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PubMed:12549952 JSONTXT

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PubmedHPO

Id Subject Object Predicate Lexical cue
T1 108-121 HP_0001399 denotes liver failure

PubCasesHPO

Id Subject Object Predicate Lexical cue
AB1 250-265 HP:0000836 denotes hyperthyroidism
AB2 638-644 HP:0100806 denotes sepsis

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-70 Sentence denotes Acute liver failure with concurrent bupropion and carbimazole therapy.
TextSentencer_T2 71-81 Sentence denotes OBJECTIVE:
TextSentencer_T3 82-191 Sentence denotes To report a case of fatal liver failure possibly associated with concurrent use of bupropion and carbimazole.
TextSentencer_T4 192-205 Sentence denotes CASE SUMMARY:
TextSentencer_T5 206-337 Sentence denotes A 41-year-old Chinese man with a history of hyperthyroidism had been treated with carbimazole and propranolol for the past 5 years.
TextSentencer_T6 338-442 Sentence denotes He received a 10-day course of bupropion as an aid for smoking cessation 10 weeks prior to presentation.
TextSentencer_T7 443-519 Sentence denotes He developed acute liver failure with rapid deterioration of renal function.
TextSentencer_T8 520-596 Sentence denotes Liver biopsy showed evidence of nonspecific drug-induced acute liver injury.
TextSentencer_T9 597-662 Sentence denotes His condition was further complicated by sepsis and coagulopathy.
TextSentencer_T10 663-714 Sentence denotes Death resulted 19 days after the onset of symptoms.
TextSentencer_T11 715-836 Sentence denotes The likelihood that bupropion induced hepatotoxicity in our patient was possible, based on the Naranjo probability scale.
TextSentencer_T12 837-848 Sentence denotes DISCUSSION:
TextSentencer_T13 849-1093 Sentence denotes Although there is increasing evidence of hepatotoxicity induced by bupropion, this is the first case of fatality that could have resulted from acute liver failure in a patient receiving bupropion while on concomitant treatment with carbimazole.
TextSentencer_T14 1094-1106 Sentence denotes CONCLUSIONS:
TextSentencer_T15 1107-1244 Sentence denotes Clinicians should be aware of the possibility of acute liver insult induced by bupropion given concurrently with other hepatotoxic drugs.
T1 0-70 Sentence denotes Acute liver failure with concurrent bupropion and carbimazole therapy.
T2 71-81 Sentence denotes OBJECTIVE:
T3 82-191 Sentence denotes To report a case of fatal liver failure possibly associated with concurrent use of bupropion and carbimazole.
T4 192-205 Sentence denotes CASE SUMMARY:
T5 206-337 Sentence denotes A 41-year-old Chinese man with a history of hyperthyroidism had been treated with carbimazole and propranolol for the past 5 years.
T6 338-442 Sentence denotes He received a 10-day course of bupropion as an aid for smoking cessation 10 weeks prior to presentation.
T7 443-519 Sentence denotes He developed acute liver failure with rapid deterioration of renal function.
T8 520-596 Sentence denotes Liver biopsy showed evidence of nonspecific drug-induced acute liver injury.
T9 597-662 Sentence denotes His condition was further complicated by sepsis and coagulopathy.
T10 663-714 Sentence denotes Death resulted 19 days after the onset of symptoms.
T11 715-836 Sentence denotes The likelihood that bupropion induced hepatotoxicity in our patient was possible, based on the Naranjo probability scale.
T12 837-848 Sentence denotes DISCUSSION:
T13 849-1093 Sentence denotes Although there is increasing evidence of hepatotoxicity induced by bupropion, this is the first case of fatality that could have resulted from acute liver failure in a patient receiving bupropion while on concomitant treatment with carbimazole.
T14 1094-1106 Sentence denotes CONCLUSIONS:
T15 1107-1244 Sentence denotes Clinicians should be aware of the possibility of acute liver insult induced by bupropion given concurrently with other hepatotoxic drugs.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 6-11 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T2 108-113 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 462-467 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T4 583-588 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T5 998-1003 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T6 1162-1167 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T7 830-835 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale

PubCasesORDO

Id Subject Object Predicate Lexical cue
TI1 0-19 ORDO:90062 denotes Acute liver failure
AB1 456-475 ORDO:90062 denotes acute liver failure
AB2 992-1011 ORDO:90062 denotes acute liver failure

