> top > docs > PubMed:1347914 > annotations

PubMed:1347914 JSONTXT

Annnotations TAB JSON ListView MergeView

jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 85-108 protein denotes retinoic acid receptors
T2 132-147 DNA denotes v-erbA oncogene
T3 160-175 DNA denotes v-erbA oncogene
T4 202-232 protein denotes thyroid hormone receptor alpha
T5 234-249 protein denotes c-erbA/TR-alpha
T6 341-358 DNA denotes erythrocyte genes
T7 396-417 DNA denotes proto-oncogene c-erbA
T8 477-507 protein denotes thyroid hormone receptor alpha
T9 509-524 protein denotes c-erbA/TR-alpha
T10 550-578 protein denotes retinoic acid receptor alpha
T11 580-589 protein denotes RAR-alpha
T12 739-767 cell_type denotes normal erythroid progenitors
T13 826-850 DNA denotes tyrosine kinase oncogene
T14 876-890 cell_type denotes immature cells
T15 935-947 cell_type denotes mature cells
T16 1206-1221 protein denotes human RAR-alpha
T17 1225-1256 cell_line denotes receptor-negative erythroblasts
T18 1325-1343 cell_type denotes unresponsive cells
T19 1367-1376 protein denotes RAR-alpha
T20 1442-1467 protein denotes exogenous c-erbA/TR-alpha
T21 1471-1484 cell_type denotes erythroblasts

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-155 Sentence denotes Modulation of normal erythroid differentiation by the endogenous thyroid hormone and retinoic acid receptors: a possible target for v-erbA oncogene action.
S2 156-436 Sentence denotes The v-erbA oncogene, a mutated version of the thyroid hormone receptor alpha (c-erbA/TR-alpha), inhibits erythroid differentiation and constitutively represses transcription of certain erythrocyte genes, suggesting a normal function of the proto-oncogene c-erbA in erythropoiesis.
S3 437-657 Sentence denotes Here we demonstrate that the endogenous thyroid hormone receptor alpha (c-erbA/TR-alpha) and the closely related retinoic acid receptor alpha (RAR-alpha) play a role in the regulation of normal erythroid differentiation.
S4 658-851 Sentence denotes Retinoic acid (RA) distinctly modulated the erythroid differentiation program of normal erythroid progenitors and erythroblasts reversibly transformed by a conditional tyrosine kinase oncogene.
S5 852-979 Sentence denotes When added pulsewise to immature cells, differentiation was accelerated while more mature cells underwent premature cell death.
S6 980-1041 Sentence denotes Thyroid hormone (T3) alone caused similar but weaker effects.
S7 1042-1187 Sentence denotes Interestingly, T3 strongly enhanced the action of RA, suggesting cooperative action of the two receptors in modulating erythroid differentiation.
S8 1188-1408 Sentence denotes Expression of the human RAR-alpha in receptor-negative erythroblasts conferred RA-induced regulation of differentiation to the otherwise unresponsive cells, thus showing that the RAR-alpha is essential for the RA effect.
S9 1409-1599 Sentence denotes Likewise, enhanced expression of exogenous c-erbA/TR-alpha in erythroblasts rendered them susceptible to modulation of differentiation by T3, suggesting a similar function of both receptors.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 14-46 NP denotes normal erythroid differentiation
C3 65-80 NP denotes thyroid hormone
C5 85-98 NP denotes retinoic acid
C4 85-108 NP denotes retinoic acid receptors
C2 50-108 NP denotes the endogenous thyroid hormone and retinoic acid receptors
C6 132-147 NP denotes v-erbA oncogene
C7 156-175 NP denotes The v-erbA oncogene
C10 202-217 NP denotes thyroid hormone
C11 234-240 NP denotes c-erbA
C9 198-250 NP denotes the thyroid hormone receptor alpha (c-erbA/TR-alpha)
C8 177-250 NP denotes a mutated version of the thyroid hormone receptor alpha (c-erbA/TR-alpha)
C12 261-286 NP denotes erythroid differentiation
C13 392-417 NP denotes the proto-oncogene c-erbA
C15 477-492 NP denotes thyroid hormone
C16 509-515 NP denotes c-erbA
C14 462-525 NP denotes the endogenous thyroid hormone receptor alpha (c-erbA/TR-alpha)
C19 550-563 NP denotes retinoic acid
C18 550-572 NP denotes retinoic acid receptor
C17 550-590 NP denotes retinoic acid receptor alpha (RAR-alpha)
C20 624-656 NP denotes normal erythroid differentiation
C21 658-676 NP denotes Retinoic acid (RA)
C22 772-785 NP denotes erythroblasts
C23 980-1000 NP denotes Thyroid hormone (T3)
C24 1057-1059 NP denotes T3
C25 1092-1094 NP denotes RA
C26 1129-1146 NP denotes the two receptors
C27 1161-1186 NP denotes erythroid differentiation
C28 1202-1221 NP denotes the human RAR-alpha
C29 1225-1256 NP denotes receptor-negative erythroblasts
C30 1363-1376 NP denotes the RAR-alpha
C32 1452-1458 NP denotes c-erbA
C31 1442-1467 NP denotes exogenous c-erbA/TR-alpha
C33 1471-1484 NP denotes erythroblasts
C34 1494-1498 NP denotes them
C35 1547-1549 NP denotes T3
C36 1584-1598 NP denotes both receptors
R1 C7 C6 coref-ident The v-erbA oncogene,v-erbA oncogene
R2 C10 C3 coref-ident thyroid hormone,thyroid hormone
R3 C8 C7 coref-appos a mutated version of the thyroid hormone receptor alpha (c-erbA/TR-alpha),The v-erbA oncogene
R4 C12 C1 coref-ident erythroid differentiation,normal erythroid differentiation
R5 C13 C11 coref-ident the proto-oncogene c-erbA,c-erbA
R6 C15 C10 coref-ident thyroid hormone,thyroid hormone
R7 C16 C13 coref-ident c-erbA,the proto-oncogene c-erbA
R8 C14 C9 coref-ident the endogenous thyroid hormone receptor alpha (c-erbA/TR-alpha),the thyroid hormone receptor alpha (c-erbA/TR-alpha)
R9 C19 C5 coref-ident retinoic acid,retinoic acid
R10 C18 C4 coref-ident retinoic acid receptor,retinoic acid receptors
R11 C20 C12 coref-ident normal erythroid differentiation,erythroid differentiation
R12 C21 C19 coref-ident Retinoic acid (RA),retinoic acid
R13 C23 C15 coref-ident Thyroid hormone (T3),thyroid hormone
R14 C24 C23 coref-ident T3,Thyroid hormone (T3)
R15 C25 C21 coref-ident RA,Retinoic acid (RA)
R16 C26 C2 coref-ident the two receptors,the endogenous thyroid hormone and retinoic acid receptors
R17 C27 C20 coref-ident erythroid differentiation,normal erythroid differentiation
R18 C28 C17 coref-other the human RAR-alpha,retinoic acid receptor alpha (RAR-alpha)
R19 C29 C22 coref-other receptor-negative erythroblasts,erythroblasts
R20 C30 C17 coref-ident the RAR-alpha,retinoic acid receptor alpha (RAR-alpha)
R21 C32 C16 coref-ident c-erbA,c-erbA
R22 C31 C14 coref-ident exogenous c-erbA/TR-alpha,the endogenous thyroid hormone receptor alpha (c-erbA/TR-alpha)
R23 C33 C22 coref-ident erythroblasts,erythroblasts
R24 C34 C33 coref-pron them,erythroblasts
R25 C35 C24 coref-ident T3,T3
R26 C36 C26 coref-ident both receptors,the two receptors

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 14-46 other_name denotes normal erythroid differentiation
T2 54-80 other_organic_compound denotes endogenous thyroid hormone
T3 85-108 protein_molecule denotes retinoic acid receptors
T4 132-147 DNA_molecule denotes v-erbA oncogene
T5 160-175 DNA_molecule denotes v-erbA oncogene
T6 202-232 protein_molecule denotes thyroid hormone receptor alpha
T7 234-249 protein_molecule denotes c-erbA/TR-alpha
T8 261-286 other_name denotes erythroid differentiation
T9 341-358 DNA_family_or_group denotes erythrocyte genes
T10 396-417 DNA_domain_or_region denotes proto-oncogene c-erbA
T11 421-435 other_name denotes erythropoiesis
T12 477-507 protein_molecule denotes thyroid hormone receptor alpha
T13 509-524 protein_molecule denotes c-erbA/TR-alpha
T14 550-578 protein_molecule denotes retinoic acid receptor alpha
T15 580-589 protein_molecule denotes RAR-alpha
T16 624-656 other_name denotes normal erythroid differentiation
T17 658-671 other_organic_compound denotes Retinoic acid
T18 673-675 other_organic_compound denotes RA
T19 702-735 other_name denotes erythroid differentiation program
T20 739-767 cell_type denotes normal erythroid progenitors
T21 826-850 DNA_domain_or_region denotes tyrosine kinase oncogene
T22 876-890 cell_type denotes immature cells
T23 935-947 cell_type denotes mature cells
T24 958-978 other_name denotes premature cell death
T25 980-995 other_organic_compound denotes Thyroid hormone
T26 997-999 other_organic_compound denotes T3
T27 1057-1059 other_organic_compound denotes T3
T28 1092-1094 other_organic_compound denotes RA
T29 1161-1186 other_name denotes erythroid differentiation
T30 1206-1211 protein_molecule denotes human
T31 1212-1221 protein_molecule denotes RAR-alpha
T32 1225-1256 cell_line denotes receptor-negative erythroblasts
T33 1267-1269 other_organic_compound denotes RA
T34 1325-1343 cell_type denotes unresponsive cells
T35 1367-1376 protein_molecule denotes RAR-alpha
T36 1398-1407 other_name denotes RA effect
T37 1442-1451 protein_molecule denotes exogenous
T38 1452-1467 protein_molecule denotes c-erbA/TR-alpha
T39 1471-1484 cell_type denotes erythroblasts
T40 1547-1549 other_organic_compound denotes T3