":"metamap-sample"},{"subj":"T74","pred":"source","obj":"metamap-sample"},{"subj":"T75","pred":"source","obj":"metamap-sample"},{"subj":"T76","pred":"source","obj":"metamap-sample"},{"subj":"T77","pred":"source","obj":"metamap-sample"},{"subj":"T78","pred":"source","obj":"metamap-sample"},{"subj":"T79","pred":"source","obj":"metamap-sample"},{"subj":"T80","pred":"source","obj":"metamap-sample"},{"subj":"T81","pred":"source","obj":"metamap-sample"},{"subj":"T82","pred":"source","obj":"metamap-sample"},{"subj":"T83","pred":"source","obj":"metamap-sample"},{"subj":"T84","pred":"source","obj":"metamap-sample"},{"subj":"T85","pred":"source","obj":"metamap-sample"},{"subj":"T86","pred":"source","obj":"metamap-sample"},{"subj":"T87","pred":"source","obj":"metamap-sample"},{"subj":"T88","pred":"source","obj":"metamap-sample"},{"subj":"T89","pred":"source","obj":"metamap-sample"},{"subj":"T90","pred":"source","obj":"metamap-sample"},{"subj":"T91","pred":"source","obj":"metamap-sample"},{"subj":"T92","pred":"source","obj":"metamap-sample"},{"subj":"T93","pred":"source","obj":"metamap-sample"},{"subj":"T94","pred":"source","obj":"metamap-sample"},{"subj":"T95","pred":"source","obj":"metamap-sample"},{"subj":"T96","pred":"source","obj":"metamap-sample"},{"subj":"T97","pred":"source","obj":"metamap-sample"},{"subj":"T98","pred":"source","obj":"metamap-sample"},{"subj":"T99","pred":"source","obj":"metamap-sample"},{"subj":"T100","pred":"source","obj":"metamap-sample"},{"subj":"T101","pred":"source","obj":"metamap-sample"},{"subj":"T102","pred":"source","obj":"metamap-sample"},{"subj":"T103","pred":"source","obj":"metamap-sample"},{"subj":"T104","pred":"source","obj":"metamap-sample"},{"subj":"T105","pred":"source","obj":"metamap-sample"},{"subj":"T106","pred":"source","obj":"metamap-sample"},{"subj":"T107","pred":"source","obj":"metamap-sample"},{"subj":"T108","pred":"source","obj":"metamap-sample"},{"subj":"T109","pred":"source","obj":"metamap-sample"},{"subj":"T110","pred":"source","obj":"metamap-sample"},{"subj":"T111","pred":"source","obj":"metamap-sample"},{"subj":"T112","pred":"source","obj":"metamap-sample"},{"subj":"T113","pred":"source","obj":"metamap-sample"},{"subj":"T114","pred":"source","obj":"metamap-sample"},{"subj":"T115","pred":"source","obj":"metamap-sample"},{"subj":"T116","pred":"source","obj":"metamap-sample"},{"subj":"T117","pred":"source","obj":"metamap-sample"},{"subj":"T118","pred":"source","obj":"metamap-sample"},{"subj":"T119","pred":"source","obj":"metamap-sample"},{"subj":"T120","pred":"source","obj":"metamap-sample"},{"subj":"T121","pred":"source","obj":"metamap-sample"},{"subj":"T122","pred":"source","obj":"metamap-sample"},{"subj":"T123","pred":"source","obj":"metamap-sample"},{"subj":"T124","pred":"source","obj":"metamap-sample"},{"subj":"T125","pred":"source","obj":"metamap-sample"},{"subj":"T126","pred":"source","obj":"metamap-sample"},{"subj":"T127","pred":"source","obj":"metamap-sample"},{"subj":"T128","pred":"source","obj":"metamap-sample"},{"subj":"T129","pred":"source","obj":"metamap-sample"},{"subj":"T130","pred":"source","obj":"metamap-sample"},{"subj":"T131","pred":"source","obj":"metamap-sample"},{"subj":"T132","pred":"source","obj":"metamap-sample"},{"subj":"T133","pred":"source","obj":"metamap-sample"}]},{"project":"semrep-sample","denotations":[{"id":"E1-ti-1","span