PubMed:12379519 / 0-542 JSONTXT

{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":149,"end":324},"obj":"BACKGROUND"}],"text":"Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10.\nBACKGROUND: Matrix metalloproteinases (MMPs) have a pivotal role in the destruction of cartilage in rheumatoid arthritis (RA), which is mediated by the fibroblast-like synoviocytes (FLS).\nOBJECTIVE: To examine the in vitro invasiveness of synoviocytes obtained from inflamed joints of patients with arthritis in relation to the expression of MMP 1-14, 17, 19, cathepsin-K, the tissue inhibitors of matrix "}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"12379519-2#143#148#gene4312","span":{"begin":479,"end":484},"obj":"gene4312"},{"id":"12379519-2#161#172#gene1513","span":{"begin":497,"end":508},"obj":"gene1513"},{"id":"12379519-2#100#109#diseaseC0003864","span":{"begin":436,"end":445},"obj":"diseaseC0003864"}],"relations":[{"id":"143#148#gene4312100#109#diseaseC0003864","pred":"associated_with","subj":"12379519-2#143#148#gene4312","obj":"12379519-2#100#109#diseaseC0003864"},{"id":"161#172#gene1513100#109#diseaseC0003864","pred":"associated_with","subj":"12379519-2#161#172#gene1513","obj":"12379519-2#100#109#diseaseC0003864"}],"text":"Invasive properties of fibroblast-like synoviocytes: correlation with growth characteristics and expression of MMP-1, MMP-3, and MMP-10.\nBACKGROUND: Matrix metalloproteinases (MMPs) have a pivotal role in the destruction of cartilage in rheumatoid arthritis (RA), which is mediated by the fibroblast-like synoviocytes (FLS).\nOBJECTIVE: To examine the in vitro invasiveness of synoviocytes obtained from inflamed joints of patients with arthritis in relation to the expression of MMP 1-14, 17, 19, cathepsin-K, the tissue inhibitors of matrix "}