PubMed:11980897
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 81-90 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T2 | 202-211 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T3 | 290-299 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T4 | 430-438 | https://acgg.asia/db/ggdb/info/gg062 | denotes | ST8Sia I |
| T5 | 458-466 | https://acgg.asia/db/ggdb/info/gg066 | denotes | ST8Sia V |
| T6 | 552-561 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T7 | 909-918 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T8 | 934-943 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T9 | 1063-1072 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T10 | 1130-1139 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T11 | 1289-1298 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T12 | 1373-1382 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 440-443 | Glycan_Motif | denotes | GD3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G98544DH|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81928IQ |
| T3 | 468-472 | Glycan_Motif | denotes | GD1c | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G81983KG |
| T4 | 474-478 | Glycan_Motif | denotes | GT1a | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93468NI|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68110IF |
| T6 | 480-484 | Glycan_Motif | denotes | GQ1b | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G18625KA|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G17077FL |
| T8 | 490-493 | Glycan_Motif | denotes | GT3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G93899SO|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G33570YF |
| T10 | 844-859 | Glycan_Motif | denotes | polysialic acid | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00065MO |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 81-90 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T2 | 202-211 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T3 | 290-299 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T4 | 430-438 | https://acgg.asia/db/ggdb/info/gg062 | denotes | ST8Sia I |
| T5 | 458-466 | https://acgg.asia/db/ggdb/info/gg066 | denotes | ST8Sia V |
| T6 | 552-561 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T7 | 909-918 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T8 | 934-943 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T9 | 1063-1072 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T10 | 1130-1139 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T11 | 1289-1298 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| T12 | 1373-1382 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans. |
| T2 | 119-273 | Sentence | denotes | A novel member of the mouse alpha2,8-sialyltransferase (ST8Sia) family, designated ST8Sia VI, was identified by BLAST analysis of expressed sequence tags. |
| T3 | 274-519 | Sentence | denotes | The sequence of ST8Sia VI encodes a protein of 398 amino acids and shows 42.0 and 38.3% amino acid sequence identities to mouse alpha2,8-sialyltransferases ST8Sia I (GD3 synthase) and ST8Sia V (GD1c, GT1a, GQ1b, and GT3 synthases), respectively. |
| T4 | 520-770 | Sentence | denotes | The recombinant soluble form of ST8Sia VI expressed in COS-7 cells exhibited alpha2,8-sialyltransferase activity toward both glycolipids and glycoproteins that have the NeuAcalpha2,3(6)Gal sequence at the nonreducing end of their carbohydrate groups. |
| T5 | 771-871 | Sentence | denotes | This enzyme formed NeuAcalpha2,8NeuAc structures, but not oligosialic or polysialic acid structures. |
| T6 | 872-998 | Sentence | denotes | Analysis of the fetuin sialylated by ST8Sia VI indicated that ST8Sia VI prefers O-glycans to N-glycans as acceptor substrates. |
| T7 | 999-1129 | Sentence | denotes | Substrate specificities and kinetic properties also showed that ST8Sia VI prefers O-glycans to glycolipids as acceptor substrates. |
| T8 | 1130-1350 | Sentence | denotes | ST8Sia VI also exhibited activity toward oligosaccharides such as sialyllactose and sialyllactosamine, and the structure of the minimal acceptor substrate for ST8Sia VI was determined as the NeuAcalpha2,3(6)Gal sequence. |
| T9 | 1351-1508 | Sentence | denotes | The expression of the ST8Sia VI gene was ubiquitous, and the highest expression was observed in kidney, with three major transcripts of 8.2, 3.8, and 2.7 kb. |
| T10 | 1509-1617 | Sentence | denotes | This is the first report of a mammalian alpha2,8-sialyltransferase that sialylates O-glycans preferentially. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 440-443 | https://glytoucan.org/Structures/Glycans/G81928IQ | denotes | GD3 |
| T2 | 440-443 | https://glytoucan.org/Structures/Glycans/G98544DH | denotes | GD3 |
| T3 | 468-472 | https://glytoucan.org/Structures/Glycans/G81983KG | denotes | GD1c |
| T4 | 474-478 | https://glytoucan.org/Structures/Glycans/G68110IF | denotes | GT1a |
| T5 | 474-478 | https://glytoucan.org/Structures/Glycans/G93468NI | denotes | GT1a |
| T6 | 480-484 | https://glytoucan.org/Structures/Glycans/G17077FL | denotes | GQ1b |
| T7 | 480-484 | https://glytoucan.org/Structures/Glycans/G18625KA | denotes | GQ1b |
| T8 | 490-493 | https://glytoucan.org/Structures/Glycans/G33570YF | denotes | GT3 |
| T9 | 490-493 | https://glytoucan.org/Structures/Glycans/G93899SO | denotes | GT3 |
| T10 | 844-859 | https://glytoucan.org/Structures/Glycans/G00065MO | denotes | polysialic acid |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 474-478 | http://www.glycoepitope.jp/epitopes/EP0066 | denotes | GT1a |
