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PubMed:12244074 JSONTXT

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Glycan-Motif

Id Subject Object Predicate Lexical cue
T1 77-97 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyl lactosamine
T2 726-737 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T3 987-998 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T4 1114-1134 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyl lactosamine
T5 1144-1151 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T6 1144-1151 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T7 1248-1262 https://glytoucan.org/Structures/Glycans/G13157WZ denotes 6-sulfo LacNAc
T8 1263-1270 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T9 1263-1270 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T10 1627-1647 https://glytoucan.org/Structures/Glycans/G64581RP denotes N-acetyl glucosamine

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 77-97 Glycan_Motif denotes N-acetyl lactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T2 726-737 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T3 987-998 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T4 1114-1134 Glycan_Motif denotes N-acetyl lactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO
T5 1144-1151 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T7 1248-1262 Glycan_Motif denotes 6-sulfo LacNAc https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G13157WZ
T8 1263-1270 Glycan_Motif denotes Lewis x https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G01187XC|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00051MO
T10 1627-1647 Glycan_Motif denotes N-acetyl glucosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G64581RP

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
TextSentencer_T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
TextSentencer_T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
TextSentencer_T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
TextSentencer_T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
TextSentencer_T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
TextSentencer_T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
TextSentencer_T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
TextSentencer_T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
TextSentencer_T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
TextSentencer_T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
TextSentencer_T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
TextSentencer_T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.
T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.
T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 77-97 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyl lactosamine
T2 726-737 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T3 987-998 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T4 1114-1134 https://glytoucan.org/Structures/Glycans/G00055MO denotes N-acetyl lactosamine
T5 1144-1151 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T6 1144-1151 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T7 1248-1262 https://glytoucan.org/Structures/Glycans/G13157WZ denotes 6-sulfo LacNAc
T8 1263-1270 https://glytoucan.org/Structures/Glycans/G00051MO denotes Lewis x
T9 1263-1270 https://glytoucan.org/Structures/Glycans/G01187XC denotes Lewis x
T10 1627-1647 https://glytoucan.org/Structures/Glycans/G64581RP denotes N-acetyl glucosamine

