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Glycosmos15-CL

Id Subject Object Predicate Lexical cue cl_id
T1 99-108 Cell denotes fat cells http://purl.obolibrary.org/obo/CL:0000136
T2 268-276 Cell denotes platelet http://purl.obolibrary.org/obo/CL:0000233
T3 395-404 Cell denotes fat cells http://purl.obolibrary.org/obo/CL:0000136
T4 435-444 Cell denotes fat cells http://purl.obolibrary.org/obo/CL:0000136
T5 587-595 Cell denotes platelet http://purl.obolibrary.org/obo/CL:0000233
T6 762-771 Cell denotes fat cells http://purl.obolibrary.org/obo/CL:0000136
T7 1728-1753 Cell denotes cells and skeletal muscle http://purl.obolibrary.org/obo/CL:0000188

GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 332-339 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG
T2 470-477 Glycan_Motif denotes glucose https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G15021LG

sentences

Id Subject Object Predicate Lexical cue
T1 0-164 Sentence denotes Epidermal growth factor and transforming growth factor alpha mimic the effects of insulin in human fat cells and augment downstream signaling in insulin resistance.
T2 165-405 Sentence denotes The ability of the growth factors epidermal growth factor (EGF), transforming growth factor alpha, and platelet-derived growth factor to exert insulin-like effects on glucose transport and lipolysis were examined in human and rat fat cells.
T3 406-698 Sentence denotes No effects were found in rat fat cells, whereas EGF (EC(50) for glucose transport approximately 0.02 nm) and transforming growth factor alpha (EC(50) approximately 0.2 nm), but not platelet-derived growth factor, mimicked the effects of insulin (EC(50) approximately 0.2 nm) on both pathways.
T4 699-808 Sentence denotes EGF receptors, but not EGF, were abundantly expressed in human fat cells as well as in human skeletal muscle.
T5 809-1265 Sentence denotes EGF increased the tyrosine phosphorylation of several proteins (the EGF receptor, insulin receptor substrate (IRS)-1, IRS-2, and Grb2-associated binder 1), whereas Shc and Gab2 were only weakly and inconsistently phosphorylated. p85, the regulatory subunit of phosphatidylinositol 3-kinase (PI 3-kinase), was also found to associate with all of these docking molecules, showing that EGF activated PI 3-kinase pools that were additional to those of insulin.
T6 1266-1462 Sentence denotes EGF and/or insulin increased protein kinase B/Akt serine phosphorylation to a similar extent, whereas mitogen-activated protein kinase phosphorylation was more pronounced for EGF than for insulin.
T7 1463-1655 Sentence denotes The impaired insulin-stimulated downstream signaling, measured as protein kinase B/Akt serine phosphorylation, in insulin-resistant cells (Type 2 diabetes) was improved by the addition of EGF.
T8 1656-1754 Sentence denotes Thus, EGF receptors, but not EGF, are abundantly expressed in human fat cells and skeletal muscle.
T9 1755-1883 Sentence denotes EGF mimics the effects of insulin on both the metabolic and mitogenic pathways but utilize in part different signaling pathways.
T10 1884-2157 Sentence denotes Both insulin and EGF increase the tyrosine phosphorylation and activation of IRS-1 and IRS-2, whereas EGF is also capable of activating additional PI 3-kinase pools and, thus, can augment the downstream signaling of insulin in insulin-resistant states like Type 2 diabetes.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 332-339 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose
T2 470-477 https://glytoucan.org/Structures/Glycans/G15021LG denotes glucose

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 792-807 http://purl.obolibrary.org/obo/MAT_0000302 denotes skeletal muscle
T2 801-807 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle
T3 1738-1753 http://purl.obolibrary.org/obo/MAT_0000302 denotes skeletal muscle
T4 1747-1753 http://purl.obolibrary.org/obo/MAT_0000025 denotes muscle

