PubMed:10950950
Annnotations
CL-cell
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 506-511 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
T2 | 688-693 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
T3 | 968-973 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
GlyCosmos6-Glycan-Motif-Image
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 19-30 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T2 | 143-154 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T3 | 330-341 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T4 | 661-672 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T5 | 674-676 | Glycan_Motif | denotes | CH | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
T6 | 729-744 | Glycan_Motif | denotes | keratan sulfate | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G82109MW |
T7 | 1053-1055 | Glycan_Motif | denotes | CH | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-116 | Sentence | denotes | Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44. |
T2 | 117-278 | Sentence | denotes | Here we show that a large chondroitin sulfate proteoglycan, versican, derived from a renal adenocarcinoma cell line ACHN, binds L-selectin, P-selectin, and CD44. |
T3 | 279-440 | Sentence | denotes | The binding was mediated by the interaction of the chondroitin sulfate (CS) chain of versican with the carbohydrate-binding domain of L- and P-selectin and CD44. |
T4 | 441-587 | Sentence | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS) but not by any other glycosaminoglycans tested. |
T5 | 588-745 | Sentence | denotes | On the other hand, the binding to CD44 was inhibited by hyaluronic acid, chondroitin (CH), CS A, CS B, CS C, CS D, and CS E but not by HS or keratan sulfate. |
T6 | 746-891 | Sentence | denotes | A cross-blocking study indicated that L- and P-selectin recognize close or overlapping sites on versican, whereas CD44 recognizes separate sites. |
T7 | 892-1088 | Sentence | denotes | We also show that soluble L- and P-selectin directly bind to immobilized CS B, CS E, and HS and that soluble CD44 directly binds to immobilized hyaluronic acid, CH, and all the CS chains examined. |
T8 | 1089-1201 | Sentence | denotes | Consistent with these results, structural analysis showed that versican is modified with at least CS B and CS C. |
T9 | 1202-1343 | Sentence | denotes | Thus, proteoglycans sufficiently modified with the appropriate glycosaminoglycans should be able to bind L-selectin, P-selectin, and/or CD44. |
GlyCosmos6-Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 19-30 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T2 | 143-154 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T3 | 330-341 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T4 | 661-672 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
T5 | 729-744 | https://glytoucan.org/Structures/Glycans/G82109MW | denotes | keratan sulfate |
Glycosmos6-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 19-30 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T2 | 143-154 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T3 | 330-341 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T4 | 519-534 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | heparan sulfate |
T5 | 536-538 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
T6 | 661-672 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
T7 | 674-676 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | CH |
T8 | 723-725 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
T9 | 729-744 | http://www.glycoepitope.jp/epitopes/EP0085 | denotes | keratan sulfate |
T10 | 981-983 | http://www.glycoepitope.jp/epitopes/EP0086 | denotes | HS |
T11 | 1053-1055 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | CH |
Glycosmos6-MAT
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 601-605 | http://purl.obolibrary.org/obo/MAT_0000091 | denotes | hand |
2015-BEL-Sample-2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
BEL:20023822 | 441-538 | a(CHEBI:"dermatan sulfate") decreases complex(p(HGNC:VCAN),p(HGNC:SELL)) | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS |
BEL:20023824 | 441-538 | a(CHEBI:"dermatan sulfate") decreases complex(p(HGNC:VCAN),p(HGNC:SELP)) | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS |
Anatomy-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 601-605 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/MAT_0000091 |
mondo_disease
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 39-68 | Disease | denotes | dermatan sulfate proteoglycan | http://purl.obolibrary.org/obo/MONDO_0007526|http://purl.obolibrary.org/obo/MONDO_0020682 |
T3 | 202-222 | Disease | denotes | renal adenocarcinoma | http://purl.obolibrary.org/obo/MONDO_0017884 |
T4 | 503-507 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T5 | 679-683 | Disease | denotes | CS A | http://purl.obolibrary.org/obo/MONDO_0019569 |
T6 | 685-689 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T7 | 691-695 | Disease | denotes | CS C | http://purl.obolibrary.org/obo/MONDO_0018616 |
T8 | 965-969 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T9 | 1187-1191 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T10 | 1196-1200 | Disease | denotes | CS C | http://purl.obolibrary.org/obo/MONDO_0018616 |
Glycan-GlyCosmos
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 19-30 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T2 | 143-154 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T3 | 330-341 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T4 | 661-672 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T5 | 674-676 | Glycan | denotes | CH | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T6 | 729-744 | Glycan | denotes | keratan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW |
T7 | 1053-1055 | Glycan | denotes | CH | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T15 | 519-534 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T16 | 536-538 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T8 | 723-725 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T10 | 981-983 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
GlyCosmos-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 19-30 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T2 | 143-154 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T3 | 330-341 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T4 | 519-534 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
T5 | 536-538 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T6 | 661-672 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T7 | 674-676 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | CH | http://www.glycoepitope.jp/epitopes/EP0081 |
T8 | 723-725 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T9 | 729-744 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | keratan sulfate | http://www.glycoepitope.jp/epitopes/EP0085 |
T10 | 981-983 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T11 | 1053-1055 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | CH | http://www.glycoepitope.jp/epitopes/EP0081 |
GlyCosmos15-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T1 | 39-68 | Disease | denotes | dermatan sulfate proteoglycan | http://purl.obolibrary.org/obo/MONDO_0007526|http://purl.obolibrary.org/obo/MONDO_0020682 |
T3 | 202-222 | Disease | denotes | renal adenocarcinoma | http://purl.obolibrary.org/obo/MONDO_0017884 |
T4 | 503-507 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T5 | 679-683 | Disease | denotes | CS A | http://purl.obolibrary.org/obo/MONDO_0019569 |
T6 | 685-689 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T7 | 691-695 | Disease | denotes | CS C | http://purl.obolibrary.org/obo/MONDO_0018616 |
T8 | 965-969 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T9 | 1187-1191 | Disease | denotes | CS B | http://purl.obolibrary.org/obo/MONDO_0019570 |
T10 | 1196-1200 | Disease | denotes | CS C | http://purl.obolibrary.org/obo/MONDO_0018616 |
GlyCosmos15-CL
Id | Subject | Object | Predicate | Lexical cue | cl_id |
---|---|---|---|---|---|
T1 | 506-511 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
T2 | 688-693 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
T3 | 968-973 | Cell | denotes | B, CS | http://purl.obolibrary.org/obo/CL:0000748 |
GlyCosmos15-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 601-605 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |
GlyCosmos15-MAT
Id | Subject | Object | Predicate | Lexical cue | mat_id |
---|---|---|---|---|---|
T1 | 601-605 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/MAT_0000091 |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-116 | Sentence | denotes | Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44. |
T2 | 117-278 | Sentence | denotes | Here we show that a large chondroitin sulfate proteoglycan, versican, derived from a renal adenocarcinoma cell line ACHN, binds L-selectin, P-selectin, and CD44. |
T3 | 279-440 | Sentence | denotes | The binding was mediated by the interaction of the chondroitin sulfate (CS) chain of versican with the carbohydrate-binding domain of L- and P-selectin and CD44. |
T4 | 441-587 | Sentence | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS) but not by any other glycosaminoglycans tested. |
T5 | 588-745 | Sentence | denotes | On the other hand, the binding to CD44 was inhibited by hyaluronic acid, chondroitin (CH), CS A, CS B, CS C, CS D, and CS E but not by HS or keratan sulfate. |
T6 | 746-891 | Sentence | denotes | A cross-blocking study indicated that L- and P-selectin recognize close or overlapping sites on versican, whereas CD44 recognizes separate sites. |
T7 | 892-1088 | Sentence | denotes | We also show that soluble L- and P-selectin directly bind to immobilized CS B, CS E, and HS and that soluble CD44 directly binds to immobilized hyaluronic acid, CH, and all the CS chains examined. |
T8 | 1089-1201 | Sentence | denotes | Consistent with these results, structural analysis showed that versican is modified with at least CS B and CS C. |
T9 | 1202-1343 | Sentence | denotes | Thus, proteoglycans sufficiently modified with the appropriate glycosaminoglycans should be able to bind L-selectin, P-selectin, and/or CD44. |
GlyCosmos15-Sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-116 | Sentence | denotes | Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44. |
T2 | 117-278 | Sentence | denotes | Here we show that a large chondroitin sulfate proteoglycan, versican, derived from a renal adenocarcinoma cell line ACHN, binds L-selectin, P-selectin, and CD44. |
