PubMed:11933682 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/11933682","sourcedb":"PubMed","sourceid":"11933682","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/11933682","text":"ICAM-1 in maternal serum and amniotic fluid as an early marker of preeclampsia and IUGR.\nOBJECTIVE: To determine if plasma and amniotic fluid levels of intercellular adhesion molecule-1 (ICAM-1) at 16 weeks' gestation could be predictive of preeclampsia or intrauterine growth retardation (IUGR).\nSTUDY DESIGN: A retrospective analysis was undertaken in 44 serum samples stored for Down's syndrome screening at 16 weeks' gestation and 44 amniotic fluid samples obtained by midtrimester amniocentesis.\nRESULTS: No significant difference was found between women who subsequently developed preeclampsia or IUGR and the control group.\nCONCLUSION: This study failed to demonstrate that ICAM-1 may be an early serum marker of preeclampsia or an amniotic fluid marker of 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