":{"begin":0,"end":5},"obj":"cui:C0030012"},{"id":"E2-ti-1","span":{"begin":6,"end":12},"obj":"cui:C0449438"},{"id":"E3-ti-1","span":{"begin":16,"end":21},"obj":"cui:C0007634"},{"id":"E4-ti-1","span":{"begin":49,"end":56},"obj":"cui:C0205263"},{"id":"E5-ti-1","span":{"begin":57,"end":67},"obj":"cui:C0079904"},{"id":"E6-ti-1","span":{"begin":86,"end":110},"obj":"cui:C0079517"},{"id":"E7-ti-1","span":{"begin":111,"end":119},"obj":"cui:C0439167"},{"id":"E8-ti-1","span":{"begin":123,"end":128},"obj":"cui:C0020114"},{"id":"E9-ti-1","span":{"begin":135,"end":144},"obj":"cui:C0026473"},{"id":"E10-ti-1","span":{"begin":145,"end":155},"obj":"cui:C0007600"},{"id":"E1-ab-1","span":{"begin":176,"end":186},"obj":"cui:C1512571"},{"id":"E2-ab-1","span":{"begin":192,"end":211},"obj":"cui:C1326120"},{"id":"E3-ab-1","span":{"begin":212,"end":218},"obj":"cui:C0441471"},{"id":"E4-ab-1","span":{"begin":232,"end":245},"obj":"cui:C0039194"},{"id":"E5-ab-1","span":{"begin":250,"end":259},"obj":"cui:C0026473"},{"id":"E6-ab-1","span":{"begin":302,"end":322},"obj":"cui:C0040648"},{"id":"E7-ab-1","span":{"begin":323,"end":333},"obj":"cui:C0079904"},{"id":"E8-ab-1","span":{"begin":370,"end":375},"obj":"cui:C0030012"},{"id":"E9-ab-1","span":{"begin":376,"end":382},"obj":"cui:C0449438"},{"id":"E10-ab-1","span":{"begin":392,"end":397},"obj":"cui:C0007634"},{"id":"T1","span":{"begin":338,"end":347},"obj":"AUGMENTS"},{"id":"E1-ab-2","span":{"begin":407,"end":415},"obj":"cui:C0359916"},{"id":"E2-ab-2","span":{"begin":417,"end":422},"obj":"cui:C0023779"},{"id":"E3-ab-2","span":{"begin":447,"end":459},"obj":"cui:C0003402"},{"id":"E4-ab-2","span":{"begin":461,"end":485},"obj":"cui:C0006506"},{"id":"E5-ab-2","span":{"begin":487,"end":490},"obj":"cui:C0006506"},{"id":"E6-ab-2","span":{"begin":513,"end":517},"obj":"cui:C0001128"},{"id":"E7-ab-2","span":{"begin":522,"end":538},"obj":"cui:C0969677"},{"id":"E8-ab-2","span":{"begin":540,"end":549},"obj":"cui:C0042874"},{"id":"E9-ab-2","span":{"begin":564,"end":579},"obj":"cui:C0070417"},{"id":"E10-ab-2","span":{"begin":594,"end":606},"obj":"cui:C0439819"},{"id":"E11-ab-2","span":{"begin":611,"end":614},"obj":"cui:C0048451"},{"id":"E12-ab-2","span":{"begin":619,"end":622},"obj":"cui:C0812246"},{"id":"E13-ab-2","span":{"begin":634,"end":639},"obj":"cui:C0007634"},{"id":"E14-ab-2","span":{"begin":651,"end":660},"obj":"cui:C0542341"},{"id":"E15-ab-2","span":{"begin":674,"end":684},"obj":"cui:C0079904"},{"id":"T2","span":{"begin":447,"end":485},"obj":"ISA"},{"id":"T3","span":{"begin":522,"end":549},"obj":"ISA"},{"id":"T4","span":{"begin":685,"end":695},"obj":"STIMULATES"},{"id":"E1-ab-3","span":{"begin":697,"end":700},"obj":"cui:C0006506"},{"id":"E2-ab-3","span":{"begin":723,"end":726},"obj":"cui:C1518422"},{"id":"E3-ab-3","span":{"begin":732,"end":735},"obj":"cui:C0048451"},{"id":"E4-ab-3","span":{"begin":740,"end":743},"obj":"cui:C0812246"},{"id":"E5-ab-3","span":{"begin":744,"end":751},"obj":"cui:C0205263"},{"id":"E6-ab-3","span":{"begin":776,"end":788},"obj":"cui:C0079516"},{"id":"E7-ab-3","span":{"begin":789,"end":797},"obj":"cui:C0439167"},{"id":"E8-ab-3","span":{"begin":798,"end":809},"obj":"cui:C1516780"},{"id":"E9-ab-3","span":{"begin":830,"end":840},"obj":"cui:C0079904"},{"id":"E10-ab-3","span":{"begin":849,"end":857},"obj":"cui:C0439167"},{"id":"E11-ab-3","span":{"begin":896,"end":905},"obj":"cui:C0026473"},{"id":"E12-ab-3","span":{"begin":913,"end":923},"obj":"cui:C0007600"},{"id":"T5","span":{"begin":714,"end":722},"obj":"INHIBITS"},{"id":"E1-ab-4","span":{"begin":939,"end":943},"obj":"cui:C0205238"},{"id":"E2-ab-4","span":{"begin":953,"end":956},"obj":"cui:C1367009"},{"id":"E3-ab-4","span":{"begin":957,"end":966},"obj":"entrez:6647"},{"id":"E4-ab-4","span":{"begin":976,"end":984},"obj":"cui:C0439167"},{"id":"E5-ab-4","span":{"begin":988,"end":998},"obj":"cui:C0600531"},{"id":"E1-ab-5","span":{"begin":1000,"end":1009},"obj":"cui:C0015283"},{"id":"E2-ab-5","span":{"begin":1013,"end":1016},"obj":"cui:C0812246"},{"id":"E3-ab-5","span":{"begin":1022,"end":1029},"obj":"cui:C1514468"},{"id":"E4-ab-5","span":{"begin":1041,"end":1051},"obj":"cui:C0079904"},{"id":"E5-ab-5","span":{"begin":1062,"end":1066},"obj":"cui:C0017337"},{"id":"E6-ab-5","span":{"begin":1085,"end":1088},"obj":"cui:C0006506"},{"id":"E7-ab-5","span":{"begin":1092,"end":1095},"obj":"cui:C0048451"},{"id":"E8-ab-5","span":{"begin":1107,"end":1117},"obj":"cui:C0600531"},{"id":"T6","span":{"begin":1052,"end":1061},"obj":"STIMULATES"},{"id":"T7","span":{"begin":1089,"end":1091},"obj":"LOCATION_OF"},{"id":"E1-ab-6","span":{"begin":1128,"end":1137},"obj":"cui:C0311404"},{"id":"E2-ab-6","span":{"begin":1138,"end":1144},"obj":"cui:C1280500"},{"id":"E3-ab-6","span":{"begin":1148,"end":1151},"obj":"cui:C0006506"},{"id":"E4-ab-6","span":{"begin":1174,"end":1182},"obj":"cui:C0442805"},{"id":"E5-ab-6","span":{"begin":1186,"end":1191},"obj":"cui:C0038734"},{"id":"E6-ab-6","span":{"begin":1197,"end":1200},"obj":"cui:C1518422"},{"id":"E7-ab-6","span":{"begin":1201,"end":1212},"obj":"cui:C0017817"},{"id":"E8-ab-6","span":{"begin":1240,"end":1252},"obj":"cui:C0439819"},{"id":"E9-ab-6","span":{"begin":1253,"end":1259},"obj":"cui:C0039194"},{"id":"E10-ab-6","span":{"begin":1269,"end":1272},"obj":"cui:C0812246"},{"id":"E11-ab-6","span":{"begin":1273,"end":1284},"obj":"cui:C1292856"},{"id":"E12-ab-6","span":{"begin":1312,"end":1320},"obj":"cui:C0178539"},{"id":"E13-ab-6","span":{"begin":1321,"end":1326},"obj":"cui:C0038734"},{"id":"T8","span":{"begin":1174,"end":1182},"obj":"STIMULATES"},{"id":"T9","span":{"begin":1273,"end":1284},"obj":"STIMULATES"},{"id":"E1-ab-7","span":{"begin":1334,"end":1350},"obj":"cui:C0242606"},{"id":"E2-ab-7","span":{"begin":1367,"end":1375},"obj":"cui:C0442796"},{"id":"E3-ab-7","span":{"begin":1379,"end":1383},"obj":"cui:C0020281"},{"id":"E4-ab-7","span":{"begin":1391,"end":1405},"obj":"cui:C0010454"},{"id":"E5-ab-7","span":{"begin":1419,"end":1429},"obj":"cui:C0600531"},{"id":"E6-ab-7","span":{"begin":1436,"end":1439},"obj":"cui:C1518422"},{"id":"E7-ab-7","span":{"begin":1457,"end":1467},"obj":"cui:C0079904"},{"id":"E1-ab-8","span":{"begin":1512,"end":1515},"obj":"cui:C0812246"},{"id":"E2-ab-8","span":{"begin":1520,"end":1523},"obj":"cui:C0048451"},{"id":"E3-ab-8","span":{"begin":1527,"end":1530},"obj":"cui:C1518422"},{"id":"E4-ab-8","span":{"begin":1539,"end":1549},"obj":"cui:C0079904"},{"id":"E5-ab-8","span":{"begin":1569,"end":1578},"obj":"cui:C0857127"},{"id":"E6-ab-8","span":{"begin":1582,"end":1589},"obj":"cui:C0392747"},{"id":"E7-ab-8","span":{"begin":1597,"end":1601},"obj":"cui:C0007634"},{"id":"E8-ab-8","span":{"begin":1602,"end":1607},"obj":"cui:C0030012"},{"id":"E9-ab-8","span":{"begin":1608,"end":