PubMed:11323440
Annnotations
ggdb-test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 307-347 | https://acgg.asia/db/ggdb/info/gg041 | denotes | galactosyl ceramide 3-O-sulfotransferase |
| T2 | 363-371 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| T3 | 442-450 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T4 | 734-742 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T5 | 976-984 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T6 | 1122-1130 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T7 | 1139-1147 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T8 | 1278-1286 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T9 | 1350-1358 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T10 | 1363-1371 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T11 | 1407-1415 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T12 | 1454-1462 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T13 | 1479-1487 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| T14 | 1578-1586 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T15 | 1771-1779 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 108-127 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T2 | 171-180 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T4 | 307-326 | Glycan_Motif | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T5 | 477-496 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T6 | 522-527 | Glycan_Motif | denotes | core2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T7 | 659-664 | Glycan_Motif | denotes | core2 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00033MO |
| T8 | 786-795 | Glycan_Motif | denotes | galactose | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G68158BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T10 | 1048-1053 | Glycan_Motif | denotes | core1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00031MO |
| T11 | 1386-1405 | Glycan_Motif | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G65889KE |
| T12 | 1687-1706 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
| T13 | 1821-1840 | Glycan_Motif | denotes | N-acetyllactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00055MO |
GGDB-2020
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 307-347 | https://acgg.asia/db/ggdb/info/gg041 | denotes | galactosyl ceramide 3-O-sulfotransferase |
| T2 | 363-371 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| T3 | 442-450 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T4 | 734-742 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T5 | 976-984 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T6 | 1122-1130 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T7 | 1139-1147 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T8 | 1278-1286 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T9 | 1350-1358 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T10 | 1363-1371 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T11 | 1407-1415 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T12 | 1454-1462 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| T13 | 1479-1487 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| T14 | 1578-1586 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| T15 | 1771-1779 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-148 | Sentence | denotes | Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans. |
| T2 | 149-372 | Sentence | denotes | A novel cDNA-encoding galactose 3-O-sulfotransferase was cloned by screening the expressed sequence tag data base using the previously cloned cDNA encoding a galactosyl ceramide 3-O-sulfotransferase, which we term Gal3ST-1. |
| T3 | 373-547 | Sentence | denotes | The newly isolated cDNA encodes a novel 3-O-sulfotransferase, termed Gal3ST-3, that acts exclusively on N-acetyllactosamine present in N-glycans and core2-branched O-glycans. |
| T4 | 548-705 | Sentence | denotes | These conclusions were confirmed by analyzing CD43 chimeric proteins in Chinese hamster ovary cells expressing core2 beta1,6-N-acetylglucosaminyltransferase. |
| T5 | 706-934 | Sentence | denotes | The acceptor specificity of Gal3ST-3 contrasts with that of the recently cloned galactose 3-O-sulfotransferase (Honke, K., Tsuda, M., Koyota, S., Wada, Y., Iida-Tanaka, N., Ishizuka, I., Nakayama, J., and Taniguchi, N. (2001) J. |
| T6 | 935-940 | Sentence | denotes | Biol. |
| T7 | 941-946 | Sentence | denotes | Chem. |
| T8 | 947-1111 | Sentence | denotes | 276, 267-274), which we term Gal3ST-2 in the present study because the latter enzyme can also act on core1 O-glycan and type 1 oligosaccharides, Galbeta1-->3GlcNAc. |
| T9 | 1112-1335 | Sentence | denotes | Moreover, Gal3ST-3 but not Gal3ST-2 can act on Galbeta1-->4(sulfo-->6)GlcNAc, indicating that disulfated sulfo-->3Galbeta1-->4(sulfo-->6) GlcNAc-->R may be formed by Gal3ST-3 in combination with GlcNAc 6-O-sulfotransferase. |
