PubMed:12023287
Annnotations
Glycosmos15-CL
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 481-492 | Cell | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL:0000232 |
PubTator4TogoVar
| Id | Subject | Object | Predicate | Lexical cue | proteinmutation |
|---|---|---|---|---|---|
| 12023287_0 | 1455-1460 | ProteinMutation | denotes | G271R | rs104893683 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 23-32 | Glycan_Motif | denotes | globoside | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
| T2 | 128-149 | Glycan_Motif | denotes | N-acetylgalactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB |
| T3 | 151-172 | Glycan_Motif | denotes | globotriaosylceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00059MO |
| T4 | 558-567 | Glycan_Motif | denotes | P antigen | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
| T5 | 582-591 | Glycan_Motif | denotes | globoside | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
| T6 | 1110-1119 | Glycan_Motif | denotes | globoside | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
| T7 | 1606-1615 | Glycan_Motif | denotes | globoside | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 23-32 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | globoside |
| T2 | 128-149 | https://glytoucan.org/Structures/Glycans/G27025MB | denotes | N-acetylgalactosamine |
| T3 | 151-172 | https://glytoucan.org/Structures/Glycans/G00059MO | denotes | globotriaosylceramide |
| T4 | 558-567 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | P antigen |
| T5 | 582-591 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | globoside |
| T6 | 1110-1119 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | globoside |
| T7 | 1606-1615 | https://glytoucan.org/Structures/Glycans/G00061MO | denotes | globoside |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-70 | Sentence | denotes | Molecular basis of the globoside-deficient P(k) blood group phenotype. |
| T2 | 71-219 | Sentence | denotes | Identification of four inactivating mutations in the UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase gene. |
| T3 | 220-429 | Sentence | denotes | The biochemistry and molecular genetics underlying the related carbohydrate blood group antigens P, P(k), and LKE in the GLOB collection and P1 in the P blood group system are complex and not fully understood. |
| T4 | 430-674 | Sentence | denotes | Individuals with the rare but clinically important erythrocyte phenotypes P(1)(k) and P(2)(k) lack the capability to synthesize P antigen identified as globoside, the cellular receptor for Parvo-B19 virus and some P-fimbriated Escherichia coli. |
| T5 | 675-811 | Sentence | denotes | As in the ABO system, naturally occurring antibodies, anti-P of the IgM and IgG class with hemolytic and cytotoxic capacity, are formed. |
| T6 | 812-1138 | Sentence | denotes | To define the molecular basis of the P(k) phenotype we analyzed the full coding region of a candidate gene reported in 1998 as a member of the 3-beta-galactosyltransferase family but later shown to possess UDP-N-acetylgalactosamine:globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase or globoside synthase activity. |
| T7 | 1139-1320 | Sentence | denotes | Homozygosity for different nonsense mutations (C(202) --> T and 538insA) resulting in premature stop codons was found in blood samples from two individuals of the P(2)(k) phenotype. |
| T8 | 1321-1563 | Sentence | denotes | Two individuals with P(1)(k) and P(2)(k) phenotypes were homozygous for missense mutations causing amino acid substitutions (E266A or G271R) in a highly conserved region of the enzymatically active carboxyl-terminal domain in the transferase. |
| T9 | 1564-1655 | Sentence | denotes | We conclude that crucial mutations in the globoside synthase gene cause the P(k) phenotype. |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 23-32 | http://www.glycoepitope.jp/epitopes/EP0073 | denotes | globoside |
| T2 | 582-591 | http://www.glycoepitope.jp/epitopes/EP0073 | denotes | globoside |
| T3 | 1110-1119 | http://www.glycoepitope.jp/epitopes/EP0073 | denotes | globoside |
| T4 | 1606-1615 | http://www.glycoepitope.jp/epitopes/EP0073 | denotes | globoside |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 48-53 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 48-53 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T3 | 296-301 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T4 | 296-301 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T5 | 373-378 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T6 | 373-378 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
| T7 | 995-1000 | http://purl.obolibrary.org/obo/MAT_0000488 | denotes | later |
| T8 | 1260-1265 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T9 | 1260-1265 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
FSU-PRGE
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 124-213 | protein | denotes | UDP-N-acetylgalactosamine: globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase |
| T2 | 685-688 | protein | denotes | ABO |
| T3 | 743-746 | protein | denotes | IgM |
| T4 | 751-754 | protein | denotes | IgG |
| T5 | 955-990 | protein | denotes | 3-beta-galactosyltransferase family |
| T6 | 1018-1106 | protein | denotes | UDP-N-acetylgalactosamine:globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase |
| T7 | 1110-1128 | protein | denotes | globoside synthase |
| T8 | 1551-1562 | protein | denotes | transferase |
| T9 | 1606-1624 | protein | denotes | globoside synthase |
PIR-corpus2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 124-172 | protein | denotes | UDP-N-acetylgalactosamine: globotriaosylceramide |
| T2 | 597-614 | protein | denotes | cellular receptor |
| T3 | 743-746 | protein | denotes | IgM |
| T4 | 751-754 | protein | denotes | IgG |
| T5 | 955-983 | protein | denotes | 3-beta-galactosyltransferase |
| T6 | 1018-1065 | protein | denotes | UDP-N-acetylgalactosamine:globotriaosylceramide |
| T7 | 1110-1128 | protein | denotes | globoside synthase |
| T8 | 1551-1562 | protein | denotes | transferase |
| T9 | 1606-1624 | protein | denotes | globoside synthase |
PIR-corpus1
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 606-614 | protein | denotes | receptor |
| T2 | 717-727 | protein | denotes | antibodies |
| T3 | 729-735 | protein | denotes | anti-P |
| T4 | 1018-1065 | protein | denotes | UDP-N-acetylgalactosamine:globotriaosylceramide |
| T5 | 1110-1128 | protein | denotes | globoside synthase |
| T6 | 1551-1562 | protein | denotes | transferase |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 657-673 | OrganismTaxon | denotes | Escherichia coli | 562 |
Glycosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 23-32 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | globoside | http://www.glycoepitope.jp/epitopes/EP0073 |
| T2 | 582-591 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | globoside | http://www.glycoepitope.jp/epitopes/EP0073 |
| T3 | 1110-1119 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | globoside | http://www.glycoepitope.jp/epitopes/EP0073 |
| T4 | 1606-1615 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | globoside | http://www.glycoepitope.jp/epitopes/EP0073 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 48-53 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T2 | 296-301 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T3 | 373-378 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
| T4 | 481-492 | Body_part | denotes | erythrocyte | http://purl.obolibrary.org/obo/CL_0000232 |
| T5 | 1260-1265 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 48-53 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T3 | 296-301 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T5 | 373-378 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
| T7 | 995-1000 | Body_part | denotes | later | http://purl.obolibrary.org/obo/MAT_0000488 |
| T8 | 1260-1265 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |