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PubMed:11297552 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-108 Sentence denotes Platelet-derived growth factor C (PDGF-C), a novel growth factor that binds to PDGF alpha and beta receptor.
T2 109-223 Sentence denotes We have characterized platelet-derived growth factor (PDGF) C, a novel growth factor belonging to the PDGF family.
T3 224-491 Sentence denotes PDGF-C is a multidomain protein with the N-terminal region homologous to the extracellular CUB domain of neuropilin-1, and the C-terminal region consists of a growth factor domain (GFD) with homology to vascular endothelial growth factor (25%) and PDGF A-chain (23%).
T4 492-594 Sentence denotes A serum-sensitive cleavage site between the two domains allows release of the GFD from the CUB domain.
T5 595-835 Sentence denotes Competition binding and immunoprecipitation studies on cells bearing both PDGF alpha and beta receptors reveal a high affinity binding of recombinant GFD (PDGF-CC) to PDGF receptor-alpha homodimers and PDGF receptor-alpha/beta heterodimers.
T6 836-996 Sentence denotes PDGF-CC exhibits greater mitogenic potency than PDGF-AA and comparable or greater mitogenic activity than PDGF-AB and PDGF-BB on several mesenchymal cell types.
T7 997-1160 Sentence denotes Analysis of PDGF-CC in vivo in a diabetic mouse model of delayed wound healing showed that PDGF-CC significantly enhanced repair of a full-thickness skin excision.
T8 1161-1363 Sentence denotes Together, these studies describe a third member of the PDGF family (PDGF-C) as a potent mitogen for cells of mesenchymal origin in in vitro and in vivo systems with a binding pattern similar to PDGF-AB.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1146-1150 http://purl.obolibrary.org/obo/MAT_0000284 denotes skin

FSU-PRGE

Id Subject Object Predicate Lexical cue
T1 0-32 protein denotes Platelet-derived growth factor C
T2 34-40 protein denotes PDGF-C
T3 51-64 protein denotes growth factor
T4 79-107 protein denotes PDGF alpha and beta receptor
T5 131-170 protein denotes platelet-derived growth factor (PDGF) C
T6 180-193 protein denotes growth factor
T7 211-222 protein denotes PDGF family
T8 224-230 protein denotes PDGF-C
T9 329-341 protein denotes neuropilin-1
T10 383-396 protein denotes growth factor
T11 427-461 protein denotes vascular endothelial growth factor
T12 472-478 protein denotes PDGF A
T13 669-698 protein denotes PDGF alpha and beta receptors
T14 750-757 protein denotes PDGF-CC
T15 762-781 protein denotes PDGF receptor-alpha
T16 797-821 protein denotes PDGF receptor-alpha/beta
T17 836-843 protein denotes PDGF-CC
T18 884-891 protein denotes PDGF-AA
T19 942-949 protein denotes PDGF-AB
T20 954-961 protein denotes PDGF-BB
T21 1009-1016 protein denotes PDGF-CC
T22 1088-1095 protein denotes PDGF-CC
T23 1216-1227 protein denotes PDGF family
T24 1229-1235 protein denotes PDGF-C
T25 1355-1362 protein denotes PDGF-AB

AIMed

Id Subject Object Predicate Lexical cue
T1 0-32 protein denotes Platelet-derived growth factor C
T2 34-40 protein denotes PDGF-C
T3 79-89 protein denotes PDGF alpha
T4 131-170 protein denotes platelet-derived growth factor (PDGF) C
T5 224-230 protein denotes PDGF-C
T6 329-341 protein denotes neuropilin-1
T7 436-461 protein denotes endothelial growth factor
T8 472-478 protein denotes PDGF A
T9 669-679 protein denotes PDGF alpha
T10 750-757 protein denotes PDGF-CC
T11 762-781 protein denotes PDGF receptor-alpha
T12 797-816 protein denotes PDGF receptor-alpha
T13 836-843 protein denotes PDGF-CC
T14 884-891 protein denotes PDGF-AA
T15 942-949 protein denotes PDGF-AB
T16 954-961 protein denotes PDGF-BB
T17 1009-1016 protein denotes PDGF-CC
T18 1088-1095 protein denotes PDGF-CC
T19 1229-1235 protein denotes PDGF-C
T20 1355-1362 protein denotes PDGF-AB

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 405-408 Disease denotes GFD http://purl.obolibrary.org/obo/MONDO_0007612
T2 570-573 Disease denotes GFD http://purl.obolibrary.org/obo/MONDO_0007612
T3 745-748 Disease denotes GFD http://purl.obolibrary.org/obo/MONDO_0007612
T4 1062-1067 Disease denotes wound http://purl.obolibrary.org/obo/MONDO_0021178

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 1039-1044 OrganismTaxon denotes mouse 10088|10090

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1146-1150 Body_part denotes skin http://purl.obolibrary.org/obo/MAT_0000284

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 0-8 Body_part denotes Platelet http://purl.obolibrary.org/obo/CL_0000233
T2 131-139 Body_part denotes platelet http://purl.obolibrary.org/obo/CL_0000233
T3 301-314 Body_part denotes extracellular http://purl.obolibrary.org/obo/GO_0005576
T4 973-989 Body_part denotes mesenchymal cell http://purl.obolibrary.org/obo/CL_0008019
T5 1146-1150 Body_part denotes skin http://purl.obolibrary.org/obo/UBERON_0000014|http://purl.obolibrary.org/obo/UBERON_0001003|http://purl.obolibrary.org/obo/UBERON_0002097|http://purl.obolibrary.org/obo/UBERON_0002199

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 0-8 Cell denotes Platelet http://purl.obolibrary.org/obo/CL:0000233
T2 131-139 Cell denotes platelet http://purl.obolibrary.org/obo/CL:0000233
T3 973-989 Cell denotes mesenchymal cell http://purl.obolibrary.org/obo/CL:0008019