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PubMed:1353340 JSONTXT

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LitCoin-entities

Id Subject Object Predicate Lexical cue db_id
0 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy MESH:D007966
1 111-126 GeneOrGeneProduct denotes arylsulfatase A NCBIGene:410
2 128-132 GeneOrGeneProduct denotes ARSA NCBIGene:410
3 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy MESH:D007966
4 189-192 DiseaseOrPhenotypicFeature denotes MLD MESH:D007966
5 210-220 SequenceVariant denotes arginine84 DBSNP:rs74315458
6 264-277 GeneOrGeneProduct denotes arylsulfatase NCBIGene:410
7 363-366 DiseaseOrPhenotypicFeature denotes MLD MESH:D007966
8 372-395 SequenceVariant denotes arginine84 to glutamine DBSNP:rs74315458
9 442-446 GeneOrGeneProduct denotes ARSA NCBIGene:410
10 484-488 GeneOrGeneProduct denotes ARSA NCBIGene:410
11 562-570 OrganismTaxon denotes patients NCBITaxon:9606
12 576-579 DiseaseOrPhenotypicFeature denotes MLD MESH:D007966
13 655-659 GeneOrGeneProduct denotes ARSA NCBIGene:410
14 712-715 DiseaseOrPhenotypicFeature denotes MLD MESH:D007966

LitCoin-sentences

Id Subject Object Predicate Lexical cue
T1 0-77 Sentence denotes Late-onset metachromatic leukodystrophy: molecular pathology in two siblings.
T2 78-194 Sentence denotes We report on a new allele at the arylsulfatase A (ARSA) locus causing late-onset metachromatic leukodystrophy (MLD).
T3 195-316 Sentence denotes In that allele arginine84, a residue that is highly conserved in the arylsulfatase gene family, is replaced by glutamine.
T4 317-456 Sentence denotes In contrast to alleles that cause early-onset MLD, the arginine84 to glutamine substitution is associated with some residual ARSA activity.
T5 457-716 Sentence denotes A comparison of genotypes, ARSA activities, and clinical data on 4 individuals carrying the allele of 81 patients with MLD examined, further validates the concept that different degrees of residual ARSA activity are the basis of phenotypical variation in MLD.

LitCoin_Mondo

Id Subject Object Predicate Lexical cue mondo_id
T1 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy 0018868
T2 25-39 DiseaseOrPhenotypicFeature denotes leukodystrophy 0019046
T3 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy 0018868
T4 173-187 DiseaseOrPhenotypicFeature denotes leukodystrophy 0019046

LitCoin-GeneOrGeneProduct-v0

Id Subject Object Predicate Lexical cue
T1 0-4 GeneOrGeneProduct denotes Late
T2 111-126 GeneOrGeneProduct denotes arylsulfatase A
T3 128-132 GeneOrGeneProduct denotes ARSA
T4 148-152 GeneOrGeneProduct denotes late
T5 240-246 GeneOrGeneProduct denotes highly
T6 247-256 GeneOrGeneProduct denotes conserved
T7 264-277 GeneOrGeneProduct denotes arylsulfatase
T8 306-315 GeneOrGeneProduct denotes glutamine
T9 320-328 GeneOrGeneProduct denotes contrast
T10 351-356 GeneOrGeneProduct denotes early
T11 386-395 GeneOrGeneProduct denotes glutamine
T12 442-446 GeneOrGeneProduct denotes ARSA
T13 447-455 GeneOrGeneProduct denotes activity
T14 484-488 GeneOrGeneProduct denotes ARSA
T15 489-499 GeneOrGeneProduct denotes activities
T16 612-619 GeneOrGeneProduct denotes concept
T17 655-659 GeneOrGeneProduct denotes ARSA
T18 660-668 GeneOrGeneProduct denotes activity
T19 677-682 GeneOrGeneProduct denotes basis

LitCoin-GeneOrGeneProduct-v2

Id Subject Object Predicate Lexical cue
T1 111-126 GeneOrGeneProduct denotes arylsulfatase A
T2 128-132 GeneOrGeneProduct denotes ARSA
T3 247-256 GeneOrGeneProduct denotes conserved
T4 264-277 GeneOrGeneProduct denotes arylsulfatase
T5 306-315 GeneOrGeneProduct denotes glutamine
T6 351-356 GeneOrGeneProduct denotes early
T7 386-395 GeneOrGeneProduct denotes glutamine
T8 442-446 GeneOrGeneProduct denotes ARSA
T9 484-488 GeneOrGeneProduct denotes ARSA
T10 655-659 GeneOrGeneProduct denotes ARSA

LitCoin-Disease-MeSH

Id Subject Object Predicate Lexical cue originalLabel
T1 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T2 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T3 189-192 DiseaseOrPhenotypicFeature denotes MLD D007966
T4 363-366 DiseaseOrPhenotypicFeature denotes MLD D007966
T5 576-579 DiseaseOrPhenotypicFeature denotes MLD D007966
T6 712-715 DiseaseOrPhenotypicFeature denotes MLD D007966

LitCoin-GeneOrGeneProduct-v3

Id Subject Object Predicate Lexical cue
T1 111-126 GeneOrGeneProduct denotes arylsulfatase A
T2 128-132 GeneOrGeneProduct denotes ARSA
T3 264-277 GeneOrGeneProduct denotes arylsulfatase
T4 442-446 GeneOrGeneProduct denotes ARSA
T5 484-488 GeneOrGeneProduct denotes ARSA
T6 655-659 GeneOrGeneProduct denotes ARSA

LitCoin_Mondo_095

Id Subject Object Predicate Lexical cue mondo_id
T1 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy 0018868|0009591
T3 128-132 DiseaseOrPhenotypicFeature denotes ARSA 0016828
T4 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy 0018868|0009591
T6 189-192 DiseaseOrPhenotypicFeature denotes MLD 0018868|0009591
T8 363-366 DiseaseOrPhenotypicFeature denotes MLD 0018868|0009591
T10 442-446 DiseaseOrPhenotypicFeature denotes ARSA 0016828
T11 484-488 DiseaseOrPhenotypicFeature denotes ARSA 0016828
T12 576-579 DiseaseOrPhenotypicFeature denotes MLD 0018868|0009591
T14 655-659 DiseaseOrPhenotypicFeature denotes ARSA 0016828
T15 712-715 DiseaseOrPhenotypicFeature denotes MLD 0018868|0009591

LitCoin-NCBITaxon-2

Id Subject Object Predicate Lexical cue
T1 562-570 OrganismTaxon denotes patients

LitCoin-MeSH-Disease-2

Id Subject Object Predicate Lexical cue ID:
T1 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T2 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T3 189-192 DiseaseOrPhenotypicFeature denotes MLD D007966
T4 363-366 DiseaseOrPhenotypicFeature denotes MLD D007966
T5 576-579 DiseaseOrPhenotypicFeature denotes MLD D007966
T6 712-715 DiseaseOrPhenotypicFeature denotes MLD D007966

LitCoin-MONDO_bioort2019

Id Subject Object Predicate Lexical cue #label
T1 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T2 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T3 189-192 DiseaseOrPhenotypicFeature denotes MLD D007966
T4 363-366 DiseaseOrPhenotypicFeature denotes MLD D007966
T5 576-579 DiseaseOrPhenotypicFeature denotes MLD D007966
T6 712-715 DiseaseOrPhenotypicFeature denotes MLD D007966

LitCoin-Chemical-MeSH-CHEBI

Id Subject Object Predicate Lexical cue ID:
T1 111-124 ChemicalEntity denotes arylsulfatase D001192
T2 264-277 ChemicalEntity denotes arylsulfatase D001192
T3 306-315 ChemicalEntity denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T4 386-395 ChemicalEntity denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300

LitCoin-training-merged

Id Subject Object Predicate Lexical cue #label ID:
T4 386-395 ChemicalEntity denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T3 306-315 ChemicalEntity denotes glutamine http://purl.obolibrary.org/obo/CHEBI_28300
T2 264-277 ChemicalEntity denotes arylsulfatase D001192
T1 111-124 ChemicalEntity denotes arylsulfatase D001192
T6 655-659 GeneOrGeneProduct denotes ARSA
T5 484-488 GeneOrGeneProduct denotes ARSA
T93321 442-446 GeneOrGeneProduct denotes ARSA
T34812 264-277 GeneOrGeneProduct denotes arylsulfatase
T946 128-132 GeneOrGeneProduct denotes ARSA
T46637 111-126 GeneOrGeneProduct denotes arylsulfatase A
T3986 712-715 DiseaseOrPhenotypicFeature denotes MLD D007966
T69071 576-579 DiseaseOrPhenotypicFeature denotes MLD D007966
T67418 363-366 DiseaseOrPhenotypicFeature denotes MLD D007966
T56010 189-192 DiseaseOrPhenotypicFeature denotes MLD D007966
T87689 159-187 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T72183 11-39 DiseaseOrPhenotypicFeature denotes metachromatic leukodystrophy D007966
T21888 562-570 OrganismTaxon denotes patients

DisGeNET5_variant_disease

Id Subject Object Predicate Lexical cue
1353340-3#55#78#geners769892461 372-395 geners769892461 denotes arginine84 to glutamine
1353340-3#46#49#diseaseC0023522 363-366 diseaseC0023522 denotes MLD
55#78#geners76989246146#49#diseaseC0023522 1353340-3#55#78#geners769892461 1353340-3#46#49#diseaseC0023522 associated_with arginine84 to glutamine,MLD

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
1353340-4#27#31#gene410 484-488 gene410 denotes ARSA
1353340-4#198#202#gene410 655-659 gene410 denotes ARSA
1353340-4#119#122#diseaseC0023522 576-579 diseaseC0023522 denotes MLD
1353340-4#255#258#diseaseC0023522 712-715 diseaseC0023522 denotes MLD
27#31#gene410119#122#diseaseC0023522 1353340-4#27#31#gene410 1353340-4#119#122#diseaseC0023522 associated_with ARSA,MLD
27#31#gene410255#258#diseaseC0023522 1353340-4#27#31#gene410 1353340-4#255#258#diseaseC0023522 associated_with ARSA,MLD
198#202#gene410119#122#diseaseC0023522 1353340-4#198#202#gene410 1353340-4#119#122#diseaseC0023522 associated_with ARSA,MLD
198#202#gene410255#258#diseaseC0023522 1353340-4#198#202#gene410 1353340-4#255#258#diseaseC0023522 associated_with ARSA,MLD

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 25-39 HP:0002415 denotes leukodystrophy
AB1 173-187 HP:0002415 denotes leukodystrophy

PubCasesORDO

Id Subject Object Predicate Lexical cue
TI1 11-39 ORDO:512 denotes metachromatic leukodystrophy
AB1 159-187 ORDO:512 denotes metachromatic leukodystrophy
AB2 189-192 ORDO:512 denotes MLD
AB3 363-366 ORDO:512 denotes MLD
AB4 576-579 ORDO:512 denotes MLD
AB5 712-715 ORDO:512 denotes MLD

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-77 Sentence denotes Late-onset metachromatic leukodystrophy: molecular pathology in two siblings.
TextSentencer_T2 78-194 Sentence denotes We report on a new allele at the arylsulfatase A (ARSA) locus causing late-onset metachromatic leukodystrophy (MLD).
TextSentencer_T3 195-316 Sentence denotes In that allele arginine84, a residue that is highly conserved in the arylsulfatase gene family, is replaced by glutamine.
TextSentencer_T4 317-456 Sentence denotes In contrast to alleles that cause early-onset MLD, the arginine84 to glutamine substitution is associated with some residual ARSA activity.
TextSentencer_T5 457-716 Sentence denotes A comparison of genotypes, ARSA activities, and clinical data on 4 individuals carrying the allele of 81 patients with MLD examined, further validates the concept that different degrees of residual ARSA activity are the basis of phenotypical variation in MLD.
T1 0-77 Sentence denotes Late-onset metachromatic leukodystrophy: molecular pathology in two siblings.
T2 78-194 Sentence denotes We report on a new allele at the arylsulfatase A (ARSA) locus causing late-onset metachromatic leukodystrophy (MLD).
T3 195-316 Sentence denotes In that allele arginine84, a residue that is highly conserved in the arylsulfatase gene family, is replaced by glutamine.
T4 317-456 Sentence denotes In contrast to alleles that cause early-onset MLD, the arginine84 to glutamine substitution is associated with some residual ARSA activity.
T5 457-716 Sentence denotes A comparison of genotypes, ARSA activities, and clinical data on 4 individuals carrying the allele of 81 patients with MLD examined, further validates the concept that different degrees of residual ARSA activity are the basis of phenotypical variation in MLD.

NCBIDiseaseCorpus

Id Subject Object Predicate Lexical cue
T1 11-39 SpecificDisease:D007966 denotes metachromatic leukodystrophy
T2 159-187 SpecificDisease:D007966 denotes metachromatic leukodystrophy
T3 189-192 SpecificDisease:D007966 denotes MLD
T4 363-366 SpecificDisease:D007966 denotes MLD
T5 576-579 Modifier:D007966 denotes MLD
T6 712-715 SpecificDisease:D007966 denotes MLD

DisGeNET

Id Subject Object Predicate Lexical cue
T0 128-132 gene:410 denotes ARSA
T1 189-192 disease:C0023522 denotes MLD
T2 128-132 gene:410 denotes ARSA
T3 159-187 disease:C0023522 denotes metachromatic leukodystrophy
T4 111-126 gene:410 denotes arylsulfatase A
T5 189-192 disease:C0023522 denotes MLD
T6 111-126 gene:410 denotes arylsulfatase A
T7 159-187 disease:C0023522 denotes metachromatic leukodystrophy
T8 655-659 gene:410 denotes ARSA
T9 712-715 disease:C0023522 denotes MLD
T10 484-488 gene:410 denotes ARSA
T11 712-715 disease:C0023522 denotes MLD
T12 484-488 gene:410 denotes ARSA
T13 576-579 disease:C0023522 denotes MLD
R1 T0 T1 associated_with ARSA,MLD
R2 T2 T3 associated_with ARSA,metachromatic leukodystrophy
R3 T4 T5 associated_with arylsulfatase A,MLD
R4 T6 T7 associated_with arylsulfatase A,metachromatic leukodystrophy
R5 T8 T9 associated_with ARSA,MLD
R6 T10 T11 associated_with ARSA,MLD
R7 T12 T13 associated_with ARSA,MLD

NCBI-Disease-Train

Id Subject Object Predicate Lexical cue database_id
T740 11-39 SpecificDisease denotes metachromatic leukodystrophy D007966
T741 159-187 SpecificDisease denotes metachromatic leukodystrophy D007966
T742 189-192 SpecificDisease denotes MLD D007966
T743 363-366 SpecificDisease denotes MLD D007966
T744 576-579 Modifier denotes MLD D007966
T745 712-715 SpecificDisease denotes MLD D007966

NCBI-Disease-Corpus-All

Id Subject Object Predicate Lexical cue database_id
T740 11-39 SpecificDisease denotes metachromatic leukodystrophy D007966
T741 159-187 SpecificDisease denotes metachromatic leukodystrophy D007966
T742 189-192 SpecificDisease denotes MLD D007966
T743 363-366 SpecificDisease denotes MLD D007966
T744 576-579 Modifier denotes MLD D007966
T745 712-715 SpecificDisease denotes MLD D007966

NCBI-Disease-Corpus-2stage-All

Id Subject Object Predicate Lexical cue
T1 11-39 SpecificDisease denotes metachromatic leukodystrophy
T2 159-187 SpecificDisease denotes metachromatic leukodystrophy
T3 189-192 SpecificDisease denotes MLD
T4 363-366 SpecificDisease denotes MLD
T5 576-579 SpecificDisease denotes MLD
T6 712-715 SpecificDisease denotes MLD

NCBI-Disease-Corpus-rezarta-All

Id Subject Object Predicate Lexical cue
T1 11-39 SpecificDisease denotes metachromatic leukodystrophy
T2 159-187 SpecificDisease denotes metachromatic leukodystrophy
T3 189-192 SpecificDisease denotes MLD
T4 363-366 SpecificDisease denotes MLD
T5 576-579 SpecificDisease denotes MLD
T6 712-715 SpecificDisease denotes MLD

NCBI-Disease-Corpus-4oGuideline-All

Id Subject Object Predicate Lexical cue
T1 11-39 SpecificDisease denotes metachromatic leukodystrophy
T2 159-187 SpecificDisease denotes metachromatic leukodystrophy
T3 189-192 SpecificDisease denotes MLD
T4 363-366 SpecificDisease denotes MLD
T5 576-579 SpecificDisease denotes MLD
T6 712-715 SpecificDisease denotes MLD

NCBI-Disease-Corpus-Simple-All

Id Subject Object Predicate Lexical cue
T1 0-39 SpecificDisease denotes Late-onset metachromatic leukodystrophy
T2 148-193 SpecificDisease denotes late-onset metachromatic leukodystrophy (MLD)
T3 351-362 Modifier denotes early-onset
T4 363-366 SpecificDisease denotes MLD
T5 576-579 SpecificDisease denotes MLD
T6 712-715 SpecificDisease denotes MLD