PubMed:12433458 JSONTXT

{"project":"GlyCosmos600-FMA","denotations":[{"id":"T1","span":{"begin":66,"end":78},"obj":"Body_part"},{"id":"T2","span":{"begin":186,"end":189},"obj":"Body_part"},{"id":"T3","span":{"begin":224,"end":236},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"fma_id","subj":"T1","obj":"http://purl.org/sig/ont/fma/fma82737"},{"id":"A2","pred":"fma_id","subj":"T2","obj":"http://purl.org/sig/ont/fma/fma24890"},{"id":"A3","pred":"fma_id","subj":"T3","obj":"http://purl.org/sig/ont/fma/fma82737"}],"text":"Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}

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of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}

{"project":"HP-phenotype","denotations":[{"id":"T1","span":{"begin":108,"end":132},"obj":"Phenotype"},{"id":"T2","span":{"begin":199,"end":223},"obj":"Phenotype"}],"attributes":[{"id":"A1","pred":"hp_id","subj":"T1","obj":"HP:0001402"},{"id":"A2","pred":"hp_id","subj":"T2","obj":"HP:0001402"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}

{"project":"mondo_disease","denotations":[{"id":"T1","span":{"begin":108,"end":132},"obj":"Disease"},{"id":"T2","span":{"begin":199,"end":223},"obj":"Disease"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MONDO_0007256"},{"id":"A2","pred":"mondo_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/MONDO_0007256"}],"text":"Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}

{"project":"NCBITAXON","denotations":[{"id":"T1","span":{"begin":102,"end":107},"obj":"OrganismTaxon"},{"id":"T2","span":{"begin":193,"end":198},"obj":"OrganismTaxon"}],"attributes":[{"id":"A1","pred":"db_id","subj":"T1","obj":"9606"},{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"}],"text":"Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T1","span":{"begin":186,"end":189},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0001460"},{"id":"A2","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0003822"}],"text":"Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma.\nA disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB(1a), namely, 2-aminoethyl 3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 3)-2-acetamido-2-deoxy-beta-D-galactopyranosyl-(1 --\u003e 4)-3-O-sulfo-beta-D-galactopyranosyl-(1 --\u003e 4)-beta-D-glucopyranoside was synthesized via a [2 + 1 + 1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors."}