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PubMed:11030745 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-103 Sentence denotes Stereochemical metrics of lectin-carbohydrate interactions: comparison with protein-protein interfaces.
TextSentencer_T2 104-362 Sentence denotes A global census of stereochemical metrics including interface size, hydropathy, amino acid propensities, packing and hydrogen bonding was carried out on 32 x-ray-elucidated structures of lectin-carbohydrate complexes covering eight different lectin families.
TextSentencer_T3 363-467 Sentence denotes It is shown that the interactions at primary binding subsites are more efficient than at other subsites.
TextSentencer_T4 468-611 Sentence denotes Another salient behavior found for primary subsites was a marked negative correlation between the interface size and the polar surface content.
TextSentencer_T5 612-816 Sentence denotes It is noteworthy that this demographic rule is delineated by lectins with unrelated phylogenetic origin, indicating that independent interface architectures have evolved through common optimization paths.
TextSentencer_T6 817-948 Sentence denotes The structural properties of lectin-carbohydrate interfaces were compared with those characterizing a set of 32 protein homodimers.
TextSentencer_T7 949-1096 Sentence denotes Overall, the analysis shows that the stereochemical bases of lectin-carbohydrate and protein-protein interfaces differ drastically from each other.
TextSentencer_T8 1097-1286 Sentence denotes In comparison with protein-protein complexes, lectin-carbohydrate interfaces have superior packing efficiency, better hydrogen bonding stereochemistry, and higher interaction cooperativity.
TextSentencer_T9 1287-1369 Sentence denotes A similar conclusion holds in the comparison with protein-protein heterocomplexes.
TextSentencer_T10 1370-1619 Sentence denotes We propose that the energetic consequence of this better interaction geometry is a larger decrease in free energy per unit of area buried, feature that enables lectins and carbohydrates to form stable complexes with relatively small interface areas.
TextSentencer_T11 1620-1784 Sentence denotes These observations lend support to the emerging notion that systems differing from each other in their stereochemical metrics may rely on different energetic bases.
T1 0-103 Sentence denotes Stereochemical metrics of lectin-carbohydrate interactions: comparison with protein-protein interfaces.
T2 104-362 Sentence denotes A global census of stereochemical metrics including interface size, hydropathy, amino acid propensities, packing and hydrogen bonding was carried out on 32 x-ray-elucidated structures of lectin-carbohydrate complexes covering eight different lectin families.
T3 363-467 Sentence denotes It is shown that the interactions at primary binding subsites are more efficient than at other subsites.
T4 468-611 Sentence denotes Another salient behavior found for primary subsites was a marked negative correlation between the interface size and the polar surface content.
T5 612-816 Sentence denotes It is noteworthy that this demographic rule is delineated by lectins with unrelated phylogenetic origin, indicating that independent interface architectures have evolved through common optimization paths.
T6 817-948 Sentence denotes The structural properties of lectin-carbohydrate interfaces were compared with those characterizing a set of 32 protein homodimers.
T7 949-1096 Sentence denotes Overall, the analysis shows that the stereochemical bases of lectin-carbohydrate and protein-protein interfaces differ drastically from each other.
T8 1097-1286 Sentence denotes In comparison with protein-protein complexes, lectin-carbohydrate interfaces have superior packing efficiency, better hydrogen bonding stereochemistry, and higher interaction cooperativity.
T9 1287-1369 Sentence denotes A similar conclusion holds in the comparison with protein-protein heterocomplexes.
T10 1370-1619 Sentence denotes We propose that the energetic consequence of this better interaction geometry is a larger decrease in free energy per unit of area buried, feature that enables lectins and carbohydrates to form stable complexes with relatively small interface areas.
T11 1620-1784 Sentence denotes These observations lend support to the emerging notion that systems differing from each other in their stereochemical metrics may rely on different energetic bases.
T1 0-103 Sentence denotes Stereochemical metrics of lectin-carbohydrate interactions: comparison with protein-protein interfaces.
T2 104-362 Sentence denotes A global census of stereochemical metrics including interface size, hydropathy, amino acid propensities, packing and hydrogen bonding was carried out on 32 x-ray-elucidated structures of lectin-carbohydrate complexes covering eight different lectin families.
T3 363-467 Sentence denotes It is shown that the interactions at primary binding subsites are more efficient than at other subsites.
T4 468-611 Sentence denotes Another salient behavior found for primary subsites was a marked negative correlation between the interface size and the polar surface content.
T5 612-816 Sentence denotes It is noteworthy that this demographic rule is delineated by lectins with unrelated phylogenetic origin, indicating that independent interface architectures have evolved through common optimization paths.
T6 817-948 Sentence denotes The structural properties of lectin-carbohydrate interfaces were compared with those characterizing a set of 32 protein homodimers.
T7 949-1096 Sentence denotes Overall, the analysis shows that the stereochemical bases of lectin-carbohydrate and protein-protein interfaces differ drastically from each other.
T8 1097-1286 Sentence denotes In comparison with protein-protein complexes, lectin-carbohydrate interfaces have superior packing efficiency, better hydrogen bonding stereochemistry, and higher interaction cooperativity.
T9 1287-1369 Sentence denotes A similar conclusion holds in the comparison with protein-protein heterocomplexes.
T10 1370-1619 Sentence denotes We propose that the energetic consequence of this better interaction geometry is a larger decrease in free energy per unit of area buried, feature that enables lectins and carbohydrates to form stable complexes with relatively small interface areas.
T11 1620-1784 Sentence denotes These observations lend support to the emerging notion that systems differing from each other in their stereochemical metrics may rely on different energetic bases.

GlycoBiology-FMA

Id Subject Object Predicate Lexical cue
_T1 33-45 FMAID:82737 denotes carbohydrate
_T2 33-45 FMAID:197276 denotes carbohydrate
_T3 76-83 FMAID:165447 denotes protein
_T4 76-83 FMAID:67257 denotes protein
_T5 76-91 FMAID:231313 denotes protein-protein
_T6 76-91 FMAID:165475 denotes protein-protein
_T7 76-91 FMAID:165476 denotes protein-protein
_T8 76-91 FMAID:231312 denotes protein-protein
_T9 76-91 FMAID:166112 denotes protein-protein
_T10 76-91 FMAID:165438 denotes protein-protein
_T11 76-91 FMAID:62925 denotes protein-protein
_T12 76-91 FMAID:165430 denotes protein-protein
_T13 76-91 FMAID:231303 denotes protein-protein
_T14 76-91 FMAID:231302 denotes protein-protein
_T15 76-91 FMAID:199792 denotes protein-protein
_T16 76-91 FMAID:167256 denotes protein-protein
_T17 76-91 FMAID:165470 denotes protein-protein
_T18 76-91 FMAID:165866 denotes protein-protein
_T19 76-91 FMAID:67119 denotes protein-protein
_T20 76-91 FMAID:90067 denotes protein-protein
_T21 76-91 FMAID:62290 denotes protein-protein
_T22 76-91 FMAID:63169 denotes protein-protein
_T23 76-91 FMAID:165434 denotes protein-protein
_T24 76-91 FMAID:167415 denotes protein-protein
_T25 76-91 FMAID:85438 denotes protein-protein
_T26 76-91 FMAID:198030 denotes protein-protein
_T27 76-91 FMAID:174224 denotes protein-protein
_T28 76-91 FMAID:72158 denotes protein-protein
_T29 76-91 FMAID:231305 denotes protein-protein
_T30 76-91 FMAID:231304 denotes protein-protein
_T31 76-91 FMAID:165914 denotes protein-protein
_T32 76-91 FMAID:62378 denotes protein-protein
_T33 76-91 FMAID:67906 denotes protein-protein
_T34 84-91 FMAID:165447 denotes protein
_T35 84-91 FMAID:67257 denotes protein
_T36 184-194 FMAID:82739 denotes amino acid
_T37 184-194 FMAID:196728 denotes amino acid
_T38 217-229 FMAID:83375 denotes and hydrogen
_T39 217-229 FMAID:197660 denotes and hydrogen
_T40 298-310 FMAID:82737 denotes carbohydrate
_T41 298-310 FMAID:197276 denotes carbohydrate
_T42 595-602 FMAID:50594 denotes surface
_T43 595-602 FMAID:146300 denotes surface
_T44 853-865 FMAID:197276 denotes carbohydrate
_T45 853-865 FMAID:82737 denotes carbohydrate
_T46 929-936 FMAID:67257 denotes protein
_T47 929-936 FMAID:165447 denotes protein
_T48 1017-1029 FMAID:82737 denotes carbohydrate
_T49 1017-1029 FMAID:197276 denotes carbohydrate
_T50 1030-1049 FMAID:231302 denotes and protein-protein
_T51 1030-1049 FMAID:72158 denotes and protein-protein
_T52 1030-1049 FMAID:174224 denotes and protein-protein
_T53 1030-1049 FMAID:231303 denotes and protein-protein
_T54 1030-1049 FMAID:67140 denotes and protein-protein
_T55 1030-1049 FMAID:67119 denotes and protein-protein
_T56 1030-1049 FMAID:165433 denotes and protein-protein
_T57 1030-1049 FMAID:165911 denotes and protein-protein
_T58 1030-1049 FMAID:62376 denotes and protein-protein
_T59 1030-1049 FMAID:67132 denotes and protein-protein
_T60 1030-1049 FMAID:165430 denotes and protein-protein
_T61 1030-1049 FMAID:165437 denotes and protein-protein
_T62 1034-1041 FMAID:165447 denotes protein
_T63 1034-1041 FMAID:67257 denotes protein
_T64 1034-1049 FMAID:165470 denotes protein-protein
_T65 1034-1049 FMAID:165476 denotes protein-protein
_T66 1034-1049 FMAID:67906 denotes protein-protein
_T67 1034-1049 FMAID:199792 denotes protein-protein
_T68 1034-1049 FMAID:85438 denotes protein-protein
_T69 1034-1049 FMAID:165475 denotes protein-protein
_T70 1034-1049 FMAID:231313 denotes protein-protein
_T71 1034-1049 FMAID:231312 denotes protein-protein
_T72 1034-1049 FMAID:231303 denotes protein-protein
_T73 1034-1049 FMAID:165866 denotes protein-protein
_T74 1034-1049 FMAID:166112 denotes protein-protein
_T75 1034-1049 FMAID:231302 denotes protein-protein
_T76 1034-1049 FMAID:62290 denotes protein-protein
_T77 1034-1049 FMAID:165438 denotes protein-protein
_T78 1034-1049 FMAID:90067 denotes protein-protein
_T79 1034-1049 FMAID:167256 denotes protein-protein
_T80 1034-1049 FMAID:62925 denotes protein-protein
_T81 1034-1049 FMAID:62378 denotes protein-protein
_T82 1034-1049 FMAID:165914 denotes protein-protein
_T83 1034-1049 FMAID:198030 denotes protein-protein
_T84 1034-1049 FMAID:231305 denotes protein-protein
_T85 1034-1049 FMAID:165434 denotes protein-protein
_T86 1034-1049 FMAID:63169 denotes protein-protein
_T87 1034-1049 FMAID:167415 denotes protein-protein
_T88 1034-1049 FMAID:231304 denotes protein-protein
_T89 1042-1049 FMAID:165447 denotes protein
_T90 1042-1049 FMAID:67257 denotes protein
_T91 1100-1141 FMAID:62847 denotes comparison with protein-protein complexes
_T92 1100-1141 FMAID:167139 denotes comparison with protein-protein complexes
_T93 1116-1123 FMAID:165447 denotes protein
_T94 1116-1123 FMAID:67257 denotes protein
_T95 1116-1141 FMAID:199982 denotes protein-protein complexes
_T96 1116-1141 FMAID:85558 denotes protein-protein complexes
_T97 1116-1141 FMAID:210763 denotes protein-protein complexes
_T98 1116-1141 FMAID:199026 denotes protein-protein complexes
_T99 1116-1141 FMAID:165839 denotes protein-protein complexes
_T100 1116-1141 FMAID:67889 denotes protein-protein complexes
_T101 1116-1141 FMAID:84762 denotes protein-protein complexes
_T102 1124-1131 FMAID:67257 denotes protein
_T103 1124-1131 FMAID:165447 denotes protein
_T104 1124-1141 FMAID:199981 denotes protein complexes
_T105 1124-1141 FMAID:85557 denotes protein complexes
_T106 1124-1141 FMAID:165866 denotes protein complexes
_T107 1124-1141 FMAID:67906 denotes protein complexes
_T108 1150-1162 FMAID:82737 denotes carbohydrate
_T109 1150-1162 FMAID:197276 denotes carbohydrate
_T110 1179-1187 FMAID:174814 denotes superior
_T111 1179-1187 FMAID:274208 denotes superior
_T112 1179-1187 FMAID:30337 denotes superior
_T113 1337-1344 FMAID:67257 denotes protein
_T114 1337-1344 FMAID:165447 denotes protein
_T115 1337-1368 FMAID:85557 denotes protein-protein heterocomplexes
_T116 1337-1368 FMAID:199981 denotes protein-protein heterocomplexes
_T117 1345-1352 FMAID:165447 denotes protein
_T118 1345-1352 FMAID:67257 denotes protein
_T119 1345-1368 FMAID:165866 denotes protein heterocomplexes
_T120 1345-1368 FMAID:67906 denotes protein heterocomplexes
_T121 1542-1555 FMAID:82737 denotes carbohydrates
_T122 1542-1555 FMAID:197276 denotes carbohydrates

