> top > docs > PubMed:12746734 > annotations

PubMed:12746734 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-164 Sentence denotes Cebus apella, a nonhuman primate highly susceptible to neuroleptic side effects, carries the GLY9 dopamine receptor D3 associated with tardive dyskinesia in humans.
TextSentencer_T2 165-299 Sentence denotes Tardive dyskinesia (TD) is a severe side effect of traditional neuroleptics affecting a considerable number of schizophrenic patients.
TextSentencer_T3 300-518 Sentence denotes Accumulating evidence suggests the existence of a genetic disposition to TD and other extra pyramidal symptoms (EPS) most strongly linked to a ser/gly polymorphism in position 9 of the D3 dopamine receptor gene (DRD3).
TextSentencer_T4 519-664 Sentence denotes The Cebus apella monkey is the favored animal model to study TD and other EPS because of its high susceptibility to side effects of neuroleptics.
TextSentencer_T5 665-771 Sentence denotes We therefore determined the sequence of the DRD3 gene in this species and compared it with that of humans.
TextSentencer_T6 772-915 Sentence denotes We found that the highly TD susceptible C. apella monkey (n=21) carries the gly9/gly9 DRD3 genotype that has been associated with TD in humans.
TextSentencer_T7 916-1038 Sentence denotes Contrarily, C. apella did not carry the ser23 5HT2C allele that has been reported to increase TD susceptibility in humans.
T1 0-164 Sentence denotes Cebus apella, a nonhuman primate highly susceptible to neuroleptic side effects, carries the GLY9 dopamine receptor D3 associated with tardive dyskinesia in humans.
T2 165-299 Sentence denotes Tardive dyskinesia (TD) is a severe side effect of traditional neuroleptics affecting a considerable number of schizophrenic patients.
T3 300-518 Sentence denotes Accumulating evidence suggests the existence of a genetic disposition to TD and other extra pyramidal symptoms (EPS) most strongly linked to a ser/gly polymorphism in position 9 of the D3 dopamine receptor gene (DRD3).
T4 519-664 Sentence denotes The Cebus apella monkey is the favored animal model to study TD and other EPS because of its high susceptibility to side effects of neuroleptics.
T5 665-771 Sentence denotes We therefore determined the sequence of the DRD3 gene in this species and compared it with that of humans.
T6 772-915 Sentence denotes We found that the highly TD susceptible C. apella monkey (n=21) carries the gly9/gly9 DRD3 genotype that has been associated with TD in humans.
T7 916-1038 Sentence denotes Contrarily, C. apella did not carry the ser23 5HT2C allele that has been reported to increase TD susceptibility in humans.

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
12746734-0#98#118#gene1814 98-118 gene1814 denotes dopamine receptor D3
12746734-0#135#153#diseaseC0686347 135-153 diseaseC0686347 denotes tardive dyskinesia
12746734-0#135#153#diseaseC3714760 135-153 diseaseC3714760 denotes tardive dyskinesia
98#118#gene1814135#153#diseaseC0686347 12746734-0#98#118#gene1814 12746734-0#135#153#diseaseC0686347 associated_with dopamine receptor D3,tardive dyskinesia
98#118#gene1814135#153#diseaseC3714760 12746734-0#98#118#gene1814 12746734-0#135#153#diseaseC3714760 associated_with dopamine receptor D3,tardive dyskinesia

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T380 98-118 gene:1814 denotes dopamine receptor D3
T381 135-153 disease:C0686347 denotes tardive dyskinesia
R1 T380 T381 associated_with dopamine receptor D3,tardive dyskinesia
R2 T380 T381 associated_with dopamine receptor D3,tardive dyskinesia

DisGeNET

Id Subject Object Predicate Lexical cue
T0 98-118 gene:1814 denotes dopamine receptor D3
T1 135-153 disease:C0152115 denotes tardive dyskinesia
T2 98-118 gene:1814 denotes dopamine receptor D3
T3 135-153 disease:C0686347 denotes tardive dyskinesia
T4 512-516 gene:1814 denotes DRD3
T5 373-375 disease:C0686347 denotes TD
T6 512-516 gene:1814 denotes DRD3
T7 373-375 disease:C0152115 denotes TD
T8 858-862 gene:1814 denotes DRD3
T9 902-904 disease:C0152115 denotes TD
T10 858-862 gene:1814 denotes DRD3
T11 902-904 disease:C0686347 denotes TD
T12 858-862 gene:1814 denotes DRD3
T13 797-799 disease:C0152115 denotes TD
T14 858-862 gene:1814 denotes DRD3
T15 797-799 disease:C0686347 denotes TD
R1 T0 T1 associated_with dopamine receptor D3,tardive dyskinesia
R2 T2 T3 associated_with dopamine receptor D3,tardive dyskinesia
R3 T4 T5 associated_with DRD3,TD
R4 T6 T7 associated_with DRD3,TD
R5 T8 T9 associated_with DRD3,TD
R6 T10 T11 associated_with DRD3,TD
R7 T12 T13 associated_with DRD3,TD
R8 T14 T15 associated_with DRD3,TD