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Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-92 Sentence denotes Association of nitric oxide production and apoptosis in a model of experimental nephropathy.
T2 93-104 Sentence denotes BACKGROUND:
T3 105-246 Sentence denotes In recent studies increased amounts of nitric oxide (NO) and apoptosis have been implicated in various pathological conditions in the kidney.
T4 247-410 Sentence denotes We have studied the role of NO and its association with apoptosis in an experimental model of nephrotic syndrome induced by a single injection of adriamycin (ADR).
T5 411-419 Sentence denotes METHODS:
T6 420-612 Sentence denotes The alteration in the NO pathway was assessed by measuring nitrite levels in serum/urine and by evaluating the changes in vascular reactivity of the isolated perfused rat kidney (IPRK) system.
T7 613-689 Sentence denotes Rats were stratified into control groups and ADR-induced nephropathy groups.
T8 690-872 Sentence denotes These two groups were then divided into: group 1, animals receiving saline; and group 2, animals receiving aminoguanidine (AG) which is a specific inhibitor of inducible-NO synthase.
T9 873-955 Sentence denotes On day 21, rats were sacrificed after obtaining material for biochemical analysis.
T10 956-964 Sentence denotes RESULTS:
T11 965-1124 Sentence denotes Histopathological examination of the kidneys of rats treated with ADR revealed focal areas of mesangial proliferation and mild tubulointerstitial inflammation.
T12 1125-1236 Sentence denotes They also had significantly higher levels of proteinuria compared with control and treatment groups (P < 0.05).
T13 1237-1327 Sentence denotes Urine nitrite levels were significantly increased in the ADR-nephropathy group (P < 0.05).
T14 1328-1447 Sentence denotes In the IPRK phenylephrine and acetylcholine related responses were significantly impaired in the ADR-nephropathy group.
T15 1448-1487 Sentence denotes Apoptosis was not detected in controls.
T16 1488-1600 Sentence denotes However, in the ADR-nephropathy group, numerous apoptotic cells were identified in the tubulointerstitial areas.
T17 1601-1717 Sentence denotes Double staining revealed numerous interstitial apoptotic cells to stain for ED1, a marker for monocytes/macrophages.
T18 1718-1863 Sentence denotes Treatment with AG prevented the impairment of renal vascular bed responses and reduced both urine nitrite levels and apoptosis to control levels.
T19 1864-1875 Sentence denotes CONCLUSION:
T20 1876-1993 Sentence denotes We suggest that interactions between NO and apoptosis are important in the pathogenesis of the ADR-induced nephrosis.
T1 0-92 Sentence denotes Association of nitric oxide production and apoptosis in a model of experimental nephropathy.
T2 93-104 Sentence denotes BACKGROUND:
T3 105-246 Sentence denotes In recent studies increased amounts of nitric oxide (NO) and apoptosis have been implicated in various pathological conditions in the kidney.
T4 247-410 Sentence denotes We have studied the role of NO and its association with apoptosis in an experimental model of nephrotic syndrome induced by a single injection of adriamycin (ADR).
T5 411-419 Sentence denotes METHODS:
T6 420-612 Sentence denotes The alteration in the NO pathway was assessed by measuring nitrite levels in serum/urine and by evaluating the changes in vascular reactivity of the isolated perfused rat kidney (IPRK) system.
T7 613-689 Sentence denotes Rats were stratified into control groups and ADR-induced nephropathy groups.
T8 690-872 Sentence denotes These two groups were then divided into: group 1, animals receiving saline; and group 2, animals receiving aminoguanidine (AG) which is a specific inhibitor of inducible-NO synthase.
T9 873-955 Sentence denotes On day 21, rats were sacrificed after obtaining material for biochemical analysis.
T10 956-964 Sentence denotes RESULTS:
T11 965-1124 Sentence denotes Histopathological examination of the kidneys of rats treated with ADR revealed focal areas of mesangial proliferation and mild tubulointerstitial inflammation.
T12 1125-1236 Sentence denotes They also had significantly higher levels of proteinuria compared with control and treatment groups (P < 0.05).
T13 1237-1327 Sentence denotes Urine nitrite levels were significantly increased in the ADR-nephropathy group (P < 0.05).
T14 1328-1447 Sentence denotes In the IPRK phenylephrine and acetylcholine related responses were significantly impaired in the ADR-nephropathy group.
T15 1448-1487 Sentence denotes Apoptosis was not detected in controls.
T16 1488-1600 Sentence denotes However, in the ADR-nephropathy group, numerous apoptotic cells were identified in the tubulointerstitial areas.
T17 1601-1717 Sentence denotes Double staining revealed numerous interstitial apoptotic cells to stain for ED1, a marker for monocytes/macrophages.
T18 1718-1863 Sentence denotes Treatment with AG prevented the impairment of renal vascular bed responses and reduced both urine nitrite levels and apoptosis to control levels.
T19 1864-1875 Sentence denotes CONCLUSION:
T20 1876-1993 Sentence denotes We suggest that interactions between NO and apoptosis are important in the pathogenesis of the ADR-induced nephrosis.

bc5cdr-valid-experiment

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-661 Chemical denotes ADR
T12 670-681 Disease denotes nephropathy
T13 797-811 Chemical denotes aminoguanidine
T14 813-815 Chemical denotes AG
T15 860-862 Chemical denotes NO
T16 1031-1034 Chemical denotes ADR
T17 1059-1082 Disease denotes mesangial proliferation
T18 1092-1123 Disease denotes tubulointerstitial inflammation
T19 1170-1181 Disease denotes proteinuria
T20 1243-1250 Chemical denotes nitrite
T21 1294-1297 Chemical denotes ADR
T22 1298-1309 Disease denotes nephropathy
T23 1340-1353 Chemical denotes phenylephrine
T24 1358-1371 Chemical denotes acetylcholine
T25 1425-1428 Chemical denotes ADR
T26 1429-1440 Disease denotes nephropathy
T27 1504-1507 Chemical denotes ADR
T28 1508-1519 Disease denotes nephropathy
T29 1733-1735 Chemical denotes AG
T30 1816-1823 Chemical denotes nitrite
T31 1913-1915 Chemical denotes NO
T32 1971-1974 Chemical denotes ADR
T33 1983-1992 Disease denotes nephrosis

bc5cdr-valid-deepseek-nr-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 158-160 Chemical denotes NO
T3 341-359 Disease denotes nephrotic syndrome
T4 393-403 Chemical denotes adriamycin
T5 405-408 Chemical denotes ADR
T6 670-688 Disease denotes nephropathy groups
T7 797-811 Chemical denotes aminoguanidine
T8 813-815 Chemical denotes AG
T9 1294-1315 Disease denotes ADR-nephropathy group
T10 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-661 Chemical denotes ADR
T12 670-681 Disease denotes nephropathy
T13 797-811 Chemical denotes aminoguanidine
T14 813-815 Chemical denotes AG
T15 860-862 Chemical denotes NO
T16 1031-1034 Chemical denotes ADR
T17 1059-1082 Disease denotes mesangial proliferation
T18 1092-1123 Disease denotes tubulointerstitial inflammation
T19 1170-1181 Disease denotes proteinuria
T20 1243-1250 Chemical denotes nitrite
T21 1294-1297 Chemical denotes ADR
T22 1298-1309 Disease denotes nephropathy
T23 1340-1353 Chemical denotes phenylephrine
T24 1358-1371 Chemical denotes acetylcholine
T25 1425-1428 Chemical denotes ADR
T26 1429-1440 Disease denotes nephropathy
T27 1504-1507 Chemical denotes ADR
T28 1508-1519 Disease denotes nephropathy
T29 1733-1735 Chemical denotes AG
T30 1816-1823 Chemical denotes nitrite
T31 1913-1915 Chemical denotes NO
T32 1971-1974 Chemical denotes ADR
T33 1983-1992 Disease denotes nephrosis

bc5cdr-valid-gemini-r-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-681 Disease denotes ADR-induced nephropathy
T12 797-811 Chemical denotes aminoguanidine
T13 813-815 Chemical denotes AG
T14 860-862 Chemical denotes NO
T15 1031-1034 Chemical denotes ADR
T16 1059-1082 Disease denotes mesangial proliferation
T17 1092-1123 Disease denotes tubulointerstitial inflammation
T18 1170-1181 Disease denotes proteinuria
T19 1243-1250 Chemical denotes nitrite
T20 1294-1309 Disease denotes ADR-nephropathy
T21 1340-1353 Chemical denotes phenylephrine
T22 1358-1371 Chemical denotes acetylcholine
T23 1733-1735 Chemical denotes AG
T24 1816-1823 Chemical denotes nitrite
T25 1913-1915 Chemical denotes NO
T26 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gemini-nr-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-681 Disease denotes ADR-induced nephropathy
T12 758-764 Chemical denotes saline
T13 797-811 Chemical denotes aminoguanidine
T14 813-815 Chemical denotes AG
T15 1059-1082 Disease denotes mesangial proliferation
T16 1087-1123 Disease denotes mild tubulointerstitial inflammation
T17 1170-1181 Disease denotes proteinuria
T18 1243-1250 Chemical denotes nitrite
T19 1294-1309 Disease denotes ADR-nephropathy
T20 1340-1353 Chemical denotes phenylephrine
T21 1358-1371 Chemical denotes acetylcholine
T22 1733-1735 Chemical denotes AG
T23 1816-1823 Chemical denotes nitrite
T24 1913-1915 Chemical denotes NO
T25 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gemini-nr-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 67-91 Disease denotes experimental nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 166-175 Disease denotes apoptosis
T6 275-277 Chemical denotes NO
T7 303-312 Disease denotes apoptosis
T8 341-359 Disease denotes nephrotic syndrome
T9 393-403 Chemical denotes adriamycin
T10 405-408 Chemical denotes ADR
T11 442-444 Chemical denotes NO
T12 479-486 Chemical denotes nitrite
T13 658-681 Disease denotes ADR-induced nephropathy
T14 758-764 Chemical denotes saline
T15 797-811 Chemical denotes aminoguanidine
T16 813-815 Chemical denotes AG
T17 850-871 Chemical denotes inducible-NO synthase
T18 1059-1082 Disease denotes mesangial proliferation
T19 1092-1123 Disease denotes tubulointerstitial inflammation
T20 1170-1181 Disease denotes proteinuria
T21 1243-1250 Chemical denotes nitrite
T22 1294-1309 Disease denotes ADR-nephropathy
T23 1340-1353 Chemical denotes phenylephrine
T24 1358-1371 Chemical denotes acetylcholine
T25 1448-1457 Disease denotes Apoptosis
T26 1733-1735 Chemical denotes AG
T27 1835-1844 Disease denotes apoptosis
T28 1913-1915 Chemical denotes NO
T29 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gemini-r-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 43-52 Disease denotes apoptosis
T3 80-91 Disease denotes nephropathy
T4 144-156 Chemical denotes nitric oxide
T5 158-160 Chemical denotes NO
T6 166-175 Disease denotes apoptosis
T7 275-277 Chemical denotes NO
T8 303-312 Disease denotes apoptosis
T9 341-359 Disease denotes nephrotic syndrome
T10 393-403 Chemical denotes adriamycin
T11 405-408 Chemical denotes ADR
T12 442-444 Chemical denotes NO
T13 479-486 Chemical denotes nitrite
T14 658-681 Disease denotes ADR-induced nephropathy
T15 758-764 Chemical denotes saline
T16 797-811 Chemical denotes aminoguanidine
T17 813-815 Chemical denotes AG
T18 860-862 Chemical denotes NO
T19 1059-1082 Disease denotes mesangial proliferation
T20 1092-1123 Disease denotes tubulointerstitial inflammation
T21 1170-1181 Disease denotes proteinuria
T22 1243-1250 Chemical denotes nitrite
T23 1294-1309 Disease denotes ADR-nephropathy
T24 1340-1353 Chemical denotes phenylephrine
T25 1358-1371 Chemical denotes acetylcholine
T26 1448-1457 Disease denotes Apoptosis
T27 1677-1680 Chemical denotes ED1
T28 1733-1735 Chemical denotes AG
T29 1835-1844 Disease denotes apoptosis
T30 1913-1915 Chemical denotes NO
T31 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gpt-nr-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 479-486 Chemical denotes nitrite
T10 658-681 Disease denotes ADR-induced nephropathy
T11 797-811 Chemical denotes aminoguanidine
T12 813-815 Chemical denotes AG
T13 1031-1034 Chemical denotes ADR
T14 1170-1181 Disease denotes proteinuria
T15 1243-1250 Chemical denotes nitrite
T16 1294-1309 Disease denotes ADR-nephropathy
T17 1340-1353 Chemical denotes phenylephrine
T18 1358-1371 Chemical denotes acetylcholine
T19 1425-1440 Disease denotes ADR-nephropathy
T20 1504-1519 Disease denotes ADR-nephropathy
T21 1733-1735 Chemical denotes AG
T22 1816-1823 Chemical denotes nitrite
T23 1913-1915 Chemical denotes NO
T24 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gpt-r-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-661 Chemical denotes ADR
T12 758-764 Chemical denotes saline
T13 797-811 Chemical denotes aminoguanidine
T14 813-815 Chemical denotes AG
T15 860-862 Chemical denotes NO
T16 1031-1034 Chemical denotes ADR
T17 1092-1123 Disease denotes tubulointerstitial inflammation
T18 1170-1181 Disease denotes proteinuria
T19 1243-1250 Chemical denotes nitrite
T20 1294-1297 Chemical denotes ADR
T21 1340-1353 Chemical denotes phenylephrine
T22 1358-1371 Chemical denotes acetylcholine
T23 1425-1428 Chemical denotes ADR
T24 1504-1507 Chemical denotes ADR
T25 1733-1735 Chemical denotes AG
T26 1816-1823 Chemical denotes nitrite
T27 1913-1915 Chemical denotes NO
T28 1971-1974 Chemical denotes ADR

bc5cdr-valid-gpt-r-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-681 Disease denotes ADR-induced nephropathy
T12 797-811 Chemical denotes aminoguanidine
T13 813-815 Chemical denotes AG
T14 1031-1034 Chemical denotes ADR
T15 1092-1123 Disease denotes tubulointerstitial inflammation
T16 1170-1181 Disease denotes proteinuria
T17 1243-1250 Chemical denotes nitrite
T18 1294-1309 Disease denotes ADR-nephropathy
T19 1340-1353 Chemical denotes phenylephrine
T20 1358-1371 Chemical denotes acetylcholine
T21 1425-1440 Disease denotes ADR-nephropathy
T22 1504-1519 Disease denotes ADR-nephropathy
T23 1733-1735 Chemical denotes AG
T24 1816-1823 Chemical denotes nitrite
T25 1913-1915 Chemical denotes NO
T26 1971-1992 Disease denotes ADR-induced nephrosis

bc5cdr-valid-gpt-nr-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 341-359 Disease denotes nephrotic syndrome
T5 393-403 Chemical denotes adriamycin
T6 442-444 Chemical denotes NO
T7 479-486 Chemical denotes nitrite
T8 591-597 Disease denotes kidney
T9 658-669 Chemical denotes ADR-induced
T10 670-681 Disease denotes nephropathy
T11 758-764 Chemical denotes saline
T12 797-811 Chemical denotes aminoguanidine
T13 850-862 Chemical denotes inducible-NO
T14 998-1009 Disease denotes the kidneys
T15 1031-1034 Chemical denotes ADR
T16 1092-1123 Disease denotes tubulointerstitial inflammation
T17 1170-1181 Disease denotes proteinuria
T18 1243-1250 Chemical denotes nitrite
T19 1294-1309 Disease denotes ADR-nephropathy
T20 1340-1353 Chemical denotes phenylephrine
T21 1358-1371 Chemical denotes acetylcholine
T22 1425-1440 Disease denotes ADR-nephropathy
T23 1504-1519 Disease denotes ADR-nephropathy
T24 1733-1735 Chemical denotes AG
T25 1816-1823 Chemical denotes nitrite
T26 1913-1915 Chemical denotes NO
T27 1983-1992 Disease denotes nephrosis

bc5cdr-valid-deepseek-r-ng

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-661 Chemical denotes ADR
T12 670-681 Disease denotes nephropathy
T13 758-764 Chemical denotes saline
T14 797-811 Chemical denotes aminoguanidine
T15 813-815 Chemical denotes AG
T16 860-862 Chemical denotes NO
T17 1031-1034 Chemical denotes ADR
T18 1170-1181 Disease denotes proteinuria
T19 1243-1250 Chemical denotes nitrite
T20 1294-1297 Chemical denotes ADR
T21 1298-1309 Disease denotes nephropathy
T22 1340-1353 Chemical denotes phenylephrine
T23 1358-1371 Chemical denotes acetylcholine
T24 1983-1992 Disease denotes nephrosis

bc5cdr-valid-gemini-r-m

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 670-681 Disease denotes nephropathy
T12 797-811 Chemical denotes aminoguanidine
T13 813-815 Chemical denotes AG
T14 1031-1034 Chemical denotes ADR
T15 1092-1123 Disease denotes tubulointerstitial inflammation
T16 1170-1181 Disease denotes proteinuria
T17 1243-1250 Chemical denotes nitrite
T18 1298-1309 Disease denotes nephropathy
T19 1340-1353 Chemical denotes phenylephrine
T20 1358-1371 Chemical denotes acetylcholine
T21 1733-1735 Chemical denotes AG
T22 1816-1823 Chemical denotes nitrite
T23 1913-1915 Chemical denotes NO
T24 1983-1992 Disease denotes nephrosis

bc5cdr-valid-gpt-r-m2

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 670-681 Disease denotes nephropathy
T12 797-811 Chemical denotes aminoguanidine
T13 813-815 Chemical denotes AG
T14 1031-1034 Chemical denotes ADR
T15 1092-1123 Disease denotes tubulointerstitial inflammation
T16 1170-1181 Disease denotes proteinuria
T17 1243-1250 Chemical denotes nitrite
T18 1294-1297 Chemical denotes ADR
T19 1298-1309 Disease denotes nephropathy
T20 1340-1353 Chemical denotes phenylephrine
T21 1358-1371 Chemical denotes acetylcholine
T22 1425-1428 Chemical denotes ADR
T23 1429-1440 Disease denotes nephropathy
T24 1504-1507 Chemical denotes ADR
T25 1508-1519 Disease denotes nephropathy
T26 1733-1735 Chemical denotes AG
T27 1816-1823 Chemical denotes nitrite
T28 1913-1915 Chemical denotes NO
T29 1971-1974 Chemical denotes ADR
T30 1983-1992 Disease denotes nephrosis

bc5cdr-valid-deepseek-r-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 479-486 Chemical denotes nitrite
T10 658-661 Chemical denotes ADR
T11 670-681 Disease denotes nephropathy
T12 797-811 Chemical denotes aminoguanidine
T13 813-815 Chemical denotes AG
T14 860-862 Chemical denotes NO
T15 1111-1123 Disease denotes inflammation
T16 1170-1181 Disease denotes proteinuria
T17 1340-1353 Chemical denotes phenylephrine
T18 1358-1371 Chemical denotes acetylcholine
T19 1983-1992 Disease denotes nephrosis

bc5cdr-valid-deepseek-nr-g

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 158-160 Chemical denotes NO
T3 166-175 Disease denotes apoptosis
T4 275-277 Chemical denotes NO
T5 303-312 Disease denotes apoptosis
T6 393-403 Chemical denotes adriamycin
T7 405-408 Chemical denotes ADR
T8 658-661 Chemical denotes ADR
T9 813-815 Chemical denotes AG
T10 860-862 Chemical denotes NO

bc5cdr-valid-deepseek-r-m

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 158-160 Chemical denotes NO
T4 341-359 Disease denotes nephrotic syndrome
T5 393-403 Chemical denotes adriamycin
T6 405-408 Chemical denotes ADR
T7 442-444 Chemical denotes NO
T8 479-486 Chemical denotes nitrite
T9 658-661 Chemical denotes ADR
T10 670-681 Disease denotes nephropathy
T11 797-811 Chemical denotes aminoguanidine
T12 813-815 Chemical denotes AG
T13 860-862 Chemical denotes NO
T14 1031-1034 Chemical denotes ADR
T15 1111-1123 Disease denotes inflammation
T16 1170-1181 Disease denotes proteinuria
T17 1243-1250 Chemical denotes nitrite
T18 1340-1353 Chemical denotes phenylephrine
T19 1358-1371 Chemical denotes acetylcholine
T20 1983-1992 Disease denotes nephrosis

bc5cdr-valid-gpt-r-m

Id Subject Object Predicate Lexical cue
T1 15-27 Chemical denotes nitric oxide
T2 80-91 Disease denotes nephropathy
T3 144-156 Chemical denotes nitric oxide
T4 158-160 Chemical denotes NO
T5 275-277 Chemical denotes NO
T6 341-359 Disease denotes nephrotic syndrome
T7 393-403 Chemical denotes adriamycin
T8 405-408 Chemical denotes ADR
T9 442-444 Chemical denotes NO
T10 479-486 Chemical denotes nitrite
T11 658-661 Chemical denotes ADR
T12 670-681 Disease denotes nephropathy
T13 797-811 Chemical denotes aminoguanidine
T14 813-815 Chemical denotes AG
T15 1031-1034 Chemical denotes ADR
T16 1092-1123 Disease denotes tubulointerstitial inflammation
T17 1170-1181 Disease denotes proteinuria
T18 1243-1250 Chemical denotes nitrite
T19 1294-1297 Chemical denotes ADR
T20 1298-1309 Disease denotes nephropathy
T21 1340-1353 Chemical denotes phenylephrine
T22 1358-1371 Chemical denotes acetylcholine
T23 1425-1428 Chemical denotes ADR
T24 1429-1440 Disease denotes nephropathy
T25 1504-1507 Chemical denotes ADR
T26 1508-1519 Disease denotes nephropathy
T27 1733-1735 Chemical denotes AG
T28 1816-1823 Chemical denotes nitrite
T29 1913-1915 Chemical denotes NO
T30 1971-1974 Chemical denotes ADR
T31 1983-1992 Disease denotes nephrosis