PubMed:11821425
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 158-164 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
| T2 | 193-199 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
| T3 | 453-459 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
| T4 | 475-481 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
| T5 | 1338-1344 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
| T6 | 1573-1579 | Glycan_Motif | denotes | core 3 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-188 | Sentence | denotes | Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. |
| T2 | 189-470 | Sentence | denotes | The core 3 structure of the O-glycan, GlcNAcbeta1-3GalNAcalpha1-serine/threonine, an important precursor in the biosynthesis of mucin-type glycoproteins, is synthesized by UDP-N-acetylglucosamine:GalNAc-peptide beta1,3-N- acetylglucosaminyltransferase (beta3Gn-T; core 3 synthase). |
| T3 | 471-604 | Sentence | denotes | The core 3 structure is restricted in its occurrence to mucins from specific tissues such as the stomach, small intestine, and colon. |
| T4 | 605-713 | Sentence | denotes | A partial sequence encoding a novel member of the human beta3Gn-T family was found in one of the data bases. |
| T5 | 714-781 | Sentence | denotes | We cloned a complementary DNA of this gene and named it beta3Gn-T6. |
| T6 | 782-922 | Sentence | denotes | The putative amino acid sequence of beta3Gn-T6 retains the beta3Gn-T motifs and is predicted to comprise a typical type II membrane protein. |
| T7 | 923-1073 | Sentence | denotes | The soluble form of beta3Gn-T6 expressed in insect cells showed beta3Gn-T activity toward GalNAcalpha-p-nitrophenyl and GalNAcalpha1-serine/threonine. |
| T8 | 1074-1355 | Sentence | denotes | The beta1,3-linkage between GlcNAc and GalNAc of the enzyme reaction product was confirmed by high performance liquid chromatography and NMR analyses. beta3Gn-T6 effectively transferred a GlcNAc to the GalNAc residue on MUC1 mucin, resulting in the synthesis of a core 3 structure. |
| T9 | 1356-1505 | Sentence | denotes | Real time PCR analysis revealed that the beta3Gn-T6 transcript was restricted in its distribution, mainly to the stomach, colon, and small intestine. |
| T10 | 1506-1681 | Sentence | denotes | We concluded that beta3Gn-T6 is the most logical candidate for the core 3 synthase, which plays an important role in the synthesis of mucin-type O-glycans in digestive organs. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 568-575 | http://purl.obolibrary.org/obo/MAT_0000051 | denotes | stomach |
| T2 | 577-592 | http://purl.obolibrary.org/obo/MAT_0000047 | denotes | small intestine |
| T3 | 583-592 | http://purl.obolibrary.org/obo/MAT_0000043 | denotes | intestine |
| T4 | 598-603 | http://purl.obolibrary.org/obo/MAT_0000526 | denotes | colon |
| T5 | 1469-1476 | http://purl.obolibrary.org/obo/MAT_0000051 | denotes | stomach |
| T6 | 1478-1483 | http://purl.obolibrary.org/obo/MAT_0000526 | denotes | colon |
| T7 | 1489-1504 | http://purl.obolibrary.org/obo/MAT_0000047 | denotes | small intestine |
| T8 | 1495-1504 | http://purl.obolibrary.org/obo/MAT_0000043 | denotes | intestine |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 442-451 | https://acgg.asia/db/ggdb/info/gg116 | denotes | beta3Gn-T |
| PD-GlycoGenes20190927-B_T2 | 661-670 | https://acgg.asia/db/ggdb/info/gg116 | denotes | beta3Gn-T |
| PD-GlycoGenes20190927-B_T3 | 841-850 | https://acgg.asia/db/ggdb/info/gg116 | denotes | beta3Gn-T |
| PD-GlycoGenes20190927-B_T4 | 902-904 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
| PD-GlycoGenes20190927-B_T5 | 987-996 | https://acgg.asia/db/ggdb/info/gg116 | denotes | beta3Gn-T |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 1102-1108 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T2 | 1262-1268 | chem:24139 | denotes | GlcNAc |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 568-575 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/MAT_0000051 |
| T2 | 577-592 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
| T3 | 598-603 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/MAT_0000526 |
| T4 | 1469-1476 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/MAT_0000051 |
| T5 | 1478-1483 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/MAT_0000526 |
| T6 | 1489-1504 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 158-164 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T2 | 193-199 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T3 | 453-459 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T4 | 475-481 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T5 | 1113-1119 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T6 | 1276-1282 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T7 | 1338-1344 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T8 | 1573-1579 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 655-660 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 568-575 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/UBERON_0000945 |
| T2 | 577-592 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T3 | 598-603 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
| T4 | 905-913 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T7 | 1469-1476 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/UBERON_0000945 |
| T8 | 1478-1483 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
| T9 | 1489-1504 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T10 | 1664-1680 | Body_part | denotes | digestive organs | http://purl.obolibrary.org/obo/UBERON_0013765 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 568-575 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/MAT_0000051 |
| T2 | 577-592 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
| T3 | 598-603 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/MAT_0000526 |
| T4 | 1469-1476 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/MAT_0000051 |
| T5 | 1478-1483 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/MAT_0000526 |
| T6 | 1489-1504 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/MAT_0000047 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-188 | Sentence | denotes | Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. |
| T2 | 189-470 | Sentence | denotes | The core 3 structure of the O-glycan, GlcNAcbeta1-3GalNAcalpha1-serine/threonine, an important precursor in the biosynthesis of mucin-type glycoproteins, is synthesized by UDP-N-acetylglucosamine:GalNAc-peptide beta1,3-N- acetylglucosaminyltransferase (beta3Gn-T; core 3 synthase). |
| T3 | 471-604 | Sentence | denotes | The core 3 structure is restricted in its occurrence to mucins from specific tissues such as the stomach, small intestine, and colon. |
| T4 | 605-713 | Sentence | denotes | A partial sequence encoding a novel member of the human beta3Gn-T family was found in one of the data bases. |
| T5 | 714-781 | Sentence | denotes | We cloned a complementary DNA of this gene and named it beta3Gn-T6. |
| T6 | 782-922 | Sentence | denotes | The putative amino acid sequence of beta3Gn-T6 retains the beta3Gn-T motifs and is predicted to comprise a typical type II membrane protein. |
| T7 | 923-1073 | Sentence | denotes | The soluble form of beta3Gn-T6 expressed in insect cells showed beta3Gn-T activity toward GalNAcalpha-p-nitrophenyl and GalNAcalpha1-serine/threonine. |
| T8 | 1074-1355 | Sentence | denotes | The beta1,3-linkage between GlcNAc and GalNAc of the enzyme reaction product was confirmed by high performance liquid chromatography and NMR analyses. beta3Gn-T6 effectively transferred a GlcNAc to the GalNAc residue on MUC1 mucin, resulting in the synthesis of a core 3 structure. |
| T9 | 1356-1505 | Sentence | denotes | Real time PCR analysis revealed that the beta3Gn-T6 transcript was restricted in its distribution, mainly to the stomach, colon, and small intestine. |
| T10 | 1506-1681 | Sentence | denotes | We concluded that beta3Gn-T6 is the most logical candidate for the core 3 synthase, which plays an important role in the synthesis of mucin-type O-glycans in digestive organs. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-188 | Sentence | denotes | Molecular cloning and characterization of a novel UDP-GlcNAc:GalNAc-peptide beta1,3-N-acetylglucosaminyltransferase (beta 3Gn-T6), an enzyme synthesizing the core 3 structure of O-glycans. |
| T2 | 189-470 | Sentence | denotes | The core 3 structure of the O-glycan, GlcNAcbeta1-3GalNAcalpha1-serine/threonine, an important precursor in the biosynthesis of mucin-type glycoproteins, is synthesized by UDP-N-acetylglucosamine:GalNAc-peptide beta1,3-N- acetylglucosaminyltransferase (beta3Gn-T; core 3 synthase). |
| T3 | 471-604 | Sentence | denotes | The core 3 structure is restricted in its occurrence to mucins from specific tissues such as the stomach, small intestine, and colon. |
| T4 | 605-713 | Sentence | denotes | A partial sequence encoding a novel member of the human beta3Gn-T family was found in one of the data bases. |
| T5 | 714-781 | Sentence | denotes | We cloned a complementary DNA of this gene and named it beta3Gn-T6. |
| T6 | 782-922 | Sentence | denotes | The putative amino acid sequence of beta3Gn-T6 retains the beta3Gn-T motifs and is predicted to comprise a typical type II membrane protein. |
| T7 | 923-1073 | Sentence | denotes | The soluble form of beta3Gn-T6 expressed in insect cells showed beta3Gn-T activity toward GalNAcalpha-p-nitrophenyl and GalNAcalpha1-serine/threonine. |
| T8 | 1074-1355 | Sentence | denotes | The beta1,3-linkage between GlcNAc and GalNAc of the enzyme reaction product was confirmed by high performance liquid chromatography and NMR analyses. beta3Gn-T6 effectively transferred a GlcNAc to the GalNAc residue on MUC1 mucin, resulting in the synthesis of a core 3 structure. |
| T9 | 1356-1505 | Sentence | denotes | Real time PCR analysis revealed that the beta3Gn-T6 transcript was restricted in its distribution, mainly to the stomach, colon, and small intestine. |
| T10 | 1506-1681 | Sentence | denotes | We concluded that beta3Gn-T6 is the most logical candidate for the core 3 synthase, which plays an important role in the synthesis of mucin-type O-glycans in digestive organs. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 158-164 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T2 | 193-199 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T3 | 453-459 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T4 | 475-481 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T5 | 1113-1119 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T6 | 1276-1282 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T7 | 1338-1344 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
| T8 | 1573-1579 | Glycan | denotes | core 3 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00035MO |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 655-660 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 568-575 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/UBERON_0000945 |
| T2 | 577-592 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T3 | 598-603 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
| T4 | 905-913 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T7 | 1469-1476 | Body_part | denotes | stomach | http://purl.obolibrary.org/obo/UBERON_0000945 |
| T8 | 1478-1483 | Body_part | denotes | colon | http://purl.obolibrary.org/obo/UBERON_0001155 |
| T9 | 1489-1504 | Body_part | denotes | small intestine | http://purl.obolibrary.org/obo/UBERON_0002108 |
| T10 | 1664-1680 | Body_part | denotes | digestive organs | http://purl.obolibrary.org/obo/UBERON_0013765 |