T3 | 279-440 | Sentence | denotes | The binding was mediated by the interaction of the chondroitin sulfate (CS) chain of versican with the carbohydrate-binding domain of L- and P-selectin and CD44. |
T4 | 441-587 | Sentence | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS) but not by any other glycosaminoglycans tested. |
T5 | 588-745 | Sentence | denotes | On the other hand, the binding to CD44 was inhibited by hyaluronic acid, chondroitin (CH), CS A, CS B, CS C, CS D, and CS E but not by HS or keratan sulfate. |
T6 | 746-891 | Sentence | denotes | A cross-blocking study indicated that L- and P-selectin recognize close or overlapping sites on versican, whereas CD44 recognizes separate sites. |
T7 | 892-1088 | Sentence | denotes | We also show that soluble L- and P-selectin directly bind to immobilized CS B, CS E, and HS and that soluble CD44 directly binds to immobilized hyaluronic acid, CH, and all the CS chains examined. |
T8 | 1089-1343 | Sentence | denotes | Consistent with these results, structural analysis showed that versican is modified with at least CS B and CS C. Thus, proteoglycans sufficiently modified with the appropriate glycosaminoglycans should be able to bind L-selectin, P-selectin, and/or CD44. |
GlyCosmos15-Glycan
Id | Subject | Object | Predicate | Lexical cue | image |
---|---|---|---|---|---|
T1 | 19-30 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T2 | 143-154 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T3 | 330-341 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T4 | 661-672 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T5 | 674-676 | Glycan | denotes | CH | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T6 | 729-744 | Glycan | denotes | keratan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G82109MW |
T7 | 1053-1055 | Glycan | denotes | CH | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
T15 | 519-534 | Glycan | denotes | heparan sulfate | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T16 | 536-538 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T8 | 723-725 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
T10 | 981-983 | Glycan | denotes | HS | https://api.glycosmos.org/wurcs2image/latest/png/binary/G17927IW |
GlyCosmos15-GlycoEpitope
Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
---|---|---|---|---|---|
T1 | 19-30 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T2 | 143-154 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T3 | 330-341 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T4 | 519-534 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | heparan sulfate | http://www.glycoepitope.jp/epitopes/EP0086 |
T5 | 536-538 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T6 | 661-672 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
T7 | 674-676 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | CH | http://www.glycoepitope.jp/epitopes/EP0081 |
T8 | 723-725 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T9 | 729-744 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | keratan sulfate | http://www.glycoepitope.jp/epitopes/EP0085 |
T10 | 981-983 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | HS | http://www.glycoepitope.jp/epitopes/EP0086 |
T11 | 1053-1055 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | CH | http://www.glycoepitope.jp/epitopes/EP0081 |
Lectin-Jamboree-Sentence
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-116 | Sentence | denotes | Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44. |
T2 | 117-278 | Sentence | denotes | Here we show that a large chondroitin sulfate proteoglycan, versican, derived from a renal adenocarcinoma cell line ACHN, binds L-selectin, P-selectin, and CD44. |
T3 | 279-440 | Sentence | denotes | The binding was mediated by the interaction of the chondroitin sulfate (CS) chain of versican with the carbohydrate-binding domain of L- and P-selectin and CD44. |
T4 | 441-587 | Sentence | denotes | The binding of versican to L- and P-selectin was inhibited by CS B, CS E, and heparan sulfate (HS) but not by any other glycosaminoglycans tested. |
T5 | 588-745 | Sentence | denotes | On the other hand, the binding to CD44 was inhibited by hyaluronic acid, chondroitin (CH), CS A, CS B, CS C, CS D, and CS E but not by HS or keratan sulfate. |
T6 | 746-891 | Sentence | denotes | A cross-blocking study indicated that L- and P-selectin recognize close or overlapping sites on versican, whereas CD44 recognizes separate sites. |
T7 | 892-1088 | Sentence | denotes | We also show that soluble L- and P-selectin directly bind to immobilized CS B, CS E, and HS and that soluble CD44 directly binds to immobilized hyaluronic acid, CH, and all the CS chains examined. |
T8 | 1089-1343 | Sentence | denotes | Consistent with these results, structural analysis showed that versican is modified with at least CS B and CS C. Thus, proteoglycans sufficiently modified with the appropriate glycosaminoglycans should be able to bind L-selectin, P-selectin, and/or CD44. |
Anatomy-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T1 | 601-605 | Body_part | denotes | hand | http://purl.obolibrary.org/obo/UBERON_0002398 |