PubMed:1138817 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/1138817","sourcedb":"PubMed","sourceid":"1138817","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/1138817","text":"Blood coagulation profile in Indian patients with pre-eclampsia and eclampsia.\nTwelve Indian patients with pre-eclampsia, 15 with eclampsia and 15 with normal pregnancy in the third trimester were investigated. A systemic bleeding diathesis was encountered in two patients with eclampsia and in none with pre-eclampsia; two patients with pre-eclampsia, however, had excessive uterine haemorrhage. Coagulation studies showed statistically significant prolongation of thrombin time, elevation of serum fibrinogen degradation products (FDP) and hypofibrinogenaemia in patients with pre-eclampsia as well as eclampsia. In patients with eclampsia, significant thrombocytopenia also occurred. Euglobulin lysis time showed no significant change in patients with pre-eclampsia and eclampsia. There was no significant difference in the coagulation profile between patients with eclampsia and pre-eclampsia, except for more hypofibrinogenaemia in the former. The laboratory findings suggest the occurrence of intravascular coagulation in patients with pre-eclampsia and eclampsia.","tracks":[{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":494,"end":499},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":0,"end":5},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"attributes":[{"subj":"PD-UBERON-AE-B_T1","pred":"source","obj":"performance-test"},{"subj":"PD-UBERON-AE-B_T2","pred":"source","obj":"performance-test"}]},{"project":"sentences","denotations":[{"id":"TextSentencer_T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"TextSentencer_T2","span":{"begin":79,"end":210},"obj":"Sentence"},{"id":"TextSentencer_T3","span":{"begin":211,"end":396},"obj":"Sentence"},{"id":"TextSentencer_T4","span":{"begin":397,"end":614},"obj":"Sentence"},{"id":"TextSentencer_T5","span":{"begin":615,"end":686},"obj":"Sentence"},{"id":"TextSentencer_T6","span":{"begin":687,"end":783},"obj":"Sentence"},{"id":"TextSentencer_T7","span":{"begin":784,"end":948},"obj":"Sentence"},{"id":"TextSentencer_T8","span":{"begin":949,"end":1070},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":78},"obj":"Sentence"},{"id":"T2","span":{"begin":79,"end":210},"obj":"Sentence"},{"id":"T3","span":{"begin":211,"end":396},"obj":"Sentence"},{"id":"T4","span":{"begin":397,"end":614},"obj":"Sentence"},{"id":"T5","span":{"begin":615,"end":686},"obj":"Sentence"},{"id":"T6","span":{"begin":687,"end":783},"obj":"Sentence"},{"id":"T7","span":{"begin":784,"end":948},"obj":"Sentence"},{"id":"T8","span":{"begin":949,"end":1070},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"TextSentencer_T1","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T2","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T3","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T4","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T5","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T6","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T7","pred":"source","obj":"sentences"},{"subj":"TextSentencer_T8","pred":"source","obj":"sentences"},{"subj":"T1","pred":"source","obj":"sentences"},{"subj":"T2","pred":"source","obj":"sentences"},{"subj":"T3","pred":"source","obj":"sentences"},{"subj":"T4","pred":"source","obj":"sentences"},{"subj":"T5","pred":"source","obj":"sentences"},{"subj":"T6","pred":"source","obj":"sentences"},{"subj":"T7","pred":"source","obj":"sentences"},{"subj":"T8","pred":"source","obj":"sentences"}]},{"project":"UBERON-AE","denotations":[{"id":"PD-UBERON-AE-B_T1","span":{"begin":0,"end":5},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"PD-UBERON-AE-B_T2","span":{"begin":494,"end":499},"obj":"http://purl.obolibrary.org/obo/UBERON_0001977"}],"attributes":[{"subj":"PD-UBERON-AE-B_T1","pred":"source","obj":"UBERON-AE"},{"subj":"PD-UBERON-AE-B_T2","pred":"source","obj":"UBERON-AE"}]},{"project":"Preeclampsia","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":50,"end":63},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T2","span":{"begin":107,"end":120},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T3","span":{"begin":305,"end":318},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T4","span":{"begin":338,"end":351},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T5","span":{"begin":579,"end":592},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T6","span":{"begin":755,"end":768},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T7","span":{"begin":883,"end":896},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T8","span":{"begin":1042,"end":1055},"obj":"ORPHA:275555"}],"namespaces":[{"prefix":"ORPHA","uri":"www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=EN\u0026Expert="}],"attributes":[{"subj":"PD-Preeclampsia-B_T1","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T2","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T3","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T4","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T5","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T6","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T7","pred":"source","obj":"Preeclampsia"},{"subj":"PD-Preeclampsia-B_T8","pred":"source","obj":"Preeclampsia"}]},{"project":"Preeclampsia-compare","denotations":[{"id":"PD-Preeclampsia-B_T1","span":{"begin":50,"end":63},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T2","span":{"begin":107,"end":120},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T3","span":{"begin":305,"end":318},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T4","span":{"begin":338,"end":351},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T5","span":{"begin":579,"end":592},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T6","span":{"begin":755,"end":768},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T7","span":{"begin":883,"end":896},"obj":"ORPHA:275555"},{"id":"PD-Preeclampsia-B_T8","span":{"begin":1042,"end":1055},"obj":"ORPHA:27555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