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PubMed:11788602 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 42-53 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T2 143-154 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T3 228-235 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T5 311-322 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T6 544-555 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T7 682-703 Glycan_Motif denotes N-acetylgalactosamine https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB
T8 757-768 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T9 790-801 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T10 1058-1069 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T11 1158-1169 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T12 1248-1259 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T13 1358-1369 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T14 1390-1397 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO
T16 1565-1576 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T17 1733-1744 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T18 1874-1885 Glycan_Motif denotes chondroitin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT
T19 1929-1936 Glycan_Motif denotes heparin https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54161DR|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00021MO

sentences

Id Subject Object Predicate Lexical cue
T1 0-252 Sentence denotes Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
T2 253-479 Sentence denotes Based on sequence homology with the recently cloned human chondroitin synthase, we identified a novel beta1,4-N-acetylgalactosaminyltransferase, which consisted of 532 amino acids with a type II transmembrane protein topology.
T3 480-565 Sentence denotes The amino acid sequence displayed 27% identity to that of human chondroitin synthase.
T4 566-1078 Sentence denotes The expression of a soluble form of the protein in COS-1 cells produced an active enzyme, which transferred beta1,4-N-acetylgalactosamine (GalNAc) from UDP-[(3)H]GalNAc not only to a polymer chondroitin representing growing chondroitin chains (beta-GalNAc transferase II activity) but also to GlcUAbeta1--3Galbeta1-O-C(2)H(4)NH-benzyloxycarbonyl, a synthetic substrate for beta-GalNAc transferase I that transfers the first GalNAc to the core tetrasaccharide in the protein linkage region of chondroitin sulfate.
T5 1079-1421 Sentence denotes Hence, the enzyme is involved in the biosynthetic initiation and elongation of chondroitin sulfate and is the key enzyme responsible for the selective chain assembly of chondroitin/dermatan sulfate on the linkage region tetrasaccharide common to various proteoglycans containing chondroitin/dermatan sulfate or heparin/heparan sulfate chains.
T6 1422-1523 Sentence denotes The coding region of this enzyme was divided into seven discrete exons and localized to chromosome 8.
T7 1524-1754 Sentence denotes Northern blot analysis revealed that the chondroitin GalNAc transferase gene exhibited a ubiquitous but markedly differential expression in human tissues and that the expression pattern was similar to that of chondroitin synthase.
T8 1755-1953 Sentence denotes Thus, more than two distinct enzymes forming the novel gene family are required for chain initiation and elongation in chondroitin/dermatan sulfate as in the biosynthesis of heparin/heparan sulfate.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 42-53 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T2 143-154 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T3 228-235 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T4 228-235 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T5 311-322 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T6 544-555 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T7 682-703 https://glytoucan.org/Structures/Glycans/G27025MB denotes N-acetylgalactosamine
T8 757-768 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T9 790-801 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T10 1058-1069 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T11 1158-1169 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T12 1248-1259 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T13 1358-1369 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T14 1390-1397 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T15 1390-1397 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin
T16 1565-1576 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T17 1733-1744 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T18 1874-1885 https://glytoucan.org/Structures/Glycans/G43702JT denotes chondroitin
T19 1929-1936 https://glytoucan.org/Structures/Glycans/G00021MO denotes heparin
T20 1929-1936 https://glytoucan.org/Structures/Glycans/G54161DR denotes heparin

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 42-53 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T2 143-154 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T3 236-251 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T4 311-322 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T5 544-555 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T6 757-768 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T7 790-801 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T8 1058-1069 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T9 1158-1169 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T10 1248-1259 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T11 1358-1369 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T12 1398-1413 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate
T13 1565-1576 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T14 1733-1744 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T15 1874-1885 http://www.glycoepitope.jp/epitopes/EP0081 denotes chondroitin
T16 1937-1952 http://www.glycoepitope.jp/epitopes/EP0086 denotes heparan sulfate

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 42-53 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T2 143-154 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 311-322 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T4 544-555 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T5 705-711 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 728-734 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 757-768 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T8 790-801 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T9 815-821 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T10 944-950 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T11 990-996 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T12 1058-1069 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T13 1158-1169 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T14 1248-1259 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T15 1358-1369 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T16 1565-1576 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T17 1577-1583 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T18 1733-1744 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T19 1874-1885 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T25 236-251 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T39 1398-1413 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T22 1937-1952 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 42-53 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T2 143-154 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T3 311-322 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T4 544-555 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T5 705-711 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T6 728-734 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T7 757-768 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T8 790-801 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T9 815-821 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T10 944-950 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T11 990-996 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T12 1058-1069 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T13 1158-1169 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T14 1248-1259 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T15 1358-1369 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T16 1565-1576 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T17 1577-1583 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T18 1733-1744 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T19 1874-1885 Glycan denotes chondroitin https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT
T22 236-251 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T36 1398-1413 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW
T41 1937-1952 Glycan denotes heparan sulfate https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW

GlyCosmos15-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1510-1520 Body_part denotes chromosome http://purl.obolibrary.org/obo/GO_0005694

GlyCosmos15-Taxon

Id Subject Object Predicate Lexical cue db_id
T1 36-41 Organism denotes human 9606
T2 305-310 Organism denotes human 9606
T3 538-543 Organism denotes human 9606
T4 1664-1669 Organism denotes human 9606

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-252 Sentence denotes Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate.
T2 253-479 Sentence denotes Based on sequence homology with the recently cloned human chondroitin synthase, we identified a novel beta1,4-N-acetylgalactosaminyltransferase, which consisted of 532 amino acids with a type II transmembrane protein topology.
T3 480-565 Sentence denotes The amino acid sequence displayed 27% identity to that of human chondroitin synthase.
T4 566-1078 Sentence denotes The expression of a soluble form of the protein in COS-1 cells produced an active enzyme, which transferred beta1,4-N-acetylgalactosamine (GalNAc) from UDP-[(3)H]GalNAc not only to a polymer chondroitin representing growing chondroitin chains (beta-GalNAc transferase II activity) but also to GlcUAbeta1--3Galbeta1-O-C(2)H(4)NH-benzyloxycarbonyl, a synthetic substrate for beta-GalNAc transferase I that transfers the first GalNAc to the core tetrasaccharide in the protein linkage region of chondroitin sulfate.
T5 1079-1421 Sentence denotes Hence, the enzyme is involved in the biosynthetic initiation and elongation of chondroitin sulfate and is the key enzyme responsible for the selective chain assembly of chondroitin/dermatan sulfate on the linkage region tetrasaccharide common to various proteoglycans containing chondroitin/dermatan sulfate or heparin/heparan sulfate chains.
T6 1422-1523 Sentence denotes The coding region of this enzyme was divided into seven discrete exons and localized to chromosome 8.
T7 1524-1754 Sentence denotes Northern blot analysis revealed that the chondroitin GalNAc transferase gene exhibited a ubiquitous but markedly differential expression in human tissues and that the expression pattern was similar to that of chondroitin synthase.
T8 1755-1953 Sentence denotes Thus, more than two distinct enzymes forming the novel gene family are required for chain initiation and elongation in chondroitin/dermatan sulfate as in the biosynthesis of heparin/heparan sulfate.

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 42-53 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T2 143-154 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 236-251 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T4 311-322 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T5 544-555 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T6 757-768 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T7 790-801 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T8 1058-1069 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T9 1158-1169 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T10 1248-1259 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T11 1358-1369 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T12 1398-1413 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T13 1565-1576 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T14 1733-1744 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T15 1874-1885 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T16 1937-1952 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086

GlyCosmos15-FMA

Id Subject Object Predicate Lexical cue db_id
T1 1510-1520 Body_part denotes chromosome FMA:67093
T2 1670-1677 Body_part denotes tissues FMA:9637

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 36-41 OrganismTaxon denotes human 9606
T2 305-310 OrganismTaxon denotes human 9606
T3 538-543 OrganismTaxon denotes human 9606
T4 1664-1669 OrganismTaxon denotes human 9606

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 42-53 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T2 143-154 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T3 236-251 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T4 311-322 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T5 544-555 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T6 757-768 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T7 790-801 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T8 1058-1069 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T9 1158-1169 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T10 1248-1259 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T11 1358-1369 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T12 1398-1413 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086
T13 1565-1576 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T14 1733-1744 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T15 1874-1885 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes chondroitin http://www.glycoepitope.jp/epitopes/EP0081
T16 1937-1952 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes heparan sulfate http://www.glycoepitope.jp/epitopes/EP0086

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 448-461 Body_part denotes transmembrane http://purl.obolibrary.org/obo/GO_0016020
T2 1510-1520 Body_part denotes chromosome http://purl.obolibrary.org/obo/GO_0005694