FSU-PRGE

Id Subject Object Predicate Lexical cue
T1 0-23 protein denotes Epidermal growth factor
T2 28-60 protein denotes transforming growth factor alpha
T3 82-89 protein denotes insulin
T4 145-152 protein denotes insulin
T5 184-198 protein denotes growth factors
T6 199-222 protein denotes epidermal growth factor
T7 224-227 protein denotes EGF
T8 230-262 protein denotes transforming growth factor alpha
T9 268-298 protein denotes platelet-derived growth factor
T10 308-315 protein denotes insulin
T11 454-457 protein denotes EGF
T12 515-547 protein denotes transforming growth factor alpha
T13 587-617 protein denotes platelet-derived growth factor
T14 643-650 protein denotes insulin
T15 699-712 protein denotes EGF receptors
T16 722-725 protein denotes EGF
T17 809-812 protein denotes EGF
T18 877-889 protein denotes EGF receptor
T19 891-925 protein denotes insulin receptor substrate (IRS)-1
T20 927-932 protein denotes IRS-2
T21 938-962 protein denotes Grb2-associated binder 1
T22 973-976 protein denotes Shc
T23 981-985 protein denotes Gab2
T24 1038-1041 protein denotes p85
T25 1047-1098 protein denotes regulatory subunit of phosphatidylinositol 3-kinase
T26 1100-1111 protein denotes PI 3-kinase
T27 1192-1195 protein denotes EGF
T28 1206-1217 protein denotes PI 3-kinase
T29 1257-1264 protein denotes insulin
T30 1266-1269 protein denotes EGF
T31 1277-1284 protein denotes insulin
T32 1295-1311 protein denotes protein kinase B
T33 1312-1315 protein denotes Akt
T34 1368-1400 protein denotes mitogen-activated protein kinase
T35 1441-1444 protein denotes EGF
T36 1454-1461 protein denotes insulin
T37 1476-1483 protein denotes insulin
T38 1529-1545 protein denotes protein kinase B
T39 1546-1549 protein denotes Akt
T40 1577-1584 protein denotes insulin
T41 1651-1654 protein denotes EGF
T42 1662-1675 protein denotes EGF receptors
T43 1685-1688 protein denotes EGF
T44 1755-1758 protein denotes EGF
T45 1781-1788 protein denotes insulin
T46 1889-1896 protein denotes insulin
T47 1901-1904 protein denotes EGF
T48 1961-1966 protein denotes IRS-1
T49 1971-1976 protein denotes IRS-2
T50 1986-1989 protein denotes EGF
T51 2031-2042 protein denotes PI 3-kinase
T52 2100-2107 protein denotes insulin
T53 2111-2118 protein denotes insulin

PIR-corpus2

Id Subject Object Predicate Lexical cue
T1 0-23 protein denotes Epidermal growth factor
T2 28-60 protein denotes transforming growth factor alpha
T3 82-89 protein denotes insulin
T4 145-152 protein denotes insulin
T5 199-228 protein denotes epidermal growth factor (EGF)
T6 230-262 protein denotes transforming growth factor alpha
T7 268-298 protein denotes platelet-derived growth factor
T8 308-315 protein denotes insulin
T9 454-457 protein denotes EGF
T10 515-547 protein denotes transforming growth factor alpha
T11 587-617 protein denotes platelet-derived growth factor
T12 643-650 protein denotes insulin
T13 699-712 protein denotes EGF receptors
T14 722-725 protein denotes EGF
T15 809-812 protein denotes EGF
T16 877-889 protein denotes EGF receptor
T17 891-925 protein denotes insulin receptor substrate (IRS)-1
T18 927-932 protein denotes IRS-2
T19 938-962 protein denotes Grb2-associated binder 1
T20 973-976 protein denotes Shc
T21 981-985 protein denotes Gab2
T22 1038-1041 protein denotes p85
T23 1047-1068 protein denotes regulatory subunit of
T24 1192-1195 protein denotes EGF
T25 1206-1208 protein denotes PI
T26 1257-1264 protein denotes insulin
T27 1266-1269 protein denotes EGF
T28 1277-1284 protein denotes insulin
T29 1295-1311 protein denotes protein kinase B
T30 1312-1315 protein denotes Akt
T31 1368-1400 protein denotes mitogen-activated protein kinase
T32 1441-1444 protein denotes EGF
T33 1454-1461 protein denotes insulin
T34 1476-1483 protein denotes insulin
T35 1529-1545 protein denotes protein kinase B
T36 1546-1549 protein denotes Akt
T37 1577-1584 protein denotes insulin
T38 1651-1654 protein denotes EGF
T39 1662-1675 protein denotes EGF receptors
T40 1685-1688 protein denotes EGF
T41 1755-1758 protein denotes EGF
T42 1781-1788 protein denotes insulin
T43 1889-1896 protein denotes insulin
T44 1901-1904 protein denotes EGF
T45 1961-1966 protein denotes IRS-1
T46 1971-1976 protein denotes IRS-2
T47 1986-1989 protein denotes EGF
T48 2031-2042 protein denotes PI 3-kinase
T49 2100-2107 protein denotes insulin
T50 2111-2118 protein denotes insulin

2015-BEL-Sample-2

Id Subject Object Predicate Lexical cue
BEL:20003032 809-962 p(HGNC:EGF) increases p(HGNC:EGFR,pmod(P,Y)) denotes EGF increased the tyrosine phosphorylation of several proteins (the EGF receptor, insulin receptor substrate (IRS)-1, IRS-2, and Grb2-associated binder 1

PIR-corpus1

Id Subject Object Predicate Lexical cue
T1 0-23 protein denotes Epidermal growth factor
T2 28-60 protein denotes transforming growth factor alpha
T3 82-89 protein denotes insulin
T4 145-152 protein denotes insulin
T5 184-198 protein denotes growth factors
T6 199-222 protein denotes epidermal growth factor
T7 224-227 acronym denotes EGF
T8 230-262 protein denotes transforming growth factor alpha
T9 268-298 protein denotes platelet-derived growth factor
T10 454-457 protein denotes EGF
T11 515-547 protein denotes transforming growth factor alpha
T12 587-617 protein denotes platelet-derived growth factor
T13 643-650 protein denotes insulin
T14 699-712 protein denotes EGF receptors
T15 722-725 protein denotes EGF
T16 809-812 protein denotes EGF
T17 863-871 protein denotes proteins
T18 877-889 protein denotes EGF receptor
T19 891-925 protein denotes insulin receptor substrate (IRS)-1
T20 927-932 protein denotes IRS-2
T21 938-962 protein denotes Grb2-associated binder 1
T22 973-976 protein denotes Shc
T23 981-985 protein denotes Gab2
T24 1038-1041 protein denotes p85
T25 1058-1068 protein denotes subunit of
T26 1100-1111 acronym denotes PI 3-kinase
T27 1168-1177 protein denotes molecules
T28 1192-1195 protein denotes EGF
T29 1206-1208 protein denotes PI
T30 1257-1264 protein denotes insulin
T31 1266-1269 protein denotes EGF
T32 1277-1284 protein denotes insulin
T33 1295-1315 protein denotes protein kinase B/Akt
T34 1368-1400 protein denotes mitogen-activated protein kinase
T35 1441-1444 protein denotes EGF
T36 1454-1461 protein denotes insulin
T37 1476-1483 protein denotes insulin
T38 1529-1549 protein denotes protein kinase B/Akt
T39 1651-1654 protein denotes EGF
T40 1662-1675 protein denotes EGF receptors
T41 1685-1688 protein denotes EGF
T42 1755-1758 protein denotes EGF
T43 1781-1788 protein denotes insulin
T44 1889-1896 protein denotes insulin
T45 1901-1904 protein denotes EGF
T46 1961-1966 protein denotes IRS-1
T47 1971-1976 protein denotes IRS-2
T48 1986-1989 protein denotes EGF
T49 2031-2042 protein denotes PI 3-kinase
T50 2100-2107 protein denotes insulin
T51 2111-2118 protein denotes insulin

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 1602-1617 Disease denotes Type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148
T2 2141-2156 Disease denotes Type 2 diabetes http://purl.obolibrary.org/obo/MONDO_0005148

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 93-98 OrganismTaxon denotes human 9606
T2 381-386 OrganismTaxon denotes human 9606
T3 391-394 OrganismTaxon denotes rat 10114|10116
T5 431-434 OrganismTaxon denotes rat 10114|10116
T7 756-761 OrganismTaxon denotes human 9606
T8 786-791 OrganismTaxon denotes human 9606
T9 1718-1723 OrganismTaxon denotes human 9606

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 792-807 Body_part denotes skeletal muscle http://purl.obolibrary.org/obo/MAT_0000302
T2 1738-1753 Body_part denotes skeletal muscle http://purl.obolibrary.org/obo/MAT_0000302

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-16 Body_part denotes Epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021
T2 99-108 Body_part denotes fat cells http://purl.obolibrary.org/obo/CL_0000136
T3 199-215 Body_part denotes epidermal growth http://purl.obolibrary.org/obo/UBERON_0000021
T4 268-276 Body_part denotes platelet http://purl.obolibrary.org/obo/CL_0000233
T5 395-404 Body_part denotes fat cells http://purl.obolibrary.org/obo/CL_0000136
T6 435-444 Body_part denotes fat cells http://purl.obolibrary.org/obo/CL_0000136
T7 587-595 Body_part denotes platelet http://purl.obolibrary.org/obo/CL_0000233
T8 762-771 Body_part denotes fat cells http://purl.obolibrary.org/obo/CL_0000136
T9 792-807 Body_part denotes skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134|http://purl.obolibrary.org/obo/UBERON_0014892|http://purl.obolibrary.org/obo/UBERON_0014895
T12 1724-1727 Body_part denotes fat http://purl.obolibrary.org/obo/UBERON_0001013
T13 1728-1753 Body_part denotes cells and skeletal muscle http://purl.obolibrary.org/obo/CL_0000188

GlyCosmos15-HP

Id Subject Object Predicate Lexical cue hp_id
T1 145-163 Phenotype denotes insulin resistance HP:0000855
T2 1577-1594 Phenotype denotes insulin-resistant HP:0000855
T3 1602-1617 Phenotype denotes Type 2 diabetes HP:0005978
T4 2111-2128 Phenotype denotes insulin-resistant HP:0000855
T5 2141-2156 Phenotype denotes Type 2 diabetes HP:0005978