
PubMed:10988300
Annnotations
ggdb-test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 71-113 | https://acgg.asia/db/ggdb/info/gg045 | denotes | N-acetylgalactosamine-4-O-sulfotransferase |
T2 | 460-472 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T3 | 673-695 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 sulfotransferase |
T4 | 697-705 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T5 | 708-720 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T6 | 746-754 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T7 | 766-798 | https://acgg.asia/db/ggdb/info/gg036 | denotes | chondroitin 4-sulfotransferase 1 |
T8 | 800-806 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
T9 | 819-851 | https://acgg.asia/db/ggdb/info/gg037 | denotes | chondroitin 4-sulfotransferase 2 |
T10 | 853-859 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
T11 | 853-857 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
T12 | 1019-1031 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T13 | 1195-1203 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T14 | 1205-1211 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
T15 | 1217-1223 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
T16 | 1217-1221 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
T17 | 1252-1264 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T18 | 1364-1376 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T19 | 1508-1520 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T20 | 1615-1627 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T21 | 1901-1913 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 71-92 | Glycan_Motif | denotes | N-acetylgalactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB |
T2 | 418-439 | Glycan_Motif | denotes | N-acetylgalactosamine | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G27025MB |
T3 | 673-678 | Glycan_Motif | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD |
T4 | 697-702 | Glycan_Motif | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD |
T5 | 746-751 | Glycan_Motif | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD |
T6 | 766-777 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T7 | 819-830 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T8 | 1195-1200 | Glycan_Motif | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G54406UD |
T9 | 1324-1335 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T10 | 1466-1477 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
GGDB-2020
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 71-113 | https://acgg.asia/db/ggdb/info/gg045 | denotes | N-acetylgalactosamine-4-O-sulfotransferase |
T2 | 460-472 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T3 | 673-695 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 sulfotransferase |
T4 | 697-705 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T5 | 708-720 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T6 | 746-754 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T7 | 766-798 | https://acgg.asia/db/ggdb/info/gg036 | denotes | chondroitin 4-sulfotransferase 1 |
T8 | 800-806 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
T9 | 819-851 | https://acgg.asia/db/ggdb/info/gg037 | denotes | chondroitin 4-sulfotransferase 2 |
T10 | 853-859 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
T11 | 853-857 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
T12 | 1019-1031 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T13 | 1195-1203 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
T14 | 1205-1211 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
T15 | 1217-1223 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
T16 | 1217-1221 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
T17 | 1252-1264 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T18 | 1364-1376 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T19 | 1508-1520 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T20 | 1615-1627 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
T21 | 1901-1913 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-114 | Sentence | denotes | Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. |
T2 | 115-305 | Sentence | denotes | N-Linked oligosaccharides terminating with the sequence SO(4)-4-GalNAcbeta1,4GlcNAcbeta1,2Manalpha are present on the pituitary hormones lutropin (LH), thyrotropin, and pro-opiomelanocortin. |
T3 | 306-398 | Sentence | denotes | The sulfated structures on LH are essential for expression of its biologic function in vivo. |
