PubMed:11524432
Annnotations
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 624-632 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T2 | 757-765 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T3 | 833-841 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T4 | 1337-1345 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T5 | 1451-1459 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T6 | 1491-1497 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| T7 | 1591-1597 | https://acgg.asia/db/ggdb/info/gg012 | denotes | Pofut1 |
| T8 | 1662-1668 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| T9 | 1829-1837 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T10 | 1911-1919 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T11 | 1973-1981 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 624-632 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T2 | 757-765 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T3 | 833-841 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T4 | 1337-1345 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T5 | 1451-1459 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T6 | 1491-1497 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| T7 | 1591-1597 | https://acgg.asia/db/ggdb/info/gg012 | denotes | Pofut1 |
| T8 | 1662-1668 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| T9 | 1829-1837 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T10 | 1911-1919 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| T11 | 1973-1981 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 58-66 | Glycan_Motif | denotes | O-fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T2 | 116-122 | Glycan_Motif | denotes | fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T3 | 157-165 | Glycan_Motif | denotes | O-fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T4 | 279-287 | Glycan_Motif | denotes | O-Fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T5 | 382-390 | Glycan_Motif | denotes | O-fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T6 | 533-541 | Glycan_Motif | denotes | O-fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T7 | 587-593 | Glycan_Motif | denotes | fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
| T8 | 2159-2167 | Glycan_Motif | denotes | O-fucose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82576YO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-67 | Sentence | denotes | Modification of epidermal growth factor-like repeats with O-fucose. |
| T2 | 68-152 | Sentence | denotes | Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase. |
| T3 | 153-278 | Sentence | denotes | The O-fucose modification is found on epidermal growth factor-like repeats of a number of cell surface and secreted proteins. |
| T4 | 279-354 | Sentence | denotes | O-Fucose glycans play important roles in ligand-induced receptor signaling. |
| T5 | 355-511 | Sentence | denotes | For example, elongation of O-fucose on Notch by the beta1,3-N-acetylglucosaminyltransferase Fringe modulates the ability of Notch to respond to its ligands. |
| T6 | 512-698 | Sentence | denotes | The enzyme that adds O-fucose to epidermal growth factor-like repeats, GDP-fucose protein O-fucosyltransferase (O-FucT-1), was purified previously from Chinese hamster ovary (CHO) cells. |
| T7 | 699-766 | Sentence | denotes | Here we report the isolation of a cDNA that encodes human O-FucT-1. |
| T8 | 767-938 | Sentence | denotes | A probe deduced from N-terminal sequence analysis of purified CHO O-FucT-1 was used to screen a human heart cDNA library and expressed sequence tag and genomic data bases. |
| T9 | 939-1110 | Sentence | denotes | The cDNA contains an open reading frame encoding a protein of 388 amino acids with a predicted N-terminal transmembrane sequence typical of a type II membrane orientation. |
| T10 | 1111-1346 | Sentence | denotes | Likewise, the mouse homolog obtained from an expressed sequence tag and 5'-rapid amplification of cDNA ends of a mouse liver cDNA library encodes a type II transmembrane protein of 393 amino acids with 90.4% identity to human O-FucT-1. |
| T11 | 1347-1474 | Sentence | denotes | Homologs were also found in Drosophila and Caenorhabditis elegans with 41.2 and 29.4% identity to human O-FucT-1, respectively. |
| T12 | 1475-1574 | Sentence | denotes | The human gene (POFUT1) is on chromosome 20 between PLAGL2 and KIF3B, near the centromere at 20p11. |
| T13 | 1575-1661 | Sentence | denotes | The mouse gene (Pofut1) maps near Plagl2 on a homologous region of mouse chromosome 2. |
| T14 | 1662-1790 | Sentence | denotes | POFUT1 gene transcripts were expressed in all tissues examined, consistent with the widespread localization of the modification. |
