PubMed:10872036
Annnotations
c_corpus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 18-45 | D002285 | denotes | atypical ductal hyperplasia |
T2 | 18-45 | D002285 | denotes | atypical ductal hyperplasia |
T5 | 50-71 | D002285 | denotes | intraductal carcinoma |
T6 | 50-71 | D002285 | denotes | intraductal carcinoma |
T9 | 79-85 | UBERON:0000310 | denotes | breast |
T10 | 173-182 | UBERON:3010449 | denotes | organizer |
T11 | 173-182 | UBERON:0003062 | denotes | organizer |
T12 | 173-182 | UBERON:3010457 | denotes | organizer |
T13 | 192-198 | C051963 | denotes | AgNORs |
T14 | 192-198 | C051963 | denotes | AgNORs |
T15 | 203-230 | D002285 | denotes | atypical ductal hyperplasia |
T16 | 203-230 | D002285 | denotes | atypical ductal hyperplasia |
T19 | 232-235 | P0A388 | denotes | ADH |
T20 | 232-235 | PR:P06525 | denotes | ADH |
T21 | 232-235 | Q8NXU1 | denotes | ADH |
T22 | 232-235 | Q6GBM4 | denotes | ADH |
T23 | 232-235 | Q47945 | denotes | ADH |
T24 | 232-235 | P0A389 | denotes | ADH |
T25 | 232-235 | Q5HRD6 | denotes | ADH |
T26 | 232-235 | P28036 | denotes | ADH |
T27 | 232-235 | P42327 | denotes | ADH |
T28 | 232-235 | PR:P00332 | denotes | ADH |
T31 | 232-235 | P81786 | denotes | ADH |
T32 | 232-235 | P18278 | denotes | ADH |
T33 | 232-235 | Q44002 | denotes | ADH |
T34 | 232-235 | Q7A742 | denotes | ADH |
T35 | 232-235 | O05542 | denotes | ADH |
T36 | 232-235 | Q2YSX0 | denotes | ADH |
T37 | 232-235 | Q6GJ63 | denotes | ADH |
T38 | 232-235 | PR:P00334 | denotes | ADH |
T40 | 232-235 | Q24857 | denotes | ADH |
T41 | 232-235 | Q8CQ56 | denotes | ADH |
T42 | 232-235 | Q2FJ31 | denotes | ADH |
T43 | 232-235 | Q2G0G1 | denotes | ADH |
T44 | 232-235 | PR:Q2G0G1 | denotes | ADH |
T46 | 232-235 | Q5HI63 | denotes | ADH |
T47 | 232-235 | Q99W07 | denotes | ADH |
T48 | 232-235 | Q04983 | denotes | ADH |
T29 | 232-235 | CHEBI:34543 | denotes | ADH |
T45 | 232-235 | CHEBI:9937 | denotes | ADH |
T30 | 232-235 | GO:0047636 | denotes | ADH |
T39 | 232-235 | GO:0004022 | denotes | ADH |
T51 | 238-262 | D002285 | denotes | ductal carcinoma in situ |
T52 | 238-262 | D002285 | denotes | ductal carcinoma in situ |
T58 | 264-268 | CVCL_5552 | denotes | DCIS |
T57 | 264-268 | D002285 | denotes | DCIS |
T59 | 264-268 | D002285 | denotes | DCIS |
T60 | 288-304 | D044584 | denotes | ductal carcinoma |
T61 | 288-304 | D044584 | denotes | ductal carcinoma |
T64 | 306-310 | CHEBI:81482 | denotes | MDCA |
T65 | 319-325 | UBERON:0000310 | denotes | breast |
T66 | 399-405 | UBERON:0000310 | denotes | breast |
T67 | 406-409 | P0A388 | denotes | ADH |
T68 | 406-409 | PR:P06525 | denotes | ADH |
T69 | 406-409 | Q8NXU1 | denotes | ADH |
T70 | 406-409 | Q6GBM4 | denotes | ADH |
T71 | 406-409 | Q47945 | denotes | ADH |
T72 | 406-409 | P0A389 | denotes | ADH |
T73 | 406-409 | Q5HRD6 | denotes | ADH |
T74 | 406-409 | P28036 | denotes | ADH |
T75 | 406-409 | P42327 | denotes | ADH |
T76 | 406-409 | PR:P00332 | denotes | ADH |
T79 | 406-409 | P81786 | denotes | ADH |
T80 | 406-409 | P18278 | denotes | ADH |
T81 | 406-409 | Q44002 | denotes | ADH |
T82 | 406-409 | Q7A742 | denotes | ADH |
T83 | 406-409 | O05542 | denotes | ADH |
T84 | 406-409 | Q2YSX0 | denotes | ADH |
T85 | 406-409 | Q6GJ63 | denotes | ADH |
T86 | 406-409 | PR:P00334 | denotes | ADH |
T88 | 406-409 | Q24857 | denotes | ADH |
T89 | 406-409 | Q8CQ56 | denotes | ADH |
T90 | 406-409 | Q2FJ31 | denotes | ADH |
T91 | 406-409 | Q2G0G1 | denotes | ADH |
T92 | 406-409 | PR:Q2G0G1 | denotes | ADH |
T94 | 406-409 | Q5HI63 | denotes | ADH |
T95 | 406-409 | Q99W07 | denotes | ADH |
T96 | 406-409 | Q04983 | denotes | ADH |
T77 | 406-409 | CHEBI:34543 | denotes | ADH |
T93 | 406-409 | CHEBI:9937 | denotes | ADH |
T78 | 406-409 | GO:0047636 | denotes | ADH |
T87 | 406-409 | GO:0004022 | denotes | ADH |
T98 | 414-418 | CVCL_5552 | denotes | DCIS |
T97 | 414-418 | D002285 | denotes | DCIS |
T99 | 414-418 | D002285 | denotes | DCIS |
T100 | 435-439 | CHEBI:81482 | denotes | MDCA |
T101 | 488-494 | CHEBI:33252 | denotes | nuclei |
T102 | 509-518 | UBERON:3010449 | denotes | organizer |
T103 | 509-518 | UBERON:0003062 | denotes | organizer |
T104 | 509-518 | UBERON:3010457 | denotes | organizer |
T105 | 586-594 | D004967 | denotes | estrogen |
T106 | 586-594 | D004967 | denotes | estrogen |
T107 | 586-594 | CHEBI:50114 | denotes | estrogen |
T108 | 586-603 | Q9PVZ9 | denotes | estrogen receptor |
T109 | 586-603 | Q9YHT3 | denotes | estrogen receptor |
T110 | 586-603 | P57717 | denotes | estrogen receptor |
T111 | 586-603 | Q9QZJ5 | denotes | estrogen receptor |
T112 | 586-603 | Q29040 | denotes | estrogen receptor |
T113 | 586-603 | P49886 | denotes | estrogen receptor |
T114 | 586-603 | P50240 | denotes | estrogen receptor |
T115 | 586-603 | Q91424 | denotes | estrogen receptor |
T116 | 586-603 | Q9YHZ7 | denotes | estrogen receptor |
T117 | 586-603 | P06211 | denotes | estrogen receptor |
T118 | 586-603 | P16058 | denotes | estrogen receptor |
T119 | 586-603 | P50242 | denotes | estrogen receptor |
T120 | 586-603 | Q53AD2 | denotes | estrogen receptor |
T121 | 586-603 | P49885 | denotes | estrogen receptor |
T122 | 586-603 | P49884 | denotes | estrogen receptor |
T123 | 586-603 | P19785 | denotes | estrogen receptor |
T124 | 586-603 | Q91250 | denotes | estrogen receptor |
T125 | 586-603 | P81559 | denotes | estrogen receptor |
T126 | 586-603 | Q9TV98 | denotes | estrogen receptor |
T127 | 586-603 | PR:000007204 | denotes | estrogen receptor |
T128 | 586-603 | Q9YH33 | denotes | estrogen receptor |
T129 | 586-603 | P50241 | denotes | estrogen receptor |
T130 | 586-603 | P06212 | denotes | estrogen receptor |
T131 | 586-603 | P03372 | denotes | estrogen receptor |
T132 | 586-603 | O42132 | denotes | estrogen receptor |
T133 | 586-603 | P57753 | denotes | estrogen receptor |
T134 | 595-616 | D011980 | denotes | receptor/progesterone |
T136 | 604-616 | 8727 | denotes | progesterone |
T139 | 604-625 | Q9GLW0 | denotes | progesterone receptor |
T140 | 604-625 | A7XW16 | denotes | progesterone receptor |
T141 | 604-625 | A7X8C2 | denotes | progesterone receptor |
T142 | 604-625 | Q00175 | denotes | progesterone receptor |
T143 | 604-625 | A7X8B5 | denotes | progesterone receptor |
T144 | 604-625 | Q8AYI2 | denotes | progesterone receptor |
T145 | 604-625 | A7X8C7 | denotes | progesterone receptor |
