PubMed:12374875 / 88-501 JSONTXT

{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":0,"end":413},"obj":"BACKGROUND"}],"text":"The innate immune system of human skin contains antimicrobial peptides known as cathelicidins (LL-37) and beta-defensins. In normal skin these peptides are negligible, but they accumulate in skin affected by inflammatory diseases such as psoriasis. We compared the levels of expression of LL-37 and human beta-defensin 2 (HBD-2) in inflamed skin from patients with atopic dermatitis and from those with psoriasis."}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"12374875-3#40#45#gene820","span":{"begin":289,"end":294},"obj":"gene820"},{"id":"12374875-3#116#133#diseaseC0011615","span":{"begin":365,"end":382},"obj":"diseaseC0011615"},{"id":"12374875-3#116#133#diseaseC0013595","span":{"begin":365,"end":382},"obj":"diseaseC0013595"}],"relations":[{"id":"40#45#gene820116#133#diseaseC0011615","pred":"associated_with","subj":"12374875-3#40#45#gene820","obj":"12374875-3#116#133#diseaseC0011615"},{"id":"40#45#gene820116#133#diseaseC0013595","pred":"associated_with","subj":"12374875-3#40#45#gene820","obj":"12374875-3#116#133#diseaseC0013595"}],"text":"The innate immune system of human skin contains antimicrobial peptides known as cathelicidins (LL-37) and beta-defensins. In normal skin these peptides are negligible, but they accumulate in skin affected by inflammatory diseases such as psoriasis. We compared the levels of expression of LL-37 and human beta-defensin 2 (HBD-2) in inflamed skin from patients with atopic dermatitis and from those with psoriasis."}