| T10 | 1336-1520 | Sentence | denotes | Although both Gal3ST-2 and Gal3ST-3 do not act on galactosyl ceramide, Gal3ST-3 is only moderately more homologous to Gal3ST-2 (40.1%) than to Gal3ST-1 (38.0%) at the amino acid level. |
| T11 | 1521-1725 | Sentence | denotes | Northern blot analysis demonstrated that transcripts for Gal3ST-3 are predominantly expressed in the brain, kidney, and thyroid where the presence of 3'-sulfation of N-acetyllactosamine has been reported. |
| T12 | 1726-1866 | Sentence | denotes | These results indicate that the newly cloned Gal3ST-3 plays a critical role in 3'-sulfation of N-acetyllactosamine in both O- and N-glycans. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 108-127 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T2 | 171-180 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T3 | 171-180 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T4 | 307-326 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactosyl ceramide |
| T5 | 477-496 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T6 | 786-795 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactose |
| T7 | 786-795 | https://glytoucan.org/Structures/Glycans/G68158BT | denotes | galactose |
| T8 | 1048-1053 | https://glytoucan.org/Structures/Glycans/G00031MO | denotes | core1 |
| T9 | 1386-1405 | https://glytoucan.org/Structures/Glycans/G65889KE | denotes | galactosyl ceramide |
| T10 | 1687-1706 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
| T11 | 1821-1840 | https://glytoucan.org/Structures/Glycans/G00055MO | denotes | N-acetyllactosamine |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 307-326 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | galactosyl ceramide |
| T2 | 1386-1405 | http://www.glycoepitope.jp/epitopes/EP0074 | denotes | galactosyl ceramide |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 1622-1627 | http://purl.obolibrary.org/obo/MAT_0000098 | denotes | brain |
| T2 | 1629-1635 | http://purl.obolibrary.org/obo/MAT_0000119 | denotes | kidney |
| T3 | 1641-1648 | http://purl.obolibrary.org/obo/MAT_0000081 | denotes | thyroid |
glycogenes
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-GlycoGenes20190927-B_T1 | 307-347 | https://acgg.asia/db/ggdb/info/gg041 | denotes | galactosyl ceramide 3-O-sulfotransferase |
| PD-GlycoGenes20190927-B_T2 | 363-371 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| PD-GlycoGenes20190927-B_T3 | 442-450 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T4 | 734-742 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T5 | 976-984 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| PD-GlycoGenes20190927-B_T6 | 1122-1130 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T7 | 1139-1147 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| PD-GlycoGenes20190927-B_T8 | 1278-1286 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T9 | 1350-1358 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| PD-GlycoGenes20190927-B_T10 | 1363-1371 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T11 | 1407-1415 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T12 | 1454-1462 | https://acgg.asia/db/ggdb/info/gg042 | denotes | Gal3ST-2 |
| PD-GlycoGenes20190927-B_T13 | 1479-1487 | https://acgg.asia/db/ggdb/info/gg041 | denotes | Gal3ST-1 |
| PD-GlycoGenes20190927-B_T14 | 1578-1586 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
| PD-GlycoGenes20190927-B_T15 | 1707-1710 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
| PD-GlycoGenes20190927-B_T16 | 1771-1779 | https://acgg.asia/db/ggdb/info/gg043 | denotes | Gal3ST-3 |
NGLY1-deficiency
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| PD-NGLY1-deficiency-B_T1 | 1182-1188 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T2 | 1250-1256 | chem:24139 | denotes | GlcNAc |
| PD-NGLY1-deficiency-B_T3 | 1307-1313 | chem:24139 | denotes | GlcNAc |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 307-326 | Glycan | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T2 | 522-527 | Glycan | denotes | core2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T3 | 659-664 | Glycan | denotes | core2 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00033MO |
| T4 | 1048-1053 | Glycan | denotes | core1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G00031MO |
| T5 | 1386-1405 | Glycan | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1622-1627 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 1629-1635 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
| T3 | 1641-1648 | Body_part | denotes | thyroid | http://purl.obolibrary.org/obo/MAT_0000081 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 307-326 | Glycan | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
