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Preeclampsia

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 1349-1361 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 2742-2754 ORPHA:275555 denotes preeclampsia

Preeclampsia-compare

Id Subject Object Predicate Lexical cue
PD-Preeclampsia-B_T1 1349-1361 ORPHA:275555 denotes preeclampsia
PD-Preeclampsia-B_T2 2742-2754 ORPHA:275555 denotes preeclampsia

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 115-123 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T2 371-379 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T3 525-533 http://purl.obolibrary.org/obo/UBERON_0001637 denotes Arteries
PD-UBERON-AE-B_T4 1163-1171 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T5 1305-1313 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T6 1702-1710 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T7 271-282 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T8 347-358 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T9 323-343 http://purl.obolibrary.org/obo/UBERON_0034768 denotes morphologic features
PD-UBERON-AE-B_T10 1093-1113 http://purl.obolibrary.org/obo/UBERON_0034768 denotes morphologic features

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-151 Sentence denotes Vascular endothelial growth factor induced functional and morphologic signs of endothelial dysfunction in isolated arteries from normal pregnant women.
TextSentencer_T2 152-162 Sentence denotes OBJECTIVE:
TextSentencer_T3 163-407 Sentence denotes The purpose of this study was to determine the effects of vascular endothelial growth factor on basal tone, endothelium-dependent dilatation, permeability, and morphologic features of endothelium in isolated arteries from normal pregnant women.
TextSentencer_T4 408-510 Sentence denotes We hypothesized that vascular endothelial growth factor might induce signs of endothelial dysfunction.
TextSentencer_T5 511-524 Sentence denotes STUDY DESIGN:
TextSentencer_T6 525-694 Sentence denotes Arteries (approximately 200 microm) were dissected from subcutaneous fat biopsy specimens that were obtained at cesarean delivery and mounted on a pressure arteriograph.
TextSentencer_T7 695-1035 Sentence denotes Changes in basal tone, dilatation to bradykinin (1 nmol/L to 3 micromol/L) before, during, and after 3 hours of incubation with vascular endothelial growth factor (0.5 or 1 nmol/L), vascular endothelial growth factor (0.5 nmol/L) plus bosentan (a nonselective endothelin receptor A and B antagonist, 1 micromol/L), or vehicle were compared.
TextSentencer_T8 1036-1114 Sentence denotes Scanning electron microscopy was applied for endothelial morphologic features.
TextSentencer_T9 1115-1362 Sentence denotes Permeability to Evans blue dye was evaluated in arteries after incubation with vascular endothelial growth factor, vascular endothelial growth factor plus angiopoietin-1, or vehicle, and in arteries that were obtained from women with preeclampsia.
TextSentencer_T10 1363-1371 Sentence denotes RESULTS:
TextSentencer_T11 1372-1553 Sentence denotes Basal tone was higher after 60 minutes of incubation with vascular endothelial growth factor (0.5 nmol/L) compared with vehicle (29% +/- 5% [n = 10] vs 10% +/- 4% [n = 7], P =.006).
TextSentencer_T12 1554-1654 Sentence denotes Combination of vascular endothelial growth factor with bosentan failed to increase the tone (n = 4).
TextSentencer_T13 1655-1798 Sentence denotes Bradykinin-mediated dilatation was impaired in arteries that were incubated with vascular endothelial growth factor 0.5 nmol/L (max dilatation:
TextSentencer_T14 1799-1911 Sentence denotes 287% +/- 16% vs 160% +/- 23% [n = 10], P =.0001) or vascular endothelial growth factor 1 nmol/L (max dilatation:
TextSentencer_T15 1912-1957 Sentence denotes 207% +/- 21% vs 88% +/- 4% [n = 3], P =.003).
TextSentencer_T16 1958-2118 Sentence denotes Bradykinin-mediated dilatation was similar after incubation with vehicle (n = 7) or the combination of vascular endothelial growth factor plus bosentan (n = 4).
TextSentencer_T17 2119-2262 Sentence denotes Evans blue dye staining was higher after incubation with vascular endothelial growth factor but was reversed by the addition of angiopoietin-1.
TextSentencer_T18 2263-2343 Sentence denotes Scanning electron microscopy demonstrated the development of intercellular gaps.
TextSentencer_T19 2344-2355 Sentence denotes CONCLUSION:
TextSentencer_T20 2356-2472 Sentence denotes Vascular endothelial growth factor impaired bradykinin-mediated dilatation and enhanced basal tone and permeability.
TextSentencer_T21 2473-2608 Sentence denotes This might indicate a potential role for vascular endothelial growth factor in the development of endothelial dysfunction in pregnancy.
TextSentencer_T22 2609-2755 Sentence denotes Angiopoietin-1 inhibited the vascular endothelial growth factor-induced vascular leakage, which may have therapeutic implications in preeclampsia.
T1 0-151 Sentence denotes Vascular endothelial growth factor induced functional and morphologic signs of endothelial dysfunction in isolated arteries from normal pregnant women.
T2 152-162 Sentence denotes OBJECTIVE:
T3 163-407 Sentence denotes The purpose of this study was to determine the effects of vascular endothelial growth factor on basal tone, endothelium-dependent dilatation, permeability, and morphologic features of endothelium in isolated arteries from normal pregnant women.
T4 408-510 Sentence denotes We hypothesized that vascular endothelial growth factor might induce signs of endothelial dysfunction.
T5 511-524 Sentence denotes STUDY DESIGN:
T6 525-694 Sentence denotes Arteries (approximately 200 microm) were dissected from subcutaneous fat biopsy specimens that were obtained at cesarean delivery and mounted on a pressure arteriograph.
T7 695-1035 Sentence denotes Changes in basal tone, dilatation to bradykinin (1 nmol/L to 3 micromol/L) before, during, and after 3 hours of incubation with vascular endothelial growth factor (0.5 or 1 nmol/L), vascular endothelial growth factor (0.5 nmol/L) plus bosentan (a nonselective endothelin receptor A and B antagonist, 1 micromol/L), or vehicle were compared.
T8 1036-1114 Sentence denotes Scanning electron microscopy was applied for endothelial morphologic features.
T9 1115-1362 Sentence denotes Permeability to Evans blue dye was evaluated in arteries after incubation with vascular endothelial growth factor, vascular endothelial growth factor plus angiopoietin-1, or vehicle, and in arteries that were obtained from women with preeclampsia.
T10 1363-1371 Sentence denotes RESULTS:
T11 1372-1553 Sentence denotes Basal tone was higher after 60 minutes of incubation with vascular endothelial growth factor (0.5 nmol/L) compared with vehicle (29% +/- 5% [n = 10] vs 10% +/- 4% [n = 7], P =.006).
T12 1554-1654 Sentence denotes Combination of vascular endothelial growth factor with bosentan failed to increase the tone (n = 4).
T13 1655-1798 Sentence denotes Bradykinin-mediated dilatation was impaired in arteries that were incubated with vascular endothelial growth factor 0.5 nmol/L (max dilatation:
T14 1799-1911 Sentence denotes 287% +/- 16% vs 160% +/- 23% [n = 10], P =.0001) or vascular endothelial growth factor 1 nmol/L (max dilatation:
T15 1912-1957 Sentence denotes 207% +/- 21% vs 88% +/- 4% [n = 3], P =.003).
T16 1958-2118 Sentence denotes Bradykinin-mediated dilatation was similar after incubation with vehicle (n = 7) or the combination of vascular endothelial growth factor plus bosentan (n = 4).
T17 2119-2262 Sentence denotes Evans blue dye staining was higher after incubation with vascular endothelial growth factor but was reversed by the addition of angiopoietin-1.
T18 2263-2343 Sentence denotes Scanning electron microscopy demonstrated the development of intercellular gaps.
T19 2344-2355 Sentence denotes CONCLUSION:
T20 2356-2472 Sentence denotes Vascular endothelial growth factor impaired bradykinin-mediated dilatation and enhanced basal tone and permeability.
T21 2473-2608 Sentence denotes This might indicate a potential role for vascular endothelial growth factor in the development of endothelial dysfunction in pregnancy.
T22 2609-2755 Sentence denotes Angiopoietin-1 inhibited the vascular endothelial growth factor-induced vascular leakage, which may have therapeutic implications in preeclampsia.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 115-123 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T2 371-379 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T3 1163-1171 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T4 1305-1313 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T5 1702-1710 http://purl.obolibrary.org/obo/UBERON_0001637 denotes arteries
PD-UBERON-AE-B_T6 271-282 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T7 347-358 http://purl.obolibrary.org/obo/UBERON_0001986 denotes endothelium
PD-UBERON-AE-B_T8 323-343 http://purl.obolibrary.org/obo/UBERON_0034768 denotes morphologic features
PD-UBERON-AE-B_T9 1093-1113 http://purl.obolibrary.org/obo/UBERON_0034768 denotes morphologic features

preeclampsia_genes

Id Subject Object Predicate Lexical cue
PD-PreeclampsiaGenes-B_T1 0-34 HGNC:VEGFA denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T2 221-255 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T3 429-463 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T4 823-857 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T5 877-911 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T6 1194-1228 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T7 1230-1264 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T8 1430-1464 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T9 1569-1603 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T10 1736-1770 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T11 1851-1885 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T12 2061-2095 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T13 2176-2210 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T14 2356-2390 HGNC:VEGFA denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T15 2514-2548 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T16 2638-2672 HGNC:VEGFA denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T17 0-34 HGNC:VEGFB denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T18 221-255 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T19 429-463 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T20 823-857 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T21 877-911 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T22 1194-1228 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T23 1230-1264 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T24 1430-1464 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T25 1569-1603 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T26 1736-1770 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T27 1851-1885 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T28 2061-2095 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T29 2176-2210 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T30 2356-2390 HGNC:VEGFB denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T31 2514-2548 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T32 2638-2672 HGNC:VEGFB denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T33 0-34 HGNC:VEGFC denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T34 221-255 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T35 429-463 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T36 823-857 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T37 877-911 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T38 1194-1228 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T39 1230-1264 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T40 1430-1464 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T41 1569-1603 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T42 1736-1770 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T43 1851-1885 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T44 2061-2095 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T45 2176-2210 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T46 2356-2390 HGNC:VEGFC denotes Vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T47 2514-2548 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T48 2638-2672 HGNC:VEGFC denotes vascular endothelial growth factor
PD-PreeclampsiaGenes-B_T49 1270-1284 HGNC:ANGPT1 denotes angiopoietin-1
PD-PreeclampsiaGenes-B_T50 2247-2261 HGNC:ANGPT1 denotes angiopoietin-1
PD-PreeclampsiaGenes-B_T51 2609-2623 HGNC:ANGPT1 denotes Angiopoietin-1