PubMed:1372388
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 2-39 | protein | denotes | lymphoid cell-specific nuclear factor |
| T2 | 51-70 | protein | denotes | c-Rel-like proteins |
| T3 | 101-137 | DNA | denotes | interleukin-6 kappa B-related motifs |
| T4 | 172-186 | cell_type | denotes | lymphoid cells |
| T5 | 192-215 | protein | denotes | proto-oncoprotein c-Rel |
| T6 | 235-285 | protein | denotes | nuclear factor kappa B transcription factor family |
| T7 | 306-309 | protein | denotes | p50 |
| T8 | 314-326 | protein | denotes | p65 subunits |
| T9 | 330-352 | protein | denotes | nuclear factor kappa B |
| T10 | 372-377 | protein | denotes | c-Rel |
| T11 | 387-400 | DNA | denotes | kappa B sites |
| T12 | 404-414 | protein | denotes | homodimers |
| T13 | 426-438 | protein | denotes | heterodimers |
| T14 | 444-447 | protein | denotes | p50 |
| T15 | 455-465 | protein | denotes | homodimers |
| T16 | 470-482 | protein | denotes | heterodimers |
| T17 | 550-564 | DNA | denotes | kappa B motifs |
| T18 | 585-600 | protein | denotes | c-Rel homodimer |
| T19 | 625-638 | protein | denotes | interleukin-6 |
| T20 | 640-644 | protein | denotes | IL-6 |
| T21 | 650-679 | DNA | denotes | beta interferon kappa B sites |
| T22 | 714-717 | protein | denotes | p50 |
| T23 | 748-785 | protein | denotes | lymphoid cell-specific nuclear factor |
| T24 | 808-813 | protein | denotes | c-Rel |
| T25 | 822-834 | protein | denotes | p50 epitopes |
| T26 | 856-886 | protein | denotes | IL-6 kappa B binding factor II |
| T27 | 911-926 | protein | denotes | c-Rel homodimer |
| T28 | 965-1000 | DNA | denotes | IL-6 kappa B-related kappa B motifs |
| T29 | 1049-1067 | DNA | denotes | IL-6 kappa B motif |
| T30 | 1090-1135 | DNA | denotes | IL-1/tumor necrosis factor-responsive element |
| T31 | 1139-1156 | cell_type | denotes | nonlymphoid cells |
| T32 | 1200-1214 | cell_type | denotes | lymphoid cells |
| T33 | 1225-1243 | cell_line | denotes | Jurkat T-cell line |
| T34 | 1275-1305 | protein | denotes | IL-6 kappa B binding factor II |
| T35 | 1344-1379 | DNA | denotes | IL-6 kappa B-related kappa B motifs |
| T36 | 1383-1397 | cell_type | denotes | lymphoid cells |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-187 | Sentence | denotes | A lymphoid cell-specific nuclear factor containing c-Rel-like proteins preferentially interacts with interleukin-6 kappa B-related motifs whose activities are repressed in lymphoid cells. |
| S2 | 188-353 | Sentence | denotes | The proto-oncoprotein c-Rel is a member of the nuclear factor kappa B transcription factor family, which includes the p50 and p65 subunits of nuclear factor kappa B. |
| S3 | 354-448 | Sentence | denotes | We show here that c-Rel binds to kappa B sites as homodimers as well as heterodimers with p50. |
| S4 | 449-565 | Sentence | denotes | These homodimers and heterodimers show distinct DNA-binding specificities and affinities for various kappa B motifs. |
| S5 | 566-680 | Sentence | denotes | In particular, the c-Rel homodimer has a high affinity for interleukin-6 (IL-6) and beta interferon kappa B sites. |
| S6 | 681-1001 | Sentence | denotes | In spite of its association with p50 in vitro, however, we found a lymphoid cell-specific nuclear factor in vivo that contains c-Rel but not p50 epitopes; this factor, termed IL-6 kappa B binding factor II, appears to contain the c-Rel homodimer and preferentially recognizes several IL-6 kappa B-related kappa B motifs. |
| S7 | 1002-1244 | Sentence | denotes | Although it has been previously shown that the IL-6 kappa B motif functions as a potent IL-1/tumor necrosis factor-responsive element in nonlymphoid cells, its activity was found to be repressed in lymphoid cells such as a Jurkat T-cell line. |
| S8 | 1245-1398 | Sentence | denotes | We also present evidence that IL-6 kappa B binding factor II functions as a repressor specific for IL-6 kappa B-related kappa B motifs in lymphoid cells. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-39 | NP | denotes | A lymphoid cell-specific nuclear factor |
| C3 | 101-114 | NP | denotes | interleukin-6 |
| C2 | 101-137 | NP | denotes | interleukin-6 kappa B-related motifs |
| C4 | 138-143 | NP | denotes | whose |
| C5 | 172-186 | NP | denotes | lymphoid cells |
| C6 | 188-215 | NP | denotes | The proto-oncoprotein c-Rel |
| C8 | 235-257 | NP | denotes | nuclear factor kappa B |
| C7 | 231-285 | NP | denotes | the nuclear factor kappa B transcription factor family |
| C9 | 287-292 | NP | denotes | which |
| C10 | 306-309 | NP | denotes | p50 |
| C11 | 330-352 | NP | denotes | nuclear factor kappa B |
| C13 | 372-377 | NP | denotes | c-Rel |
| C14 | 444-447 | NP | denotes | p50 |
| C12 | 372-447 | NP | denotes | c-Rel binds to kappa B sites as homodimers as well as heterodimers with p50 |
| C15 | 449-482 | NP | denotes | These homodimers and heterodimers |
| C17 | 581-590 | NP | denotes | the c-Rel |
| C16 | 581-600 | NP | denotes | the c-Rel homodimer |
| C18 | 625-645 | NP | denotes | interleukin-6 (IL-6) |
| C19 | 693-696 | NP | denotes | its |
| C20 | 714-717 | NP | denotes | p50 |
| C21 | 746-785 | NP | denotes | a lymphoid cell-specific nuclear factor |
| C22 | 794-798 | NP | denotes | that |
| C23 | 808-813 | NP | denotes | c-Rel |
| C24 | 836-847 | NP | denotes | this factor |
| C26 | 856-860 | NP | denotes | IL-6 |
| C25 | 856-886 | NP | denotes | IL-6 kappa B binding factor II |
| C28 | 907-916 | NP | denotes | the c-Rel |
| C27 | 907-926 | NP | denotes | the c-Rel homodimer |
| C30 | 965-969 | NP | denotes | IL-6 |
| C29 | 957-1000 | NP | denotes | several IL-6 kappa B-related kappa B motifs |
| C32 | 1049-1053 | NP | denotes | IL-6 |
| C31 | 1045-1067 | NP | denotes | the IL-6 kappa B motif |
| C33 | 1158-1161 | NP | denotes | its |
| C34 | 1200-1214 | NP | denotes | lymphoid cells |
| C36 | 1275-1279 | NP | denotes | IL-6 |
| C35 | 1275-1305 | NP | denotes | IL-6 kappa B binding factor II |
| C38 | 1344-1348 | NP | denotes | IL-6 |
| C37 | 1344-1379 | NP | denotes | IL-6 kappa B-related kappa B motifs |
| C39 | 1383-1397 | NP | denotes | lymphoid cells |
| R1 | C4 | C2 | coref-relat | whose,interleukin-6 kappa B-related motifs |
| R2 | C9 | C7 | coref-relat | which,the nuclear factor kappa B transcription factor family |
| R3 | C11 | C8 | coref-ident | nuclear factor kappa B,nuclear factor kappa B |
| R4 | C13 | C6 | coref-ident | c-Rel,The proto-oncoprotein c-Rel |
| R5 | C14 | C10 | coref-ident | p50,p50 |
| R6 | C15 | C12 | coref-ident | These homodimers and heterodimers,c-Rel binds to kappa B sites as homodimers as well as heterodimers with p50 |
| R7 | C17 | C13 | coref-ident | the c-Rel,c-Rel |
| R8 | C18 | C3 | coref-ident | interleukin-6 (IL-6),interleukin-6 |
| R9 | C19 | C16 | coref-pron | its,the c-Rel homodimer |
| R10 | C20 | C14 | coref-ident | p50,p50 |
| R11 | C21 | C1 | coref-ident | a lymphoid cell-specific nuclear factor,A lymphoid cell-specific nuclear factor |
| R12 | C22 | C21 | coref-relat | that,a lymphoid cell-specific nuclear factor |
| R13 | C23 | C17 | coref-ident | c-Rel,the c-Rel |
| R14 | C24 | C25 | coref-ident | this factor,IL-6 kappa B binding factor II |
| R15 | C26 | C18 | coref-ident | IL-6,interleukin-6 (IL-6) |
| R16 | C28 | C23 | coref-ident | the c-Rel,c-Rel |
| R17 | C27 | C16 | coref-ident | the c-Rel homodimer,the c-Rel homodimer |
| R18 | C30 | C26 | coref-ident | IL-6,IL-6 |
| R19 | C29 | C2 | coref-ident | several IL-6 kappa B-related kappa B motifs,interleukin-6 kappa B-related motifs |
| R20 | C32 | C30 | coref-ident | IL-6,IL-6 |
| R21 | C31 | C29 | coref-ident | the IL-6 kappa B motif,several IL-6 kappa B-related kappa B motifs |
| R22 | C33 | C31 | coref-pron | its,the IL-6 kappa B motif |
| R23 | C34 | C5 | coref-ident | lymphoid cells,lymphoid cells |
| R24 | C36 | C32 | coref-ident | IL-6,IL-6 |
| R25 | C35 | C25 | coref-ident | IL-6 kappa B binding factor II,IL-6 kappa B binding factor II |
| R26 | C38 | C36 | coref-ident | IL-6,IL-6 |
| R27 | C37 | C31 | coref-ident | IL-6 kappa B-related kappa B motifs,the IL-6 kappa B motif |
| R28 | C39 | C34 | coref-ident | lymphoid cells,lymphoid cells |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 2-39 | protein_molecule | denotes | lymphoid cell-specific nuclear factor |
| T2 | 51-70 | protein_family_or_group | denotes | c-Rel-like proteins |
| T3 | 101-137 | DNA_domain_or_region | denotes | interleukin-6 kappa B-related motifs |
| T4 | 172-186 | cell_type | denotes | lymphoid cells |
| T5 | 192-215 | protein_molecule | denotes | proto-oncoprotein c-Rel |
| T6 | 235-285 | protein_family_or_group | denotes | nuclear factor kappa B transcription factor family |
| T7 | 306-309 | protein_subunit | denotes | p50 |
| T8 | 314-326 | protein_subunit | denotes | p65 subunits |
| T9 | 330-352 | protein_molecule | denotes | nuclear factor kappa B |
| T10 | 372-377 | protein_molecule | denotes | c-Rel |
| T11 | 387-400 | DNA_domain_or_region | denotes | kappa B sites |
| T12 | 404-414 | protein_complex | denotes | homodimers |
| T13 | 426-438 | protein_subunit | denotes | heterodimers |
| T14 | 444-447 | protein_subunit | denotes | p50 |
| T15 | 455-465 | protein_complex | denotes | homodimers |
| T16 | 470-482 | protein_complex | denotes | heterodimers |
| T17 | 550-564 | DNA_domain_or_region | denotes | kappa B motifs |
| T18 | 585-590 | protein_molecule | denotes | c-Rel |
| T19 | 625-638 | DNA_domain_or_region | denotes | interleukin-6 |
| T20 | 640-644 | protein_molecule | denotes | IL-6 |
| T21 | 650-665 | DNA_domain_or_region | denotes | beta interferon |
| T22 | 666-679 | DNA_domain_or_region | denotes | kappa B sites |
| T23 | 714-717 | protein_subunit | denotes | p50 |
| T24 | 748-785 | protein_family_or_group | denotes | lymphoid cell-specific nuclear factor |
| T25 | 808-813 | protein_molecule | denotes | c-Rel |
| T26 | 822-825 | protein_subunit | denotes | p50 |
| T27 | 856-860 | protein_molecule | denotes | IL-6 |
| T28 | 911-916 | protein_molecule | denotes | c-Rel |
| T29 | 965-969 | protein_molecule | denotes | IL-6 |
| T30 | 986-1000 | DNA_domain_or_region | denotes | kappa B motifs |
| T31 | 1049-1053 | protein_molecule | denotes | IL-6 |
| T32 | 1090-1135 | DNA_domain_or_region | denotes | IL-1/tumor necrosis factor-responsive element |
| T33 | 1139-1156 | cell_type | denotes | nonlymphoid cells |
| T34 | 1200-1214 | cell_type | denotes | lymphoid cells |
| T35 | 1225-1243 | cell_line | denotes | Jurkat T-cell line |
| T36 | 1275-1305 | protein_family_or_group | denotes | IL-6 kappa B binding factor II |
| T37 | 1344-1364 | DNA_domain_or_region | denotes | IL-6 kappa B-related |
| T38 | 1365-1379 | DNA_domain_or_region | denotes | kappa B motifs |
| T39 | 1383-1397 | cell_type | denotes | lymphoid cells |