GlycoBiology-NCBITAXON

Id Subject Object Predicate Lexical cue
T1 76-91 http://purl.bioontology.org/ontology/NCBITAXON/66543 denotes protein-protein
T2 76-91 http://purl.bioontology.org/ontology/NCBITAXON/66322 denotes protein-protein
T3 76-91 http://purl.bioontology.org/ontology/NCBITAXON/415014 denotes protein-protein
T4 484-492 http://purl.bioontology.org/ontology/STY/T053 denotes behavior
T5 1034-1049 http://purl.bioontology.org/ontology/NCBITAXON/66322 denotes protein-protein
T6 1034-1049 http://purl.bioontology.org/ontology/NCBITAXON/415014 denotes protein-protein
T7 1034-1049 http://purl.bioontology.org/ontology/NCBITAXON/66543 denotes protein-protein
T8 1116-1131 http://purl.bioontology.org/ontology/NCBITAXON/66543 denotes protein-protein
T9 1116-1131 http://purl.bioontology.org/ontology/NCBITAXON/66322 denotes protein-protein
T10 1116-1131 http://purl.bioontology.org/ontology/NCBITAXON/415014 denotes protein-protein
T11 1337-1352 http://purl.bioontology.org/ontology/NCBITAXON/415014 denotes protein-protein
T12 1337-1352 http://purl.bioontology.org/ontology/NCBITAXON/66543 denotes protein-protein
T13 1337-1352 http://purl.bioontology.org/ontology/NCBITAXON/66322 denotes protein-protein
T14 1439-1447 http://purl.bioontology.org/ontology/NCBITAXON/1369226 denotes geometry
T15 1496-1500 http://purl.bioontology.org/ontology/NCBITAXON/293505 denotes area
T16 1613-1618 http://purl.bioontology.org/ontology/NCBITAXON/293505 denotes areas

GO-BP

Id Subject Object Predicate Lexical cue
T1 484-492 http://purl.obolibrary.org/obo/GO_0007610 denotes behavior

GO-MF

Id Subject Object Predicate Lexical cue
T1 408-415 http://purl.obolibrary.org/obo/GO_0070026 denotes binding
T2 408-415 http://purl.obolibrary.org/obo/GO_0003680 denotes binding
T3 408-415 http://purl.obolibrary.org/obo/GO_0017091 denotes binding
T4 408-415 http://purl.obolibrary.org/obo/GO_0005488 denotes binding

GO-CC

Id Subject Object Predicate Lexical cue
T1 1124-1141 http://purl.obolibrary.org/obo/GO_0043234 denotes protein complexes

EDAM-topics

Id Subject Object Predicate Lexical cue
T1 33-45 http://edamontology.org/topic_0152 denotes carbohydrate
T2 46-58 http://edamontology.org/topic_0602 denotes interactions
T3 76-83 http://edamontology.org/topic_0078 denotes protein
T4 76-91 http://edamontology.org/topic_0820 denotes protein-protein
T5 76-91 http://edamontology.org/topic_0140 denotes protein-protein
T6 76-91 http://edamontology.org/topic_0595 denotes protein-protein
T7 76-91 http://edamontology.org/topic_0130 denotes protein-protein
T8 76-91 http://edamontology.org/topic_2830 denotes protein-protein
T9 76-91 http://edamontology.org/topic_3043 denotes protein-protein
T10 76-91 http://edamontology.org/topic_0078 denotes protein-protein
T11 76-91 http://edamontology.org/topic_0635 denotes protein-protein
T12 76-91 http://edamontology.org/topic_0157 denotes protein-protein
T13 76-91 http://edamontology.org/topic_0150 denotes protein-protein
T14 76-91 http://edamontology.org/topic_3120 denotes protein-protein
T15 76-91 http://edamontology.org/topic_2232 denotes protein-protein
T16 76-91 http://edamontology.org/topic_0123 denotes protein-protein
T17 76-91 http://edamontology.org/topic_0601 denotes protein-protein
T18 76-91 http://edamontology.org/topic_0176 denotes protein-protein
T19 76-91 http://edamontology.org/topic_0736 denotes protein-protein
T20 76-91 http://edamontology.org/topic_0623 denotes protein-protein
T21 76-91 http://edamontology.org/topic_0724 denotes protein-protein
T22 76-91 http://edamontology.org/topic_0108 denotes protein-protein
T23 76-91 http://edamontology.org/topic_0121 denotes protein-protein
T24 76-91 http://edamontology.org/topic_2225 denotes protein-protein
T25 76-91 http://edamontology.org/topic_3539 denotes protein-protein
T26 76-102 http://edamontology.org/topic_3526 denotes protein-protein interfaces
T27 76-102 http://edamontology.org/topic_0128 denotes protein-protein interfaces
T28 76-102 http://edamontology.org/topic_0147 denotes protein-protein interfaces
T29 76-102 http://edamontology.org/topic_0166 denotes protein-protein interfaces
T30 84-91 http://edamontology.org/topic_0078 denotes protein
T31 184-194 http://edamontology.org/topic_0154 denotes amino acid
T32 298-310 http://edamontology.org/topic_0152 denotes carbohydrate
T33 384-396 http://edamontology.org/topic_0602 denotes interactions
T34 696-708 http://edamontology.org/topic_3293 denotes phylogenetic
T35 853-865 http://edamontology.org/topic_0152 denotes carbohydrate
T36 929-936 http://edamontology.org/topic_0078 denotes protein
T37 1017-1029 http://edamontology.org/topic_0152 denotes carbohydrate
T38 1034-1041 http://edamontology.org/topic_0078 denotes protein
T39 1034-1049 http://edamontology.org/topic_0736 denotes protein-protein
T40 1034-1049 http://edamontology.org/topic_0623 denotes protein-protein
T41 1034-1049 http://edamontology.org/topic_0820 denotes protein-protein
T42 1034-1049 http://edamontology.org/topic_0130 denotes protein-protein
T43 1034-1049 http://edamontology.org/topic_0150 denotes protein-protein
T44 1034-1049 http://edamontology.org/topic_0123 denotes protein-protein
T45 1034-1049 http://edamontology.org/topic_2232 denotes protein-protein
T46 1034-1049 http://edamontology.org/topic_3043 denotes protein-protein
T47 1034-1049 http://edamontology.org/topic_3120 denotes protein-protein
T48 1034-1049 http://edamontology.org/topic_0601 denotes protein-protein
T49 1034-1049 http://edamontology.org/topic_0724 denotes protein-protein
T50 1034-1049 http://edamontology.org/topic_0635 denotes protein-protein
T51 1034-1049 http://edamontology.org/topic_3539 denotes protein-protein
T52 1034-1049 http://edamontology.org/topic_0140 denotes protein-protein
T53 1034-1049 http://edamontology.org/topic_0108 denotes protein-protein
T54 1034-1049 http://edamontology.org/topic_0078 denotes protein-protein
T55 1034-1049 http://edamontology.org/topic_0176 denotes protein-protein
T56 1034-1049 http://edamontology.org/topic_2830 denotes protein-protein
T57 1034-1049 http://edamontology.org/topic_0157 denotes protein-protein
T58 1034-1049 http://edamontology.org/topic_0595 denotes protein-protein
T59 1034-1049 http://edamontology.org/topic_0121 denotes protein-protein
T60 1034-1049 http://edamontology.org/topic_2225 denotes protein-protein
T61 1034-1060 http://edamontology.org/topic_0128 denotes protein-protein interfaces
T62 1034-1060 http://edamontology.org/topic_0166 denotes protein-protein interfaces
T63 1034-1060 http://edamontology.org/topic_3526 denotes protein-protein interfaces
T64 1034-1060 http://edamontology.org/topic_0147 denotes protein-protein interfaces
T65 1042-1049 http://edamontology.org/topic_0078 denotes protein
T66 1116-1123 http://edamontology.org/topic_0078 denotes protein
T67 1116-1131 http://edamontology.org/topic_2232 denotes protein-protein
T68 1116-1131 http://edamontology.org/topic_2830 denotes protein-protein
T69 1116-1131 http://edamontology.org/topic_0130 denotes protein-protein
T70 1116-1131 http://edamontology.org/topic_0820 denotes protein-protein
T71 1116-1131 http://edamontology.org/topic_0140 denotes protein-protein
T72 1116-1131 http://edamontology.org/topic_0166 denotes protein-protein
T73 1116-1131 http://edamontology.org/topic_0108 denotes protein-protein
T74 1116-1131 http://edamontology.org/topic_0736 denotes protein-protein
T75 1116-1131 http://edamontology.org/topic_0121 denotes protein-protein
T76 1116-1131 http://edamontology.org/topic_0176 denotes protein-protein
T77 1116-1131 http://edamontology.org/topic_0623 denotes protein-protein
T78 1116-1131 http://edamontology.org/topic_0078 denotes protein-protein
T79 1116-1131 http://edamontology.org/topic_3539 denotes protein-protein
T80 1116-1131 http://edamontology.org/topic_0724 denotes protein-protein
T81 1116-1131 http://edamontology.org/topic_0601 denotes protein-protein
T82 1116-1131 http://edamontology.org/topic_3120 denotes protein-protein
T83 1116-1131 http://edamontology.org/topic_0150 denotes protein-protein
T84 1116-1131 http://edamontology.org/topic_0123 denotes protein-protein
T85 1116-1131 http://edamontology.org/topic_0635 denotes protein-protein
T86 1116-1131 http://edamontology.org/topic_0157 denotes protein-protein
T87 1116-1131 http://edamontology.org/topic_2225 denotes protein-protein
T88 1116-1131 http://edamontology.org/topic_0595 denotes protein-protein
T89 1116-1131 http://edamontology.org/topic_3043 denotes protein-protein
T90 1124-1131 http://edamontology.org/topic_0078 denotes protein
T91 1150-1162 http://edamontology.org/topic_0152 denotes carbohydrate
T92 1260-1271 http://edamontology.org/topic_0602 denotes interaction
T93 1337-1344 http://edamontology.org/topic_0078 denotes protein
T94 1337-1352 http://edamontology.org/topic_0595 denotes protein-protein
T95 1337-1352 http://edamontology.org/topic_0157 denotes protein-protein
T96 1337-1352 http://edamontology.org/topic_2830 denotes protein-protein
T97 1337-1352 http://edamontology.org/topic_0123 denotes protein-protein
T98 1337-1352 http://edamontology.org/topic_0635 denotes protein-protein
T99 1337-1352 http://edamontology.org/topic_0601 denotes protein-protein
T100 1337-1352 http://edamontology.org/topic_0140 denotes protein-protein
T101 1337-1352 http://edamontology.org/topic_3043 denotes protein-protein
T102 1337-1352 http://edamontology.org/topic_0130 denotes protein-protein
T103 1337-1352 http://edamontology.org/topic_0736 denotes protein-protein
T104 1337-1352 http://edamontology.org/topic_2232 denotes protein-protein
T105 1337-1352 http://edamontology.org/topic_0078 denotes protein-protein
T106 1337-1352 http://edamontology.org/topic_0820 denotes protein-protein
T107 1337-1352 http://edamontology.org/topic_0623 denotes protein-protein
T108 1337-1352 http://edamontology.org/topic_2225 denotes protein-protein
T109 1337-1352 http://edamontology.org/topic_0121 denotes protein-protein
T110 1337-1352 http://edamontology.org/topic_0108 denotes protein-protein
T111 1337-1352 http://edamontology.org/topic_0166 denotes protein-protein
T112 1337-1352 http://edamontology.org/topic_0176 denotes protein-protein
T113 1337-1352 http://edamontology.org/topic_3539 denotes protein-protein
T114 1337-1352 http://edamontology.org/topic_0150 denotes protein-protein
T115 1337-1352 http://edamontology.org/topic_3120 denotes protein-protein
T116 1337-1352 http://edamontology.org/topic_0724 denotes protein-protein
T117 1345-1352 http://edamontology.org/topic_0078 denotes protein
T118 1427-1438 http://edamontology.org/topic_0602 denotes interaction
T119 1542-1555 http://edamontology.org/topic_0152 denotes carbohydrates

EDAM-DFO

Id Subject Object Predicate Lexical cue
T1 60-70 http://edamontology.org/operation_2424 denotes comparison
T2 76-83 http://edamontology.org/data_1467 denotes protein
T3 76-83 http://edamontology.org/format_1208 denotes protein
T4 76-91 http://edamontology.org/data_0897 denotes protein-protein
T5 76-91 http://edamontology.org/data_0875 denotes protein-protein
T6 76-91 http://edamontology.org/data_1359 denotes protein-protein
T7 76-91 http://edamontology.org/operation_0302 denotes protein-protein
T8 76-91 http://edamontology.org/data_1524 denotes protein-protein
T9 76-91 http://edamontology.org/operation_0331 denotes protein-protein
T10 76-91 http://edamontology.org/format_1219 denotes protein-protein
T11 76-91 http://edamontology.org/data_2524 denotes protein-protein
T12 76-91 http://edamontology.org/operation_0330 denotes protein-protein
T13 76-91 http://edamontology.org/data_2976 denotes protein-protein
T14 76-91 http://edamontology.org/data_1756 denotes protein-protein
T15 76-91 http://edamontology.org/data_0896 denotes protein-protein
T16 76-91 http://edamontology.org/data_2877 denotes protein-protein
T17 76-91 http://edamontology.org/data_3145 denotes protein-protein
T18 76-91 http://edamontology.org/data_2907 denotes protein-protein
T19 76-91 http://edamontology.org/data_1755 denotes protein-protein
T20 76-91 http://edamontology.org/data_1529 denotes protein-protein
T21 76-91 http://edamontology.org/operation_0390 denotes protein-protein
T22 76-91 http://edamontology.org/data_1009 denotes protein-protein
T23 76-91 http://edamontology.org/operation_0322 denotes protein-protein
T24 76-91 http://edamontology.org/operation_0477 denotes protein-protein
T25 76-91 http://edamontology.org/data_3154 denotes protein-protein
T26 76-91 http://edamontology.org/operation_0478 denotes protein-protein
T27 76-91 http://edamontology.org/data_1468 denotes protein-protein
T28 76-91 http://edamontology.org/data_2980 denotes protein-protein
T29 76-91 http://edamontology.org/operation_2502 denotes protein-protein
T30 76-91 http://edamontology.org/data_3153 denotes protein-protein
T31 76-91 http://edamontology.org/data_2327 denotes protein-protein
T32 76-91 http://edamontology.org/data_1277 denotes protein-protein
T33 76-102 http://edamontology.org/data_1074 denotes protein-protein interfaces
T34 76-102 http://edamontology.org/operation_2492 denotes protein-protein interfaces
T35 84-91 http://edamontology.org/format_1208 denotes protein
T36 84-91 http://edamontology.org/data_1467 denotes protein
T37 184-207 http://edamontology.org/data_2016 denotes amino acid propensities
T38 277-287 http://edamontology.org/data_0883 denotes structures
T39 542-553 http://edamontology.org/operation_3465 denotes correlation
T40 821-831 http://edamontology.org/data_0883 denotes structural
T41 929-936 http://edamontology.org/format_1208 denotes protein
T42 929-936 http://edamontology.org/data_1467 denotes protein
T43 962-970 http://edamontology.org/operation_2945 denotes analysis
T44 1034-1041 http://edamontology.org/format_1208 denotes protein
T45 1034-1041 http://edamontology.org/data_1467 denotes protein
T46 1034-1049 http://edamontology.org/data_0897 denotes protein-protein
T47 1034-1049 http://edamontology.org/data_3154 denotes protein-protein
T48 1034-1049 http://edamontology.org/operation_0477 denotes protein-protein
T49 1034-1049 http://edamontology.org/operation_0330 denotes protein-protein
T50 1034-1049 http://edamontology.org/operation_2997 denotes protein-protein
T51 1034-1049 http://edamontology.org/data_0896 denotes protein-protein
T52 1034-1049 http://edamontology.org/data_1756 denotes protein-protein
T53 1034-1049 http://edamontology.org/data_3145 denotes protein-protein
T54 1034-1049 http://edamontology.org/data_2877 denotes protein-protein
T55 1034-1049 http://edamontology.org/format_1219 denotes protein-protein
T56 1034-1049 http://edamontology.org/data_0875 denotes protein-protein
T57 1034-1049 http://edamontology.org/data_2524 denotes protein-protein
T58 1034-1049 http://edamontology.org/data_2980 denotes protein-protein
T59 1034-1049 http://edamontology.org/operation_0322 denotes protein-protein
T60 1034-1049 http://edamontology.org/data_2907 denotes protein-protein
T61 1034-1049 http://edamontology.org/operation_0478 denotes protein-protein
T62 1034-1049 http://edamontology.org/operation_0331 denotes protein-protein
T63 1034-1049 http://edamontology.org/data_3153 denotes protein-protein
T64 1034-1049 http://edamontology.org/data_1755 denotes protein-protein
T65 1034-1049 http://edamontology.org/data_1468 denotes protein-protein
T66 1034-1049 http://edamontology.org/data_1529 denotes protein-protein
T67 1034-1049 http://edamontology.org/data_1359 denotes protein-protein
T68 1034-1049 http://edamontology.org/data_1277 denotes protein-protein
T69 1034-1049 http://edamontology.org/data_2976 denotes protein-protein
T70 1034-1049 http://edamontology.org/data_1524 denotes protein-protein
T71 1034-1049 http://edamontology.org/operation_0390 denotes protein-protein
T72 1034-1049 http://edamontology.org/data_2327 denotes protein-protein
T73 1034-1049 http://edamontology.org/data_1009 denotes protein-protein
T74 1034-1049 http://edamontology.org/operation_2502 denotes protein-protein
T75 1034-1049 http://edamontology.org/operation_0302 denotes protein-protein
T76 1034-1060 http://edamontology.org/data_1074 denotes protein-protein interfaces
T77 1034-1060 http://edamontology.org/operation_2492 denotes protein-protein interfaces
T78 1042-1049 http://edamontology.org/format_1208 denotes protein
T79 1042-1049 http://edamontology.org/data_1467 denotes protein
T80 1100-1110 http://edamontology.org/operation_2424 denotes comparison
T81 1116-1123 http://edamontology.org/format_1208 denotes protein
T82 1116-1123 http://edamontology.org/data_1467 denotes protein
T83 1124-1131 http://edamontology.org/format_1208 denotes protein
T84 1124-1131 http://edamontology.org/data_1467 denotes protein
T85 1124-1141 http://edamontology.org/data_2877 denotes protein complexes
T86 1124-1141 http://edamontology.org/data_1461 denotes protein complexes
T87 1321-1331 http://edamontology.org/operation_2424 denotes comparison
T88 1337-1344 http://edamontology.org/format_1208 denotes protein
T89 1337-1344 http://edamontology.org/data_1467 denotes protein
T90 1337-1368 http://edamontology.org/data_1461 denotes protein-protein heterocomplexes
T91 1345-1352 http://edamontology.org/format_1208 denotes protein
T92 1345-1352 http://edamontology.org/data_1467 denotes protein
T93 1345-1368 http://edamontology.org/data_2877 denotes protein heterocomplexes
T94 1509-1516 http://edamontology.org/data_1255 denotes feature

Lectin-Jamboree

Id Subject Object Predicate Lexical cue
T1 26-32 lectin denotes lectin
T2 291-297 lectin denotes lectin
T3 346-352 lectin denotes lectin
T4 673-680 lectin denotes lectins
T5 846-852 lectin denotes lectin
T6 1010-1016 lectin denotes lectin
T7 1143-1149 lectin denotes lectin
T8 1530-1537 lectin denotes lectins

Lectin-Jamboree-Sentence

Id Subject Object Predicate Lexical cue
T1 0-103 Sentence denotes Stereochemical metrics of lectin-carbohydrate interactions: comparison with protein-protein interfaces.
T2 104-362 Sentence denotes A global census of stereochemical metrics including interface size, hydropathy, amino acid propensities, packing and hydrogen bonding was carried out on 32 x-ray-elucidated structures of lectin-carbohydrate complexes covering eight different lectin families.
T3 363-467 Sentence denotes It is shown that the interactions at primary binding subsites are more efficient than at other subsites.
T4 468-611 Sentence denotes Another salient behavior found for primary subsites was a marked negative correlation between the interface size and the polar surface content.
T5 612-816 Sentence denotes It is noteworthy that this demographic rule is delineated by lectins with unrelated phylogenetic origin, indicating that independent interface architectures have evolved through common optimization paths.
T6 817-948 Sentence denotes The structural properties of lectin-carbohydrate interfaces were compared with those characterizing a set of 32 protein homodimers.
T7 949-1096 Sentence denotes Overall, the analysis shows that the stereochemical bases of lectin-carbohydrate and protein-protein interfaces differ drastically from each other.
T8 1097-1286 Sentence denotes In comparison with protein-protein complexes, lectin-carbohydrate interfaces have superior packing efficiency, better hydrogen bonding stereochemistry, and higher interaction cooperativity.
T9 1287-1369 Sentence denotes A similar conclusion holds in the comparison with protein-protein heterocomplexes.
T10 1370-1619 Sentence denotes We propose that the energetic consequence of this better interaction geometry is a larger decrease in free energy per unit of area buried, feature that enables lectins and carbohydrates to form stable complexes with relatively small interface areas.
T11 1620-1784 Sentence denotes These observations lend support to the emerging notion that systems differing from each other in their stereochemical metrics may rely on different energetic bases.