1614},"obj":"cui:C0449438"},{"id":"T10","span":{"begin":1550,"end":1560},"obj":"STIMULATES"},{"id":"T11","span":{"begin":1550,"end":1560},"obj":"STIMULATES"},{"id":"E1-ab-9","span":{"begin":1624,"end":1627},"obj":"cui:C0812246"},{"id":"E2-ab-9","span":{"begin":1632,"end":1635},"obj":"cui:C0048451"},{"id":"E3-ab-9","span":{"begin":1652,"end":1658},"obj":"cui:C1280500"},{"id":"E4-ab-9","span":{"begin":1667,"end":1672},"obj":"cui:C0007634"},{"id":"E5-ab-9","span":{"begin":1683,"end":1694},"obj":"cui:C1548787"},{"id":"E6-ab-9","span":{"begin":1695,"end":1700},"obj":"cui:C0030012"},{"id":"E7-ab-9","span":{"begin":1701,"end":1707},"obj":"cui:C0449438"},{"id":"E8-ab-9","span":{"begin":1717,"end":1722},"obj":"cui:C0332152"},{"id":"E9-ab-9","span":{"begin":1723,"end":1735},"obj":"cui:C1522413"},{"id":"E10-ab-9","span":{"begin":1758,"end":1761},"obj":"cui:C0006506"},{"id":"E1-ab-10","span":{"begin":1816,"end":1821},"obj":"cui:C0205112"},{"id":"E2-ab-10","span":{"begin":1822,"end":1827},"obj":"cui:C0030012"},{"id":"E3-ab-10","span":{"begin":1828,"end":1839},"obj":"cui:C0014653"},{"id":"E4-ab-10","span":{"begin":1855,"end":1864},"obj":"cui:C0030011"},{"id":"E5-ab-10","span":{"begin":1870,"end":1882},"obj":"cui:C0679209"},{"id":"E6-ab-10","span":{"begin":1887,"end":1891},"obj":"cui:C0443225"},{"id":"E7-ab-10","span":{"begin":1906,"end":1918},"obj":"cui:C1160185"},{"id":"E8-ab-10","span":{"begin":1943,"end":1951},"obj":"cui:C0439167"},{"id":"E9-ab-10","span":{"begin":1955,"end":1965},"obj":"cui:C0079904"},{"id":"E10-ab-10","span":{"begin":1976,"end":1981},"obj":"cui:C0017337"}],"relations":[{"id":"R1","pred":"subjectOf","subj":"E7-ab-1","obj":"T1"},{"id":"R2","pred":"objectOf","subj":"E8-ab-1","obj":"T1"},{"id":"R3","pred":"subjectOf","subj":"E4-ab-2","obj":"T2"},{"id":"R4","pred":"objectOf","subj":"E3-ab-2","obj":"T2"},{"id":"R5","pred":"subjectOf","subj":"E7-ab-2","obj":"T3"},{"id":"R6","pred":"objectOf","subj":"E8-ab-2","obj":"T3"},{"id":"R7","pred":"subjectOf","subj":"E11-ab-2","obj":"T4"},{"id":"R8","pred":"objectOf","subj":"E15-ab-2","obj":"T4"},{"id":"R9","pred":"subjectOf","subj":"E1-ab-3","obj":"T5"},{"id":"R10","pred":"objectOf","subj":"E3-ab-3","obj":"T5"},{"id":"R11","pred":"subjectOf","subj":"E2-ab-5","obj":"T6"},{"id":"R12","pred":"objectOf","subj":"E6-ab-5","obj":"T6"},{"id":"R13","pred":"subjectOf","subj":"E8-ab-5","obj":"T7"},{"id":"R14","pred":"objectOf","subj":"E6-ab-5","obj":"T7"},{"id":"R15","pred":"subjectOf","subj":"E13-ab-6","obj":"T8"},{"id":"R16","pred":"objectOf","subj":"E5-ab-6","obj":"T8"},{"id":"R17","pred":"subjectOf","subj":"E7-ab-6","obj":"T9"},{"id":"R18","pred":"objectOf","subj":"E10-ab-6","obj":"T9"},{"id":"R19","pred":"subjectOf","subj":"E2-ab-8","obj":"T10"},{"id":"R20","pred":"objectOf","subj":"E4-ab-8","obj":"T10"},{"id":"R21","pred":"subjectOf","subj":"E1-ab-8","obj":"T11"},{"id":"R22","pred":"objectOf","subj":"E4-ab-8","obj":"T11"}],"attributes":[{"subj":"E1-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E2-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E3-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E4-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E5-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E6-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E7-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E8-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E9-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E10-ti-1","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-1","pred":"source","obj":"semrep-sample"},{"subj":"T1","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E11-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E12-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E13-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E14-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"E15-ab-2","pred":"source","obj":"semrep-sample"},{"subj":"T2","pred":"source","obj":"semrep-sample"},{"subj":"T3","pred":"source","obj":"semrep-sample"},{"subj":"T4","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E11-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"E12-ab-3","pred":"source","obj":"semrep-sample"},{"subj":"T5","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-4","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-5","pred":"source","obj":"semrep-sample"},{"subj":"T6","pred":"source","obj":"semrep-sample"},{"subj":"T7","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E11-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E12-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"E13-ab-6","pred":"source","obj":"semrep-sample"},{"subj":"T8","pred":"source","obj":"semrep-sample"},{"subj":"T9","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-7","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-8","pred":"source","obj":"semrep-sample"},{"subj":"T10","pred":"source","obj":"semrep-sample"},{"subj":"T11","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-9","pred":"source","obj":"semrep-sample"},{"subj":"E1-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E2-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E3-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E4-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E5-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E6-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E7-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E8-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E9-ab-10","pred":"source","obj":"semrep-sample"},{"subj":"E10-ab-10","pred":"source","obj":"semrep-sample"}]},{"project":"jnlpba-st-training","denotations":[{"id":"T1","span":{"begin":57,"end":67},"obj":"protein"},{"id":"T2","span":{"begin":86,"end":110},"obj":"DNA"},{"id":"T3","span":{"begin":123,"end":155},"obj":"cell_line"},{"id":"T4","span":{"begin":232,"end":245},"obj":"cell_type"},{"id":"T5","span":{"begin":250,"end":259},"obj":"cell_type"},{"id":"T6","span":{"begin":302,"end":333},"obj":"protein"},{"id":"T7","span":{"begin":594,"end":639},"obj":"cell_line"},{"id":"T8","span":{"begin":674,"end":684},"obj":"protein"},{"id":"T9","span":{"begin":830,"end":840},"obj":"protein"},{"id":"T10","span":{"begin":866,"end":882},"obj":"cell_line"},{"id":"T11","span":{"begin":884,"end":890},"obj":"cell_line"},{"id":"T12","span":{"begin":896,"end":923},"obj":"cell_line"},{"id":"T13","span":{"begin":988,"end":998},"obj":"cell_line"},{"id":"T14","span":{"begin":1013,"end":1016},"obj":"protein"},{"id":"T15","span":{"begin":1041,"end":1066},"obj":"DNA"},{"id":"T16","span":{"begin":1092,"end":1117},"obj":"cell_line"},{"id":"T17","span":{"begin":1225,"end":1259},"obj":"cell_line"},{"id":"T18","span":{"begin":1269,"end":1272},"obj":"protein"},{"id":