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 726-737 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T2 987-998 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T3 1144-1151 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
T4 1248-1262 http://www.glycoepitope.jp/epitopes/EP0141 denotes 6-sulfo LacNAc
T5 1263-1270 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 726-737 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T2 987-998 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 1136-1142 Glycan denotes LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR
T4 1144-1151 Glycan denotes Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO
T5 1248-1262 Glycan denotes 6-sulfo LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G13157WZ
T6 1263-1270 Glycan denotes Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 24-36 FMAID:82737 denotes carbohydrate
_T2 24-36 FMAID:197276 denotes carbohydrate
_T3 77-97 FMAID:82786 denotes N-acetyl lactosamine
_T4 77-97 FMAID:196780 denotes N-acetyl lactosamine
_T5 86-97 FMAID:82792 denotes lactosamine
_T6 86-97 FMAID:196787 denotes lactosamine
_T7 174-183 FMAID:167148 denotes leukocyte
_T8 174-183 FMAID:62852 denotes leukocyte
_T9 197-206 FMAID:167164 denotes monocytes
_T10 197-206 FMAID:62864 denotes monocytes
_T11 225-233 FMAID:84050 denotes cytokine
_T12 225-233 FMAID:197972 denotes cytokine
_T13 460-469 FMAID:197972 denotes cytokines
_T14 460-469 FMAID:84050 denotes cytokines
_T15 512-524 FMAID:197276 denotes carbohydrate
_T16 512-524 FMAID:82737 denotes carbohydrate
_T17 585-597 FMAID:212684 denotes cell surface
_T18 585-597 FMAID:200942 denotes cell surface
_T19 590-597 FMAID:146300 denotes surface
_T20 590-597 FMAID:50594 denotes surface
_T21 598-605 FMAID:67257 denotes protein
_T22 598-605 FMAID:165447 denotes protein
_T23 609-622 FMAID:171182 denotes myeloid cells
_T24 609-622 FMAID:199064 denotes myeloid cells
_T25 609-622 FMAID:70339 denotes myeloid cells
_T26 617-622 FMAID:169002 denotes cells
_T27 617-622 FMAID:68646 denotes cells
_T28 636-648 FMAID:171182 denotes myeloid cell
_T29 636-648 FMAID:70339 denotes myeloid cell
_T30 636-648 FMAID:199064 denotes myeloid cell
_T31 708-725 FMAID:63011 denotes glycosaminoglycan
_T32 708-725 FMAID:167395 denotes glycosaminoglycan
_T33 726-745 FMAID:196838 denotes chondroitin sulfate
_T34 726-745 FMAID:82837 denotes chondroitin sulfate
_T35 987-1006 FMAID:196838 denotes chondroitin sulfate
_T36 987-1006 FMAID:82837 denotes chondroitin sulfate
_T37 1114-1134 FMAID:82786 denotes N-acetyl lactosamine
_T38 1114-1134 FMAID:196780 denotes N-acetyl lactosamine
_T39 1123-1134 FMAID:196787 denotes lactosamine
_T40 1123-1134 FMAID:82792 denotes lactosamine
_T41 1161-1166 FMAID:169002 denotes cells
_T42 1161-1166 FMAID:68646 denotes cells
_T43 1203-1211 FMAID:167180 denotes antibody
_T44 1417-1430 FMAID:197276 denotes carbohydrates
_T45 1417-1430 FMAID:82737 denotes carbohydrates
_T46 1434-1447 FMAID:199064 denotes myeloid cells
_T47 1434-1447 FMAID:171182 denotes myeloid cells
_T48 1434-1447 FMAID:70339 denotes myeloid cells
_T49 1442-1447 FMAID:68646 denotes cells
_T50 1442-1447 FMAID:169002 denotes cells
_T51 1504-1516 FMAID:82737 denotes carbohydrate
_T52 1504-1516 FMAID:197276 denotes carbohydrate
_T53 1627-1647 FMAID:196781 denotes N-acetyl glucosamine
_T54 1627-1647 FMAID:82787 denotes N-acetyl glucosamine
_T55 1636-1647 FMAID:196792 denotes glucosamine
_T56 1636-1647 FMAID:82797 denotes glucosamine
_T57 1691-1704 FMAID:171182 denotes myeloid cells
_T58 1691-1704 FMAID:199064 denotes myeloid cells
_T59 1691-1704 FMAID:70339 denotes myeloid cells
_T60 1699-1704 FMAID:68646 denotes cells
_T61 1699-1704 FMAID:169002 denotes cells

uniprot-human

Id Subject Object Predicate Lexical cue
T1 0-3 http://www.uniprot.org/uniprot/P01375 denotes TNF
T2 263-266 http://www.uniprot.org/uniprot/P01375 denotes TNF
T3 490-493 http://www.uniprot.org/uniprot/P01375 denotes TNF
T4 756-759 http://www.uniprot.org/uniprot/P01375 denotes TNF
T5 915-918 http://www.uniprot.org/uniprot/P01375 denotes TNF
T6 1070-1073 http://www.uniprot.org/uniprot/P01375 denotes TNF
T7 1457-1460 http://www.uniprot.org/uniprot/P01375 denotes TNF
T8 0-9 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T9 263-272 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T10 490-499 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T11 756-765 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T12 915-924 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T13 1070-1079 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T14 1457-1466 http://www.uniprot.org/uniprot/P01375 denotes TNF-alpha
T15 234-255 http://www.uniprot.org/uniprot/P01375 denotes tumor necrosis factor
T16 50-54 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T17 126-130 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T18 285-289 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T19 343-347 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T20 422-426 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T21 538-542 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T22 544-548 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T23 671-675 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T24 788-792 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T25 898-902 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T26 965-969 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T27 1359-1363 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T28 1388-1392 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T29 1540-1544 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T30 1683-1687 http://www.uniprot.org/uniprot/Q9UCB0 denotes CD44
T31 234-255 http://www.uniprot.org/uniprot/Q06643 denotes tumor necrosis factor
T32 490-507 http://www.uniprot.org/uniprot/P26022 denotes TNF-alpha induces
T33 915-932 http://www.uniprot.org/uniprot/P26022 denotes TNF-alpha induced
T34 1070-1087 http://www.uniprot.org/uniprot/P26022 denotes TNF-alpha induced
T35 490-507 http://www.uniprot.org/uniprot/P98066 denotes TNF-alpha induces
T36 915-932 http://www.uniprot.org/uniprot/P98066 denotes TNF-alpha induced
T37 1070-1087 http://www.uniprot.org/uniprot/P98066 denotes TNF-alpha induced
T38 490-507 http://www.uniprot.org/uniprot/P20827 denotes TNF-alpha induces
T39 915-932 http://www.uniprot.org/uniprot/P20827 denotes TNF-alpha induced
T40 1070-1087 http://www.uniprot.org/uniprot/P20827 denotes TNF-alpha induced
T41 490-507 http://www.uniprot.org/uniprot/Q03169 denotes TNF-alpha induces
T42 915-932 http://www.uniprot.org/uniprot/Q03169 denotes TNF-alpha induced
T43 1070-1087 http://www.uniprot.org/uniprot/Q03169 denotes TNF-alpha induced
T44 490-507 http://www.uniprot.org/uniprot/P21580 denotes TNF-alpha induces
T45 915-932 http://www.uniprot.org/uniprot/P21580 denotes TNF-alpha induced
T46 1070-1087 http://www.uniprot.org/uniprot/P21580 denotes TNF-alpha induced
T47 490-507 http://www.uniprot.org/uniprot/O95379 denotes TNF-alpha induces
T48 915-932 http://www.uniprot.org/uniprot/O95379 denotes TNF-alpha induced
T49 1070-1087 http://www.uniprot.org/uniprot/O95379 denotes TNF-alpha induced

uniprot-mouse

Id Subject Object Predicate Lexical cue
T1 0-3 http://www.uniprot.org/uniprot/P06804 denotes TNF
T2 263-266 http://www.uniprot.org/uniprot/P06804 denotes TNF
T3 490-493 http://www.uniprot.org/uniprot/P06804 denotes TNF
T4 756-759 http://www.uniprot.org/uniprot/P06804 denotes TNF
T5 915-918 http://www.uniprot.org/uniprot/P06804 denotes TNF
T6 1070-1073 http://www.uniprot.org/uniprot/P06804 denotes TNF
T7 1457-1460 http://www.uniprot.org/uniprot/P06804 denotes TNF
T8 0-9 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T9 263-272 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T10 490-499 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T11 756-765 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T12 915-924 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T13 1070-1079 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T14 1457-1466 http://www.uniprot.org/uniprot/P06804 denotes TNF-alpha
T15 234-255 http://www.uniprot.org/uniprot/P06804 denotes tumor necrosis factor
T16 50-54 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T17 126-130 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T18 285-289 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T19 343-347 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T20 422-426 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T21 538-542 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T22 544-548 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T23 671-675 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T24 788-792 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T25 898-902 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T26 965-969 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T27 1359-1363 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T28 1388-1392 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T29 1540-1544 http://www.uniprot.org/uniprot/Q62409 denotes CD44
T30 1683-1687 http://www.uniprot.org/uniprot/Q62409 denotes CD44

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 366-372 http://purl.bioontology.org/ontology/STY/T051 denotes events
T2 617-622 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T3 1161-1166 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T4 1192-1202 http://purl.bioontology.org/ontology/NCBITAXON/608684 denotes monoclonal
T5 1442-1447 http://purl.bioontology.org/ontology/STY/T025 denotes cells
T6 1699-1704 http://purl.bioontology.org/ontology/STY/T025 denotes cells

GO-BP

Id Subject Object Predicate Lexical cue
T1 37-46 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T2 135-144 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T3 290-299 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T4 409-418 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T5 525-534 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T6 676-685 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T7 793-802 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T8 858-867 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T9 970-979 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T10 1046-1055 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfation
T11 576-584 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfated
T12 738-745 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T13 999-1006 http://purl.obolibrary.org/obo/GO_0051923 denotes sulfate
T14 174-192 http://purl.obolibrary.org/obo/GO_0007159 denotes leukocyte adhesion
T15 240-248 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T16 240-248 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T17 240-248 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T18 240-248 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T19 585-605 http://purl.obolibrary.org/obo/GO_0034394 denotes cell surface protein
T20 585-605 http://purl.obolibrary.org/obo/GO_0033575 denotes cell surface protein
T21 585-605 http://purl.obolibrary.org/obo/GO_0033580 denotes cell surface protein