| T2 | 480-484 | http://www.glycoepitope.jp/epitopes/EP0069 | denotes | GQ1b |
| T3 | 490-493 | http://www.glycoepitope.jp/epitopes/EP0070 | denotes | GT3 |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1447-1453 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 81-90 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T2 | 191-201 | url | denotes | designated |
| PD-GlycoGenes20190927-B_T3 | 202-211 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T4 | 290-299 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T5 | 430-438 | https://acgg.asia/db/ggdb/info/gg062 | denotes | ST8Sia I |
| PD-GlycoGenes20190927-B_T6 | 458-466 | https://acgg.asia/db/ggdb/info/gg066 | denotes | ST8Sia V |
| PD-GlycoGenes20190927-B_T7 | 552-561 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T8 | 909-918 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T9 | 934-943 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T10 | 1063-1072 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T11 | 1130-1139 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T12 | 1289-1298 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
| PD-GlycoGenes20190927-B_T13 | 1373-1382 | https://acgg.asia/db/ggdb/info/gg067 | denotes | ST8Sia VI |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 440-443 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T2 | 474-478 | Glycan | denotes | GT1a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G68110IF |
| T3 | 480-484 | Glycan | denotes | GQ1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G18625KA |
| T4 | 490-493 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1447-1453 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 440-443 | Glycan | denotes | GD3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G98544DH |
| T2 | 474-478 | Glycan | denotes | GT1a | https://api.glycosmos.org/wurcs2image/latest/png/binary/G68110IF |
| T3 | 480-484 | Glycan | denotes | GQ1b | https://api.glycosmos.org/wurcs2image/latest/png/binary/G18625KA |
| T4 | 490-493 | Glycan | denotes | GT3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G93899SO |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 474-478 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT1a | http://www.glycoepitope.jp/epitopes/EP0066 |
| T2 | 480-484 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T3 | 490-493 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 474-478 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT1a | http://www.glycoepitope.jp/epitopes/EP0066 |
| T2 | 480-484 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GQ1b | http://www.glycoepitope.jp/epitopes/EP0069 |
| T3 | 490-493 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | GT3 | http://www.glycoepitope.jp/epitopes/EP0070 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 141-146 | Organism | denotes | mouse | 10088|10090 |
| T3 | 396-401 | Organism | denotes | mouse | 10088|10090 |
| T5 | 1539-1548 | Organism | denotes | mammalian | 40674 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-118 | Sentence | denotes | Molecular cloning and expression of a sixth type of alpha 2,8-sialyltransferase (ST8Sia VI) that sialylates O-glycans. |
| T2 | 119-273 | Sentence | denotes | A novel member of the mouse alpha2,8-sialyltransferase (ST8Sia) family, designated ST8Sia VI, was identified by BLAST analysis of expressed sequence tags. |
| T3 | 274-519 | Sentence | denotes | The sequence of ST8Sia VI encodes a protein of 398 amino acids and shows 42.0 and 38.3% amino acid sequence identities to mouse alpha2,8-sialyltransferases ST8Sia I (GD3 synthase) and ST8Sia V (GD1c, GT1a, GQ1b, and GT3 synthases), respectively. |
| T4 | 520-770 | Sentence | denotes | The recombinant soluble form of ST8Sia VI expressed in COS-7 cells exhibited alpha2,8-sialyltransferase activity toward both glycolipids and glycoproteins that have the NeuAcalpha2,3(6)Gal sequence at the nonreducing end of their carbohydrate groups. |
| T5 | 771-871 | Sentence | denotes | This enzyme formed NeuAcalpha2,8NeuAc structures, but not oligosialic or polysialic acid structures. |
| T6 | 872-998 | Sentence | denotes | Analysis of the fetuin sialylated by ST8Sia VI indicated that ST8Sia VI prefers O-glycans to N-glycans as acceptor substrates. |
| T7 | 999-1129 | Sentence | denotes | Substrate specificities and kinetic properties also showed that ST8Sia VI prefers O-glycans to glycolipids as acceptor substrates. |
| T8 | 1130-1350 | Sentence | denotes | ST8Sia VI also exhibited activity toward oligosaccharides such as sialyllactose and sialyllactosamine, and the structure of the minimal acceptor substrate for ST8Sia VI was determined as the NeuAcalpha2,3(6)Gal sequence. |
| T9 | 1351-1508 | Sentence | denotes | The expression of the ST8Sia VI gene was ubiquitous, and the highest expression was observed in kidney, with three major transcripts of 8.2, 3.8, and 2.7 kb. |
| T10 | 1509-1617 | Sentence | denotes | This is the first report of a mammalian alpha2,8-sialyltransferase that sialylates O-glycans preferentially. |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1447-1453 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 1447-1453 | Body_part | denotes | kidney | FMA:7203 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1447-1453 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 141-146 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T3 | 396-401 | OrganismTaxon | denotes | mouse | 10088|10090 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 1447-1453 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |