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PubMed:10946794 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-116 Sentence denotes Interactions of perturbations in intrauterine growth and growth during childhood on the risk of adult-onset disease.
TextSentencer_T2 117-293 Sentence denotes The 'fetal origins' hypothesis (Barker, 1995) would predict that the rising epidemic of diabetes and CHD in India would be due to poor intrauterine growth of the Indian babies.
TextSentencer_T3 294-507 Sentence denotes While this explanation may be valid to an extent, the higher prevalence of these disorders in urban compared with rural India (where birth weights are lower) would suggest a significant role for postnatal factors.
TextSentencer_T4 508-671 Sentence denotes In a cohort of 477 children born in the King Edward Memorial Hospital, Pune, we found that at 8 years of age current obesity strongly predicted insulin resistance.
TextSentencer_T5 672-824 Sentence denotes When this effect was allowed for, low birth weight was significantly associated with insulin-resistance variables and other cardiovascular risk factors.
TextSentencer_T6 825-974 Sentence denotes Children who were born small but had grown heavy (or tall) were the most insulin resistant and had the highest levels of cardiovascular risk factors.
TextSentencer_T7 975-1054 Sentence denotes Accelerated growth in relation to mid parental height was similarly predictive.
TextSentencer_T8 1055-1138 Sentence denotes Poor intrauterine growth also predicted higher central adiposity at 8 years of age.
TextSentencer_T9 1139-1222 Sentence denotes We have also studied maternal nutrition and fetal growth in six villages near Pune.
TextSentencer_T10 1223-1476 Sentence denotes A newborn Indian baby is small (2650 g, SD score (SDS) -1.6 compared with an average white Caucasian baby born in the UK) and 'thin' (ponderal index 2.45 kg/m3, SDS -1.2), but has preserved its subcutaneous fat (subscapular skinfold thickness SDS -0.6).
TextSentencer_T11 1477-1561 Sentence denotes The thinness of the Indian babies is due to poor muscle and small abdominal viscera.
TextSentencer_T12 1562-1663 Sentence denotes We have proposed this composition as the 'thrifty phenotype' (Hales & Barker, 1992) of Indian babies.
TextSentencer_T13 1664-1781 Sentence denotes Maternal size and intake of certain food groups during pregnancy were important determinants of the baby's phenotype.
TextSentencer_T14 1782-1871 Sentence denotes Thus, the small Indian babies are programmed to deposit fat from their intrauterine life.
TextSentencer_T15 1872-1963 Sentence denotes Exaggeration of this tendency in later life is associated with insulin-resistance syndrome.
TextSentencer_T16 1964-2102 Sentence denotes Control of the insulin-resistance epidemic in India might depend on improved intrauterine development and prevention of childhood obesity.
T1 0-116 Sentence denotes Interactions of perturbations in intrauterine growth and growth during childhood on the risk of adult-onset disease.
T2 117-293 Sentence denotes The 'fetal origins' hypothesis (Barker, 1995) would predict that the rising epidemic of diabetes and CHD in India would be due to poor intrauterine growth of the Indian babies.
T3 294-507 Sentence denotes While this explanation may be valid to an extent, the higher prevalence of these disorders in urban compared with rural India (where birth weights are lower) would suggest a significant role for postnatal factors.
T4 508-671 Sentence denotes In a cohort of 477 children born in the King Edward Memorial Hospital, Pune, we found that at 8 years of age current obesity strongly predicted insulin resistance.
T5 672-824 Sentence denotes When this effect was allowed for, low birth weight was significantly associated with insulin-resistance variables and other cardiovascular risk factors.
T6 825-974 Sentence denotes Children who were born small but had grown heavy (or tall) were the most insulin resistant and had the highest levels of cardiovascular risk factors.
T7 975-1054 Sentence denotes Accelerated growth in relation to mid parental height was similarly predictive.
T8 1055-1138 Sentence denotes Poor intrauterine growth also predicted higher central adiposity at 8 years of age.
T9 1139-1222 Sentence denotes We have also studied maternal nutrition and fetal growth in six villages near Pune.
T10 1223-1476 Sentence denotes A newborn Indian baby is small (2650 g, SD score (SDS) -1.6 compared with an average white Caucasian baby born in the UK) and 'thin' (ponderal index 2.45 kg/m3, SDS -1.2), but has preserved its subcutaneous fat (subscapular skinfold thickness SDS -0.6).
T11 1477-1561 Sentence denotes The thinness of the Indian babies is due to poor muscle and small abdominal viscera.
T12 1562-1663 Sentence denotes We have proposed this composition as the 'thrifty phenotype' (Hales & Barker, 1992) of Indian babies.
T13 1664-1781 Sentence denotes Maternal size and intake of certain food groups during pregnancy were important determinants of the baby's phenotype.
T14 1782-1871 Sentence denotes Thus, the small Indian babies are programmed to deposit fat from their intrauterine life.
T15 1872-1963 Sentence denotes Exaggeration of this tendency in later life is associated with insulin-resistance syndrome.
T16 1964-2102 Sentence denotes Control of the insulin-resistance epidemic in India might depend on improved intrauterine development and prevention of childhood obesity.

