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PubMed:12975617 JSONTXT

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Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 23-38 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T2 618-633 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-67 Sentence denotes Developmental roles of heparan sulfate proteoglycans in Drosophila.
TextSentencer_T2 68-177 Sentence denotes The formation of complex patterns in multi-cellular organisms is regulated by a number of signaling pathways.
TextSentencer_T3 178-299 Sentence denotes In particular, the Wnt and Hedgehog (Hh) pathways have been identified as critical organizers of pattern in many tissues.
TextSentencer_T4 300-568 Sentence denotes Although extensive biochemical and genetic studies have elucidated the central components of the signal transduction pathways regulated by these secreted molecules, we still do not understand fully how they organize gradients of gene activities through field of cells.
TextSentencer_T5 569-731 Sentence denotes Studies in Drosophila have implicated a role for heparan sulfate proteoglycans (HSPGs) in regulating the signaling activities and distribution of both Wnt and Hh.
TextSentencer_T6 732-856 Sentence denotes Here we review these findings and discuss various models by which HSPGs regulate the distributions of Wnt and Hh morphogens.
T1 0-67 Sentence denotes Developmental roles of heparan sulfate proteoglycans in Drosophila.
T2 68-177 Sentence denotes The formation of complex patterns in multi-cellular organisms is regulated by a number of signaling pathways.
T3 178-299 Sentence denotes In particular, the Wnt and Hedgehog (Hh) pathways have been identified as critical organizers of pattern in many tissues.
T4 300-568 Sentence denotes Although extensive biochemical and genetic studies have elucidated the central components of the signal transduction pathways regulated by these secreted molecules, we still do not understand fully how they organize gradients of gene activities through field of cells.
T5 569-731 Sentence denotes Studies in Drosophila have implicated a role for heparan sulfate proteoglycans (HSPGs) in regulating the signaling activities and distribution of both Wnt and Hh.
T6 732-856 Sentence denotes Here we review these findings and discuss various models by which HSPGs regulate the distributions of Wnt and Hh morphogens.

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 56-66 OrganismTaxon denotes Drosophila 2081351|32281|7215
T4 111-129 OrganismTaxon denotes cellular organisms 131567
T5 580-590 OrganismTaxon denotes Drosophila 2081351|32281|7215

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 105-129 Body_part denotes multi-cellular organisms http://purl.obolibrary.org/obo/UBERON_0000468
T2 261-271 Body_part denotes organizers http://purl.obolibrary.org/obo/UBERON_0003062|http://purl.obolibrary.org/obo/UBERON_3010449|http://purl.obolibrary.org/obo/UBERON_3010457
T5 507-515 Body_part denotes organize http://purl.obolibrary.org/obo/UBERON_0003062|http://purl.obolibrary.org/obo/UBERON_3010449|http://purl.obolibrary.org/obo/UBERON_3010457