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 6-11 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T2 108-113 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T3 462-467 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T4 520-525 http://purl.obolibrary.org/obo/UBERON_0002107 denotes Liver
PD-UBERON-AE-B_T5 583-588 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T6 998-1003 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T7 1162-1167 http://purl.obolibrary.org/obo/UBERON_0002107 denotes liver
PD-UBERON-AE-B_T8 830-835 http://purl.obolibrary.org/obo/UBERON_0002542 denotes scale

bc5cdr-valid-experiment

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 890-904 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 992-1011 Disease denotes acute liver failure
T20 1035-1044 Chemical denotes bupropion
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult
T23 1186-1195 Chemical denotes bupropion
T24 1226-1237 Disease denotes hepatotoxic

bc5cdr-valid-deepseek-nr-ng

Id Subject Object Predicate Lexical cue
T1 6-19 Disease denotes liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 165-174 Chemical denotes bupropion
T5 179-190 Chemical denotes carbimazole
T6 304-315 Chemical denotes propranolol
T7 369-378 Chemical denotes bupropion
T8 462-475 Disease denotes liver failure
T9 504-518 Disease denotes renal function
T10 583-595 Disease denotes liver injury
T11 638-644 Disease denotes sepsis
T12 649-661 Disease denotes coagulopathy
T13 735-744 Chemical denotes bupropion
T14 753-767 Disease denotes hepatotoxicity
T15 916-925 Chemical denotes bupropion
T16 998-1011 Disease denotes liver failure
T17 1081-1092 Chemical denotes carbimazole
T18 1162-1174 Disease denotes liver insult

bc5cdr-valid-gemini-r-ng

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 102-121 Disease denotes fatal liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 552-595 Disease denotes nonspecific drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 890-904 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 992-1011 Disease denotes acute liver failure
T20 1035-1044 Chemical denotes bupropion
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult
T23 1186-1195 Chemical denotes bupropion

bc5cdr-valid

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 890-904 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 992-1011 Disease denotes acute liver failure
T20 1035-1044 Chemical denotes bupropion
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult
T23 1186-1195 Chemical denotes bupropion
T24 1226-1237 Disease denotes hepatotoxic

bc5cdr-valid-gemini-r-g

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 953-961 Disease denotes fatality
T20 992-1011 Disease denotes acute liver failure
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-gemini-nr-g

Id Subject Object Predicate Lexical cue
T1 6-19 Disease denotes liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 992-1011 Disease denotes acute liver failure
T20 1035-1044 Chemical denotes bupropion
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-gemini-nr-ng

Id Subject Object Predicate Lexical cue
T1 6-19 Disease denotes liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 916-925 Chemical denotes bupropion
T18 992-1011 Disease denotes acute liver failure
T19 1035-1044 Chemical denotes bupropion
T20 1081-1092 Chemical denotes carbimazole
T21 1156-1174 Disease denotes acute liver insult
T22 1226-1243 Disease denotes hepatotoxic drugs

bc5cdr-valid-gpt-r-ng

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 890-904 Disease denotes hepatotoxicity
T18 916-925 Chemical denotes bupropion
T19 992-1011 Disease denotes acute liver failure
T20 1035-1044 Chemical denotes bupropion
T21 1081-1092 Chemical denotes carbimazole
T22 1156-1174 Disease denotes acute liver insult
T23 1186-1195 Chemical denotes bupropion

bc5cdr-valid-gpt-nr-ng

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 102-121 Disease denotes fatal liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 753-767 Disease denotes hepatotoxicity
T16 890-904 Disease denotes hepatotoxicity
T17 916-925 Chemical denotes bupropion
T18 992-1011 Disease denotes acute liver failure
T19 1035-1044 Chemical denotes bupropion
T20 1081-1092 Chemical denotes carbimazole
T21 1156-1174 Disease denotes acute liver insult
T22 1186-1195 Chemical denotes bupropion

bc5cdr-valid-gpt-r-g

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 890-904 Disease denotes hepatotoxicity
T19 916-925 Chemical denotes bupropion
T20 992-1011 Disease denotes acute liver failure
T21 1035-1044 Chemical denotes bupropion
T22 1081-1092 Chemical denotes carbimazole
T23 1156-1174 Disease denotes acute liver insult
T24 1186-1195 Chemical denotes bupropion

bc5cdr-valid-gpt-nr-g

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 890-904 Disease denotes hepatotoxicity
T19 916-925 Chemical denotes bupropion
T20 953-961 Disease denotes fatality
T21 992-1011 Disease denotes acute liver failure
T22 1035-1044 Chemical denotes bupropion
T23 1081-1092 Chemical denotes carbimazole
T24 1156-1174 Disease denotes acute liver insult
T25 1186-1195 Chemical denotes bupropion

bc5cdr-valid-deepseek-r-ng

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 102-121 Disease denotes fatal liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 577-595 Disease denotes acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-gemini-r-m

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 564-595 Disease denotes drug-induced acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 735-744 Chemical denotes bupropion
T16 753-767 Disease denotes hepatotoxicity
T17 916-925 Chemical denotes bupropion
T18 992-1011 Disease denotes acute liver failure
T19 1035-1044 Chemical denotes bupropion
T20 1081-1092 Chemical denotes carbimazole
T21 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-gpt-r-m2

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 577-595 Disease denotes acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 890-904 Disease denotes hepatotoxicity
T19 916-925 Chemical denotes bupropion
T20 953-961 Disease denotes fatality
T21 992-1011 Disease denotes acute liver failure
T22 1035-1044 Chemical denotes bupropion
T23 1081-1092 Chemical denotes carbimazole
T24 1156-1174 Disease denotes acute liver insult
T25 1186-1195 Chemical denotes bupropion

bc5cdr-valid-deepseek-r-g

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 304-315 Chemical denotes propranolol
T9 456-475 Disease denotes acute liver failure
T10 577-595 Disease denotes acute liver injury
T11 638-644 Disease denotes sepsis
T12 649-661 Disease denotes coagulopathy
T13 663-668 Disease denotes Death
T14 753-767 Disease denotes hepatotoxicity
T15 916-925 Chemical denotes bupropion
T16 1081-1092 Chemical denotes carbimazole
T17 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-deepseek-nr-g

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 165-174 Chemical denotes bupropion
T5 179-190 Chemical denotes carbimazole
T6 250-265 Disease denotes hyperthyroidism
T7 304-315 Chemical denotes propranolol
T8 456-475 Disease denotes acute liver failure
T9 504-518 Disease denotes renal function
T10 552-595 Disease denotes nonspecific drug-induced acute liver injury
T11 638-644 Disease denotes sepsis
T12 649-661 Disease denotes coagulopathy
T13 735-744 Chemical denotes bupropion
T14 753-767 Disease denotes hepatotoxicity
T15 916-925 Chemical denotes bupropion
T16 992-1011 Disease denotes acute liver failure
T17 1081-1092 Chemical denotes carbimazole
T18 1156-1174 Disease denotes acute liver insult
T19 1226-1243 Chemical denotes hepatotoxic drugs

bc5cdr-valid-deepseek-r-m

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 304-315 Chemical denotes propranolol
T9 456-475 Disease denotes acute liver failure
T10 577-595 Disease denotes acute liver injury
T11 638-644 Disease denotes sepsis
T12 649-661 Disease denotes coagulopathy
T13 663-668 Disease denotes Death
T14 753-767 Disease denotes hepatotoxicity
T15 1156-1174 Disease denotes acute liver insult

bc5cdr-valid-gpt-r-m

Id Subject Object Predicate Lexical cue
T1 0-19 Disease denotes Acute liver failure
T2 36-45 Chemical denotes bupropion
T3 50-61 Chemical denotes carbimazole
T4 108-121 Disease denotes liver failure
T5 165-174 Chemical denotes bupropion
T6 179-190 Chemical denotes carbimazole
T7 250-265 Disease denotes hyperthyroidism
T8 288-299 Chemical denotes carbimazole
T9 304-315 Chemical denotes propranolol
T10 369-378 Chemical denotes bupropion
T11 456-475 Disease denotes acute liver failure
T12 577-595 Disease denotes acute liver injury
T13 638-644 Disease denotes sepsis
T14 649-661 Disease denotes coagulopathy
T15 663-668 Disease denotes Death
T16 735-744 Chemical denotes bupropion
T17 753-767 Disease denotes hepatotoxicity
T18 890-904 Disease denotes hepatotoxicity
T19 916-925 Chemical denotes bupropion
T20 992-1011 Disease denotes acute liver failure
T21 1035-1044 Chemical denotes bupropion
T22 1081-1092 Chemical denotes carbimazole
T23 1186-1195 Chemical denotes bupropion