T4 | 399-707 | Sentence | denotes | We have cloned the N-acetylgalactosamine-4-sulfotransferase (GalNAc-4-ST1, GenBank(TM) accession number ), which mediates sulfate addition to the N-linked oligosaccharides on LH and other pituitary glycoproteins with terminal (beta1,4-linked GalNAc based on its homology to HNK-1 sulfotransferase (HNK-1 ST). |
T5 | 708-861 | Sentence | denotes | GalNAc-4-ST1 displays 23% identity to HNK-1 ST and 28% to chondroitin 4-sulfotransferase 1 (C4ST-1) and 26% to chondroitin 4-sulfotransferase 2 (C4ST-2). |
T6 | 862-1018 | Sentence | denotes | The cDNA predicts a type II transmembrane protein of 424 amino acids with four potential N-linked glycosylation sites and a single membrane-spanning domain. |
T7 | 1019-1096 | Sentence | denotes | GalNAc-4-ST1 has putative 5'-phosphosulfonate and 3'-phosphate binding sites. |
T8 | 1097-1224 | Sentence | denotes | Three more carboxyl-terminal regions of unknown function also show a high degree of identity with HNK-1 ST, C4ST-1, and C4ST-2. |
T9 | 1225-1478 | Sentence | denotes | The membrane-bound form of GalNAc-4-ST1 transfers sulfate to GalNAcbeta1, 4GlcNAcbeta-R but not to chondroitin, whereas truncated forms of GalNAc-4-ST1 that are released into the medium transfer sulfate to both GalNAcbeta1,4GlcNAcbeta-R and chondroitin. |
T10 | 1479-1614 | Sentence | denotes | The first 118 amino acids of GalNAc-4-ST1 appear to contribute to both its activity and specificity for terminal beta1,4-linked GalNAc. |
T11 | 1615-1768 | Sentence | denotes | GalNAc-4-ST1 also efficiently transfers sulfate to N-linked oligosaccharides on native LH and other glycoproteins terminating with beta1,4-linked GalNAc. |
T12 | 1769-1896 | Sentence | denotes | A single transcript of 2.4 kilobases is most highly expressed in the pituitary and other regions of the central nervous system. |
T13 | 1897-1958 | Sentence | denotes | The GalNAc-4-ST1 gene is located on human chromosome 19q13.1. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 71-92 | https://glytoucan.org/Structures/Glycans/G27025MB | denotes | N-acetylgalactosamine |
T2 | 418-439 | https://glytoucan.org/Structures/Glycans/G27025MB | denotes | N-acetylgalactosamine |
T3 | 673-678 | https://glytoucan.org/Structures/Glycans/G54406UD | denotes | HNK-1 |
T4 | 697-702 | https://glytoucan.org/Structures/Glycans/G54406UD | denotes | HNK-1 |
T5 | 746-751 | https://glytoucan.org/Structures/Glycans/G54406UD | denotes | HNK-1 |
T6 | 766-777 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T7 | 819-830 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T8 | 1195-1200 | https://glytoucan.org/Structures/Glycans/G54406UD | denotes | HNK-1 |
T9 | 1324-1335 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T10 | 1466-1477 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 673-678 | http://www.glycoepitope.jp/epitopes/EP0001 | denotes | HNK-1 |
T2 | 697-702 | http://www.glycoepitope.jp/epitopes/EP0001 | denotes | HNK-1 |
T3 | 746-751 | http://www.glycoepitope.jp/epitopes/EP0001 | denotes | HNK-1 |
T4 | 766-777 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T5 | 819-830 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T6 | 1195-1200 | http://www.glycoepitope.jp/epitopes/EP0001 | denotes | HNK-1 |
T7 | 1324-1335 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T8 | 1466-1477 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 40-49 | http://purl.obolibrary.org/obo/MAT_0000077 | denotes | pituitary |
T2 | 233-242 | http://purl.obolibrary.org/obo/MAT_0000077 | denotes | pituitary |
T3 | 587-596 | http://purl.obolibrary.org/obo/MAT_0000077 | denotes | pituitary |
T4 | 1838-1847 | http://purl.obolibrary.org/obo/MAT_0000077 | denotes | pituitary |
T5 | 1873-1895 | http://purl.obolibrary.org/obo/MAT_0000457 | denotes | central nervous system |
T6 | 1881-1895 | http://purl.obolibrary.org/obo/MAT_0000026 | denotes | nervous system |
glycogenes
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
PD-GlycoGenes20190927-B_T1 | 71-113 | https://acgg.asia/db/ggdb/info/gg046 | denotes | N-acetylgalactosamine-4-O-sulfotransferase |
PD-GlycoGenes20190927-B_T2 | 71-113 | https://acgg.asia/db/ggdb/info/gg045 | denotes | N-acetylgalactosamine-4-O-sulfotransferase |
PD-GlycoGenes20190927-B_T3 | 418-458 | https://acgg.asia/db/ggdb/info/gg046 | denotes | N-acetylgalactosamine-4-sulfotransferase |
PD-GlycoGenes20190927-B_T4 | 418-458 | https://acgg.asia/db/ggdb/info/gg045 | denotes | N-acetylgalactosamine-4-sulfotransferase |
PD-GlycoGenes20190927-B_T5 | 460-472 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T6 | 673-695 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 sulfotransferase |
PD-GlycoGenes20190927-B_T7 | 697-705 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
PD-GlycoGenes20190927-B_T8 | 708-720 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T9 | 746-754 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
PD-GlycoGenes20190927-B_T10 | 800-806 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
PD-GlycoGenes20190927-B_T11 | 853-859 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
PD-GlycoGenes20190927-B_T12 | 853-857 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
PD-GlycoGenes20190927-B_T13 | 887-889 | https://acgg.asia/db/ggdb/info/gg111 | denotes | II |
PD-GlycoGenes20190927-B_T14 | 1019-1031 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T15 | 1032-1035 | https://acgg.asia/db/ggdb/info/gg135 | denotes | has |
PD-GlycoGenes20190927-B_T16 | 1195-1203 | https://acgg.asia/db/ggdb/info/gg035 | denotes | HNK-1 ST |
PD-GlycoGenes20190927-B_T17 | 1205-1211 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST-1 |
PD-GlycoGenes20190927-B_T18 | 1217-1223 | https://acgg.asia/db/ggdb/info/gg037 | denotes | C4ST-2 |
PD-GlycoGenes20190927-B_T19 | 1217-1221 | https://acgg.asia/db/ggdb/info/gg036 | denotes | C4ST |
PD-GlycoGenes20190927-B_T20 | 1252-1264 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T21 | 1364-1376 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T22 | 1508-1520 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T23 | 1615-1627 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
PD-GlycoGenes20190927-B_T24 | 1901-1913 | https://acgg.asia/db/ggdb/info/gg045 | denotes | GalNAc-4-ST1 |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 40-49 | Disease | denotes | pituitary | http://purl.obolibrary.org/obo/MONDO_0021156 |
T2 | 233-242 | Disease | denotes | pituitary | http://purl.obolibrary.org/obo/MONDO_0021156 |
T3 | 587-596 | Disease | denotes | pituitary | http://purl.obolibrary.org/obo/MONDO_0021156 |
T4 | 1838-1847 | Disease | denotes | pituitary | http://purl.obolibrary.org/obo/MONDO_0021156 |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 40-49 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T2 | 233-242 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T3 | 587-596 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T4 | 1838-1847 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T5 | 1873-1895 | Body_part | denotes | central nervous system | http://purl.obolibrary.org/obo/MAT_0000457 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 460-466 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T2 | 641-647 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T3 | 673-678 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T4 | 697-702 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T5 | 708-714 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T6 | 746-751 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T7 | 766-777 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T8 | 819-830 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T9 | 1019-1025 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T10 | 1195-1200 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T11 | 1252-1258 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T12 | 1324-1335 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T13 | 1364-1370 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T14 | 1466-1477 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T15 | 1508-1514 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T16 | 1607-1613 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T17 | 1615-1621 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T18 | 1761-1767 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T19 | 1901-1907 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 673-678 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T2 | 697-702 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T3 | 746-751 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T4 | 766-777 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T5 | 819-830 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T6 | 1195-1200 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T7 | 1324-1335 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T8 | 1466-1477 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 40-49 | Disease | denotes | pituitary | MONDO:0021156 |
T2 | 233-242 | Disease | denotes | pituitary | MONDO:0021156 |
T3 | 587-596 | Disease | denotes | pituitary | MONDO:0021156 |
T4 | 1838-1847 | Disease | denotes | pituitary | MONDO:0021156 |
GlyCosmos15-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 40-49 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T2 | 233-242 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T3 | 587-596 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T4 | 890-903 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