performance-test

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1102-1109 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
PD-UBERON-AE-B_T2 1543-1560 http://purl.obolibrary.org/obo/UBERON_0017672 denotes abdominal viscera

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 625-632 HP_0001513 denotes obesity
T2 652-670 HP_0000855 denotes insulin resistance
T3 706-722 HP_0001518 denotes low birth weight
T4 757-775 HP_0000855 denotes insulin-resistance
T5 898-915 HP_0000855 denotes insulin resistant
T6 1935-1953 HP_0000855 denotes insulin-resistance
T7 1979-1997 HP_0000855 denotes insulin-resistance
T8 2094-2101 HP_0001513 denotes obesity

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
10946794-1#101#104#gene55349 218-221 gene55349 denotes CHD
10946794-1#88#96#diseaseC0011847 205-213 diseaseC0011847 denotes diabetes
10946794-1#88#96#diseaseC0011849 205-213 diseaseC0011849 denotes diabetes
101#104#gene5534988#96#diseaseC0011847 10946794-1#101#104#gene55349 10946794-1#88#96#diseaseC0011847 associated_with CHD,diabetes
101#104#gene5534988#96#diseaseC0011849 10946794-1#101#104#gene55349 10946794-1#88#96#diseaseC0011849 associated_with CHD,diabetes

DisGeNet-2017-sample

Id Subject Object Predicate Lexical cue
T2666 218-221 gene:55349 denotes CHD
T2667 205-213 disease:C0011847 denotes diabetes
R1 T2666 T2667 associated_with CHD,diabetes
R2 T2666 T2667 associated_with CHD,diabetes

UBERON-AE

Id Subject Object Predicate Lexical cue
PD-UBERON-AE-B_T1 1102-1109 http://purl.obolibrary.org/obo/UBERON_0012131 denotes central
PD-UBERON-AE-B_T2 1543-1560 http://purl.obolibrary.org/obo/UBERON_0017672 denotes abdominal viscera

DisGeNET

Id Subject Object Predicate Lexical cue
T0 1979-1986 gene:723961 denotes insulin
T1 2084-2101 disease:C2362324 denotes childhood obesity
T2 1979-1986 gene:723961 denotes insulin
T3 2084-2101 disease:C3645710 denotes childhood obesity
T4 1979-1986 gene:3630 denotes insulin
T5 2084-2101 disease:C2362324 denotes childhood obesity
T6 1979-1986 gene:3630 denotes insulin
T7 2084-2101 disease:C3645710 denotes childhood obesity
R1 T0 T1 associated_with insulin,childhood obesity
R2 T2 T3 associated_with insulin,childhood obesity
R3 T4 T5 associated_with insulin,childhood obesity
R4 T6 T7 associated_with insulin,childhood obesity