PubMed:135761
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 100-107 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T2 | 276-283 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T3 | 380-387 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T4 | 541-552 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T5 | 563-574 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T6 | 666-673 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T7 | 784-795 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T8 | 861-872 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T9 | 991-1002 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T10 | 1118-1129 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T11 | 1190-1201 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T12 | 1212-1223 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T13 | 1287-1298 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T14 | 1433-1444 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T15 | 1742-1749 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T16 | 1950-1957 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T17 | 2015-2022 | Glycan_Motif | denotes | glucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG |
| T18 | 2114-2125 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T19 | 2136-2147 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T20 | 2387-2398 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 541-552 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T2 | 563-574 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T3 | 784-795 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T4 | 861-872 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T5 | 991-1002 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T6 | 1118-1129 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T7 | 1190-1201 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T8 | 1212-1223 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T9 | 1287-1298 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T10 | 1433-1444 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T11 | 2114-2125 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T12 | 2136-2147 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T13 | 2387-2398 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-87 | Sentence | denotes | Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. |
| T2 | 88-144 | Sentence | denotes | Effect of D-glucose concentration in the culture medium. |
| T3 | 145-368 | Sentence | denotes | Late log cultures of chick embryo vertebral chondrocytes in Dulbecco's Modified Eagle's Medium with 10% fetal calf serum consume D-glucose from the culture medium at a rate of approximately 0.40 mumol per h per 10(6) cells. |
| T4 | 369-509 | Sentence | denotes | When the D-glucose concentration in the medium drops below 1 mumol per ml the glycogen stores are rapidly exhausted, and cell growth ceases. |
| T5 | 510-802 | Sentence | denotes | 35SO4(2)- is incorporated into chondroitin-6-SO4 and chondroitin-4-SO4 at linear rates of 1.2 and 0.4 nmol per h per 10(6) cells, respectively, until the D-glucose level in the medium drops below 1 mumol per ml, but there is always a slight lag in the initial appearance of chondroitin-4-SO4. |
| T6 | 803-1009 | Sentence | denotes | Throughout the period of 35SO4 2- labeling, the amount of chondroitin-6-SO4 that is recovered in the cells exceeds the amount that is recovered in the medium, but the opposite is true for chondroitin-4-SO4. |
| T7 | 1010-1257 | Sentence | denotes | However, when cells prelabeled with 35SO4(2-) are then transferred to a label-free medium, the secretion of chondroitin sulfates proceeds at much slower rates, and the kinetics of chondroitin-6-SO4 and chondroitin-4-SO4 secretion are very similar. |
| T8 | 1258-1485 | Sentence | denotes | In this chase experiment the chondroitin sulfates are recovered quantitatively after a 24-h incubation period, indicating that these embryonic chondrocytes do not degrade the chondroitin sulfates under these culture conditions. |
| T9 | 1486-1608 | Sentence | denotes | The rate of incorporation of counts from D-[14C]glucosamine into mucopolysaccharides and glycoproteins increase with time. |
| T10 | 1609-1784 | Sentence | denotes | This nonlinear rate results from a progressive increase in the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool as the D-glucose in the culture medium is depleted. |
| T11 | 1785-2030 | Sentence | denotes | A linear relationship is demonstrated between the logarithm of the 14C counts per min per nmol of UDP-N-acetylhexosamine and the logarithm of the concentration of D-glucose in the culture medium over a range of 1 to 20 mumol of D-glucose per ml. |
| T12 | 2031-2278 | Sentence | denotes | The relative rates of appearance of counts from 35SO4(2-) and D-[14]glucosamine in chondroitin 4-SO4 and chondroitin-6-SO4 are used to calculate the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool at each stage in the labeling period. |
| T13 | 2279-2434 | Sentence | denotes | The resulting values are then used to calculate the rates of synthesis of the nonsulfated polymers, namely, chondroitin, hyaluronic acid, and glycoprotein. |
| T1 | 0-87 | Sentence | denotes | Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. |
| T2 | 88-144 | Sentence | denotes | Effect of D-glucose concentration in the culture medium. |
| T3 | 145-368 | Sentence | denotes | Late log cultures of chick embryo vertebral chondrocytes in Dulbecco's Modified Eagle's Medium with 10% fetal calf serum consume D-glucose from the culture medium at a rate of approximately 0.40 mumol per h per 10(6) cells. |
| T4 | 369-509 | Sentence | denotes | When the D-glucose concentration in the medium drops below 1 mumol per ml the glycogen stores are rapidly exhausted, and cell growth ceases. |
| T5 | 510-802 | Sentence | denotes | 35SO4(2)- is incorporated into chondroitin-6-SO4 and chondroitin-4-SO4 at linear rates of 1.2 and 0.4 nmol per h per 10(6) cells, respectively, until the D-glucose level in the medium drops below 1 mumol per ml, but there is always a slight lag in the initial appearance of chondroitin-4-SO4. |
| T6 | 803-1009 | Sentence | denotes | Throughout the period of 35SO4 2- labeling, the amount of chondroitin-6-SO4 that is recovered in the cells exceeds the amount that is recovered in the medium, but the opposite is true for chondroitin-4-SO4. |
| T7 | 1010-1257 | Sentence | denotes | However, when cells prelabeled with 35SO4(2-) are then transferred to a label-free medium, the secretion of chondroitin sulfates proceeds at much slower rates, and the kinetics of chondroitin-6-SO4 and chondroitin-4-SO4 secretion are very similar. |
| T8 | 1258-1485 | Sentence | denotes | In this chase experiment the chondroitin sulfates are recovered quantitatively after a 24-h incubation period, indicating that these embryonic chondrocytes do not degrade the chondroitin sulfates under these culture conditions. |
| T9 | 1486-1608 | Sentence | denotes | The rate of incorporation of counts from D-[14C]glucosamine into mucopolysaccharides and glycoproteins increase with time. |
| T10 | 1609-1784 | Sentence | denotes | This nonlinear rate results from a progressive increase in the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool as the D-glucose in the culture medium is depleted. |
| T11 | 1785-2030 | Sentence | denotes | A linear relationship is demonstrated between the logarithm of the 14C counts per min per nmol of UDP-N-acetylhexosamine and the logarithm of the concentration of D-glucose in the culture medium over a range of 1 to 20 mumol of D-glucose per ml. |
| T12 | 2031-2278 | Sentence | denotes | The relative rates of appearance of counts from 35SO4(2-) and D-[14]glucosamine in chondroitin 4-SO4 and chondroitin-6-SO4 are used to calculate the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool at each stage in the labeling period. |
| T13 | 2279-2434 | Sentence | denotes | The resulting values are then used to calculate the rates of synthesis of the nonsulfated polymers, namely, chondroitin, hyaluronic acid, and glycoprotein. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 67-73 | http://purl.obolibrary.org/obo/MAT_0000226 | denotes | embryo |
| T2 | 172-178 | http://purl.obolibrary.org/obo/MAT_0000226 | denotes | embryo |
| T3 | 179-188 | http://purl.obolibrary.org/obo/MAT_0000373 | denotes | vertebral |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 100-107 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T2 | 276-283 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T3 | 380-387 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T4 | 541-552 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T5 | 563-574 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T6 | 666-673 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T7 | 784-795 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T8 | 861-872 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T9 | 991-1002 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T10 | 1118-1129 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T11 | 1190-1201 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T12 | 1212-1223 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T13 | 1287-1298 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T14 | 1433-1444 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T15 | 1742-1749 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T16 | 1950-1957 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T17 | 2015-2022 | https://glytoucan.org/Structures/Glycans/G15021LG | denotes | glucose |
| T18 | 2114-2125 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T19 | 2136-2147 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T20 | 2387-2398 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 67-73 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
| T2 | 172-178 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
| T3 | 179-188 | Body_part | denotes | vertebral | http://purl.obolibrary.org/obo/MAT_0000373 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 541-552 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 563-574 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 784-795 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 861-872 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T5 | 991-1002 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T6 | 1118-1129 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T7 | 1190-1201 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T8 | 1212-1223 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T9 | 1287-1298 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T10 | 1433-1444 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T11 | 2114-2125 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T12 | 2136-2147 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T13 | 2387-2398 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 74-86 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |
| T2 | 189-201 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |
| T3 | 1401-1413 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 541-552 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 563-574 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 784-795 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 861-872 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T5 | 991-1002 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T6 | 1118-1129 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T7 | 1190-1201 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T8 | 1212-1223 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T9 | 1287-1298 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T10 | 1433-1444 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T11 | 2114-2125 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T12 | 2136-2147 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T13 | 2387-2398 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 67-73 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/UBERON_0000922 |
| T2 | 74-86 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
| T3 | 172-178 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/UBERON_0000922 |
| T4 | 189-201 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
| T5 | 1401-1413 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 67-73 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
| T2 | 172-178 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
| T3 | 179-188 | Body_part | denotes | vertebral | http://purl.obolibrary.org/obo/MAT_0000373 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-87 | Sentence | denotes | Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. |
| T2 | 88-144 | Sentence | denotes | Effect of D-glucose concentration in the culture medium. |
| T3 | 145-368 | Sentence | denotes | Late log cultures of chick embryo vertebral chondrocytes in Dulbecco's Modified Eagle's Medium with 10% fetal calf serum consume D-glucose from the culture medium at a rate of approximately 0.40 mumol per h per 10(6) cells. |
| T4 | 369-509 | Sentence | denotes | When the D-glucose concentration in the medium drops below 1 mumol per ml the glycogen stores are rapidly exhausted, and cell growth ceases. |
| T5 | 510-802 | Sentence | denotes | 35SO4(2)- is incorporated into chondroitin-6-SO4 and chondroitin-4-SO4 at linear rates of 1.2 and 0.4 nmol per h per 10(6) cells, respectively, until the D-glucose level in the medium drops below 1 mumol per ml, but there is always a slight lag in the initial appearance of chondroitin-4-SO4. |
| T6 | 803-1009 | Sentence | denotes | Throughout the period of 35SO4 2- labeling, the amount of chondroitin-6-SO4 that is recovered in the cells exceeds the amount that is recovered in the medium, but the opposite is true for chondroitin-4-SO4. |
| T7 | 1010-1257 | Sentence | denotes | However, when cells prelabeled with 35SO4(2-) are then transferred to a label-free medium, the secretion of chondroitin sulfates proceeds at much slower rates, and the kinetics of chondroitin-6-SO4 and chondroitin-4-SO4 secretion are very similar. |
| T8 | 1258-1485 | Sentence | denotes | In this chase experiment the chondroitin sulfates are recovered quantitatively after a 24-h incubation period, indicating that these embryonic chondrocytes do not degrade the chondroitin sulfates under these culture conditions. |
| T9 | 1486-1608 | Sentence | denotes | The rate of incorporation of counts from D-[14C]glucosamine into mucopolysaccharides and glycoproteins increase with time. |
| T10 | 1609-1784 | Sentence | denotes | This nonlinear rate results from a progressive increase in the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool as the D-glucose in the culture medium is depleted. |
| T11 | 1785-2030 | Sentence | denotes | A linear relationship is demonstrated between the logarithm of the 14C counts per min per nmol of UDP-N-acetylhexosamine and the logarithm of the concentration of D-glucose in the culture medium over a range of 1 to 20 mumol of D-glucose per ml. |
| T12 | 2031-2278 | Sentence | denotes | The relative rates of appearance of counts from 35SO4(2-) and D-[14]glucosamine in chondroitin 4-SO4 and chondroitin-6-SO4 are used to calculate the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool at each stage in the labeling period. |
| T13 | 2279-2434 | Sentence | denotes | The resulting values are then used to calculate the rates of synthesis of the nonsulfated polymers, namely, chondroitin, hyaluronic acid, and glycoprotein. |
| T1 | 0-87 | Sentence | denotes | Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. |
| T2 | 88-144 | Sentence | denotes | Effect of D-glucose concentration in the culture medium. |
| T3 | 145-368 | Sentence | denotes | Late log cultures of chick embryo vertebral chondrocytes in Dulbecco's Modified Eagle's Medium with 10% fetal calf serum consume D-glucose from the culture medium at a rate of approximately 0.40 mumol per h per 10(6) cells. |
| T4 | 369-509 | Sentence | denotes | When the D-glucose concentration in the medium drops below 1 mumol per ml the glycogen stores are rapidly exhausted, and cell growth ceases. |
| T5 | 510-802 | Sentence | denotes | 35SO4(2)- is incorporated into chondroitin-6-SO4 and chondroitin-4-SO4 at linear rates of 1.2 and 0.4 nmol per h per 10(6) cells, respectively, until the D-glucose level in the medium drops below 1 mumol per ml, but there is always a slight lag in the initial appearance of chondroitin-4-SO4. |
| T6 | 803-1009 | Sentence | denotes | Throughout the period of 35SO4 2- labeling, the amount of chondroitin-6-SO4 that is recovered in the cells exceeds the amount that is recovered in the medium, but the opposite is true for chondroitin-4-SO4. |
| T7 | 1010-1257 | Sentence | denotes | However, when cells prelabeled with 35SO4(2-) are then transferred to a label-free medium, the secretion of chondroitin sulfates proceeds at much slower rates, and the kinetics of chondroitin-6-SO4 and chondroitin-4-SO4 secretion are very similar. |
| T8 | 1258-1485 | Sentence | denotes | In this chase experiment the chondroitin sulfates are recovered quantitatively after a 24-h incubation period, indicating that these embryonic chondrocytes do not degrade the chondroitin sulfates under these culture conditions. |
| T9 | 1486-1608 | Sentence | denotes | The rate of incorporation of counts from D-[14C]glucosamine into mucopolysaccharides and glycoproteins increase with time. |
| T10 | 1609-1784 | Sentence | denotes | This nonlinear rate results from a progressive increase in the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool as the D-glucose in the culture medium is depleted. |
| T11 | 1785-2030 | Sentence | denotes | A linear relationship is demonstrated between the logarithm of the 14C counts per min per nmol of UDP-N-acetylhexosamine and the logarithm of the concentration of D-glucose in the culture medium over a range of 1 to 20 mumol of D-glucose per ml. |
