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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 819-834 Glycan_Motif denotes keratan sulfate https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82109MW
T2 1433-1444 Glycan_Motif denotes Chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T3 1652-1673 Glycan_Motif denotes N-acetylgalactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB
T4 1710-1720 Glycan_Motif denotes Hyaluronan https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00017MO
T5 1793-1808 Glycan_Motif denotes Keratan sulfate https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82109MW

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 819-834 https://glytoucan.org/Structures/Glycans/G82109MW denotes keratan sulfate
T2 1433-1444 https://glytoucan.org/Structures/Glycans/G43702JT denotes Chondroitin
T3 1652-1673 https://glytoucan.org/Structures/Glycans/G27025MB denotes N-acetylgalactosamine
T4 1710-1720 https://glytoucan.org/Structures/Glycans/G00017MO denotes Hyaluronan
T5 1793-1808 https://glytoucan.org/Structures/Glycans/G82109MW denotes Keratan sulfate

sentences

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Keratocyte phenotype mediates proteoglycan structure: a role for fibroblasts in corneal fibrosis.
T2 98-297 Sentence denotes In pathological corneas, accumulation of fibrotic extracellular matrix is characterized by proteoglycans with altered glycosaminoglycans that contribute to the reduced transparency of scarred tissue.
T3 298-409 Sentence denotes During wound healing, keratocytes in the corneal stroma transdifferentiate into fibroblasts and myofibroblasts.
T4 410-650 Sentence denotes In this study, molecular markers were developed to identify keratocyte, fibroblast, and myofibroblast phenotypes in primary cultures of corneal stromal cells and the structure of glycosaminoglycans secreted by these cells was characterized.
T5 651-835 Sentence denotes Quiescent primary keratocytes expressed abundant protein and mRNA for keratocan and aldehyde dehydrogenase class 3 and secreted proteoglycans containing macromolecular keratan sulfate.
T6 836-1103 Sentence denotes Expression of these marker compounds was reduced in fibroblasts and also in transforming growth factor-beta-induced myofibroblasts, which expressed high levels of alpha-smooth muscle actin, biglycan, and the extra domain A (EDA or EIIIA) form of cellular fibronectin.
T7 1104-1191 Sentence denotes Collagen types I and III mRNAs were elevated in both fibroblasts and in myofibroblasts.
T8 1192-1300 Sentence denotes Expression of these molecular markers clearly distinguishes the phenotypic states of stromal cells in vitro.
T9 1301-1432 Sentence denotes Glycosaminoglycans secreted by fibroblasts and myofibroblasts were qualitatively similar to and differed from those of keratocytes.
T10 1433-1569 Sentence denotes Chondroitin/dermatan sulfate abundance, chain length, and sulfation were increased as keratocytes became fibroblasts and myofibroblasts.
T11 1570-1709 Sentence denotes Fluorophore-assisted carbohydrate electrophoresis analysis demonstrated increased N-acetylgalactosamine sulfation at both 4- and 6-carbons.
T12 1710-1792 Sentence denotes Hyaluronan, absent in keratocytes, was secreted by fibroblasts and myofibroblasts.
T13 1793-1917 Sentence denotes Keratan sulfate biosynthesis, chain length, and sulfation were significantly reduced in both fibroblasts and myofibroblasts.
T14 1918-2123 Sentence denotes The qualitatively similar expression of glycosaminoglycans shared by fibroblasts and myofibroblasts suggests a role for fibroblasts in deposition of non-transparent fibrotic tissue in pathological corneas.

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 819-834 http://www.glycoepitope.jp/epitopes/EP0085 denotes keratan sulfate
T2 1433-1444 http://www.glycoepitope.jp/epitopes/EP0081 denotes Chondroitin
T3 1793-1808 http://www.glycoepitope.jp/epitopes/EP0085 denotes Keratan sulfate

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1005-1018 http://purl.obolibrary.org/obo/MAT_0000303 denotes smooth muscle
T2 1012-1018 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 305-310 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T2 1060-1063 Disease denotes EDA http://purl.obolibrary.org/obo/MONDO_0016535

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1005-1018 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 819-834 Glycan denotes keratan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW
T2 1433-1444 Glycan denotes Chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 1793-1808 Glycan denotes Keratan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 819-834 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes keratan sulfate http://www.glycoepitope.jp/epitopes/EP0085
T2 1433-1444 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 1793-1808 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Keratan sulfate http://www.glycoepitope.jp/epitopes/EP0085

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 305-310 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178
T2 1060-1063 Disease denotes EDA http://purl.obolibrary.org/obo/MONDO_0016535

