> top > docs > PubMed:10938284 > annotations

PubMed:10938284 JSONTXT

Annnotations TAB JSON ListView MergeView

sentences

Id Subject Object Predicate Lexical cue
T1 0-175 Sentence denotes The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity.
T2 176-261 Sentence denotes Rat synaptotagmin IV (SYT IV) is a depolarization-inducible synaptic vesicle protein.
T3 262-373 Sentence denotes SYT IV homozygous mutant mice are viable and have deficits in fine motor coordination and some forms of memory.
T4 374-447 Sentence denotes In this study, we report the identification of a human SYT IV orthologue.
T5 448-569 Sentence denotes The predicted amino acid sequence of the human SYT IV clone is nearly 90% identical to the rat and mouse SYT IV proteins.
T6 570-770 Sentence denotes In addition, human SYT IV has a characteristic serine for aspartate substitution within the first C2 domain that is conserved among Drosophila, Caenorhabditis elegans, mouse, and rat SYT IV sequences.
T7 771-983 Sentence denotes The human SYT IV gene maps to chromosome band 18q12.3, a region that defines a break point in the synteny with mouse chromosome 18 and has been implicated by associated markers in two human psychiatric disorders.
T8 984-1159 Sentence denotes In the human neuroblastoma cell line SK-N-SH, SYT IV is an immediate-early gene inducible by elevated intracellular calcium and by forskolin, an activator of adenylyl cyclase.
T9 1160-1261 Sentence denotes Expression of human SYT IV mRNA is restricted to brain and is not detectable in non-neuronal tissues.
T10 1262-1386 Sentence denotes Within brain, human SYT IV mRNA is most highly expressed in hippocampus, with lower levels present in amygdala and thalamus.
T11 1387-1485 Sentence denotes These results suggest a role for SYT IV in human brain function and in human neurological disease.

Glycosmos6-MAT

Id Subject Object Predicate Lexical cue
T1 1209-1214 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T2 1269-1274 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain
T3 1322-1333 http://purl.obolibrary.org/obo/MAT_0000114 denotes hippocampus
T4 1364-1372 http://purl.obolibrary.org/obo/MAT_0000289 denotes amygdala
T5 1377-1385 http://purl.obolibrary.org/obo/MAT_0000109 denotes thalamus
T6 1436-1441 http://purl.obolibrary.org/obo/MAT_0000098 denotes brain

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 961-982 HP_0000708 denotes psychiatric disorders
T2 997-1010 HP_0003006 denotes neuroblastoma

PennBioIE

Id Subject Object Predicate Lexical cue
T1 10-26 protein denotes synaptotagmin IV
T2 184-196 protein denotes ptotagmin IV
T3 198-204 protein denotes SYT IV
T4 262-268 protein denotes SYT IV
T5 429-435 protein denotes SYT IV
T6 495-501 protein denotes SYT IV
T7 553-559 protein denotes SYT IV
T8 589-595 protein denotes SYT IV
T9 617-623 protein denotes serine
T10 628-637 protein denotes aspartate
T11 638-650 protein denotes substitution
T12 662-677 protein denotes first C2 domain
T13 753-759 protein denotes SYT IV
T14 781-787 protein denotes SYT IV
T15 801-824 protein denotes chromosome band 18q12.3
T16 888-901 protein denotes chromosome 18
T17 997-1010 protein denotes neuroblastoma
T18 1030-1036 protein denotes SYT IV
T19 1142-1158 protein denotes adenylyl cyclase
T20 1180-1186 protein denotes SYT IV
T21 1282-1288 protein denotes SYT IV
T22 1420-1426 protein denotes SYT IV

DisGeNET5_gene_disease

Id Subject Object Predicate Lexical cue
10938284-6#10#16#gene6860 781-787 gene6860 denotes SYT IV
10938284-6#190#211#diseaseC0004936 961-982 diseaseC0004936 denotes psychiatric disorders
10938284-6#190#211#diseaseC0233514 961-982 diseaseC0233514 denotes psychiatric disorders
10#16#gene6860190#211#diseaseC0004936 10938284-6#10#16#gene6860 10938284-6#190#211#diseaseC0004936 associated_with SYT IV,psychiatric disorders
10#16#gene6860190#211#diseaseC0233514 10938284-6#10#16#gene6860 10938284-6#190#211#diseaseC0233514 associated_with SYT IV,psychiatric disorders

DisGeNET

Id Subject Object Predicate Lexical cue
T0 781-787 gene:6860 denotes SYT IV
T1 961-982 disease:C0004936 denotes psychiatric disorders
R1 T0 T1 associated_with SYT IV,psychiatric disorders

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 961-982 Disease denotes psychiatric disorders http://purl.obolibrary.org/obo/MONDO_0002025
T2 997-1010 Disease denotes neuroblastoma http://purl.obolibrary.org/obo/MONDO_0005072
T3 1464-1484 Disease denotes neurological disease http://purl.obolibrary.org/obo/MONDO_0005071

HP-phenotype

Id Subject Object Predicate Lexical cue hp_id
T1 961-982 Phenotype denotes psychiatric disorders HP:0000708
T2 997-1010 Phenotype denotes neuroblastoma HP:0003006

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 4-9 OrganismTaxon denotes human 9606
T2 85-90 OrganismTaxon denotes mouse 10088|10090
T4 95-100 OrganismTaxon denotes human 9606
T5 287-291 OrganismTaxon denotes mice 10088
T6 423-428 OrganismTaxon denotes human 9606
T7 489-494 OrganismTaxon denotes human 9606
T8 539-542 OrganismTaxon denotes rat 10114|10116
T10 547-552 OrganismTaxon denotes mouse 10088|10090
T12 583-588 OrganismTaxon denotes human 9606
T13 702-712 OrganismTaxon denotes Drosophila 2081351|32281|7215
T16 714-736 OrganismTaxon denotes Caenorhabditis elegans 6239
T17 738-743 OrganismTaxon denotes mouse 10088|10090
T19 749-752 OrganismTaxon denotes rat 10114|10116
T21 775-780 OrganismTaxon denotes human 9606
T22 882-887 OrganismTaxon denotes mouse 10088|10090
T24 955-960 OrganismTaxon denotes human 9606
T25 991-996 OrganismTaxon denotes human 9606
T26 1174-1179 OrganismTaxon denotes human 9606
T27 1276-1281 OrganismTaxon denotes human 9606
T28 1322-1333 OrganismTaxon denotes hippocampus 72046
T29 1430-1435 OrganismTaxon denotes human 9606
T30 1458-1463 OrganismTaxon denotes human 9606

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 101-111 Body_part denotes chromosome http://purl.obolibrary.org/obo/GO_0005694
T2 156-162 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479
T3 245-252 Body_part denotes vesicle http://purl.obolibrary.org/obo/GO_0031982
T4 801-811 Body_part denotes chromosome http://purl.obolibrary.org/obo/GO_0005694
T5 888-898 Body_part denotes chromosome http://purl.obolibrary.org/obo/GO_0005694
T6 1086-1099 Body_part denotes intracellular http://purl.obolibrary.org/obo/GO_0005622
T7 1209-1214 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T9 1269-1274 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636
T11 1322-1333 Body_part denotes hippocampus http://purl.obolibrary.org/obo/UBERON_0001954|http://purl.obolibrary.org/obo/UBERON_0002421|http://purl.obolibrary.org/obo/UBERON_0002961
T14 1364-1372 Body_part denotes amygdala http://purl.obolibrary.org/obo/UBERON_0001876
T15 1377-1385 Body_part denotes thalamus http://purl.obolibrary.org/obo/UBERON_0001897
T16 1436-1441 Body_part denotes brain http://purl.obolibrary.org/obo/UBERON_0000955|http://purl.obolibrary.org/obo/UBERON_6110636

Anatomy-MAT

Id Subject Object Predicate Lexical cue mat_id
T1 1209-1214 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T2 1269-1274 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098
T3 1322-1333 Body_part denotes hippocampus http://purl.obolibrary.org/obo/MAT_0000114
T4 1364-1372 Body_part denotes amygdala http://purl.obolibrary.org/obo/MAT_0000289
T5 1377-1385 Body_part denotes thalamus http://purl.obolibrary.org/obo/MAT_0000109
T6 1436-1441 Body_part denotes brain http://purl.obolibrary.org/obo/MAT_0000098

CL-cell

Id Subject Object Predicate Lexical cue cl_id
T1 812-816 Cell denotes band http://purl.obolibrary.org/obo/CL:0000560
T2 1244-1252 Cell denotes neuronal http://purl.obolibrary.org/obo/CL:0000540