| T15 | 1791-2006 | Sentence | denotes | Expression of a soluble form of human O-FucT-1 in insect cells yielded a protein of the predicted molecular weight with O-FucT-1 kinetic and enzymatic properties similar to those of O-FucT-1 purified from CHO cells. |
| T16 | 2007-2200 | Sentence | denotes | The identification of the gene encoding protein O-fucosyltransferase I now makes possible mutational strategies to examine the functions of the unusual O-fucose post-translational modification. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 58-66 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-fucose |
| T2 | 116-122 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | fucose |
| T3 | 157-165 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-fucose |
| T4 | 279-287 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-Fucose |
| T5 | 382-390 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-fucose |
| T6 | 533-541 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-fucose |
| T7 | 587-593 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | fucose |
| T8 | 2159-2167 | https://glytoucan.org/Structures/Glycans/G82576YO | denotes | O-fucose |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 869-874 | http://purl.obolibrary.org/obo/MAT_0000036 | denotes | heart |
| T2 | 1230-1235 | http://purl.obolibrary.org/obo/MAT_0000097 | denotes | liver |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 624-632 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T2 | 757-765 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T3 | 833-841 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T4 | 1086-1088 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
| PD-GlycoGenes20190927-B_T5 | 1264-1266 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
| PD-GlycoGenes20190927-B_T6 | 1337-1345 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T7 | 1451-1459 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T8 | 1491-1497 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| PD-GlycoGenes20190927-B_T9 | 1591-1597 | https://acgg.asia/db/ggdb/info/gg012 | denotes | Pofut1 |
| PD-GlycoGenes20190927-B_T10 | 1662-1668 | https://acgg.asia/db/ggdb/info/gg012 | denotes | POFUT1 |
| PD-GlycoGenes20190927-B_T11 | 1829-1837 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T12 | 1911-1919 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
| PD-GlycoGenes20190927-B_T13 | 1973-1981 | https://acgg.asia/db/ggdb/info/gg012 | denotes | O-FucT-1 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 664-679 | OrganismTaxon | denotes | Chinese hamster | 10029 |
| T2 | 751-756 | OrganismTaxon | denotes | human | 9606 |
| T3 | 863-868 | OrganismTaxon | denotes | human | 9606 |
| T4 | 1125-1130 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T6 | 1224-1229 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T8 | 1331-1336 | OrganismTaxon | denotes | human | 9606 |
| T9 | 1375-1385 | OrganismTaxon | denotes | Drosophila | 2081351|32281|7215 |
| T12 | 1390-1412 | OrganismTaxon | denotes | Caenorhabditis elegans | 6239 |
| T13 | 1445-1450 | OrganismTaxon | denotes | human | 9606 |
| T14 | 1479-1484 | OrganismTaxon | denotes | human | 9606 |
| T15 | 1579-1584 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T17 | 1642-1647 | OrganismTaxon | denotes | mouse | 10088|10090 |
| T19 | 1823-1828 | OrganismTaxon | denotes | human | 9606 |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 869-874 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/MAT_0000036 |
| T2 | 1230-1235 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/MAT_0000097 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 16-32 | Body_part | denotes | epidermal growth | http://purl.obolibrary.org/obo/UBERON_0000021 |
| T2 | 191-207 | Body_part | denotes | epidermal growth | http://purl.obolibrary.org/obo/UBERON_0000021 |
| T3 | 545-561 | Body_part | denotes | epidermal growth | http://purl.obolibrary.org/obo/UBERON_0000021 |
| T4 | 680-685 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T5 | 869-874 | Body_part | denotes | heart | http://purl.obolibrary.org/obo/UBERON_0000948|http://purl.obolibrary.org/obo/UBERON_0007100|http://purl.obolibrary.org/obo/UBERON_0015228|http://purl.obolibrary.org/obo/UBERON_0015230 |
| T9 | 1045-1058 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T10 | 1089-1097 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
| T13 | 1230-1235 | Body_part | denotes | liver | http://purl.obolibrary.org/obo/UBERON_0002107 |
| T14 | 1267-1280 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
| T15 | 1505-1515 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
| T16 | 1648-1658 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |