PubMed:10960795 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10960795","sourcedb":"PubMed","sourceid":"10960795","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10960795","text":"Developmental expression of the Xenopus Nkx2-1 and Nkx2-4 genes.\nThe homeodomain transcription factor Nkx2-1 (TTF-1) plays an essential role in the development of the thyroid, lung and ventral forebrain. We report the cloning and developmental expression patterns of two Xenopus NK-2 genes, Nkx2-1 and Nkx2-4, that are closely related to Nkx2-1. These genes show readily distinguishable expression patterns during development. Similar to its orthologues in chicken and mouse, the Xenopus Nkx2-1 gene is expressed in the developing thyroid, lung, and ventral forebrain. In contrast, expression of Nkx2-4 is specifically localized to the ventral diencephalon.","tracks":[]}