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 0-10 Cell denotes Keratocyte http://purl.obolibrary.org/obo/CL:0002363
T2 65-76 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T3 320-331 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T4 378-389 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T5 470-480 Cell denotes keratocyte http://purl.obolibrary.org/obo/CL:0002363
T6 482-492 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057
T7 554-567 Cell denotes stromal cells http://purl.obolibrary.org/obo/CL:0000499
T8 669-680 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T9 888-899 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T10 1113-1120 Cell denotes types I http://purl.obolibrary.org/obo/CL:0004120|http://purl.obolibrary.org/obo/CL:0004138
T12 1157-1168 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T13 1277-1290 Cell denotes stromal cells http://purl.obolibrary.org/obo/CL:0000499
T14 1332-1343 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T15 1420-1431 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T16 1519-1530 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T17 1538-1549 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T18 1732-1743 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T19 1761-1772 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T20 1886-1897 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T21 1987-1998 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T22 2038-2049 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-10 Body_part denotes Keratocyte http://purl.obolibrary.org/obo/CL_0002363
T2 65-76 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T3 114-121 Body_part denotes corneas http://purl.obolibrary.org/obo/UBERON_0000964
T4 148-168 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T5 290-296 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T6 320-331 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T7 339-353 Body_part denotes corneal stroma http://purl.obolibrary.org/obo/UBERON_0001777
T8 378-389 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T9 470-480 Body_part denotes keratocyte http://purl.obolibrary.org/obo/CL_0002363
T10 482-492 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057
T11 554-567 Body_part denotes stromal cells http://purl.obolibrary.org/obo/CL_0000499
T12 669-680 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T13 888-899 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T14 1005-1018 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135
T15 1157-1168 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T16 1277-1290 Body_part denotes stromal cells http://purl.obolibrary.org/obo/CL_0000499
T17 1332-1343 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T18 1420-1431 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T19 1519-1530 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T20 1538-1549 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T21 1732-1743 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T22 1761-1772 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T23 1886-1897 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T24 1987-1998 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T25 2038-2049 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T26 2092-2098 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T27 2115-2122 Body_part denotes corneas http://purl.obolibrary.org/obo/UBERON_0000964

GlyCosmos15-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1005-1018 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/MAT_0000303

sentences

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Keratocyte phenotype mediates proteoglycan structure: a role for fibroblasts in corneal fibrosis.
T2 98-297 Sentence denotes In pathological corneas, accumulation of fibrotic extracellular matrix is characterized by proteoglycans with altered glycosaminoglycans that contribute to the reduced transparency of scarred tissue.
T3 298-409 Sentence denotes During wound healing, keratocytes in the corneal stroma transdifferentiate into fibroblasts and myofibroblasts.
T4 410-650 Sentence denotes In this study, molecular markers were developed to identify keratocyte, fibroblast, and myofibroblast phenotypes in primary cultures of corneal stromal cells and the structure of glycosaminoglycans secreted by these cells was characterized.
T5 651-835 Sentence denotes Quiescent primary keratocytes expressed abundant protein and mRNA for keratocan and aldehyde dehydrogenase class 3 and secreted proteoglycans containing macromolecular keratan sulfate.
T6 836-1103 Sentence denotes Expression of these marker compounds was reduced in fibroblasts and also in transforming growth factor-beta-induced myofibroblasts, which expressed high levels of alpha-smooth muscle actin, biglycan, and the extra domain A (EDA or EIIIA) form of cellular fibronectin.
T7 1104-1191 Sentence denotes Collagen types I and III mRNAs were elevated in both fibroblasts and in myofibroblasts.
T8 1192-1300 Sentence denotes Expression of these molecular markers clearly distinguishes the phenotypic states of stromal cells in vitro.
T9 1301-1432 Sentence denotes Glycosaminoglycans secreted by fibroblasts and myofibroblasts were qualitatively similar to and differed from those of keratocytes.
T10 1433-1569 Sentence denotes Chondroitin/dermatan sulfate abundance, chain length, and sulfation were increased as keratocytes became fibroblasts and myofibroblasts.
T11 1570-1709 Sentence denotes Fluorophore-assisted carbohydrate electrophoresis analysis demonstrated increased N-acetylgalactosamine sulfation at both 4- and 6-carbons.
T12 1710-1792 Sentence denotes Hyaluronan, absent in keratocytes, was secreted by fibroblasts and myofibroblasts.
T13 1793-1917 Sentence denotes Keratan sulfate biosynthesis, chain length, and sulfation were significantly reduced in both fibroblasts and myofibroblasts.
T14 1918-2123 Sentence denotes The qualitatively similar expression of glycosaminoglycans shared by fibroblasts and myofibroblasts suggests a role for fibroblasts in deposition of non-transparent fibrotic tissue in pathological corneas.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-97 Sentence denotes Keratocyte phenotype mediates proteoglycan structure: a role for fibroblasts in corneal fibrosis.
T2 98-297 Sentence denotes In pathological corneas, accumulation of fibrotic extracellular matrix is characterized by proteoglycans with altered glycosaminoglycans that contribute to the reduced transparency of scarred tissue.
T3 298-409 Sentence denotes During wound healing, keratocytes in the corneal stroma transdifferentiate into fibroblasts and myofibroblasts.
T4 410-650 Sentence denotes In this study, molecular markers were developed to identify keratocyte, fibroblast, and myofibroblast phenotypes in primary cultures of corneal stromal cells and the structure of glycosaminoglycans secreted by these cells was characterized.
T5 651-835 Sentence denotes Quiescent primary keratocytes expressed abundant protein and mRNA for keratocan and aldehyde dehydrogenase class 3 and secreted proteoglycans containing macromolecular keratan sulfate.
T6 836-1103 Sentence denotes Expression of these marker compounds was reduced in fibroblasts and also in transforming growth factor-beta-induced myofibroblasts, which expressed high levels of alpha-smooth muscle actin, biglycan, and the extra domain A (EDA or EIIIA) form of cellular fibronectin.
T7 1104-1191 Sentence denotes Collagen types I and III mRNAs were elevated in both fibroblasts and in myofibroblasts.
T8 1192-1300 Sentence denotes Expression of these molecular markers clearly distinguishes the phenotypic states of stromal cells in vitro.
T9 1301-1432 Sentence denotes Glycosaminoglycans secreted by fibroblasts and myofibroblasts were qualitatively similar to and differed from those of keratocytes.
T10 1433-1569 Sentence denotes Chondroitin/dermatan sulfate abundance, chain length, and sulfation were increased as keratocytes became fibroblasts and myofibroblasts.
T11 1570-1709 Sentence denotes Fluorophore-assisted carbohydrate electrophoresis analysis demonstrated increased N-acetylgalactosamine sulfation at both 4- and 6-carbons.
T12 1710-1792 Sentence denotes Hyaluronan, absent in keratocytes, was secreted by fibroblasts and myofibroblasts.
T13 1793-1917 Sentence denotes Keratan sulfate biosynthesis, chain length, and sulfation were significantly reduced in both fibroblasts and myofibroblasts.
T14 1918-2123 Sentence denotes The qualitatively similar expression of glycosaminoglycans shared by fibroblasts and myofibroblasts suggests a role for fibroblasts in deposition of non-transparent fibrotic tissue in pathological corneas.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 819-834 Glycan denotes keratan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW
T2 1433-1444 Glycan denotes Chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 1793-1808 Glycan denotes Keratan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 819-834 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes keratan sulfate http://www.glycoepitope.jp/epitopes/EP0085
T2 1433-1444 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 1793-1808 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Keratan sulfate http://www.glycoepitope.jp/epitopes/EP0085

