PubMed:10896779 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10896779","sourcedb":"PubMed","sourceid":"10896779","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10896779","text":"In vivo migration of transplanted myoblasts requires matrix metalloproteinase activity.\nMuscle cell migration and extracellular matrix remodeling are essential aspects of muscle development and regeneration. In this study, using a new technique to assess in vivo myoblast migration, we have confirmed previous results showing that the C(2)C(12) myoblast cell line exhibits a higher migratory capacity than primary myoblasts. To test the hypothesis that matrix metalloproteinases (MMPs) are required for the migration of C(2)C(12) myoblasts, we determined whether a synthetic metalloproteinase inhibitor, BB94 (Batimastat), inhibited this process in vivo. Pretreatment with BB94 for 3 days decreased the C(2)C(12) migration at 2 days after cell injection. Since MMP expression is thus necessary for myoblast migration, we have undertaken the identification and characterization of the MMPs expressed by the C(2)C(12) cell line. An RT-PCR assay was used to determine the pattern of MMP mRNA expression by the C(2)C(12) cell line. The proteolytic activities of the MMPs secreted in the culture medium were also assessed by gelatin zymography. The results showed that MMP2 (gelatinase A, 72-kDa type IV collagenase) and MT1-MMP transcripts were expressed by this cell line; however, only MMP2 was secreted and was able to be activated in the extracellular environment. This cell line failed to express MMP9 (gelatinase B, 92-kDa type IV collagenase), stromelysine 2, or stromelysine 3. Our observation that the membrane type MMP (MT1-MMP) transcript is also expressed by the C(2)C(12) suggests that the MMP2 proform (pro-MMP2), may be activated by the MT1-MMP. This possibility is supported by our observation that the pretreatment of C(2)C(12) with concanavalin A (which is known to induce the expression of MT1-MMP) resulted in the processing of pro-MMP2 to its mature form, in a dose-dependent manner. Overexpression and activation of MMP2 in normal myoblasts showed significant increased migration of mouse myoblasts in vivo. Our finding that MMP2 and MT1-MMP gene are coexpressed by C(2)C(12) myoblasts could account for the high migratory capacity of C(2)C(12). Together these results supported the importance of MMP2 and its activation by MT1-MMP for myoblast migration.","tracks":[{"project":"c_corpus","denotations":[{"id":"T1","span":{"begin":53,"end":59},"obj":"UBERON:0027368"},{"id":"T2","span":{"begin":60,"end":86},"obj":"GO:0008237"},{"id":"T3","span":{"begin":95,"end":109},"obj":"GO:0016477"},{"id":"T5","span":{"begin":114,"end":134},"obj":"GO:0031012"},{"id":"T6","span":{"begin":128,"end":134},"obj":"UBERON:0027368"},{"id":"T7","span":{"begin":171,"end":177},"obj":"UBERON:0001630"},{"id":"T8","span":{"begin":171,"end":177},"obj":"UBERON:0005090"},{"id":"T9","span":{"begin":194,"end":206},"obj":"GO:0031099"},{"id":"T10","span":{"begin":263,"end":271},"obj":"CL:0000056"},{"id":"T11","span":{"begin":263,"end":281},"obj":"GO:0051451"},{"id":"T12","span":{"begin":335,"end":343},"obj":"CVCL_0188"},{"id":"T13","span":{"begin":339,"end":343},"obj":"P51525"},{"id":"T16","span":{"begin":339,"end":343},"obj":"CHEBI:87146"},{"id":"T18","span":{"begin":345,"end":353},"obj":"CL:0000056"},{"id":"T19","span":{"begin":453,"end":459},"obj":"UBERON:0027368"},{"id":"T20","span":{"begin":453,"end":478},"obj":"D020782"},{"id":"T22","span":{"begin":480,"end":484},"obj":"D020782"},{"id":"T23","span":{"begin":520,"end":528},"obj":"CVCL_0188"},{"id":"T24","span":{"begin":524,"end":528},"obj":"P51525"},{"id":"T27","span":{"begin":524,"end":528},"obj":"CHEBI:87146"},{"id":"T29","span":{"begin":565,"end":574},"obj":"32630"},{"id":"T30","span":{"begin":565,"end":602},"obj":"C075190"},{"id":"T31","span":{"begin":565,"end":602},"obj":"C075190"},{"id":"T33","span":{"begin":575,"end":602},"obj":"P29695"},{"id":"T34","span":{"begin":575,"end":602},"obj":"P01077"},{"id":"T35","span":{"begin":575,"end":602},"obj":"Q9DGI0"},{"id":"T32","span":{"begin":575,"end":602},"obj":"GO:0008191"},{"id":"T37","span":{"begin":604,"end":608},"obj":"C080985"},{"id":"T38","span":{"begin":604,"end":608},"obj":"C080985"},{"id":"T39","span":{"begin":610,"end":620},"obj":"C080985"},{"id":"T40","span":{"begin":610,"end":620},"obj":"C080985"},{"id":"T41","span":{"begin":673,"end":677},"obj":"C080985"},{"id":"T42","span":{"begin":673,"end":677},"obj":"C080985"},{"id":"T45","span":{"begin":703,"end":711},"obj":"CVCL_0188"},{"id":"T46","span":{"begin":707,"end":711},"obj":"P51525"},{"id":"T49","span":{"begin":707,"end":711},"obj":"CHEBI:87146"},{"id":"T68","span":{"begin":761,"end":764},"obj":"PR:O04529"},{"id":"T66","span":{"begin":761,"end":764},"obj":"CHEBI:340824"},{"id":"T69","span":{"begin":761,"end":764},"obj":"CHEBI:59761"},{"id":"T67","span":{"begin":761,"end":764},"obj":"GO:0004235"},{"id":"T70","span":{"begin":798,"end":806},"obj":"CL:0000056"},{"id":"T71","span":{"begin":798,"end":816},"obj":"GO:0051451"},{"id":"T72","span":{"begin":884,"end":888},"obj":"D020782"},{"id":"T73","span":{"begin":906,"end":914},"obj":"CVCL_0188"},{"id":"T74","span":{"begin":910,"end":914},"obj":"P51525"},{"id":"T77","span":{"begin":910,"end":914},"obj":"CHEBI:87146"},{"id":"T79","span":{"begin":933,"end":936},"obj":"Q41249"},{"id":"T80","span":{"begin":933,"end":936},"obj":"O66148"},{"id":"T81","span":{"begin":933,"end":936},"obj":"Q59987"},{"id":"T82","span":{"begin":933,"end":936},"obj":"Q01289"},{"id":"T83","span":{"begin":933,"end":936},"obj":"O80333"},{"id":"T84","span":{"begin":933,"end":936},"obj":"P15904"},{"id":"T85","span":{"begin":933,"end":936},"obj":"Q9SDT1"},{"id":"T86","span":{"begin":933,"end":936},"obj":"Q39617"},{"id":"T89","span":{"begin":980,"end":983},"obj":"PR:O04529"},{"id":"T87","span":{"begin":980,"end":983},"obj":"CHEBI:340824"},{"id":"T90","span":{"begin":980,"end":983},"obj":"CHEBI:59761"},{"id":"T88","span":{"begin":980,"end":983},"obj":"GO:0004235"},{"id":"T93","span":{"begin":984,"end":988},"obj":"SO:0000234"},{"id":"T91","span":{"begin":984,"end":988},"obj":"D012333"},{"id":"T92","span":{"begin":984,"end":988},"obj":"CHEBI:33699"},{"id":"T94","span":{"begin":1007,"end":1015},"obj":"CVCL_0188"},{"id":"T95","span":{"begin":1011,"end":1015},"obj":"P51525"},{"id":"T98","span":{"begin":1011,"end":1015},"obj":"CHEBI:87146"},{"id":"T100","span":{"begin":1062,"end":1066},"obj":"D020782"},{"id":"T101","span":{"begin":1120,"end":1127},"obj":"4716"},{"id":"T102","span":{"begin":1120,"end":1127},"obj":"D005780"},{"id":"T103","span":{"begin":1120,"end":1127},"obj":"CHEBI:5291"},{"id":"T104","span":{"begin":1164,"end":1167},"obj":"CHEBI:340824"},{"id":"T107","span":{"begin":1164,"end":1167},"obj":"CHEBI:59761"},{"id":"T108","span":{"begin":1164,"end":1168},"obj":"PR:P08253"},{"id":"T109","span":{"begin":1164,"end":1168},"obj":"Q9GLE5"},{"id":"T110","span":{"begin":1164,"end":1168},"obj":"P08253"},{"id":"T111","span":{"begin":1164,"end":1168},"obj":"Q90611"},{"id":"T113","span":{"begin":1164,"end":1168},"obj":"PR:Q8MPP3"},{"id":"T114","span":{"begin":1164,"end":1168},"obj":"P33436"},{"id":"T115","span":{"begin":1164,"end":1168},"obj":"PR:Q90611"},{"id":"T116","span":{"begin":1164,"end":1168},"obj":"PR:P33436"},{"id":"T117","span":{"begin":1164,"end":1168},"obj":"PR:000010479"},{"id":"T118","span":{"begin":1164,"end":1168},"obj":"PR:P33434"},{"id":"T119","span":{"begin":1164,"end":1168},"obj":"P33434"},{"id":"T120","span":{"begin":1164,"end":1168},"obj":"P50757"},{"id":"T112","span":{"begin":1164,"end":1168},"obj":"GO:0004228"},{"id":"T123","span":{"begin":1170,"end":1182},"obj":"P08253"},{"id":"T124","span":{"begin":1170,"end":1182},"obj":"Q90611"},{"id":"T126","span":{"begin":1170,"end":1182},"obj":"PR:000010479"},{"id":"T127","span":{"begin":1170,"end":1182},"obj":"P33436"},{"id":"T128","span":{"begin":1170,"end":1182},"obj":"P33434"},{"id":"T129","span":{"begin":1170,"end":1182},"obj":"P50757"},{"id":"T125","span":{"begin":1170,"end":1182},"obj":"D020778"},{"id":"T130","span":{"begin":1181,"end":1186},"obj":"CVCL_3453"},{"id":"T131","span":{"begin":1184,"end":1210},"obj":"Q9GLE5"},{"id":"T132","span":{"begin":1184,"end":1210},"obj":"P08253"},{"id":"T133","span":{"begin":1184,"end":1210},"obj":"Q90611"},{"id":"T135","span":{"begin":1184,"end":1210},"obj":"PR:000010479"},{"id":"T136","span":{"begin":1184,"end":1210},"obj":"P33436"},{"id":"T137","span":{"begin":1184,"end":1210},"obj":"P33434"},{"id":"T138","span":{"begin":1184,"end":1210},"obj":"P50757"},{"id":"T134","span":{"begin":1184,"end":1210},"obj":"D020778"},{"id":"T140","span":{"begin":1199,"end":1210},"obj":"58939"},{"id":"T167","span":{"begin":1216,"end":1219},"obj":"CVCL_2501"},{"id":"T152","span":{"begin":1216,"end":1219},"obj":"GO:0047152"},{"id":"T161","span":{"begin":1216,"end":1219},"obj":"GO:0043791"},{"id":"T170","span":{"begin":1216,"end":1219},"obj":"GO:0043834"},{"id":"T186","span":{"begin":1216,"end":1223},"obj":"Q9XT90"},{"id":"T187","span":{"begin":1216,"end":1223},"obj":"P50281"},{"id":"T188","span":{"begin":1216,"end":1223},"obj":"Q9GLE4"},{"id":"T189","span":{"begin":1216,"end":1223},"obj":"PR:000010474"},{"id":"T190","span":{"begin":1216,"end":1223},"obj":"Q10739"},{"id":"T191","span":{"begin":1216,"end":1223},"obj":"Q95220"},{"id":"T193","span":{"begin":1216,"end":1223},"obj":"P53690"},{"id":"T192","span":{"begin":1216,"end":1223},"obj":"D053511"},{"id":"T196","span":{"begin":1220,"end":1223},"obj":"GO:0004235"},{"id":"T199","span":{"begin":1284,"end":1287},"obj":"CHEBI:340824"},{"id":"T202","span":{"begin":1284,"end":1287},"obj":"CHEBI:59761"},{"id":"T203","span":{"begin":1284,"end":1288},"obj":"PR:P08253"},{"id":"T204","span":{"begin":1284,"end":1288},"obj":"Q9GLE5"},{"id":"T205","span":{"begin":1284,"end":1288},"obj":"P08253"},{"id":"T206","span":{"begin":1284,"end":1288},"obj":"Q90611"},{"id":"T208","span":{"begin":1284,"end":1288},"obj":"PR:Q8MPP3"},{"id":"T209","span":{"begin":1284,"end":1288},"obj":"P33436"},{"id":"T210","span":{"begin":1284,"end":1288},"obj":"PR:Q90611"},{"id":"T211","span":{"begin":1284,"end":1288},"obj":"PR:P33436"},{"id":"T212","span":{"begin":1284,"end":1288},"obj":"PR:000010479"},{"id":"T213","span":{"begin":1284,"end":1288},"obj":"PR:P33434"},{"id":"T214","span":{"begin":1284,"end":1288},"obj":"P33434"},{"id":"T215","span":{"begin":1284,"end":1288},"obj":"P50757"},{"id":"T207","span":{"begin":1284,"end":1288},"obj":"GO:0004228"},{"id":"T216","span":{"begin":1338,"end":1351},"obj":"GO:0005576"},{"id":"T217","span":{"begin":1398,"end":1401},"obj":"CHEBI:340824"},{"id":"T220","span":{"begin":1398,"end":1401},"obj":"CHEBI:59761"},{"id":"T221","span":{"begin":1398,"end":1402},"obj":"PR:P50282"},{"id":"T222","span":{"begin":1398,"end":1402},"obj":"PR:P14780"},{"id":"T223","span":{"begin":1398,"end":1402},"obj":"P14780"},{"id":"T224","span":{"begin":1398,"end":1402},"obj":"PR:P41245"},{"id":"T225","span":{"begin":1398,"end":1402},"obj":"P41246"},{"id":"T226","span":{"begin":1398,"end":1402},"obj":"P41245"},{"id":"T227","span":{"begin":1398,"end":1402},"obj":"PR:P52176"},{"id":"T228","span":{"begin":1398,"end":1402},"obj":"P50282"},{"id":"T230","span":{"begin":1398,"end":1402},"obj":"PR:000010491"},{"id":"T231","span":{"begin":1398,"end":1402},"obj":"P52176"},{"id":"T232","span":{"begin":1398,"end":1402},"obj":"O18733"},{"id":"T229","span":{"begin":1398,"end":1402},"obj":"GO:0004229"},{"id":"T236","span":{"begin":1404,"end":1416},"obj":"P14780"},{"id":"T237","span":{"begin":1404,"end":1416},"obj":"P41246"},{"id":"T238","span":{"begin":1404,"end":1416},"obj":"P41245"},{"id":"T239","span":{"begin":1404,"end":1416},"obj":"P50282"},{"id":"T240","span":{"begin":1404,"end":1416},"obj":"PR:000010491"},{"id":"T241","span":{"begin":1404,"end":1416},"obj":"P52176"},{"id":"T242","span":{"begin":1404,"end":1416},"obj":"O18733"},{"id":"T235","span":{"begin":1404,"end":1416},"obj":"D020780"},{"id":"T243","span":{"begin":1415,"end":1420},"obj":"CVCL_4115"},{"id":"T245","span":{"begin":1418,"end":1444},"obj":"P14780"},{"id":"T246","span":{"begin":1418,"end":1444},"obj":"P41246"},{"id":"T247","span":{"begin":1418,"end":1444},"obj":"P41245"},{"id":"T248","span":{"begin":1418,"end":1444},"obj":"P50282"},{"id":"T249","span":{"begin":1418,"end":1444},"obj":"PR:000010491"},{"id":"T250","span":{"begin":1418,"end":1444},"obj":"P52176"},{"id":"T251","span":{"begin":1418,"end":1444},"obj":"O18733"},{"id":"T244","span":{"begin":1418,"end":1444},"obj":"D020780"},{"id":"T253","span":{"begin":1433,"end":1444},"obj":"58939"},{"id":"T259","span":{"begin":1507,"end":1515},"obj":"GO:0016020"},{"id":"T258","span":{"begin":1507,"end":1515},"obj":"UBERON:0000094"},{"id":"T260","span":{"begin":1507,"end":1515},"obj":"UBERON:0000158"},{"id":"T263","span":{"begin":1521,"end":1524},"obj":"PR:O04529"},{"id":"T261","span":{"begin":1521,"end":1524},"obj":"CHEBI:340824"},{"id":"T264","span":{"begin":1521,"end":1524},"obj":"CHEBI:59761"},{"id":"T262","span":{"begin":1521,"end":1524},"obj":"GO:0004235"},{"id":"T287","span":{"begin":1526,"end":1529},"obj":"CVCL_2501"},{"id":"T272","span":{"begin":1526,"end":1529},"obj":"GO:0047152"},{"id":"T281","span":{"begin":1526,"end":1529},"obj":"GO:0043791"},{"id":"T290","span":{"begin":1526,"end":1529},"obj":"GO:0043834"},{"id":"T306","span":{"begin":1526,"end":1533},"obj":"Q9XT90"},{"id":"T307","span":{"begin":1526,"end":1533},"obj":"P50281"},{"id":"T308","span":{"begin":1526,"end":1533},"obj":"Q9GLE4"},{"id":"T309","span":{"begin":1526,"end":1533},"obj":"PR:000010474"},{"id":"T310","span":{"begin":1526,"end":1533},"obj":"Q10739"},{"id":"T311","span":{"begin":1526,"end":1533},"obj":"Q95220"},{"id":"T313","span":{"begin":1526,"end":1533},"obj":"P53690"},{"id":"T312","span":{"begin":1526,"end":1533},"obj":"D053511"},{"id":"T316","span":{"begin":1530,"end":1533},"obj":"GO:0004235"},{"id":"T319","span":{"begin":1535,"end":1545},"obj":"SO:0000673"},{"id":"T320","span":{"begin":1571,"end":1579},"obj":"CVCL_0188"},{"id":"T321","span":{"begin":1575,"end":1579},"obj":"P51525"},{"id":"T324","span":{"begin":1575,"end":1579},"obj":"CHEBI:87146"},{"id":"T326","span":{"begin":1599,"end":1602},"obj":"CHEBI:340824"},{"id":"T329","span":{"begin":1599,"end":1602},"obj":"CHEBI:59761"},{"id":"T330","span":{"begin":1599,"end":1603},"obj":"PR:P08253"},{"id":"T331","span":{"begin":1599,"end":1603},"obj":"Q9GLE5"},{"id":"T332","span":{"begin":1599,"end":1603},"obj":"P08253"},{"id":"T333","span":{"begin":1599,"end":1603},"obj":"Q90611"},{"id":"T335","span":{"begin":1599,"end":1603},"obj":"PR:Q8MPP3"},{"id":"T336","span":{"begin":1599,"end":1603},"obj":"P33436"},{"id":"T337","span":{"begin":1599,"end":1603},"obj":"PR:Q90611"},{"id":"T338","span":{"begin":1599,"end":1603},"obj":"PR:P33436"},{"id":"T339","span":{"begin":1599,"end":1603},"obj":"PR:000010479"},{"id":"T340","span":{"begin":1599,"end":1603},"obj":"PR:P33434"},{"id":"T341","span":{"begin":1599,"end":1603},"obj":"P33434"},{"id":"T342","span":{"begin":1599,"end":1603},"obj":"P50757"},{"id":"T334","span":{"begin":1599,"end":1603},"obj":"GO:0004228"},{"id":"T347","span":{"begin":1613,"end":1616},"obj":"SO:0001439"},{"id":"T343","span":{"begin":1613,"end":1616},"obj":"CVCL_N817"},{"id":"T349","span":{"begin":1613,"end":1621},"obj":"C069860"},{"id":"T354","span":{"begin":1617,"end":1621},"obj":"PR:P08253"},{"id":"T355","span":{"begin":1617,"end":1621},"obj":"Q9GLE5"},{"id":"T356","span":{"begin":1617,"end":1621},"obj":"P08253"},{"id":"T357","span":{"begin":1617,"end":1621},"obj":"Q90611"},{"id":"T359","span":{"begin":1617,"end":1621},"obj":"PR:Q8MPP3"},{"id":"T360","span":{"begin":1617,"end":1621},"obj":"P33436"},{"id":"T361","span":{"begin":1617,"end":1621},"obj":"PR:Q90611"},{"id":"T362","span":{"begin":1617,"end":1621},"obj":"PR:P33436"},{"id":"T363","span":{"begin":1617,"end":1621},"obj":"PR:000010479"},{"id":"T364","span":{"begin":1617,"end":1621},"obj":"PR:P33434"},{"id":"T365","span":{"begin":1617,"end":1621},"obj":"P33434"},{"id":"T366","span":{"begin":1617,"end":1621},"obj":"P50757"},{"id":"T358","span":{"begin":1617,"end":1621},"obj":"GO:0004228"},{"id":"T389","span":{"begin":1648,"end":1651},"obj":"CVCL_2501"},{"id":"T374","span":{"begin":1648,"end":1651},"obj":"GO:0047152"},{"id":"T383","span":{"begin":1648,"end":1651},"obj":"GO:0043791"},{"id":"T392","span":{"begin":1648,"end":1651},"obj":"GO:0043834"},{"id":"T408","span":{"begin":1648,"end":1655},"obj":"Q9XT90"},{"id":"T409","span":{"begin":1648,"end":1655},"obj":"P50281"},{"id":"T410","span":{"begin":1648,"end":1655},"obj":"Q9GLE4"},{"id":"T411","span":{"begin":1648,"end":1655},"obj":"PR:000010474"},{"id":"T412","span":{"begin":1648,"end":1655},"obj":"Q10739"},{"id":"T413","span":{"begin":1648,"end":1655},"obj":"Q95220"},{"id":"T415","span":{"begin":1648,"end":1655},"obj":"P53690"},{"id":"T414","span":{"begin":1648,"end":1655},"obj":"D053511"},{"id":"T418","span":{"begin":1652,"end":1655},"obj":"GO:0004235"},{"id":"T421","span":{"begin":1731,"end":1739},"obj":"CVCL_0188"},{"id":"T422","span":{"begin":1735,"end":1739},"obj":"P51525"},{"id":"T425","span":{"begin":1735,"end":1739},"obj":"CHEBI:87146"},{"id":"T427","span":{"begin":1746,"end":1760},"obj":"P14894"},{"id":"T428","span":{"begin":1746,"end":1760},"obj":"P81461"},{"id":"T429","span":{"begin":1746,"end":1760},"obj":"P02866"},{"id":"T430","span":{"begin":1746,"end":1760},"obj":"P81460"},{"id":"T431","span":{"begin":1746,"end":1760},"obj":"D003208"},{"id":"T454","span":{"begin":1805,"end":1808},"obj":"CVCL_2501"},{"id":"T439","span":{"begin":1805,"end":1808},"obj":"GO:0047152"},{"id":"T448","span":{"begin":1805,"end":1808},"obj":"GO:0043791"},{"id":"T457","span":{"begin":1805,"end":1808},"obj":"GO:0043834"},{"id":"T473","span":{"begin":1805,"end":1812},"obj":"Q9XT90"},{"id":"T474","span":{"begin":1805,"end":1812},"obj":"P50281"},{"id":"T475","span":{"begin":1805,"end":1812},"obj":"Q9GLE4"},{"id":"T476","span":{"begin":1805,"end":1812},"obj":"PR:000010474"},{"id":"T477","span":{"begin":1805,"end":1812},"obj":"Q10739"},{"id":"T478","span":{"begin":1805,"end":1812},"obj":"Q95220"},{"id":"T480","span":{"begin":1805,"end":1812},"obj":"P53690"},{"id":"T479","span":{"begin":1805,"end":1812},"obj":"D053511"},{"id":"T483","span":{"begin":1809,"end":1812},"obj":"GO:0004235"},{"id":"T486","span":{"begin":1844,"end":1847},"obj":"CVCL_N817"},{"id":"T490","span":{"begin":1844,"end":1847},"obj":"SO:0001439"},{"id":"T492","span":{"begin":1844,"end":1852},"obj":"C069860"},{"id":"T497","span":{"begin":1848,"end":1852},"obj":"PR:P08253"},{"id":"T498","span":{"begin":1848,"end":1852},"obj":"Q9GLE5"},{"id":"T499","span":{"begin":1848,"end":1852},"obj":"P08253"},{"id":"T500","span":{"begin":1848,"end":1852},"obj":"Q90611"},{"id":"T502","span":{"begin":1848,"end":1852},"obj":"PR:Q8MPP3"},{"id":"T503","span":{"begin":1848,"end":1852},"obj":"P33436"},{"id":"T504","span":{"begin":1848,"end":1852},"obj":"PR:Q90611"},{"id":"T505","span":{"begin":1848,"end":1852},"obj":"PR:P33436"},{"id":"T506","span":{"begin":1848,"end":1852},"obj":"PR:000010479"},{"id":"T507","span":{"begin":1848,"end":1852},"obj":"PR:P33434"},{"id":"T508","span":{"begin":1848,"end":1852},"obj":"P33434"},{"id":"T509","span":{"begin":1848,"end":1852},"obj":"P50757"},{"id":"T501","span":{"begin":1848,"end":1852},"obj":"GO:0004228"},{"id":"T510","span":{"begin":1934,"end":1937},"obj":"CHEBI:340824"},{"id":"T513","span":{"begin":1934,"end":1937},"obj":"CHEBI:59761"},{"id":"T514","span":{"begin":1934,"end":1938},"obj":"PR:P08253"},{"id":"T515","span":{"begin":1934,"end":1938},"obj":"Q9GLE5"},{"id":"T516","span":{"begin":1934,"end":1938},"obj":"P08253"},{"id":"T517","span":{"begin":1934,"end":1938},"obj":"Q90611"},{"id":"T519","span":{"begin":1934,"end":1938},"obj":"PR:Q8MPP3"},{"id":"T520","span":{"begin":1934,"end":1938},"obj":"P33436"},{"id":"T521","span":{"begin":1934,"end":1938},"obj":"PR:Q90611"},{"id":"T522","span":{"begin":1934,"end":1938},"obj":"PR:P33436"},{"id":"T523","span":{"begin":1934,"end":1938},"obj":"PR:000010479"},{"id":"T524","span":{"begin":1934,"end":1938},"obj":"PR:P33434"},{"id":"T525","span":{"begin":1934,"end":1938},"obj":"P33434"},{"id":"T526","span":{"begin":1934,"end":1938},"obj":"P50757"},{"id":"T518","span":{"begin":1934,"end":1938},"obj":"GO:0004228"},{"id":"T527","span":{"begin":2001,"end":2006},"obj":"10090"},{"id":"T528","span":{"begin":2001,"end":2006},"obj":"D051379"},{"id":"T529","span":{"begin":2043,"end":2046},"obj":"CHEBI:340824"},{"id":"T532","span":{"begin":2043,"end":2046},"obj":"CHEBI:59761"},{"id":"T533","span":{"begin":2043,"end":2047},"obj":"PR:P08253"},{"id":"T534","span":{"begin":2043,"end":2047},"obj":"Q9GLE5"},{"id":"T535","span":{"begin":2043,"end":2047},"obj":"P08253"},{"id":"T536","span":{"begin":2043,"end":2047},"obj":"Q90611"},{"id":"T538","span":{"begin":2043,"end":2047},"obj":"PR:Q8MPP3"},{"id":"T539","span":{"begin":2043,"end":2047},"obj":"P33436"},{"id":"T540","span":{"begin":2043,"end":2047},"obj":"PR:Q90611"},{"id":"T541","span":{"begin":2043,"end":2047},"obj":"PR:P33436"},{"id":"T542","span":{"begin":2043,"end":2047},"obj":"PR:000010479"},{"id":"T543","span":{"begin":2043,"end":2047},"obj":"PR:P33434"},{"id":"T544","span":{"begin":2043,"end":2047},"obj":"P33434"},{"id":"T545","span":{"begin":2043,"end":2047},"obj":"P50757"},{"id":"T537","span":{"begin":2043,"end":2047},"obj":"GO:0004228"},{"id":"T568","span":{"begin":2052,"end":2055},"obj":"CVCL_2501"},{"id":"T553","span":{"begin":2052,"end":2055},"obj":"GO:0047152"},{"id":"T562","span":{"begin":2052,"end":2055},"obj":"GO:0043791"},{"id":"T571","span":{"begin":2052,"end":2055},"obj":"GO:0043834"},{"id":"T587","span":{"begin":2052,"end":2059},"obj":"Q9XT90"},{"id":"T588","span":{"begin":2052,"end":2059},"obj":"P50281"},{"id":"T589","span":{"begin":2052,"end":2059},"obj":"Q9GLE4"},{"id":"T590","span":{"begin":2052,"end":2059},"obj":"PR:000010474"},{"id":"T591","span":{"begin":2052,"end":2059},"obj":"Q10739"},{"id":"T592","span":{"begin":2052,"end":2059},"obj":"Q95220"},{"id":"T594","span":{"begin":2052,"end":2059},"obj":"P53690"},{"id":"T593","span":{"begin":2052,"end":2059},"obj":"D053511"},{"id":"T597","span":{"begin":2056,"end":2059},"obj":"GO:0004235"},{"id":"T600","span":{"begin":2060,"end":2064},"obj":"SO:0000704"},{"id":"T601","span":{"begin":2084,"end":2092},"obj":"CVCL_0188"},{"id":"T602","span":{"begin":2088,"end":2092},"obj":"P51525"},{"id":"T605","span":{"begin":2088,"end":2092},"obj":"CHEBI:87146"},{"id":"T607","span":{"begin":2153,"end":2161},"obj":"CVCL_0188"},{"id":"T608","span":{"begin":2157,"end":2161},"obj":"P51525"},{"id":"T611","span":{"begin":2157,"end":2161},"obj":"CHEBI:87146"},{"id":"T613","span":{"begin":2215,"end":2218},"obj":"CHEBI:340824"},{"id":"T616","span":{"begin":2215,"end":2218},"obj":"CHEBI:59761"},{"id":"T617","span":{"begin":2215,"end":2219},"obj":"PR:P08253"},{"id":"T618","span":{"begin":2215,"end":2219},"obj":"Q9GLE5"},{"id":"T619","span":{"begin":2215,"end":2219},"obj":"P08253"},{"id":"T620","span":{"begin":2215,"end":2219},"obj":"Q90611"},{"id":"T622","span":{"begin":2215,"end":2219},"obj":"PR:Q8MPP3"},{"id":"T623","span":{"begin":2215,"end":2219},"obj":"P33436"},{"id":"T624","span":{"begin":2215,"end":2219},"obj":"PR:Q90611"},{"id":"T625","span":{"begin":2215,"end":2219},"obj":"PR:P33436"},{"id":"T626","span":{"begin":2215,"end":2219},"obj":"PR:000010479"},{"id":"T627","span":{"begin":2215,"end":2219},"obj":"PR:P33434"},{"id":"T628","span":{"begin":2215,"end":2219},"obj":"P33434"},{"id":"T629","span":{"begin":2215,"end":2219},"obj":"P50757"},{"id":"T621","span":{"begin":2215,"end":2219},"obj":"GO:0004228"},{"id":"T652","span":{"begin":2242,"end":2245},"obj":"CVCL_2501"},{"id":"T637","span":{"begin":2242,"end":2245},"obj":"GO:0047152"},{"id":"T646","span":{"begin":2242,"end":2245},"obj":"GO:0043791"},{"id":"T655","span":{"begin":2242,"end":2245},"obj":"GO:0043834"},{"id":"T671","span":{"begin":2242,"end":2249},"obj":"Q9XT90"},{"id":"T672","span":{"begin":2242,"end":2249},"obj":"P50281"},{"id":"T673","span":{"begin":2242,"end":2249},"obj":"Q9GLE4"},{"id":"T674","span":{"begin":2242,"end":2249},"obj":"PR:000010474"},{"id":"T675","span":{"begin":2242,"end":2249},"obj":"Q10739"},{"id":"T676","span":{"begin":2242,"end":2249},"obj":"Q95220"},{"id":"T678","span":{"begin":2242,"end":2249},"obj":"P53690"},{"id":"T677","span":{"begin":2242,"end":2249},"obj":"D053511"},{"id":"T681","span":{"begin":2246,"end":2249},"obj":"GO:0004235"},{"id":"T684","span":{"begin":2254,"end":2262},"obj":"CL:0000056"},{"id":"T685","span":{"begin":2254,"end":2272},"obj":"GO:0051451"}],"attributes":[{"subj":"T1","pred":"source","obj":"c_corpus"},{"subj":"T2","pred":"source","obj":"c_corpus"},{"subj":"T3","pred":"source","obj":"c_corpus"},{"subj":"T5","pred":"source","obj":"c_corpus"},{"subj":"T6","pred":"source","obj":"c_corpus"},{"subj":"T7","pred":"source","obj":"c_corpus"},{"subj":"T8","pred":"source","obj":"c_corpus"},{"subj":"T9","pred":"source","obj":"c_corpus"},{"subj":"T10","pred":"source","obj":"c_corpus"},{"subj":"T11","pred":"source","obj":"c_corpus"},{"subj":"T12","pred":"source","obj":"c_corpus"},{"subj":"T13","pred":"source","obj":"c_corpus"},{"subj":"T16","pred":"source","obj":"c_corpus"},{"subj":"T18","pred":"source","obj":"c_corpus"},{"subj":"T19","pred":"source","obj":"c_corpus"},{"subj":"T20","pred":"source","obj":"c_corpus"},{"subj":"T22","pred":"source","obj":"c_corpus"},{"subj":"T23","pred":"source","obj":"c_corpus"},{"subj":"T24","pred":"source","obj":"c_corpus"},{"subj":"T27","pred":"source","obj":"c_corpus"},{"subj":"T29","pred":"source","obj":"c_corpus"},{"subj":"T30","pred":"source","obj":"c_corpus"},{"subj":"T31","pred":"source","obj":"c_corpus"},{"subj":"T33","pred":"source","obj":"c_corpus"},{"subj":"T34","pred":"source","obj":"c_corpus"},{"subj":"T35","pred":"source","obj":"c_corpus"},{"subj":"T32","pred":"source","obj":"c_corpus"},{"subj":"T37","pred":"source","obj":"c_corpus"},{"subj":"T38","pred":"source","obj":"c_corpus"},{"subj":"T39","pred":"source","obj":"c_corpus"},{"subj":"T40","pred":"source","obj":"c_corpus"},{"subj":"T41","pred":"source","obj":"c_corpus"},{"subj":"T42","pred":"source","obj":"c_corpus"},{"subj":"T45","pred":"source","obj":"c_corpus"},{"subj":"T46","pred":"source","obj":"c_corpus"},{"subj":"T49","pred":"source","obj":"c_corpus"},{"subj":"T68","pred":"source","obj":"c_corpus"},{"subj":"T66","pred":"source","obj":"c_corpus"},{"subj":"T69","pred":"source","obj":"c_corpus"},{"subj":"T67","pred":"source","obj":"c_corpus"},{"subj":"T70","pred":"source","obj":"c_corpus"},{"subj":"T71","pred":"source","obj":"c_corpus"},{"subj":"T72","pred":"source","obj":"c_corpus"},{"subj":"T73","pred":"source","obj":"c_corpus"},{"subj":"T74","pred":"source","obj":"c_corpus"},{"subj":"T77","pred":"source","obj":"c_corpus"},{"subj":"T79","pred":"source","obj":"c_corpus"},{"subj":"T80","pred":"source","obj":"c_corpus"},{"subj":"T81","pred":"source","obj":"c_corpus"},{"subj":"T82","pred":"source","obj":"c_corpus"},{"subj":"T83","pred":"source","obj":"c_corpus"},{"subj":"T84","pred":"source","obj":"c_corpus"},{"subj":"T85","pred":"source","obj":"c_corpus"},{"subj":"T86","pred":"source","obj":"c_corpus"},{"subj":"T89","pred":"source","obj":"c_corpus"},{"subj":"T87","pred":"source","obj":"c_corpus"},{"subj":"T90","pred":"source","obj":"c_corpus"},{"subj":"T88","pred":"source","obj":"c_corpus"},{"subj":"T93","pred":"source","obj":"c_corpus"},{"subj":"T91","pred":"source","obj":"c_corpus"},{"subj":"T92","pred":"source","obj":"c_corpus"},{"subj":"T94","pred":"source","obj":"c_corpus"},{"subj":"T95","pred":"source","obj":"c_corpus"},{"subj":"T98","pred":"source","obj":"c_corpus"},{"subj":"T100","pred":"source","obj":"c_corpus"},{"subj":"T101","pred":"source","obj":"c_corpus"},{"subj":"T102","pred":"source","obj":"c_corpus"},{"subj":"T103","pred":"source","obj":"c_corpus"},{"subj":"T104","pred":"source","obj":"c_corpus"},{"subj":"T107","pred":"source","obj":"c_corpus"},{"subj":"T108","pred":"source","obj":"c_corpus"},{"subj":"T109","pred":"source","obj":"c_corpus"},{"subj":"T110","pred":"source","obj":"c_corpus"},{"subj":"T111","pred":"source","obj":"c_corpus"},{"subj":"T113","pred":"source","obj":"c_corpus"},{"subj":"T114","pred":"source","obj":"c_corpus"},{"subj":"T115","pred":"source","obj":"c_corpus"},{"subj":"T116","pred":"source","obj":"c_corpus"},{"subj":"T117","pred":"source","obj":"c_corpus"},{"subj":"T118","pred":"source","obj":"c_corpus"},{"subj":"T119","pred":"source","obj":"c_corpus"},{"subj":"T120","pred":"source","obj":"c_corpus"},{"subj":"T112","pred":"source","obj":"c_corpus"},{"subj":"T123","pred":"source","obj":"c_corpus"},{"subj":"T124","pred":"source","obj":"c_corpus"},{"subj":"T126","pred":"source","obj":"c_corpus"},{"subj":"T127","pred":"source","obj":"c_corpus"},{"subj":"T128","pred":"source","obj":"c_corpus"},{"subj":"T129","pred":"source","obj":"c_corpus"},{"subj":"T125","pred":"source","obj":"c_corpus"},{"subj":"T130","pred":"source","obj":"c_corpus"},{"subj":"T131","pred":"source","obj":"c_corpus"},{"subj":"T132","pred":"source","obj":"c_corpus"},{"subj":"T133","pred":"source","obj":"c_corpus"},{"subj":"T135","pred":"source","obj":"c_corpus"},{"subj":"T136","pred":"source","obj":"c_corpus"},{"subj":"T137","pred":"source","obj":"c_corpus"},{"subj":"T138","pred":"source","obj":"c_corpus"},{"subj":"T134","pred":"source","obj":"c_corpus"},{"subj":"T140","pred":"source","obj":"c_corpus"},{"subj":"T167","pred":"source","obj":"c_corpus"},{"subj":"T152","pred":"source","obj":"c_corpus"},{"subj":"T161","pred":"source","obj":"c_corpus"},{"subj":"T170","pred":"source","obj":"c_corpus"},{"subj":"T186","pred":"source","obj":"c_corpus"},{"subj":"T187","pred":"source","obj":"c_corpus"},{"subj":"T188","pred":"source","obj":"c_corpus"},{"subj":"T189","pred":"source","obj":"c_corpus"},{"subj":"T190","pred":"source","obj":"c_corpus"},{"subj":"T191","pred":"source","obj":"c_corpus"},{"subj":"T193","pred":"source","obj":"c_corpus"},{"subj":"T192","pred":"source","obj":"c_corpus"},{"subj":"T196","pred":"source","obj":"c_corpus"},{"subj":"T199","pred":"source","obj":"c_corpus"},{"subj":"T202","pred":"source","obj":"c_corpus"},{"subj":"T203","pred":"source","obj":"c_corpus"},{"subj":"T204","pred":"source","obj":"c_corpus"},{"subj":"T205","pred":"source","obj":"c_corpus"},{"subj":"T206","pred":"source","obj":"c_corpus"},{"subj":"T208","pred":"source","obj":"c_corpus"},{"subj":"T209","pred":"source","obj":"c_corpus"},{"subj":"T210","pred":"source","obj":"c_corpus"},{"subj":"T211","pred":"source","obj":"c_corpus"},{"subj":"T212","pred":"source","obj":"c_corpus"},{"subj":"T213","pred":"source","obj":"c_corpus"},{"subj":"T214","pred":"source","obj":"c_corpus"},{"subj":"T215","pred":"source","obj":"c_corpus"},{"subj":"T207","pred":"source","obj":"c_corpus"},{"subj":"T216","pred":"source","obj":"c_corpus"},{"subj":"T217","pred":"source","obj":"c_corpus"},{"subj":"T220","pred":"source","obj":"c_corpus"},{"subj":"T221","pred":"source","obj":"c_corpus"},{"subj":"T222","pred":"source","obj":"c_corpus"},{"subj":"T223","pred":"source","obj":"c_corpus"},{"subj":"T224","pred":"source","obj":"c_corpus"},{"subj":"T225","pred":"source","obj":"c_corpus"},{"subj":"T226","pred":"source","obj":"c_corpus"},{"subj":"T227","pred":"source","obj":"c_corpus"},{"subj":"T228","pred":"source","obj":"c_corpus"},{"subj":"T230","pred":"source","obj":"c_corpus"},{"subj":"T231","pred":"source","obj":"c_corpus"},{"subj":"T232","pred":"source","obj":"c_corpus"},{"subj":"T229","pred":"source","obj":"c_corpus"},{"subj":"T236","pred":"source","obj":"c_corpus"},{"subj":"T237","pred":"source","obj":"c_corpus"},{"subj":"T238","pred":"source","obj":"c_corpus"},{"subj":"T239","pred":"source","obj":"c_corpus"},{"subj":"T240","pred":"source","obj":"c_corpus"},{"subj":"T241","pred":"source","obj":"c_corpus"},{"subj":"T242","pred":"source","obj":"c_corpus"},{"subj":"T235","pred":"source","obj":"c_corpus"},{"subj":"T243","pred":"source","obj":"c_corpus"},{"subj":"T245","pred":"source","obj":"c_corpus"},{"subj":"T246","pred":"source","obj":"c_corpus"},{"subj":"T247","pred":"source","obj":"c_corpus"},{"subj":"T248","pred":"source","obj":"c_corpus"},{"subj":"T249","pred":"source","obj":"c_corpus"},{"subj":"T250","pred":"source","obj":"c_corpus"},{"subj":"T251","pred":"source","obj":"c_corpus"},{"subj":"T244","pred":"source","obj":"c_corpus"},{"subj":"T253","pred":"source","obj":"c_corpus"},{"subj":"T259","pred":"source","obj":"c_corpus"},{"subj":"T258","pred":"source","obj":"c_corpus"},{"subj":"T260","pred":"source","obj":"c_corpus"},{"subj":"T263","pred":"source","obj":"c_corpus"},{"subj":"T261","pred":"source","obj":"c_corpus"},{"subj":"T264","pred":"source","obj":"c_corpus"},{"subj":"T262","pred":"source","obj":"c_corpus"},{"subj":"T287","pred":"source","obj":"c_corpus"},{"subj":"T272","pred":"source","obj":"c_corpus"},{"subj":"T281","pred":"source","obj":"c_corpus"},{"subj":"T290","pred":"source","obj":"c_corpus"},{"subj":"T306","pred":"source","obj":"c_corpus"},{"subj":"T307","pred":"source","obj":"c_corpus"},{"subj":"T308","pred":"source","obj":"c_corpus"},{"subj":"T309","pred":"source","obj":"c_corpus"},{"subj":"T310","pred":"source","obj":"c_corpus"},{"subj":"T311","pred":"source","obj":"c_corpus"},{"subj":"T313","pred":"source","obj":"c_corpus"},{"subj":"T312","pred":"source","obj":"c_corpus"},{"subj":"T316","pred":"source","obj":"c_corpus"},{"subj":"T319","pred":"source","obj":"c_corpus"},{"subj":"T320","pred":"source","obj":"c_corpus"},{"subj":"T321","pred":"source","obj":"c_corpus"},{"subj":"T324","pred":"source","obj":"c_corpus"},{"subj":"T326","pred":"source","obj":"c_corpus"},{"subj":"T329","pred":"source","obj":"c_corpus"},{"subj":"T330","pred":"source","obj":"c_corpus"},{"subj":"T331","pred":"source","obj":"c_corpus"},{"subj":"T332","pred":"source","obj":"c_corpus"},{"subj":"T333","pred":"source","obj":"c_corpus"},{"subj":"T335","pred":"source","obj":"c_corpus"},{"subj":"T336","pred":"source","obj":"c_corpus"},{"subj":"T337","pred":"source","obj":"c_corpus"},{"subj":"T338","pred":"source","obj":"c_corpus"},{"subj":"T339","pred":"source","obj":"c_corpus"},{"subj":"T340","pred":"source","obj":"c_corpus"},{"subj":"T341","pred":"source","obj":"c_corpus"},{"subj":"T342","pred":"source","obj":"c_corpus"},{"subj":"T334","pred":"source","obj":"c_corpus"},{"subj":"T347","pred":"source","obj":"c_corpus"},{"subj":"T343","pred":"source","obj":"c_corpus"},{"subj":"T349","pred":"source","obj":"c_corpus"},{"subj":"T354","pred":"source","obj":"c_corpus"},{"subj":"T355","pred":"source","obj":"c_corpus"},{"subj":"T356","pred":"source","obj":"c_corpus"},{"subj":"T357","pred":"source","obj":"c_corpus"},{"subj":"T359","pred":"source","obj":"c_corpus"},{"subj":"T360","pred":"source","obj":"c_corpus"},{"subj":"T361","pred":"source","obj":"c_corpus"},{"subj":"T362","pred":"source","obj":"c_corpus"},{"subj":"T363","pred":"source","obj":"c_corpus"},{"subj":"T364","pred":"source","obj":"c_corpus"},{"subj":"T365","pred":"source","obj":"c_corpus"},{"subj":"T366","pred":"source","obj":"c_corpus"},{"subj":"T358","pred":"source","obj":"c_corpus"},{"subj":"T389","pred":"source","obj":"c_corpus"},{"subj":"T374","pred":"source","obj":"c_corpus"},{"subj":"T383","pred":"source","obj":"c_corpus"},{"subj":"T392","pred":"source","obj":"c_corpus"},{"subj":"T408","pred":"source","obj":"c_corpus"},{"subj":"T409","pred":"source","obj":"c_corpus"},{"subj":"T410","pred":"source","obj":"c_corpus"},{"subj":"T411","pred":"source","obj":"c_corpus"},{"subj":"T412","pred":"source","obj":"c_corpus"},{"subj":"T413","pred":"source","obj":"c_corpus"},{"subj":"T415","pred":"source","obj":"c_corpus"},{"subj":"T414","pred":"source","obj":"c_corpus"},{"subj":"T418","pred":"source","obj":"c_corpus"},{"subj":"T421","pred":"source","obj":"c_corpus"},{"subj":"T422","pred":"source","obj":"c_corpus"},{"subj":"T425","pred":"source","obj":"c_corpus"},{"subj":"T427","pred":"source","obj":"c_corpus"},{"subj":"T428","pred":"source","obj":"c_corpus"},{"subj":"T429","pred":"source","obj":"c_corpus"},{"subj":"T430","pred":"source","obj":"c_corpus"},{"subj":"T431","pred":"source","obj":"c_corpus"},{"subj":"T454","pred":"source","obj":"c_corpus"},{"subj":"T439","pred":"source","obj":"c_corpus"},{"subj":"T448","pred":"source","obj":"c_corpus"},{"subj":"T457","pred":"source","obj":"c_corpus"},{"subj":"T473","pred":"source","obj":"c_corpus"},{"subj":"T474","pred":"source","obj":"c_corpus"},{"subj":"T475","pred":"source","obj":"c_corpus"},{"subj":"T476","pred":"source","obj":"c_corpus"},{"subj":"T477","pred":"source","obj":"c_corpus"},{"subj":"T478","pred":"source","obj":"c_corpus"},{"subj":"T480","pred":"source","obj":"c_corpus"},{"subj":"T479","pred":"source","obj":"c_corpus"},{"subj":"T483","pred":"source","obj":"c_corpus"},{"subj":"T486","pred":"source","obj":"c_corpus"},{"subj":"T490","pred":"source","obj":"c_corpus"},{"subj":"T492","pred":"source","obj":"c_corpus"},{"subj":"T497","pred":"source","obj":"c_corpus"},{"subj":"T498","pred":"source","obj":"c_corpus"},{"subj":"T499","pred":"source","obj":"c_corpus"},{"subj":"T500","pred":"source","obj":"c_corpus"},{"subj":"T502","pred":"source","obj":"c_corpus"},{"subj":"T503","pred":"source","obj":"c_corpus"},{"subj":"T504","pred":"source","obj":"c_corpus"},{"subj":"T505","pred":"source","obj":"c_corpus"},{"subj":"T506","pred":"source","obj":"c_corpus"},{"subj":"T507","pred":"source","obj":"c_corpus"},{"subj":"T508","pred":"source","obj":"c_corpus"},{"subj":"T509","pred":"source","obj":"c_corpus"},{"subj":"T501","pred":"source","obj":"c_corpus"},{"subj":"T510","pred":"source","obj":"c_corpus"},{"subj":"T513","pred":"source","obj":"c_corpus"},{"subj":"T514","pred":"source","obj":"c_corpus"},{"subj":"T515","pred":"source","obj":"c_corpus"},{"subj":"T516","pred":"source","obj":"c_corpus"},{"subj":"T517","pred":"source","obj":"c_corpus"},{"subj":"T519","pred":"source","obj":"c_corpus"},{"subj":"T520","pred":"source","obj":"c_corpus"},{"subj":"T521","pred":"source","obj":"c_corpus"},{"subj":"T522","pred":"source","obj":"c_corpus"},{"subj":"T523","pred":"source","obj":"c_corpus"},{"subj":"T524","pred":"source","obj":"c_corpus"},{"subj":"T525","pred":"source","obj":"c_corpus"},{"subj":"T526","pred":"source","obj":"c_corpus"},{"subj":"T518","pred":"source","obj":"c_corpus"},{"subj":"T527","pred":"source","obj":"c_corpus"},{"subj":"T528","pred":"source","obj":"c_corpus"},{"subj":"T529","pred":"source","obj":"c_corpus"},{"subj":"T532","pred":"source","obj":"c_corpus"},{"subj":"T533","pred":"source","obj":"c_corpus"},{"subj":"T534","pred":"source","obj":"c_corpus"},{"subj":"T535","pred":"source","obj":"c_corpus"},{"subj":"T536","pred":"source","obj":"c_corpus"},{"subj":"T538","pred":"source","obj":"c_corpus"},{"subj":"T539","pred":"source","obj":"c_corpus"},{"subj":"T540","pred":"source","obj":"c_corpus"},{"subj":"T541","pred":"source","obj":"c_corpus"},{"subj":"T542","pred":"source","obj":"c_corpus"},{"subj":"T543","pred":"source","obj":"c_corpus"},{"subj":"T544","pred":"source","obj":"c_corpus"},{"subj":"T545","pred":"source","obj":"c_corpus"},{"subj":"T537","pred":"source","obj":"c_corpus"},{"subj":"T568","pred":"source","obj":"c_corpus"},{"subj":"T553","pred":"source","obj":"c_corpus"},{"subj":"T562","pred":"source","obj":"c_corpus"},{"subj":"T571","pred":"source","obj":"c_corpus"},{"subj":"T587","pred":"source","obj":"c_corpus"},{"subj":"T588","pred":"source","obj":"c_corpus"},{"subj":"T589","pred":"source","obj":"c_corpus"},{"subj":"T590","pred":"source","obj":"c_corpus"},{"subj":"T591","pred":"source","obj":"c_corpus"},{"subj":"T592","pred":"source","obj":"c_corpus"},{"subj":"T594","pred":"source","obj":"c_corpus"},{"subj":"T593","pred":"source","obj":"c_corpus"},{"subj":"T597","pred":"source","obj":"c_corpus"},{"subj":"T600","pred":"source","obj":"c_corpus"},{"subj":"T601","pred":"source","obj":"c_corpus"},{"subj":"T602","pred":"source","obj":"c_corpus"},{"subj":"T605","pred":"source","obj":"c_corpus"},{"subj":"T607","pred":"source","obj":"c_corpus"},{"subj":"T608","pred":"source","obj":"c_corpus"},{"subj":"T611","pred":"source","obj":"c_corpus"},{"subj":"T613","pred":"source","obj":"c_corpus"},{"subj":"T616","pred":"source","obj":"c_corpus"},{"subj":"T617","pred":"source","obj":"c_corpus"},{"subj":"T618","pred":"source","obj":"c_corpus"},{"subj":"T619","pred":"source","obj":"c_corpus"},{"subj":"T620","pred":"source","obj":"c_corpus"},{"subj":"T622","pred":"source","obj":"c_corpus"},{"subj":"T623","pred":"source","obj":"c_corpus"},{"subj":"T624","pred":"source","obj":"c_corpus"},{"subj":"T625","pred":"source","obj":"c_corpus"},{"subj":"T626","pred":"source","obj":"c_corpus"},{"subj":"T627","pred":"source","obj":"c_corpus"},{"subj":"T628","pred":"source","obj":"c_corpus"},{"subj":"T629","pred":"source","obj":"c_corpus"},{"subj":"T621","pred":"source","obj":"c_corpus"},{"subj":"T652","pred":"source","obj":"c_corpus"},{"subj":"T637","pred":"source","obj":"c_corpus"},{"subj":"T646","pred":"source","obj":"c_corpus"},{"subj":"T655","pred":"source","obj":"c_corpus"},{"subj":"T671","pred":"source","obj":"c_corpus"},{"subj":"T672","pred":"source","obj":"c_corpus"},{"subj":"T673","pred":"source","obj":"c_corpus"},{"subj":"T674","pred":"source","obj":"c_corpus"},{"subj":"T675","pred":"source","obj":"c_corpus"},{"subj":"T676","pred":"source","obj":"c_corpus"},{"subj":"T678","pred":"source","obj":"c_corpus"},{"subj":"T677","pred":"source","obj":"c_corpus"},{"subj":"T681","pred":"source","obj":"c_corpus"},{"subj":"T684","pred":"source","obj":"c_corpus"},{"subj":"T685","pred":"source","obj":"c_corpus"}]},{"project":"UseCases_ArguminSci_Discourse","denotations":[{"id":"T1","span":{"begin":0,"end":87},"obj":"DRI_Background"},{"id":"T2","span":{"begin":88,"end":207},"obj":"DRI_Background"},{"id":"T3","span":{"begin":208,"end":424},"obj":"DRI_Approach"},{"id":"T4","span":{"begin":425,"end":654},"obj":"DRI_Approach"},{"id":"T5","span":{"begin":655,"end":754},"obj":"DRI_Approach"},{"id":"T6","span":{"begin":755,"end":926},"obj":"DRI_Approach"},{"id":"T7","span":{"begin":927,"end":1027},"obj":"DRI_Background"},{"id":"T8","span":{"begin":1028,"end":1139},"obj":"DRI_Background"},{"id":"T9","span":{"begin":1140,"end":1364},"obj":"DRI_Outcome"},{"id":"T10","span":{"begin":1365,"end":1481},"obj":"DRI_Approach"},{"id":"T11","span":{"begin":1482,"end":1598},"obj":"DRI_Approach"},{"id":"T12","span":{"begin":1599,"end":1611},"obj":"Token_Label.OUTSIDE"},{"id":"T13","span":{"begin":1612,"end":1656},"obj":"DRI_Approach"},{"id":"T14","span":{"begin":1657,"end":1900},"obj":"DRI_Approach"},{"id":"T15","span":{"begin":1901,"end":2025},"obj":"DRI_Background"},{"id":"T16","span":{"begin":2026,"end":2163},"obj":"DRI_Approach"},{"id":"T17","span":{"begin":2164,"end":2273},"obj":"DRI_Unspecified"}],"attributes":[{"subj":"T1","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T2","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T3","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T4","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T5","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T6","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T7","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T8","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T9","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T10","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T11","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T12","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T13","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T14","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T15","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T16","pred":"source","obj":"UseCases_ArguminSci_Discourse"},{"subj":"T17","pred":"source","obj":"UseCases_ArguminSci_Discourse"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"c_corpus","color":"#9e93ec","default":true},{"id":"UseCases_ArguminSci_Discourse","color":"#a2ec93"}]}]}}