PubMed:12975608
Annnotations
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 77-92 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | Heparan sulfate |
| T2 | 370-385 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1037-1043 | http://purl.obolibrary.org/obo/MAT_0000226 | denotes | embryo |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T1 | 0-76 | Sentence | denotes | Unlocking the secrets of syndecans: transgenic organisms as a potential key. |
| TextSentencer_T2 | 77-268 | Sentence | denotes | Heparan sulfate proteoglycans are known to modulate the activity of a large number of extracellular ligands thereby having the potential to regulate a great diversity of biological processes. |
| TextSentencer_T3 | 269-408 | Sentence | denotes | The long-term studies in our laboratory have focused on the syndecans, one of the major cell surface heparan sulfate proteoglycan families. |
| TextSentencer_T4 | 409-550 | Sentence | denotes | Most early work on syndecans involved biochemical studies that provided initial information on their structure and putative biological roles. |
| TextSentencer_T5 | 551-671 | Sentence | denotes | In recent years, the development of transgenic organisms has allowed a more complete understanding of syndecan function. |
| TextSentencer_T6 | 672-816 | Sentence | denotes | Studies with transgenic syndecan-1 and syndecan-3 mice have demonstrated an unforeseen role for syndecans in the regulation of feeding behavior. |
| TextSentencer_T7 | 817-936 | Sentence | denotes | Syndecan-1 knockout mice display a reduced susceptibility to both Wnt-induced tumorigenesis and microbial pathogenesis. |
| TextSentencer_T8 | 937-1110 | Sentence | denotes | Experiments with Drosophila show that syndecan is first expressed upon cellularization in the early embryo, and may play a role in the early developmental stages of the fly. |
| TextSentencer_T9 | 1111-1263 | Sentence | denotes | This review focuses on these diverse functions of the syndecans that have been elucidated by the use of transgenic mice and Drosophila as model systems. |
| T1 | 0-76 | Sentence | denotes | Unlocking the secrets of syndecans: transgenic organisms as a potential key. |
| T2 | 77-268 | Sentence | denotes | Heparan sulfate proteoglycans are known to modulate the activity of a large number of extracellular ligands thereby having the potential to regulate a great diversity of biological processes. |
| T3 | 269-408 | Sentence | denotes | The long-term studies in our laboratory have focused on the syndecans, one of the major cell surface heparan sulfate proteoglycan families. |
| T4 | 409-550 | Sentence | denotes | Most early work on syndecans involved biochemical studies that provided initial information on their structure and putative biological roles. |
| T5 | 551-671 | Sentence | denotes | In recent years, the development of transgenic organisms has allowed a more complete understanding of syndecan function. |
| T6 | 672-816 | Sentence | denotes | Studies with transgenic syndecan-1 and syndecan-3 mice have demonstrated an unforeseen role for syndecans in the regulation of feeding behavior. |
| T7 | 817-936 | Sentence | denotes | Syndecan-1 knockout mice display a reduced susceptibility to both Wnt-induced tumorigenesis and microbial pathogenesis. |
| T8 | 937-1110 | Sentence | denotes | Experiments with Drosophila show that syndecan is first expressed upon cellularization in the early embryo, and may play a role in the early developmental stages of the fly. |
| T9 | 1111-1263 | Sentence | denotes | This review focuses on these diverse functions of the syndecans that have been elucidated by the use of transgenic mice and Drosophila as model systems. |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 817-827 | gene:6382 | denotes | Syndecan-1 |
| T1 | 895-908 | disease:C0596263 | denotes | tumorigenesis |
| R1 | T0 | T1 | associated_with | Syndecan-1,tumorigenesis |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1037-1043 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-76 | Sentence | denotes | Unlocking the secrets of syndecans: transgenic organisms as a potential key. |
| T2 | 77-268 | Sentence | denotes | Heparan sulfate proteoglycans are known to modulate the activity of a large number of extracellular ligands thereby having the potential to regulate a great diversity of biological processes. |
| T3 | 269-408 | Sentence | denotes | The long-term studies in our laboratory have focused on the syndecans, one of the major cell surface heparan sulfate proteoglycan families. |
| T4 | 409-550 | Sentence | denotes | Most early work on syndecans involved biochemical studies that provided initial information on their structure and putative biological roles. |
| T5 | 551-671 | Sentence | denotes | In recent years, the development of transgenic organisms has allowed a more complete understanding of syndecan function. |
| T6 | 672-816 | Sentence | denotes | Studies with transgenic syndecan-1 and syndecan-3 mice have demonstrated an unforeseen role for syndecans in the regulation of feeding behavior. |
| T7 | 817-936 | Sentence | denotes | Syndecan-1 knockout mice display a reduced susceptibility to both Wnt-induced tumorigenesis and microbial pathogenesis. |
| T8 | 937-1110 | Sentence | denotes | Experiments with Drosophila show that syndecan is first expressed upon cellularization in the early embryo, and may play a role in the early developmental stages of the fly. |
| T9 | 1111-1263 | Sentence | denotes | This review focuses on these diverse functions of the syndecans that have been elucidated by the use of transgenic mice and Drosophila as model systems. |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 722-726 | Organism | denotes | mice | 10088 |
| T2 | 837-841 | Organism | denotes | mice | 10088 |
| T3 | 954-964 | Organism | denotes | Drosophila | 2081351|32281|7215 |
| T6 | 1226-1230 | Organism | denotes | mice | 10088 |
| T7 | 1235-1245 | Organism | denotes | Drosophila | 2081351|32281|7215 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 77-92 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | Heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
| T2 | 370-385 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 47-56 | Body_part | denotes | organisms | http://purl.obolibrary.org/obo/UBERON_0000468 |
| T2 | 163-176 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T3 | 598-607 | Body_part | denotes | organisms | http://purl.obolibrary.org/obo/UBERON_0000468 |
| T4 | 1031-1043 | Body_part | denotes | early embryo | http://purl.obolibrary.org/obo/UBERON_0019248 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 357-369 | Body_part | denotes | cell surface | FMA:67653 |
| T2 | 1037-1043 | Body_part | denotes | embryo | FMA:296970 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1037-1043 | Body_part | denotes | embryo | http://purl.obolibrary.org/obo/MAT_0000226 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 722-726 | OrganismTaxon | denotes | mice | 10088 |
| T2 | 837-841 | OrganismTaxon | denotes | mice | 10088 |
| T3 | 954-964 | OrganismTaxon | denotes | Drosophila | 2081351|32281|7215 |
| T6 | 1226-1230 | OrganismTaxon | denotes | mice | 10088 |
| T7 | 1235-1245 | OrganismTaxon | denotes | Drosophila | 2081351|32281|7215 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 47-56 | Body_part | denotes | organisms | http://purl.obolibrary.org/obo/UBERON_0000468 |
| T2 | 163-176 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
| T3 | 598-607 | Body_part | denotes | organisms | http://purl.obolibrary.org/obo/UBERON_0000468 |
| T4 | 1031-1043 | Body_part | denotes | early embryo | http://purl.obolibrary.org/obo/UBERON_0019248 |