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PubMed:11703582 JSONTXT

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performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1178-1187 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extension
PD-UBERON-AE-B_T2 1374-1383 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extension

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
11703582-1#9#28#gene80350 110-129 gene80350 denotes apolipoprotein A-II
11703582-1#9#28#gene336 110-129 gene336 denotes apolipoprotein A-II
11703582-1#30#37#gene80350 131-138 gene80350 denotes apoA-II
11703582-1#30#37#gene336 131-138 gene336 denotes apoA-II
11703582-1#179#186#gene80350 280-287 gene80350 denotes apoA-II
11703582-1#179#186#gene336 280-287 gene336 denotes apoA-II
11703582-1#298#305#gene80350 399-406 gene80350 denotes apoA-II
11703582-1#298#305#gene336 399-406 gene336 denotes apoA-II
11703582-1#229#246#diseaseC0268382 330-347 diseaseC0268382 denotes renal amyloidosis
11703582-10#26#33#gene80350 1448-1455 gene80350 denotes apoA-II
11703582-10#26#33#gene336 1448-1455 gene336 denotes apoA-II
11703582-10#34#45#diseaseC0002726 1456-1467 diseaseC0002726 denotes amyloidosis
9#28#gene80350229#246#diseaseC0268382 11703582-1#9#28#gene80350 11703582-1#229#246#diseaseC0268382 associated_with apolipoprotein A-II,renal amyloidosis
9#28#gene336229#246#diseaseC0268382 11703582-1#9#28#gene336 11703582-1#229#246#diseaseC0268382 associated_with apolipoprotein A-II,renal amyloidosis
30#37#gene80350229#246#diseaseC0268382 11703582-1#30#37#gene80350 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
30#37#gene336229#246#diseaseC0268382 11703582-1#30#37#gene336 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
179#186#gene80350229#246#diseaseC0268382 11703582-1#179#186#gene80350 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
179#186#gene336229#246#diseaseC0268382 11703582-1#179#186#gene336 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
298#305#gene80350229#246#diseaseC0268382 11703582-1#298#305#gene80350 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
298#305#gene336229#246#diseaseC0268382 11703582-1#298#305#gene336 11703582-1#229#246#diseaseC0268382 associated_with apoA-II,renal amyloidosis
26#33#gene8035034#45#diseaseC0002726 11703582-10#26#33#gene80350 11703582-10#34#45#diseaseC0002726 associated_with apoA-II,amyloidosis
26#33#gene33634#45#diseaseC0002726 11703582-10#26#33#gene336 11703582-10#34#45#diseaseC0002726 associated_with apoA-II,amyloidosis

PubCasesHPO

Id Subject Object Predicate Lexical cue
TI1 0-17 HP:0001917 denotes Renal amyloidosis
AB1 151-162 HP:0011034 denotes amyloidosis
AB2 288-299 HP:0011034 denotes amyloidosis
AB3 330-347 HP:0001917 denotes renal amyloidosis
AB4 461-472 HP:0011034 denotes amyloidosis
AB5 531-542 HP:0000093 denotes proteinuria
AB6 697-714 HP:0001917 denotes renal amyloidosis
AB7 771-782 HP:0011034 denotes amyloidosis
AB8 1456-1467 HP:0011034 denotes amyloidosis

sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes Renal amyloidosis caused by a novel stop-codon mutation in the apolipoprotein A-II gene.
TextSentencer_T2 89-100 Sentence denotes BACKGROUND:
TextSentencer_T3 101-407 Sentence denotes Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.
TextSentencer_T4 408-487 Sentence denotes The mechanisms of amyloid formation in human apoA-II amyloidosis are not clear.
TextSentencer_T5 488-496 Sentence denotes METHODS:
TextSentencer_T6 497-580 Sentence denotes A 46-year-old Caucasian male with proteinuria noted at 42 years of age was studied.
TextSentencer_T7 581-635 Sentence denotes Renal biopsy revealed amyloid deposition in glomeruli.
TextSentencer_T8 636-741 Sentence denotes DNA analysis of genes known to be associated with hereditary renal amyloidosis revealed no abnormalities.
TextSentencer_T9 742-830 Sentence denotes To elucidate the type of his amyloidosis, apoA-II gene and plasma apoA-II were examined.
TextSentencer_T10 831-1014 Sentence denotes RESULTS: DNA analysis revealed heterozygosity for a G to C transversion at the second position of the stop-codon of apoA-II gene, suggesting a stop to serine substitution at codon 78.
TextSentencer_T11 1015-1206 Sentence denotes Western blot analysis and amino acid sequence analysis of the patient's plasma apoA-II showed both normal apoA-II and variant apoA-II with a 21-amino acid residue extension at the C-terminus.
TextSentencer_T12 1207-1219 Sentence denotes CONCLUSIONS:
TextSentencer_T13 1220-1421 Sentence denotes These results indicate that the patient's amyloid fibrils were derived from apoA-II and the amyloidogenesis is likely to be closely linked to the peptide extension at the C-terminus of variant apoA-II.
TextSentencer_T14 1422-1498 Sentence denotes The pathogenesis of human apoA-II amyloidosis is different from that of SAM.
T1 0-88 Sentence denotes Renal amyloidosis caused by a novel stop-codon mutation in the apolipoprotein A-II gene.
T2 89-100 Sentence denotes BACKGROUND:
T3 101-407 Sentence denotes Although apolipoprotein A-II (apoA-II) associated amyloidosis has been described in the senescent accelerated mouse (SAM) model of aging, so far there has been no report of human apoA-II amyloidosis except for a recent report of renal amyloidosis resulting from a stop-codon to glycine mutation of apoA-II.
T4 408-487 Sentence denotes The mechanisms of amyloid formation in human apoA-II amyloidosis are not clear.
T5 488-496 Sentence denotes METHODS:
T6 497-580 Sentence denotes A 46-year-old Caucasian male with proteinuria noted at 42 years of age was studied.
T7 581-635 Sentence denotes Renal biopsy revealed amyloid deposition in glomeruli.
T8 636-741 Sentence denotes DNA analysis of genes known to be associated with hereditary renal amyloidosis revealed no abnormalities.
T9 742-830 Sentence denotes To elucidate the type of his amyloidosis, apoA-II gene and plasma apoA-II were examined.
T10 831-1014 Sentence denotes RESULTS: DNA analysis revealed heterozygosity for a G to C transversion at the second position of the stop-codon of apoA-II gene, suggesting a stop to serine substitution at codon 78.
T11 1015-1206 Sentence denotes Western blot analysis and amino acid sequence analysis of the patient's plasma apoA-II showed both normal apoA-II and variant apoA-II with a 21-amino acid residue extension at the C-terminus.
T12 1207-1219 Sentence denotes CONCLUSIONS:
T13 1220-1421 Sentence denotes These results indicate that the patient's amyloid fibrils were derived from apoA-II and the amyloidogenesis is likely to be closely linked to the peptide extension at the C-terminus of variant apoA-II.
T14 1422-1498 Sentence denotes The pathogenesis of human apoA-II amyloidosis is different from that of SAM.

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1178-1187 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extension
PD-UBERON-AE-B_T2 1374-1383 http://purl.obolibrary.org/obo/UBERON_2000106 denotes extension

PubCasesORDO

Id Subject Object Predicate Lexical cue
AB1 686-714 ORDO:85450 denotes hereditary renal amyloidosis

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1448-1455 gene:80350 denotes apoA-II
T1 1456-1467 disease:C0002726 denotes amyloidosis
T2 1448-1455 gene:336 denotes apoA-II
T3 1456-1467 disease:C0002726 denotes amyloidosis
R1 T0 T1 associated_with apoA-II,amyloidosis
R2 T2 T3 associated_with apoA-II,amyloidosis