Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-87 |
Sentence |
denotes |
Cytogenetic-clinicopathologic correlations in rhabdomyosarcoma: a report of five cases. |
TextSentencer_T2 |
88-195 |
Sentence |
denotes |
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children younger than the age of 15 years. |
TextSentencer_T3 |
196-349 |
Sentence |
denotes |
Histologically, RMS can be subdivided into two major subtypes; embryonal (E-RMS) and alveolar (A-RMS) rhabdomyosarcoma, with E-RMS being the more common. |
TextSentencer_T4 |
350-533 |
Sentence |
denotes |
Although cytogenetic and molecular genetic findings have been reported extensively for RMS, clinicopathologic-genetic correlations among these tumors have not been reported in detail. |
TextSentencer_T5 |
534-806 |
Sentence |
denotes |
In this report, we correlate the cytogenetic findings, including fluorescence in situ hybridization and spectral karyotyping, with pathologic findings and outcome for five RMS, including two A-RMS, one E-RMS, one botryoid RMS, and one anaplastic nonclassified RMS (N-RMS). |
TextSentencer_T6 |
807-1028 |
Sentence |
denotes |
The findings in A-RMS and E-RMS generally were consistent with previous reports; however, gain of chromosome 7 in A-RMS and gain of chromosome 9 segments in E-RMS observed here have seldom been reported in the literature. |
TextSentencer_T7 |
1029-1117 |
Sentence |
denotes |
Importantly, the botryoid RMS had a cytogenetic profile similar to other types of E-RMS. |
TextSentencer_T8 |
1118-1308 |
Sentence |
denotes |
An add(11)(q21) observed in this tumor, together with a t(8;11)(q12 approximately 13;q21) reported previously, indicates that 11q21 rearrangements may be nonrandomly related to botryoid RMS. |
TextSentencer_T9 |
1309-1475 |
Sentence |
denotes |
In addition, the N-RMS expressed a cytogenetic pattern similar to that observed in E-RMS, thus providing genetic evidence that anaplastic N-RMS is a variant of E-RMS. |
TextSentencer_T10 |
1476-1616 |
Sentence |
denotes |
Finally, these cases provide cogent evidence for the diagnostic and prognostic significance of the pathologic-genetic classification of RMS. |
T1 |
0-87 |
Sentence |
denotes |
Cytogenetic-clinicopathologic correlations in rhabdomyosarcoma: a report of five cases. |
T2 |
88-195 |
Sentence |
denotes |
Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children younger than the age of 15 years. |
T3 |
196-349 |
Sentence |
denotes |
Histologically, RMS can be subdivided into two major subtypes; embryonal (E-RMS) and alveolar (A-RMS) rhabdomyosarcoma, with E-RMS being the more common. |
T4 |
350-533 |
Sentence |
denotes |
Although cytogenetic and molecular genetic findings have been reported extensively for RMS, clinicopathologic-genetic correlations among these tumors have not been reported in detail. |
T5 |
534-806 |
Sentence |
denotes |
In this report, we correlate the cytogenetic findings, including fluorescence in situ hybridization and spectral karyotyping, with pathologic findings and outcome for five RMS, including two A-RMS, one E-RMS, one botryoid RMS, and one anaplastic nonclassified RMS (N-RMS). |
T6 |
807-1028 |
Sentence |
denotes |
The findings in A-RMS and E-RMS generally were consistent with previous reports; however, gain of chromosome 7 in A-RMS and gain of chromosome 9 segments in E-RMS observed here have seldom been reported in the literature. |
T7 |
1029-1117 |
Sentence |
denotes |
Importantly, the botryoid RMS had a cytogenetic profile similar to other types of E-RMS. |
T8 |
1118-1308 |
Sentence |
denotes |
An add(11)(q21) observed in this tumor, together with a t(8;11)(q12 approximately 13;q21) reported previously, indicates that 11q21 rearrangements may be nonrandomly related to botryoid RMS. |
T9 |
1309-1475 |
Sentence |
denotes |
In addition, the N-RMS expressed a cytogenetic pattern similar to that observed in E-RMS, thus providing genetic evidence that anaplastic N-RMS is a variant of E-RMS. |
T10 |
1476-1616 |
Sentence |
denotes |
Finally, these cases provide cogent evidence for the diagnostic and prognostic significance of the pathologic-genetic classification of RMS. |