PubMed:11442633 JSONTXT

{"project":"PMID_GLOBAL","denotations":[{"id":"T1","span":{"begin":183,"end":191},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T4","span":{"begin":290,"end":312},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T5","span":{"begin":355,"end":377},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A1","pred":"mondo_id","subj":"T1","obj":"0003659"},{"id":"A2","pred":"mondo_id","subj":"T1","obj":"0003660"},{"id":"A3","pred":"mondo_id","subj":"T1","obj":"0005062"},{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0018908"},{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0018908"}],"text":"Identification and characterization of DAlk: a novel Drosophila melanogaster RTK which drives ERK activation in vivo.\nThe mammalian receptor protein tyrosine kinase (RTK), Anaplastic Lymphoma Kinase (ALK), was first described as the product of the t(2;5) chromosomal translocation found in non-Hodgkin's lymphoma. While the mechanism of ALK activation in non-Hodgkin's lymphoma has been examined, to date, no in vivo role for this orphan insulin receptor family RTK has been described."}