Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-58 |
Sentence |
denotes |
Urea cycle disorders in Thai infants: a report of 5 cases. |
TextSentencer_T2 |
59-244 |
Sentence |
denotes |
Urea Cycle Disorders (UCD) is an inborn error of urea synthesis in which ammonium and other nitrogenous precursors of urea accumulate leading to episodic coma and a high mortality rate. |
TextSentencer_T3 |
245-357 |
Sentence |
denotes |
Therapy with peritoneal dialysis, essential amino acids or their nitrogen-free analogues has increased survival. |
TextSentencer_T4 |
358-474 |
Sentence |
denotes |
The authors report 5 cases of urea cycle disorders, all of whom developed and were rescued from hyperammonemic coma. |
TextSentencer_T5 |
475-524 |
Sentence |
denotes |
However, the eventual outcome was quite variable. |
TextSentencer_T6 |
525-573 |
Sentence |
denotes |
Argininosuccinate lyase deficiency (ALD) Case 1. |
TextSentencer_T7 |
574-797 |
Sentence |
denotes |
A 2 month old male infant, a product of a consanguineous marriage (Suphanburi province); developed poor feeding on day 7, lethargy, convulsion, hepatomegaly and respiratory alkalosis leading to respiratory failure and coma. |
TextSentencer_T8 |
798-917 |
Sentence |
denotes |
Hyperammonemia, elevation of glutamic acid and argininosuccinic acid and its anhydrides confirmed the diagnosis of ALD. |
TextSentencer_T9 |
918-962 |
Sentence |
denotes |
He is now 9 years old and severely retarded. |
TextSentencer_T10 |
963-970 |
Sentence |
denotes |
Case 2. |
TextSentencer_T11 |
971-1260 |
Sentence |
denotes |
A male infant with history of lethargy, poor feeding on day 3, treated as sepsis and required respiratory support for 6 days; subsequently readmitted at age 2 weeks with vomitting, lethargy, seizure activity and hyperammonemia, and was treated by a local pediatrician in Songkhla province. |
TextSentencer_T12 |
1261-1481 |
Sentence |
denotes |
There was a history of parental consanguinity and he was referred to Siriraj Hospital on day 64 with severe essential amino acid deficiency and acrodermatitis enteropathica with markedly elevated plasma citrulline level. |
TextSentencer_T13 |
1482-1570 |
Sentence |
denotes |
In spite of aggressive treatment; the patient developed sepsis and he expired on day 78. |
TextSentencer_T14 |
1571-1622 |
Sentence |
denotes |
Ornithine transcarbamylase deficiency (OTC) Case 3. |
TextSentencer_T15 |
1623-1821 |
Sentence |
denotes |
An eleven-month-old male infant, the product of a non-consanguineous marriage, developed neonatal onset of hyperammonemia on day 5 after poor feeding, lethargy, hypothermia, seizure, apnea and coma. |
TextSentencer_T16 |
1822-1970 |
Sentence |
denotes |
He was rescued from neonatal hyperammonemic coma on day 9 after aggressive treatment, but expired at eleven months of age after overwhelming sepsis. |
TextSentencer_T17 |
1971-1978 |
Sentence |
denotes |
Case 4. |
TextSentencer_T18 |
1979-2083 |
Sentence |
denotes |
A male infant, sibling of case 3 was referred to Siriraj Hospital on day 8 with hyperammonemia and coma. |
TextSentencer_T19 |
2084-2248 |
Sentence |
denotes |
In spite of intensive genetic counseling given after the birth of their first child with OTC, the couple chose to have another baby without informing any physician. |
TextSentencer_T20 |
2249-2338 |
Sentence |
denotes |
The baby developed vomiting and lethargy on day 2; subsequently hyperammonemia was noted. |
TextSentencer_T21 |
2339-2484 |
Sentence |
denotes |
In spite of aggressive treatment given; hepatic dysfunction, renal failure and disseminated intravascular coagulation defects occurred on day 15. |
TextSentencer_T22 |
2485-2569 |
Sentence |
denotes |
He expired on day 18 after parental permission for discontinuation of all treatment. |
TextSentencer_T23 |
2570-2633 |
Sentence |
denotes |
Argininosuccinate synthetase deficiency (ASS) or Citrullinemia. |
TextSentencer_T24 |
2634-2641 |
Sentence |
denotes |
Case 5. |
TextSentencer_T25 |
2642-2790 |
Sentence |
denotes |
A seven week old female infant, the product of a consanguineous marriage and of Pakistani ethnic origin; developed intermittent vomiting from day 6. |
TextSentencer_T26 |
2791-3042 |
Sentence |
denotes |
Initial diagnoses included ruminations, sepsis and pyloric stenosis for which she was operated on (day 30); however, vomiting continued; subsequently seizures, hyperammonemic coma developed and she was rescued from hyperammonemic coma within 30 hours. |
TextSentencer_T27 |
3043-3114 |
Sentence |
denotes |
Significant elevations of citrulline and L-glutamine were demonstrated. |
TextSentencer_T28 |
3115-3204 |
Sentence |
denotes |
She was discharged in excellent condition to her home in Dubai, the United Arab Emirates. |
T1 |
0-58 |
Sentence |
denotes |
Urea cycle disorders in Thai infants: a report of 5 cases. |
T2 |
59-244 |
Sentence |
denotes |
Urea Cycle Disorders (UCD) is an inborn error of urea synthesis in which ammonium and other nitrogenous precursors of urea accumulate leading to episodic coma and a high mortality rate. |
T3 |
245-357 |
Sentence |
denotes |
Therapy with peritoneal dialysis, essential amino acids or their nitrogen-free analogues has increased survival. |
T4 |
358-474 |
Sentence |
denotes |
The authors report 5 cases of urea cycle disorders, all of whom developed and were rescued from hyperammonemic coma. |
T5 |
475-524 |
Sentence |
denotes |
However, the eventual outcome was quite variable. |
T6 |
525-573 |
Sentence |
denotes |
Argininosuccinate lyase deficiency (ALD) Case 1. |
T7 |
574-797 |
Sentence |
denotes |
A 2 month old male infant, a product of a consanguineous marriage (Suphanburi province); developed poor feeding on day 7, lethargy, convulsion, hepatomegaly and respiratory alkalosis leading to respiratory failure and coma. |
T8 |
798-917 |
Sentence |
denotes |
Hyperammonemia, elevation of glutamic acid and argininosuccinic acid and its anhydrides confirmed the diagnosis of ALD. |
T9 |
918-962 |
Sentence |
denotes |
He is now 9 years old and severely retarded. |
T10 |
963-970 |
Sentence |
denotes |
Case 2. |
T11 |
971-1260 |
Sentence |
denotes |
A male infant with history of lethargy, poor feeding on day 3, treated as sepsis and required respiratory support for 6 days; subsequently readmitted at age 2 weeks with vomitting, lethargy, seizure activity and hyperammonemia, and was treated by a local pediatrician in Songkhla province. |
T12 |
1261-1481 |
Sentence |
denotes |
There was a history of parental consanguinity and he was referred to Siriraj Hospital on day 64 with severe essential amino acid deficiency and acrodermatitis enteropathica with markedly elevated plasma citrulline level. |
T13 |
1482-1570 |
Sentence |
denotes |
In spite of aggressive treatment; the patient developed sepsis and he expired on day 78. |
T14 |
1571-1622 |
Sentence |
denotes |
Ornithine transcarbamylase deficiency (OTC) Case 3. |
T15 |
1623-1821 |
Sentence |
denotes |
An eleven-month-old male infant, the product of a non-consanguineous marriage, developed neonatal onset of hyperammonemia on day 5 after poor feeding, lethargy, hypothermia, seizure, apnea and coma. |
T16 |
1822-1970 |
Sentence |
denotes |
He was rescued from neonatal hyperammonemic coma on day 9 after aggressive treatment, but expired at eleven months of age after overwhelming sepsis. |
T17 |
1971-1978 |
Sentence |
denotes |
Case 4. |
T18 |
1979-2083 |
Sentence |
denotes |
A male infant, sibling of case 3 was referred to Siriraj Hospital on day 8 with hyperammonemia and coma. |
T19 |
2084-2248 |
Sentence |
denotes |
In spite of intensive genetic counseling given after the birth of their first child with OTC, the couple chose to have another baby without informing any physician. |
T20 |
2249-2338 |
Sentence |
denotes |
The baby developed vomiting and lethargy on day 2; subsequently hyperammonemia was noted. |
T21 |
2339-2484 |
Sentence |
denotes |
In spite of aggressive treatment given; hepatic dysfunction, renal failure and disseminated intravascular coagulation defects occurred on day 15. |
T22 |
2485-2569 |
Sentence |
denotes |
He expired on day 18 after parental permission for discontinuation of all treatment. |
T23 |
2570-2633 |
Sentence |
denotes |
Argininosuccinate synthetase deficiency (ASS) or Citrullinemia. |
T24 |
2634-2641 |
Sentence |
denotes |
Case 5. |
T25 |
2642-2790 |
Sentence |
denotes |
A seven week old female infant, the product of a consanguineous marriage and of Pakistani ethnic origin; developed intermittent vomiting from day 6. |
T26 |
2791-3042 |
Sentence |
denotes |
Initial diagnoses included ruminations, sepsis and pyloric stenosis for which she was operated on (day 30); however, vomiting continued; subsequently seizures, hyperammonemic coma developed and she was rescued from hyperammonemic coma within 30 hours. |
T27 |
3043-3114 |
Sentence |
denotes |
Significant elevations of citrulline and L-glutamine were demonstrated. |
T28 |
3115-3204 |
Sentence |
denotes |
She was discharged in excellent condition to her home in Dubai, the United Arab Emirates. |