| T12 | 2031-2278 | Sentence | denotes | The relative rates of appearance of counts from 35SO4(2-) and D-[14]glucosamine in chondroitin 4-SO4 and chondroitin-6-SO4 are used to calculate the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool at each stage in the labeling period. |
| T13 | 2279-2434 | Sentence | denotes | The resulting values are then used to calculate the rates of synthesis of the nonsulfated polymers, namely, chondroitin, hyaluronic acid, and glycoprotein. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-87 | Sentence | denotes | Kinetics of mucopolysaccharide and glycoprotein synthesis by chick embryo chondrocytes. |
| T2 | 88-144 | Sentence | denotes | Effect of D-glucose concentration in the culture medium. |
| T3 | 145-368 | Sentence | denotes | Late log cultures of chick embryo vertebral chondrocytes in Dulbecco's Modified Eagle's Medium with 10% fetal calf serum consume D-glucose from the culture medium at a rate of approximately 0.40 mumol per h per 10(6) cells. |
| T4 | 369-509 | Sentence | denotes | When the D-glucose concentration in the medium drops below 1 mumol per ml the glycogen stores are rapidly exhausted, and cell growth ceases. |
| T5 | 510-802 | Sentence | denotes | 35SO4(2)- is incorporated into chondroitin-6-SO4 and chondroitin-4-SO4 at linear rates of 1.2 and 0.4 nmol per h per 10(6) cells, respectively, until the D-glucose level in the medium drops below 1 mumol per ml, but there is always a slight lag in the initial appearance of chondroitin-4-SO4. |
| T6 | 803-1009 | Sentence | denotes | Throughout the period of 35SO4 2- labeling, the amount of chondroitin-6-SO4 that is recovered in the cells exceeds the amount that is recovered in the medium, but the opposite is true for chondroitin-4-SO4. |
| T7 | 1010-1257 | Sentence | denotes | However, when cells prelabeled with 35SO4(2-) are then transferred to a label-free medium, the secretion of chondroitin sulfates proceeds at much slower rates, and the kinetics of chondroitin-6-SO4 and chondroitin-4-SO4 secretion are very similar. |
| T8 | 1258-1485 | Sentence | denotes | In this chase experiment the chondroitin sulfates are recovered quantitatively after a 24-h incubation period, indicating that these embryonic chondrocytes do not degrade the chondroitin sulfates under these culture conditions. |
| T9 | 1486-1608 | Sentence | denotes | The rate of incorporation of counts from D-[14C]glucosamine into mucopolysaccharides and glycoproteins increase with time. |
| T10 | 1609-1784 | Sentence | denotes | This nonlinear rate results from a progressive increase in the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool as the D-glucose in the culture medium is depleted. |
| T11 | 1785-2030 | Sentence | denotes | A linear relationship is demonstrated between the logarithm of the 14C counts per min per nmol of UDP-N-acetylhexosamine and the logarithm of the concentration of D-glucose in the culture medium over a range of 1 to 20 mumol of D-glucose per ml. |
| T12 | 2031-2278 | Sentence | denotes | The relative rates of appearance of counts from 35SO4(2-) and D-[14]glucosamine in chondroitin 4-SO4 and chondroitin-6-SO4 are used to calculate the specific activity of the UDP-N-acetyl-D-[14C]hexosamine pool at each stage in the labeling period. |
| T13 | 2279-2434 | Sentence | denotes | The resulting values are then used to calculate the rates of synthesis of the nonsulfated polymers, namely, chondroitin, hyaluronic acid, and glycoprotein. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 541-552 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 563-574 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 784-795 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 861-872 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T5 | 991-1002 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T6 | 1118-1129 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T7 | 1190-1201 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T8 | 1212-1223 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T9 | 1287-1298 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T10 | 1433-1444 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T11 | 2114-2125 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T12 | 2136-2147 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T13 | 2387-2398 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 541-552 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 563-574 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 784-795 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 861-872 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T5 | 991-1002 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T6 | 1118-1129 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T7 | 1190-1201 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T8 | 1212-1223 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T9 | 1287-1298 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T10 | 1433-1444 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T11 | 2114-2125 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T12 | 2136-2147 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T13 | 2387-2398 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 67-73 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/UBERON_0000922 |
| T2 | 74-86 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
| T3 | 172-178 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/UBERON_0000922 |
| T4 | 189-201 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
| T5 | 1401-1413 | Body_part | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL_0000138 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 74-86 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |
| T2 | 189-201 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |
| T3 | 1401-1413 | Cell | denotes | chondrocytes | http://purl.obolibrary.org/obo/CL:0000138 |