T146 | 604-625 | Q63449 | denotes | progesterone receptor |
T147 | 604-625 | A7X8C9 | denotes | progesterone receptor |
T148 | 604-625 | Q28590 | denotes | progesterone receptor |
T149 | 604-625 | A7X8B9 | denotes | progesterone receptor |
T150 | 604-625 | A7X8D4 | denotes | progesterone receptor |
T151 | 604-625 | A7X8B3 | denotes | progesterone receptor |
T152 | 604-625 | P07812 | denotes | progesterone receptor |
T153 | 604-625 | A7XW20 | denotes | progesterone receptor |
T154 | 604-625 | A7X8B7 | denotes | progesterone receptor |
T155 | 604-625 | A7XW25 | denotes | progesterone receptor |
T156 | 604-625 | P06401 | denotes | progesterone receptor |
T157 | 604-625 | PR:000012621 | denotes | progesterone receptor |
T158 | 604-625 | P79373 | denotes | progesterone receptor |
T159 | 604-625 | P06186 | denotes | progesterone receptor |
T160 | 604-625 | A7X8C4 | denotes | progesterone receptor |
T162 | 604-625 | A7X8D2 | denotes | progesterone receptor |
T161 | 604-625 | D011980 | denotes | progesterone receptor |
T163 | 771-774 | P0A388 | denotes | ADH |
T164 | 771-774 | PR:P06525 | denotes | ADH |
T165 | 771-774 | Q8NXU1 | denotes | ADH |
T166 | 771-774 | Q6GBM4 | denotes | ADH |
T167 | 771-774 | Q47945 | denotes | ADH |
T168 | 771-774 | P0A389 | denotes | ADH |
T169 | 771-774 | Q5HRD6 | denotes | ADH |
T170 | 771-774 | P28036 | denotes | ADH |
T171 | 771-774 | P42327 | denotes | ADH |
T172 | 771-774 | PR:P00332 | denotes | ADH |
T175 | 771-774 | P81786 | denotes | ADH |
T176 | 771-774 | P18278 | denotes | ADH |
T177 | 771-774 | Q44002 | denotes | ADH |
T178 | 771-774 | Q7A742 | denotes | ADH |
T179 | 771-774 | O05542 | denotes | ADH |
T180 | 771-774 | Q2YSX0 | denotes | ADH |
T181 | 771-774 | Q6GJ63 | denotes | ADH |
T182 | 771-774 | PR:P00334 | denotes | ADH |
T184 | 771-774 | Q24857 | denotes | ADH |
T185 | 771-774 | Q8CQ56 | denotes | ADH |
T186 | 771-774 | Q2FJ31 | denotes | ADH |
T187 | 771-774 | Q2G0G1 | denotes | ADH |
T188 | 771-774 | PR:Q2G0G1 | denotes | ADH |
T190 | 771-774 | Q5HI63 | denotes | ADH |
T191 | 771-774 | Q99W07 | denotes | ADH |
T192 | 771-774 | Q04983 | denotes | ADH |
T173 | 771-774 | CHEBI:34543 | denotes | ADH |
T189 | 771-774 | CHEBI:9937 | denotes | ADH |
T174 | 771-774 | GO:0047636 | denotes | ADH |
T183 | 771-774 | GO:0004022 | denotes | ADH |
T194 | 778-782 | CVCL_5552 | denotes | DCIS |
T193 | 778-782 | D002285 | denotes | DCIS |
T195 | 778-782 | D002285 | denotes | DCIS |
T197 | 829-833 | CVCL_5552 | denotes | DCIS |
T196 | 829-833 | D002285 | denotes | DCIS |
T198 | 829-833 | D002285 | denotes | DCIS |
T199 | 874-877 | P0A388 | denotes | ADH |
T200 | 874-877 | PR:P06525 | denotes | ADH |
T201 | 874-877 | Q8NXU1 | denotes | ADH |
T202 | 874-877 | Q6GBM4 | denotes | ADH |
T203 | 874-877 | Q47945 | denotes | ADH |
T204 | 874-877 | P0A389 | denotes | ADH |
T205 | 874-877 | Q5HRD6 | denotes | ADH |
T206 | 874-877 | P28036 | denotes | ADH |
T207 | 874-877 | P42327 | denotes | ADH |
T208 | 874-877 | PR:P00332 | denotes | ADH |
T211 | 874-877 | P81786 | denotes | ADH |
T212 | 874-877 | P18278 | denotes | ADH |
T213 | 874-877 | Q44002 | denotes | ADH |
T214 | 874-877 | Q7A742 | denotes | ADH |
T215 | 874-877 | O05542 | denotes | ADH |
T216 | 874-877 | Q2YSX0 | denotes | ADH |
T217 | 874-877 | Q6GJ63 | denotes | ADH |
T218 | 874-877 | PR:P00334 | denotes | ADH |
T220 | 874-877 | Q24857 | denotes | ADH |
T221 | 874-877 | Q8CQ56 | denotes | ADH |
T222 | 874-877 | Q2FJ31 | denotes | ADH |
T223 | 874-877 | Q2G0G1 | denotes | ADH |
T224 | 874-877 | PR:Q2G0G1 | denotes | ADH |
T226 | 874-877 | Q5HI63 | denotes | ADH |
T227 | 874-877 | Q99W07 | denotes | ADH |
T228 | 874-877 | Q04983 | denotes | ADH |
T209 | 874-877 | CHEBI:34543 | denotes | ADH |
T225 | 874-877 | CHEBI:9937 | denotes | ADH |
T210 | 874-877 | GO:0047636 | denotes | ADH |
T219 | 874-877 | GO:0004022 | denotes | ADH |
T229 | 911-927 | D044584 | denotes | ductal carcinoma |
T230 | 911-927 | D044584 | denotes | ductal carcinoma |
T233 | 980-1002 | D002285 | denotes | intraductal carcinomas |
T234 | 980-1002 | D002285 | denotes | intraductal carcinomas |
T237 | 1286-1289 | P0A388 | denotes | ADH |
T238 | 1286-1289 | PR:P06525 | denotes | ADH |
T239 | 1286-1289 | Q8NXU1 | denotes | ADH |
T240 | 1286-1289 | Q6GBM4 | denotes | ADH |
T241 | 1286-1289 | Q47945 | denotes | ADH |
T242 | 1286-1289 | P0A389 | denotes | ADH |
T243 | 1286-1289 | Q5HRD6 | denotes | ADH |
T244 | 1286-1289 | P28036 | denotes | ADH |
T245 | 1286-1289 | P42327 | denotes | ADH |
T246 | 1286-1289 | PR:P00332 | denotes | ADH |
T249 | 1286-1289 | P81786 | denotes | ADH |
T250 | 1286-1289 | P18278 | denotes | ADH |
T251 | 1286-1289 | Q44002 | denotes | ADH |
T252 | 1286-1289 | Q7A742 | denotes | ADH |
T253 | 1286-1289 | O05542 | denotes | ADH |
T254 | 1286-1289 | Q2YSX0 | denotes | ADH |
T255 | 1286-1289 | Q6GJ63 | denotes | ADH |
T256 | 1286-1289 | PR:P00334 | denotes | ADH |
T258 | 1286-1289 | Q24857 | denotes | ADH |
T259 | 1286-1289 | Q8CQ56 | denotes | ADH |
T260 | 1286-1289 | Q2FJ31 | denotes | ADH |
T261 | 1286-1289 | Q2G0G1 | denotes | ADH |
T262 | 1286-1289 | PR:Q2G0G1 | denotes | ADH |
T264 | 1286-1289 | Q5HI63 | denotes | ADH |
T265 | 1286-1289 | Q99W07 | denotes | ADH |
T266 | 1286-1289 | Q04983 | denotes | ADH |
T247 | 1286-1289 | CHEBI:34543 | denotes | ADH |
T263 | 1286-1289 | CHEBI:9937 | denotes | ADH |
T248 | 1286-1289 | GO:0047636 | denotes | ADH |
T257 | 1286-1289 | GO:0004022 | denotes | ADH |
T268 | 1294-1298 | CVCL_5552 | denotes | DCIS |
T267 | 1294-1298 | D002285 | denotes | DCIS |
T269 | 1294-1298 | D002285 | denotes | DCIS |
T271 | 1337-1341 | CVCL_5552 | denotes | DCIS |
T270 | 1337-1341 | D002285 | denotes | DCIS |
T272 | 1337-1341 | D002285 | denotes | DCIS |
T273 | 1360-1376 | D044584 | denotes | ductal carcinoma |
T274 | 1360-1376 | D044584 | denotes | ductal carcinoma |
UseCases_ArguminSci_Discourse
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 0-86 | DRI_Background | denotes | AgNOR analysis of atypical ductal hyperplasia and intraductal carcinoma of the breast. |
T2 | 92-326 | DRI_Background | denotes | TIVE: To determine the diagnostic and prognostic value of argyrophilic nucleolar organizer regions (AgNORs) in atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS) and microinvasive ductal carcinoma (MDCA) of the breast. |