"T19","span":{"begin":1409,"end":1415},"obj":"cell_line"},{"id":"T20","span":{"begin":1419,"end":1429},"obj":"cell_line"},{"id":"T21","span":{"begin":1457,"end":1467},"obj":"protein"},{"id":"T22","span":{"begin":1512,"end":1515},"obj":"protein"},{"id":"T23","span":{"begin":1520,"end":1523},"obj":"protein"},{"id":"T24","span":{"begin":1539,"end":1549},"obj":"protein"},{"id":"T25","span":{"begin":1624,"end":1627},"obj":"protein"},{"id":"T26","span":{"begin":1632,"end":1635},"obj":"protein"},{"id":"T27","span":{"begin":1955,"end":1981},"obj":"DNA"}],"attributes":[{"subj":"T1","pred":"source","obj":"jnlpba-st-training"},{"subj":"T2","pred":"source","obj":"jnlpba-st-training"},{"subj":"T3","pred":"source","obj":"jnlpba-st-training"},{"subj":"T4","pred":"source","obj":"jnlpba-st-training"},{"subj":"T5","pred":"source","obj":"jnlpba-st-training"},{"subj":"T6","pred":"source","obj":"jnlpba-st-training"},{"subj":"T7","pred":"source","obj":"jnlpba-st-training"},{"subj":"T8","pred":"source","obj":"jnlpba-st-training"},{"subj":"T9","pred":"source","obj":"jnlpba-st-training"},{"subj":"T10","pred":"source","obj":"jnlpba-st-training"},{"subj":"T11","pred":"source","obj":"jnlpba-st-training"},{"subj":"T12","pred":"source","obj":"jnlpba-st-training"},{"subj":"T13","pred":"source","obj":"jnlpba-st-training"},{"subj":"T14","pred":"source","obj":"jnlpba-st-training"},{"subj":"T15","pred":"source","obj":"jnlpba-st-training"},{"subj":"T16","pred":"source","obj":"jnlpba-st-training"},{"subj":"T17","pred":"source","obj":"jnlpba-st-training"},{"subj":"T18","pred":"source","obj":"jnlpba-st-training"},{"subj":"T19","pred":"source","obj":"jnlpba-st-training"},{"subj":"T20","pred":"source","obj":"jnlpba-st-training"},{"subj":"T21","pred":"source","obj":"jnlpba-st-training"},{"subj":"T22","pred":"source","obj":"jnlpba-st-training"},{"subj":"T23","pred":"source","obj":"jnlpba-st-training"},{"subj":"T24","pred":"source","obj":"jnlpba-st-training"},{"subj":"T25","pred":"source","obj":"jnlpba-st-training"},{"subj":"T26","pred":"source","obj":"jnlpba-st-training"},{"subj":"T27","pred":"source","obj":"jnlpba-st-training"}]},{"project":"pubmed-sentences-benchmark","denotations":[{"id":"S1","span":{"begin":0,"end":156},"obj":"Sentence"},{"id":"S2","span":{"begin":157,"end":398},"obj":"Sentence"},{"id":"S3","span":{"begin":399,"end":696},"obj":"Sentence"},{"id":"S4","span":{"begin":697,"end":924},"obj":"Sentence"},{"id":"S5","span":{"begin":925,"end":999},"obj":"Sentence"},{"id":"S6","span":{"begin":1000,"end":1118},"obj":"Sentence"},{"id":"S7","span":{"begin":1119,"end":1333},"obj":"Sentence"},{"id":"S8","span":{"begin":1334,"end":1479},"obj":"Sentence"},{"id":"S9","span":{"begin":1480,"end":1615},"obj":"Sentence"},{"id":"S10","span":{"begin":1616,"end":1797},"obj":"Sentence"},{"id":"S11","span":{"begin":1798,"end":1982},"obj":"Sentence"}],"attributes":[{"subj":"S1","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S2","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S3","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S4","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S5","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S6","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S7","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S8","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S9","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S10","pred":"source","obj":"pubmed-sentences-benchmark"},{"subj":"S11","pred":"source","obj":"pubmed-sentences-benchmark"}]},{"project":"GENIAcorpus","denotations":[{"id":"T1","span":{"begin":0,"end":12},"obj":"other_name"},{"id":"T2","span":{"begin":57,"end":67},"obj":"protein_molecule"},{"id":"T3","span":{"begin":86,"end":110},"obj":"DNA_domain_or_region"},{"id":"T4","span":{"begin":192,"end":218},"obj":"other_name"},{"id":"T5","span":{"begin":232,"end":245},"obj":"cell_type"},{"id":"T6","span":{"begin":250,"end":259},"obj":"cell_type"},{"id":"T7","span":{"begin":302,"end":322},"obj":"protein_molecule"},{"id":"T8","span":{"begin":323,"end":333},"obj":"protein_molecule"},{"id":"T9","span":{"begin":357,"end":382},"obj":"other_name"},{"id":"T10","span":{"begin":407,"end":459},"obj":"other_organic_compound"},{"id":"T11","span":{"begin":461,"end":485},"obj":"other_organic_compound"},{"id":"T12","span":{"begin":487,"end":490},"obj":"other_organic_compound"},{"id":"T13","span":{"begin":493,"end":517},"obj":"other_organic_compound"},{"id":"T14","span":{"begin":522,"end":538},"obj":"lipid"},{"id":"T15","span":{"begin":540,"end":549},"obj":"lipid"},{"id":"T16","span":{"begin":674,"end":684},"obj":"protein_molecule"},{"id":"T17","span":{"begin":697,"end":700},"obj":"other_organic_compound"},{"id":"T18","span":{"begin":830,"end":840},"obj":"protein_molecule"},{"id":"T19","span":{"begin":866,"end":882},"obj":"cell_line"},{"id":"T20","span":{"begin":884,"end":890},"obj":"cell_line"},{"id":"T21","span":{"begin":896,"end":907},"obj":"cell_line"},{"id":"T22","span":{"begin":907,"end":911},"obj":"cell_line"},{"id":"T23","span":{"begin":988,"end":992},"obj":"cell_line"},{"id":"T24","span":{"begin":1013,"end":1016},"obj":"protein_molecule"},{"id":"T25","span":{"begin":1041,"end":1051},"obj":"protein_molecule"},{"id":"T26","span":{"begin":1085,"end":1088},"obj":"other_organic_compound"},{"id":"T27","span":{"begin":1092,"end":1106},"obj":"cell_line"},{"id":"T28","span":{"begin":1107,"end":1117},"obj":"cell_line"},{"id":"T29","span":{"begin":1123,"end":1144},"obj":"other_name"},{"id":"T30","span":{"begin":1148,"end":1151},"obj":"other_organic_compound"},{"id":"T31","span":{"begin":1186,"end":1191},"obj":"other_organic_compound"},{"id":"T32","span":{"begin":1201,"end":1212},"obj":"peptide"},{"id":"T33","span":{"begin":1225,"end":1235},"obj":"cell_line"},{"id":"T34","span":{"begin":1240,"end":1259},"obj":"cell_line"},{"id":"T35","span":{"begin":1269,"end":1272},"obj":"protein_family_or_group"},{"id":"T36","span":{"begin":1312,"end":1320},"obj":"other_name"},{"id":"T37","span":{"begin":1321,"end":1326},"obj":"other_organic_compound"},{"id":"T38","span":{"begin":1334,"end":1350},"obj":"other_name"},{"id":"T39","span":{"begin":1379,"end":1383},"obj":"inorganic"},{"id":"T40","span":{"begin":1391,"end":1405},"obj":"other_name"},{"id":"T41","span":{"begin":1409,"end":1415},"obj":"cell_line"},{"id":"T42","span":{"begin":1419,"end":1429},"obj":"cell_line"},{"id":"T43","span":{"begin":1457,"end":1467},"obj":"protein_molecule"},{"id":"T44","span":{"begin":1512,"end":1515},"obj":"protein_molecule"},{"id":"T45","span":{"begin":1520,"end":1523},"obj":"protein_molecule"},{"id":"T46","span":{"begin":1539,"end":1549},"obj":"protein_molecule"},{"id":"T47","span":{"begin":1624,"end":1627},"obj":