GO-MF

Id Subject Object Predicate Lexical cue
T1 1203-1211 http://purl.obolibrary.org/obo/GO_0003823 denotes antibody

GO-CC

Id Subject Object Predicate Lexical cue
T1 585-589 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T2 617-622 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T3 1161-1166 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T4 1442-1447 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T5 1699-1704 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T6 585-597 http://purl.obolibrary.org/obo/GO_0009986 denotes cell surface

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 24-36 http://edamontology.org/topic_0152 denotes carbohydrate
T2 512-524 http://edamontology.org/topic_0152 denotes carbohydrate
T3 598-605 http://edamontology.org/topic_0078 denotes protein
T4 1417-1430 http://edamontology.org/topic_0152 denotes carbohydrates
T5 1504-1516 http://edamontology.org/topic_0152 denotes carbohydrate

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 310-320 http://edamontology.org/operation_3465 denotes correlates
T2 598-605 http://edamontology.org/format_1208 denotes protein
T3 598-605 http://edamontology.org/data_1467 denotes protein
T4 1178-1186 http://edamontology.org/operation_2423 denotes detected
T5 1370-1382 http://edamontology.org/operation_2246 denotes demonstrates
T6 1562-1574 http://edamontology.org/operation_2246 denotes demonstrates

GlycoBiology-Motifs

Id Subject Object Predicate Lexical cue
T1 86-97 http://rdf.glycoinfo.org/glycan/G00055MO denotes lactosamine
T2 1123-1134 http://rdf.glycoinfo.org/glycan/G00055MO denotes lactosamine
T3 726-737 http://rdf.glycoinfo.org/glycan/G00018MO denotes chondroitin
T4 987-998 http://rdf.glycoinfo.org/glycan/G00018MO denotes chondroitin
T5 726-745 http://rdf.glycoinfo.org/glycan/G00018MO denotes chondroitin sulfate
T6 987-1006 http://rdf.glycoinfo.org/glycan/G00018MO denotes chondroitin sulfate
T7 1144-1149 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T8 1263-1268 http://rdf.glycoinfo.org/glycan/G00047MO denotes Lewis
T9 1144-1151 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x
T10 1263-1270 http://rdf.glycoinfo.org/glycan/G00051MO denotes Lewis x

GlycoBiology-Epitope

Id Subject Object Predicate Lexical cue
PD-GlycoEpitope-B_T1 1144-1151 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T2 1263-1270 http://www.glycoepitope.jp/epitopes/EP0011 denotes Lewis x
PD-GlycoEpitope-B_T3 726-737 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
PD-GlycoEpitope-B_T4 987-998 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
PD-GlycoEpitope-B_T5 1248-1262 http://www.glycoepitope.jp/epitopes/EP0141 denotes 6-sulfo LacNAc

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 234-239 Disease denotes tumor http://purl.obolibrary.org/obo/MONDO_0005070

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 234-239 Phenotype denotes tumor HP:0002664

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 726-737 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T2 987-998 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 1144-1151 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis x http://www.glycoepitope.jp/epitopes/EP0011
T4 1248-1262 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes 6-sulfo LacNAc http://www.glycoepitope.jp/epitopes/EP0141
T5 1263-1270 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis x http://www.glycoepitope.jp/epitopes/EP0011

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 234-239 Phenotype denotes tumor HP:0002664

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 174-183 Body_part denotes leukocyte http://purl.obolibrary.org/obo/CL_0000738
T2 197-206 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T4 609-622 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763
T5 636-648 Body_part denotes myeloid cell http://purl.obolibrary.org/obo/CL_0000763
T6 1434-1447 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763
T7 1691-1704 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763

GlyCosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 174-183 Cell denotes leukocyte http://purl.obolibrary.org/obo/CL:0000738
T2 197-206 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T4 609-622 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763
T5 636-648 Cell denotes myeloid cell http://purl.obolibrary.org/obo/CL:0000763
T6 1434-1447 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763
T7 1691-1704 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
TextSentencer_T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
TextSentencer_T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
TextSentencer_T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
TextSentencer_T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
TextSentencer_T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
TextSentencer_T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
TextSentencer_T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
TextSentencer_T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
TextSentencer_T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
TextSentencer_T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
TextSentencer_T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
TextSentencer_T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.
T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.
T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-125 Sentence denotes TNF-alpha increases the carbohydrate sulfation of CD44: induction of 6-sulfo N-acetyl lactosamine on N- and O-linked glycans.
T2 126-193 Sentence denotes CD44 and sulfation have both been implicated in leukocyte adhesion.
T3 194-373 Sentence denotes In monocytes, the inflammatory cytokine tumor necrosis factor alpha (TNF-alpha) stimulates CD44 sulfation, and this correlates with the induction of CD44-mediated adhesion events.
T4 374-470 Sentence denotes However, little is known about the sulfation of CD44 or its induction by inflammatory cytokines.
T5 471-543 Sentence denotes We determined that TNF-alpha induces the carbohydrate sulfation of CD44.
T6 544-623 Sentence denotes CD44 was established as a major sulfated cell surface protein on myeloid cells.
T7 624-746 Sentence denotes In the SR91 myeloid cell line, the majority of CD44 sulfation was attributed to the glycosaminoglycan chondroitin sulfate.
T8 747-903 Sentence denotes However, TNF-alpha stimulation increased CD44 sulfation two- to threefold, largely attributed to the increased sulfation of N- and O-linked glycans on CD44.
T9 904-1056 Sentence denotes Therefore, TNF-alpha induced a decrease in the percentage of CD44 sulfation due to chondroitin sulfate and an increase due to N- and O-linked sulfation.
T10 1057-1242 Sentence denotes Furthermore, TNF-alpha induced the expression of 6-sulfo N-acetyl lactosamine (LacNAc)/Lewis x on these cells, which was detected by a monoclonal antibody after neuraminidase treatment.
T11 1243-1364 Sentence denotes This 6-sulfo LacNAc/Lewis x epitope was induced on N-linked and (to a lesser extent) on O-linked glycans present on CD44.
T12 1365-1545 Sentence denotes This demonstrates that CD44 is modified by sulfated carbohydrates in myeloid cells and that TNF-alpha modifies both the type and amount of carbohydrate sulfation occurring on CD44.
T13 1546-1705 Sentence denotes In addition, it demonstrates that TNF-alpha can induce the expression of 6-sulfo N-acetyl glucosamine on both N- and O-linked glycans of CD44 in myeloid cells.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 726-737 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T2 987-998 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 1136-1142 Glycan denotes LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G66213AR
T4 1144-1151 Glycan denotes Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO
T5 1248-1262 Glycan denotes 6-sulfo LacNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G13157WZ
T6 1263-1270 Glycan denotes Lewis x https://api.glycosmos.org/wurcs2image/latest/png/binary/G00051MO

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 726-737 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T2 987-998 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 1144-1151 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis x http://www.glycoepitope.jp/epitopes/EP0011
T4 1248-1262 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes 6-sulfo LacNAc http://www.glycoepitope.jp/epitopes/EP0141
T5 1263-1270 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes Lewis x http://www.glycoepitope.jp/epitopes/EP0011

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 234-239 Disease denotes tumor MONDO:0005070

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 174-183 Body_part denotes leukocyte http://purl.obolibrary.org/obo/CL_0000738
T2 197-206 Body_part denotes monocytes http://purl.obolibrary.org/obo/CL_0000576|http://purl.obolibrary.org/obo/CL_0001054
T4 609-622 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763
T5 636-648 Body_part denotes myeloid cell http://purl.obolibrary.org/obo/CL_0000763
T6 1434-1447 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763
T7 1691-1704 Body_part denotes myeloid cells http://purl.obolibrary.org/obo/CL_0000763

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 174-183 Cell denotes leukocyte http://purl.obolibrary.org/obo/CL:0000738
T2 197-206 Cell denotes monocytes http://purl.obolibrary.org/obo/CL:0000576|http://purl.obolibrary.org/obo/CL:0001054
T4 609-622 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763
T5 636-648 Cell denotes myeloid cell http://purl.obolibrary.org/obo/CL:0000763
T6 1434-1447 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763
T7 1691-1704 Cell denotes myeloid cells http://purl.obolibrary.org/obo/CL:0000763