| T2 | 1386-1405 | Glycan | denotes | galactosyl ceramide | https://api.glycosmos.org/wurcs2image/latest/png/binary/G65889KE |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 307-326 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosyl ceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
| T2 | 1386-1405 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosyl ceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 636-641 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T2 | 1622-1627 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955 |
| T3 | 1629-1635 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T4 | 1641-1648 | Body_part | denotes | thyroid | http://purl.obolibrary.org/obo/UBERON_0002046 |
GlyCosmos15-Taxon
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 44-49 | Organism | denotes | human | 9606 |
| T2 | 620-635 | Organism | denotes | Chinese hamster | 10029 |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-148 | Sentence | denotes | Molecular cloning and expression of a novel human beta-Gal-3-O-sulfotransferase that acts preferentially on N-acetyllactosamine in N- and O-glycans. |
| T2 | 149-372 | Sentence | denotes | A novel cDNA-encoding galactose 3-O-sulfotransferase was cloned by screening the expressed sequence tag data base using the previously cloned cDNA encoding a galactosyl ceramide 3-O-sulfotransferase, which we term Gal3ST-1. |
| T3 | 373-547 | Sentence | denotes | The newly isolated cDNA encodes a novel 3-O-sulfotransferase, termed Gal3ST-3, that acts exclusively on N-acetyllactosamine present in N-glycans and core2-branched O-glycans. |
| T4 | 548-705 | Sentence | denotes | These conclusions were confirmed by analyzing CD43 chimeric proteins in Chinese hamster ovary cells expressing core2 beta1,6-N-acetylglucosaminyltransferase. |
| T5 | 706-1111 | Sentence | denotes | The acceptor specificity of Gal3ST-3 contrasts with that of the recently cloned galactose 3-O-sulfotransferase (Honke, K., Tsuda, M., Koyota, S., Wada, Y., Iida-Tanaka, N., Ishizuka, I., Nakayama, J., and Taniguchi, N. (2001) J. Biol. Chem. 276, 267-274), which we term Gal3ST-2 in the present study because the latter enzyme can also act on core1 O-glycan and type 1 oligosaccharides, Galbeta1-->3GlcNAc. |
| T6 | 1112-1335 | Sentence | denotes | Moreover, Gal3ST-3 but not Gal3ST-2 can act on Galbeta1-->4(sulfo-->6)GlcNAc, indicating that disulfated sulfo-->3Galbeta1-->4(sulfo-->6) GlcNAc-->R may be formed by Gal3ST-3 in combination with GlcNAc 6-O-sulfotransferase. |
| T7 | 1336-1520 | Sentence | denotes | Although both Gal3ST-2 and Gal3ST-3 do not act on galactosyl ceramide, Gal3ST-3 is only moderately more homologous to Gal3ST-2 (40.1%) than to Gal3ST-1 (38.0%) at the amino acid level. |
| T8 | 1521-1725 | Sentence | denotes | Northern blot analysis demonstrated that transcripts for Gal3ST-3 are predominantly expressed in the brain, kidney, and thyroid where the presence of 3'-sulfation of N-acetyllactosamine has been reported. |
| T9 | 1726-1866 | Sentence | denotes | These results indicate that the newly cloned Gal3ST-3 plays a critical role in 3'-sulfation of N-acetyllactosamine in both O- and N-glycans. |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 307-326 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosyl ceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
| T2 | 1386-1405 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | galactosyl ceramide | http://www.glycoepitope.jp/epitopes/EP0074 |
GlyCosmos15-FMA
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 636-641 | Body_part | denotes | ovary | FMA:7209 |
| T2 | 1622-1627 | Body_part | denotes | brain | FMA:50801 |
| T3 | 1629-1635 | Body_part | denotes | kidney | FMA:7203 |
GlyCosmos15-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 1622-1627 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/MAT_0000098 |
| T2 | 1629-1635 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/MAT_0000119 |
| T3 | 1641-1648 | Body_part | denotes | thyroid | http://purl.obolibrary.org/obo/MAT_0000081 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 44-49 | OrganismTaxon | denotes | human | 9606 |
| T2 | 620-635 | OrganismTaxon | denotes | Chinese hamster | 10029 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 636-641 | Body_part | denotes | ovary | http://purl.obolibrary.org/obo/UBERON_0000992 |
| T2 | 1622-1627 | Body_part | denotes | brain | http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636 |
| T4 | 1629-1635 | Body_part | denotes | kidney | http://purl.obolibrary.org/obo/UBERON_0002113 |
| T5 | 1641-1648 | Body_part | denotes | thyroid | http://purl.obolibrary.org/obo/UBERON_0002046 |
GlyCosmos15-Lectin
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-60 | GL_000491 | denotes | Gal-3 |
Lectin_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 55-60 | GL_000491 | denotes | Gal-3 |