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PubMed:12966086 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 516-527 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT

sentences

Id Subject Object Predicate Lexical cue
T1 0-201 Sentence denotes Molecular cloning and characterization of a novel human beta 1,4-N-acetylgalactosaminyltransferase, beta 4GalNAc-T3, responsible for the synthesis of N,N'-diacetyllactosediamine, galNAc beta 1-4GlcNAc.
T2 202-436 Sentence denotes We found a novel human glycosyltransferase gene carrying a hypothetical beta1,4-glycosyltransferase motif during a BLAST search, and we cloned its full-length open reading frame by using the 5'-rapid amplification of cDNA ends method.
T3 437-606 Sentence denotes It encodes a type II transmembrane protein of 999 amino acids with homology to chondroitin sulfate synthase in its C-terminal region (GenBank accession number AB089940).
T4 607-689 Sentence denotes Its putative orthologous gene was also found in mouse (accession number AB114826).
T5 690-781 Sentence denotes The truncated form of the human enzyme was expressed in HEK293T cells as a soluble protein.
T6 782-846 Sentence denotes The recombinant enzyme transferred GalNAc to GlcNAc beta-benzyl.
T7 847-959 Sentence denotes The product was deduced to be GalNAc beta 1-4GlcNAc beta-benzyl based on mass spectrometry and NMR spectroscopy.
T8 960-1242 Sentence denotes We renamed the enzyme beta1,4-N-acetylgalactosaminyltransferase-III (beta 4GalNAc-T3). beta 4GalNAc-T3 effectively synthesized N,N'-diacetylgalactosediamine, GalNAc beta 1-4GlcNAc, at non-reducing termini of various acceptors derived not only from N-glycans but also from O-glycans.
T9 1243-1357 Sentence denotes Quantitative real time PCR analysis showed that its transcript was highly expressed in stomach, colon, and testis.
T10 1358-1579 Sentence denotes As some glycohormones contain N,N'-diacetylgalactosediamine structures in their N-glycans, we examined the ability of beta 4GalNAc-T3 to synthesize N,N'-diacetylgalactosediamine structures in N-glycans on a model protein.
T11 1580-1734 Sentence denotes When fetal calf fetuin treated with neuraminidase and beta1,4-galactosidase was utilized as an acceptor protein, beta 4GalNAc-T3 transferred GalNAc to it.
T12 1735-1834 Sentence denotes Furthermore, the majority of the signal from GalNAc disappeared on treatment with glycopeptidase F.
T13 1835-2021 Sentence denotes These results suggest that beta 4GalNAc-T3 could transfer GalNAc residues, producing N,N'-diacetylgalactosediamine structures at least in N-glycans and probably in both N- and O-glycans.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 516-527 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1330-1337 http://purl.obolibrary.org/obo/MAT_0000051 denotes stomach
T2 1339-1344 http://purl.obolibrary.org/obo/MAT_0000526 denotes colon
T3 1350-1356 http://purl.obolibrary.org/obo/MAT_0000132 denotes testis

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 516-527 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 179-185 Glycan denotes galNAc
T2 516-527 Glycan denotes chondroitin
T3 817-823 Glycan denotes GalNAc
T4 877-883 Glycan denotes GalNAc
T5 1118-1124 Glycan denotes GalNAc
T6 1721-1727 Glycan denotes GalNAc
T7 1780-1786 Glycan denotes GalNAc
T8 1893-1899 Glycan denotes GalNAc

glycogenes

Id Subject Object Predicate Lexical cue
PD-GlycoGenes20190927-B_T1 56-98 https://acgg.asia/db/ggdb/info/gg107 denotes beta 1,4-N-acetylgalactosaminyltransferase
PD-GlycoGenes20190927-B_T2 56-98 https://acgg.asia/db/ggdb/info/gg106 denotes beta 1,4-N-acetylgalactosaminyltransferase
PD-GlycoGenes20190927-B_T3 56-98 https://acgg.asia/db/ggdb/info/gg105 denotes beta 1,4-N-acetylgalactosaminyltransferase
PD-GlycoGenes20190927-B_T4 455-457 https://acgg.asia/db/ggdb/info/gg111 denotes II
PD-GlycoGenes20190927-B_T5 982-1023 https://acgg.asia/db/ggdb/info/gg107 denotes beta1,4-N-acetylgalactosaminyltransferase
PD-GlycoGenes20190927-B_T6 982-1023 https://acgg.asia/db/ggdb/info/gg106 denotes beta1,4-N-acetylgalactosaminyltransferase
PD-GlycoGenes20190927-B_T7 982-1023 https://acgg.asia/db/ggdb/info/gg105 denotes beta1,4-N-acetylgalactosaminyltransferase

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 827-833 chem:24139 denotes GlcNAc

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1330-1337 Body_part denotes stomach http://purl.obolibrary.org/obo/MAT_0000051
T2 1339-1344 Body_part denotes colon http://purl.obolibrary.org/obo/MAT_0000526
T3 1350-1356 Body_part denotes testis http://purl.obolibrary.org/obo/MAT_0000132

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 50-55 OrganismTaxon denotes human 9606
T2 219-224 OrganismTaxon denotes human 9606
T3 655-660 OrganismTaxon denotes mouse 10088|10090
T5 716-721 OrganismTaxon denotes human 9606

Glycosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 516-527 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 458-471 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T2 1330-1337 Body_part denotes stomach http://purl.obolibrary.org/obo/UBERON_0000945
T3 1339-1344 Body_part denotes colon http://purl.obolibrary.org/obo/UBERON_0001155
T4 1350-1356 Body_part denotes testis http://purl.obolibrary.org/obo/UBERON_0000473