T5 | 993-1001 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
T8 | 1229-1237 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
T11 | 1838-1847 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T12 | 1873-1895 | Body_part | denotes | central nervous system | http://purl.obolibrary.org/obo/UBERON_0001017 |
T13 | 1939-1949 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-114 | Sentence | denotes | Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. |
T2 | 115-305 | Sentence | denotes | N-Linked oligosaccharides terminating with the sequence SO(4)-4-GalNAcbeta1,4GlcNAcbeta1,2Manalpha are present on the pituitary hormones lutropin (LH), thyrotropin, and pro-opiomelanocortin. |
T3 | 306-398 | Sentence | denotes | The sulfated structures on LH are essential for expression of its biologic function in vivo. |
T4 | 399-707 | Sentence | denotes | We have cloned the N-acetylgalactosamine-4-sulfotransferase (GalNAc-4-ST1, GenBank(TM) accession number ), which mediates sulfate addition to the N-linked oligosaccharides on LH and other pituitary glycoproteins with terminal (beta1,4-linked GalNAc based on its homology to HNK-1 sulfotransferase (HNK-1 ST). |
T5 | 708-861 | Sentence | denotes | GalNAc-4-ST1 displays 23% identity to HNK-1 ST and 28% to chondroitin 4-sulfotransferase 1 (C4ST-1) and 26% to chondroitin 4-sulfotransferase 2 (C4ST-2). |
T6 | 862-1018 | Sentence | denotes | The cDNA predicts a type II transmembrane protein of 424 amino acids with four potential N-linked glycosylation sites and a single membrane-spanning domain. |
T7 | 1019-1096 | Sentence | denotes | GalNAc-4-ST1 has putative 5'-phosphosulfonate and 3'-phosphate binding sites. |
T8 | 1097-1224 | Sentence | denotes | Three more carboxyl-terminal regions of unknown function also show a high degree of identity with HNK-1 ST, C4ST-1, and C4ST-2. |
T9 | 1225-1478 | Sentence | denotes | The membrane-bound form of GalNAc-4-ST1 transfers sulfate to GalNAcbeta1, 4GlcNAcbeta-R but not to chondroitin, whereas truncated forms of GalNAc-4-ST1 that are released into the medium transfer sulfate to both GalNAcbeta1,4GlcNAcbeta-R and chondroitin. |
T10 | 1479-1614 | Sentence | denotes | The first 118 amino acids of GalNAc-4-ST1 appear to contribute to both its activity and specificity for terminal beta1,4-linked GalNAc. |
T11 | 1615-1768 | Sentence | denotes | GalNAc-4-ST1 also efficiently transfers sulfate to N-linked oligosaccharides on native LH and other glycoproteins terminating with beta1,4-linked GalNAc. |
T12 | 1769-1896 | Sentence | denotes | A single transcript of 2.4 kilobases is most highly expressed in the pituitary and other regions of the central nervous system. |
T13 | 1897-1958 | Sentence | denotes | The GalNAc-4-ST1 gene is located on human chromosome 19q13.1. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-114 | Sentence | denotes | Molecular cloning and expression of the pituitary glycoprotein hormone N-acetylgalactosamine-4-O-sulfotransferase. |
T2 | 115-305 | Sentence | denotes | N-Linked oligosaccharides terminating with the sequence SO(4)-4-GalNAcbeta1,4GlcNAcbeta1,2Manalpha are present on the pituitary hormones lutropin (LH), thyrotropin, and pro-opiomelanocortin. |
T3 | 306-398 | Sentence | denotes | The sulfated structures on LH are essential for expression of its biologic function in vivo. |
T4 | 399-707 | Sentence | denotes | We have cloned the N-acetylgalactosamine-4-sulfotransferase (GalNAc-4-ST1, GenBank(TM) accession number ), which mediates sulfate addition to the N-linked oligosaccharides on LH and other pituitary glycoproteins with terminal (beta1,4-linked GalNAc based on its homology to HNK-1 sulfotransferase (HNK-1 ST). |
T5 | 708-861 | Sentence | denotes | GalNAc-4-ST1 displays 23% identity to HNK-1 ST and 28% to chondroitin 4-sulfotransferase 1 (C4ST-1) and 26% to chondroitin 4-sulfotransferase 2 (C4ST-2). |
T6 | 862-1018 | Sentence | denotes | The cDNA predicts a type II transmembrane protein of 424 amino acids with four potential N-linked glycosylation sites and a single membrane-spanning domain. |
T7 | 1019-1096 | Sentence | denotes | GalNAc-4-ST1 has putative 5'-phosphosulfonate and 3'-phosphate binding sites. |
T8 | 1097-1224 | Sentence | denotes | Three more carboxyl-terminal regions of unknown function also show a high degree of identity with HNK-1 ST, C4ST-1, and C4ST-2. |
T9 | 1225-1478 | Sentence | denotes | The membrane-bound form of GalNAc-4-ST1 transfers sulfate to GalNAcbeta1, 4GlcNAcbeta-R but not to chondroitin, whereas truncated forms of GalNAc-4-ST1 that are released into the medium transfer sulfate to both GalNAcbeta1,4GlcNAcbeta-R and chondroitin. |
T10 | 1479-1614 | Sentence | denotes | The first 118 amino acids of GalNAc-4-ST1 appear to contribute to both its activity and specificity for terminal beta1,4-linked GalNAc. |
T11 | 1615-1768 | Sentence | denotes | GalNAc-4-ST1 also efficiently transfers sulfate to N-linked oligosaccharides on native LH and other glycoproteins terminating with beta1,4-linked GalNAc. |
T12 | 1769-1896 | Sentence | denotes | A single transcript of 2.4 kilobases is most highly expressed in the pituitary and other regions of the central nervous system. |
T13 | 1897-1958 | Sentence | denotes | The GalNAc-4-ST1 gene is located on human chromosome 19q13.1. |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 673-678 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T2 | 697-702 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T3 | 746-751 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T4 | 766-777 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T5 | 819-830 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T6 | 1195-1200 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HNK-1 | http://www.glycoepitope.jp/epitopes/EP0001 |
T7 | 1324-1335 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T8 | 1466-1477 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 1933-1938 | OrganismTaxon | denotes | human | 9606 |
GlyCosmos15-FMA
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 40-49 | Body_part | denotes | pituitary | FMA:13889 |
T2 | 233-242 | Body_part | denotes | pituitary | FMA:13889 |
T3 | 587-596 | Body_part | denotes | pituitary | FMA:13889 |
T4 | 1838-1847 | Body_part | denotes | pituitary | FMA:13889 |
T5 | 1873-1895 | Body_part | denotes | central nervous system | FMA:55675 |
T6 | 1939-1949 | Body_part | denotes | chromosome | FMA:67093 |
GlyCosmos15-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 40-49 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T2 | 233-242 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T3 | 587-596 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T4 | 1838-1847 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/MAT_0000077 |
T5 | 1873-1895 | Body_part | denotes | central nervous system | http://purl.obolibrary.org/obo/MAT_0000457 |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 460-466 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T2 | 641-647 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T3 | 673-678 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T4 | 697-702 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T5 | 708-714 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T6 | 746-751 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T7 | 766-777 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T8 | 819-830 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T9 | 1019-1025 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T10 | 1195-1200 | Glycan | denotes | HNK-1 | https://api.glycosmos.org/wurcs2image/latest/png/binary/G54406UD |
T11 | 1252-1258 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T12 | 1324-1335 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T13 | 1364-1370 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T14 | 1466-1477 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T15 | 1508-1514 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T16 | 1607-1613 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T17 | 1615-1621 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T18 | 1761-1767 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
T19 | 1901-1907 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
NCBITAXON
Id | Subject | Object | Predicate | Lexical cue | db_id |
---|---|---|---|---|---|
T1 | 1933-1938 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 40-49 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T2 | 233-242 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T3 | 587-596 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T4 | 890-903 | Body_part | denotes | transmembrane | http://purl.obolibrary.org/obo/GO_0016020 |
T5 | 993-1001 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
T8 | 1229-1237 | Body_part | denotes | membrane | http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158 |
T11 | 1838-1847 | Body_part | denotes | pituitary | http://purl.obolibrary.org/obo/UBERON_0000007 |
T12 | 1873-1895 | Body_part | denotes | central nervous system | http://purl.obolibrary.org/obo/UBERON_0001017 |
T13 | 1939-1949 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |