| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-84 |
Sentence |
denotes |
Postoperative myalgia after succinylcholine: no evidence for an inflammatory origin. |
| T2 |
85-96 |
Sentence |
denotes |
UNLABELLED: |
| T3 |
97-175 |
Sentence |
denotes |
A common side effect associated with succinylcholine is postoperative myalgia. |
| T4 |
176-291 |
Sentence |
denotes |
The pathogenesis of this myalgia is still unclear; inflammation has been suggested but without convincing evidence. |
| T5 |
292-398 |
Sentence |
denotes |
We designed the present study to investigate whether an inflammatory reaction contributes to this myalgia. |
| T6 |
399-575 |
Sentence |
denotes |
The incidence and severity of succinylcholine-associated myalgia was determined in 64 patients pretreated with saline or dexamethasone before succinylcholine (n = 32 for each). |
| T7 |
576-662 |
Sentence |
denotes |
Incidence and severity of myalgia did not differ significantly between the two groups: |
| T8 |
663-871 |
Sentence |
denotes |
15 patients in the dexamethasone group complained of myalgia compared with 18 patients in the saline group, and severe myalgia was reported by five patients and three patients, respectively (not significant). |
| T9 |
872-968 |
Sentence |
denotes |
At 48 h after surgery, 12 patients in both groups still suffered from myalgia (not significant). |
| T10 |
969-1103 |
Sentence |
denotes |
In addition, interleukin-6 (IL-6) as an early marker of inflammation was assessed in a subgroup of 10 patients pretreated with saline. |
| T11 |
1104-1264 |
Sentence |
denotes |
We found an increase of IL-6 for only three patients, but only one patient reported myalgia; no relationship between myalgia and the increase of IL-6 was found. |
| T12 |
1265-1366 |
Sentence |
denotes |
In conclusion, there is no evidence for an inflammatory origin of succinylcholine-associated myalgia. |
| T13 |
1367-1380 |
Sentence |
denotes |
IMPLICATIONS: |
| T14 |
1381-1547 |
Sentence |
denotes |
Administration of dexamethasone before succinylcholine was not effective in decreasing the incidence or the severity of succinylcholine-induced postoperative myalgia. |
| T15 |
1548-1703 |
Sentence |
denotes |
Furthermore, there was no significant relationship between postoperative myalgia and time course of interleukin-6 concentrations, a marker of inflammation. |
| T16 |
1704-1808 |
Sentence |
denotes |
Pretreatment with dexamethasone is not justified to prevent postoperative myalgia after succinylcholine. |
| T1 |
0-84 |
Sentence |
denotes |
Postoperative myalgia after succinylcholine: no evidence for an inflammatory origin. |
| T2 |
85-96 |
Sentence |
denotes |
UNLABELLED: |
| T3 |
97-175 |
Sentence |
denotes |
A common side effect associated with succinylcholine is postoperative myalgia. |
| T4 |
176-291 |
Sentence |
denotes |
The pathogenesis of this myalgia is still unclear; inflammation has been suggested but without convincing evidence. |
| T5 |
292-398 |
Sentence |
denotes |
We designed the present study to investigate whether an inflammatory reaction contributes to this myalgia. |
| T6 |
399-575 |
Sentence |
denotes |
The incidence and severity of succinylcholine-associated myalgia was determined in 64 patients pretreated with saline or dexamethasone before succinylcholine (n = 32 for each). |
| T7 |
576-662 |
Sentence |
denotes |
Incidence and severity of myalgia did not differ significantly between the two groups: |
| T8 |
663-871 |
Sentence |
denotes |
15 patients in the dexamethasone group complained of myalgia compared with 18 patients in the saline group, and severe myalgia was reported by five patients and three patients, respectively (not significant). |
| T9 |
872-968 |
Sentence |
denotes |
At 48 h after surgery, 12 patients in both groups still suffered from myalgia (not significant). |
| T10 |
969-1103 |
Sentence |
denotes |
In addition, interleukin-6 (IL-6) as an early marker of inflammation was assessed in a subgroup of 10 patients pretreated with saline. |
| T11 |
1104-1264 |
Sentence |
denotes |
We found an increase of IL-6 for only three patients, but only one patient reported myalgia; no relationship between myalgia and the increase of IL-6 was found. |
| T12 |
1265-1366 |
Sentence |
denotes |
In conclusion, there is no evidence for an inflammatory origin of succinylcholine-associated myalgia. |
| T13 |
1367-1380 |
Sentence |
denotes |
IMPLICATIONS: |
| T14 |
1381-1547 |
Sentence |
denotes |
Administration of dexamethasone before succinylcholine was not effective in decreasing the incidence or the severity of succinylcholine-induced postoperative myalgia. |
| T15 |
1548-1703 |
Sentence |
denotes |
Furthermore, there was no significant relationship between postoperative myalgia and time course of interleukin-6 concentrations, a marker of inflammation. |
| T16 |
1704-1808 |
Sentence |
denotes |
Pretreatment with dexamethasone is not justified to prevent postoperative myalgia after succinylcholine. |