T3 | 336-440 | DRI_Background | denotes | IGN: Image analysis of histologic sections from biopsies of 46 breast ADH and DCIS and 18 cases of MDCA. |
T4 | 441-557 | DRI_Background | denotes | Determination of morphometric features of cell nuclei and nucleolar organizer regions by using AMBA software system. |
T5 | 558-712 | DRI_Approach | denotes | Data were compared with the estrogen receptor/progesterone receptor (ER/PR) content as well as with the growth fraction, determined immunohistochemically. |
T6 | 722-783 | DRI_Background | denotes | AgNOR number and total AgNOR area increased from ADH to DCIS. |
T7 | 784-853 | DRI_Outcome | denotes | The highest values were recorded in cases of DCIS with microinvasion. |
T8 | 854-959 | DRI_Background | denotes | Differences between ADH and intraductal or microinvasive ductal carcinoma were statistically significant. |
T9 | 960-1092 | DRI_Approach | denotes | Within the group of intraductal carcinomas, the lowest values were measured in the solid type and highest values in the comedo type. |
T10 | 1093-1208 | DRI_Background | denotes | A correlation was found between AgNOR features and growth fraction but not between these features and ER/PR status. |
T11 | 1221-1377 | DRI_Background | denotes | Selected AgNOR features are relevant for differentiation between ADH and DCIS as well as between low and high grade DCIS and microinvasive ductal carcinoma. |
T12 | 1378-1524 | DRI_Background | denotes | Therefore, objective and reproducible data obtained by AgNOR analysis may allow better evaluation of the prognostic significance of these lesions. |
PubMed_Structured_Abstracts
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 98-326 | OBJECTIVE | denotes | To determine the diagnostic and prognostic value of argyrophilic nucleolar organizer regions (AgNORs) in atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS) and microinvasive ductal carcinoma (MDCA) of the breast. |
T2 | 341-712 | METHODS | denotes | Image analysis of histologic sections from biopsies of 46 breast ADH and DCIS and 18 cases of MDCA. Determination of morphometric features of cell nuclei and nucleolar organizer regions by using AMBA software system. Data were compared with the estrogen receptor/progesterone receptor (ER/PR) content as well as with the growth fraction, determined immunohistochemically. |
T3 | 722-1208 | RESULTS | denotes | AgNOR number and total AgNOR area increased from ADH to DCIS. The highest values were recorded in cases of DCIS with microinvasion. Differences between ADH and intraductal or microinvasive ductal carcinoma were statistically significant. Within the group of intraductal carcinomas, the lowest values were measured in the solid type and highest values in the comedo type. A correlation was found between AgNOR features and growth fraction but not between these features and ER/PR status. |
T4 | 1221-1524 | CONCLUSIONS | denotes | Selected AgNOR features are relevant for differentiation between ADH and DCIS as well as between low and high grade DCIS and microinvasive ductal carcinoma. Therefore, objective and reproducible data obtained by AgNOR analysis may allow better evaluation of the prognostic significance of these lesions. |