"protein_molecule"},{"id":"T48","span":{"begin":1632,"end":1635},"obj":"protein_molecule"},{"id":"T49","span":{"begin":1695,"end":1707},"obj":"other_name"},{"id":"T50","span":{"begin":1758,"end":1761},"obj":"other_organic_compound"},{"id":"T51","span":{"begin":1816,"end":1839},"obj":"other_name"},{"id":"T52","span":{"begin":1955,"end":1965},"obj":"protein_molecule"}],"attributes":[{"subj":"T1","pred":"source","obj":"GENIAcorpus"},{"subj":"T2","pred":"source","obj":"GENIAcorpus"},{"subj":"T3","pred":"source","obj":"GENIAcorpus"},{"subj":"T4","pred":"source","obj":"GENIAcorpus"},{"subj":"T5","pred":"source","obj":"GENIAcorpus"},{"subj":"T6","pred":"source","obj":"GENIAcorpus"},{"subj":"T7","pred":"source","obj":"GENIAcorpus"},{"subj":"T8","pred":"source","obj":"GENIAcorpus"},{"subj":"T9","pred":"source","obj":"GENIAcorpus"},{"subj":"T10","pred":"source","obj":"GENIAcorpus"},{"subj":"T11","pred":"source","obj":"GENIAcorpus"},{"subj":"T12","pred":"source","obj":"GENIAcorpus"},{"subj":"T13","pred":"source","obj":"GENIAcorpus"},{"subj":"T14","pred":"source","obj":"GENIAcorpus"},{"subj":"T15","pred":"source","obj":"GENIAcorpus"},{"subj":"T16","pred":"source","obj":"GENIAcorpus"},{"subj":"T17","pred":"source","obj":"GENIAcorpus"},{"subj":"T18","pred":"source","obj":"GENIAcorpus"},{"subj":"T19","pred":"source","obj":"GENIAcorpus"},{"subj":"T20","pred":"source","obj":"GENIAcorpus"},{"subj":"T21","pred":"source","obj":"GENIAcorpus"},{"subj":"T22","pred":"source","obj":"GENIAcorpus"},{"subj":"T23","pred":"source","obj":"GENIAcorpus"},{"subj":"T24","pred":"source","obj":"GENIAcorpus"},{"subj":"T25","pred":"source","obj":"GENIAcorpus"},{"subj":"T26","pred":"source","obj":"GENIAcorpus"},{"subj":"T27","pred":"source","obj":"GENIAcorpus"},{"subj":"T28","pred":"source","obj":"GENIAcorpus"},{"subj":"T29","pred":"source","obj":"GENIAcorpus"},{"subj":"T30","pred":"source","obj":"GENIAcorpus"},{"subj":"T31","pred":"source","obj":"GENIAcorpus"},{"subj":"T32","pred":"source","obj":"GENIAcorpus"},{"subj":"T33","pred":"source","obj":"GENIAcorpus"},{"subj":"T34","pred":"source","obj":"GENIAcorpus"},{"subj":"T35","pred":"source","obj":"GENIAcorpus"},{"subj":"T36","pred":"source","obj":"GENIAcorpus"},{"subj":"T37","pred":"source","obj":"GENIAcorpus"},{"subj":"T38","pred":"source","obj":"GENIAcorpus"},{"subj":"T39","pred":"source","obj":"GENIAcorpus"},{"subj":"T40","pred":"source","obj":"GENIAcorpus"},{"subj":"T41","pred":"source","obj":"GENIAcorpus"},{"subj":"T42","pred":"source","obj":"GENIAcorpus"},{"subj":"T43","pred":"source","obj":"GENIAcorpus"},{"subj":"T44","pred":"source","obj":"GENIAcorpus"},{"subj":"T45","pred":"source","obj":"GENIAcorpus"},{"subj":"T46","pred":"source","obj":"GENIAcorpus"},{"subj":"T47","pred":"source","obj":"GENIAcorpus"},{"subj":"T48","pred":"source","obj":"GENIAcorpus"},{"subj":"T49","pred":"source","obj":"GENIAcorpus"},{"subj":"T50","pred":"source","obj":"GENIAcorpus"},{"subj":"T51","pred":"source","obj":"GENIAcorpus"},{"subj":"T52","pred":"source","obj":"GENIAcorpus"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"genia-medco-coref","color":"#de93ec","default":true},{"id":"metamap-sample","color":"#93ecc4"},{"id":"semrep-sample","color":"#ecaa93"},{"id":"jnlpba-st-training","color":"#9395ec"},{"id":"pubmed-sentences-benchmark","color":"#b0ec93"},{"id":"GENIAcorpus","color":"#ec93ca"}]}]}}