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-10 Body_part denotes Keratocyte http://purl.obolibrary.org/obo/CL_0002363
T2 65-76 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T3 114-121 Body_part denotes corneas http://purl.obolibrary.org/obo/UBERON_0000964
T4 148-168 Body_part denotes extracellular matrix http://purl.obolibrary.org/obo/GO_0031012
T5 290-296 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T6 320-331 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T7 339-353 Body_part denotes corneal stroma http://purl.obolibrary.org/obo/UBERON_0001777
T8 378-389 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T9 470-480 Body_part denotes keratocyte http://purl.obolibrary.org/obo/CL_0002363
T10 482-492 Body_part denotes fibroblast http://purl.obolibrary.org/obo/CL_0000057
T11 554-567 Body_part denotes stromal cells http://purl.obolibrary.org/obo/CL_0000499
T12 669-680 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T13 888-899 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T14 1005-1018 Body_part denotes smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135
T15 1157-1168 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T16 1277-1290 Body_part denotes stromal cells http://purl.obolibrary.org/obo/CL_0000499
T17 1332-1343 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T18 1420-1431 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T19 1519-1530 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T20 1538-1549 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T21 1732-1743 Body_part denotes keratocytes http://purl.obolibrary.org/obo/CL_0002363
T22 1761-1772 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T23 1886-1897 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T24 1987-1998 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T25 2038-2049 Body_part denotes fibroblasts http://purl.obolibrary.org/obo/CL_0000057
T26 2092-2098 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T27 2115-2122 Body_part denotes corneas http://purl.obolibrary.org/obo/UBERON_0000964

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 0-10 Cell denotes Keratocyte http://purl.obolibrary.org/obo/CL:0002363
T2 65-76 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T3 320-331 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T4 378-389 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T5 470-480 Cell denotes keratocyte http://purl.obolibrary.org/obo/CL:0002363
T6 482-492 Cell denotes fibroblast http://purl.obolibrary.org/obo/CL:0000057
T7 554-567 Cell denotes stromal cells http://purl.obolibrary.org/obo/CL:0000499
T8 669-680 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T9 888-899 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T10 1113-1120 Cell denotes types I http://purl.obolibrary.org/obo/CL:0004120|http://purl.obolibrary.org/obo/CL:0004138
T12 1157-1168 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T13 1277-1290 Cell denotes stromal cells http://purl.obolibrary.org/obo/CL:0000499
T14 1332-1343 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T15 1420-1431 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T16 1519-1530 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T17 1538-1549 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T18 1732-1743 Cell denotes keratocytes http://purl.obolibrary.org/obo/CL:0002363
T19 1761-1772 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T20 1886-1897 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T21 1987-1998 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057
T22 2038-2049 Cell denotes fibroblasts http://purl.obolibrary.org/obo/CL:0000057