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PubMed:10837477 JSONTXT

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sentences

Id Subject Object Predicate Lexical cue
T1 0-111 Sentence denotes Apg13p and Vac8p are part of a complex of phosphoproteins that are required for cytoplasm to vacuole targeting.
T2 112-265 Sentence denotes We have been studying protein components that function in the cytoplasm to vacuole targeting (Cvt) pathway and the overlapping process of macroautophagy.
T3 266-372 Sentence denotes The Vac8 and Apg13 proteins are required for the import of aminopeptidase I (API) through the Cvt pathway.
T4 373-502 Sentence denotes We have identified a protein-protein interaction between Vac8p and Apg13p by both two-hybrid and co-immunoprecipitation analysis.
T5 503-630 Sentence denotes Subcellular fractionation of API indicates that Vac8p and Apg13p are involved in the vesicle formation step of the Cvt pathway.
T6 631-779 Sentence denotes Kinetic analysis of the Cvt pathway and autophagy indicates that, although Vac8p is essential for Cvt transport, it is less important for autophagy.
T7 780-956 Sentence denotes In vivo phosphorylation experiments demonstrate that both Vac8p and Apg13p are phosphorylated proteins, and Apg13p phosphorylation is regulated by changing nutrient conditions.
T8 957-1098 Sentence denotes Although Apg13p interacts with the serine/threonine kinase Apg1p, this protein is not required for phosphorylation of either Vac8p or Apg13p.
T9 1099-1206 Sentence denotes Subcellular fractionation experiments indicate that Apg13p and a fraction of Apg1p are membrane-associated.
T10 1207-1320 Sentence denotes Vac8p and Apg13p may be part of a larger protein complex that includes Apg1p and additional interacting proteins.
T11 1321-1485 Sentence denotes Together, these components may form a protein complex that regulates the conversion between Cvt transport and autophagy in response to changing nutrient conditions.

FSU-PRGE

Id Subject Object Predicate Lexical cue
T1 0-6 protein denotes Apg13p
T2 11-16 protein denotes Vac8p
T3 270-274 protein denotes Vac8
T4 279-284 protein denotes Apg13
T5 325-341 protein denotes aminopeptidase I
T6 343-346 protein denotes API
T7 430-435 protein denotes Vac8p
T8 440-446 protein denotes Apg13p
T9 532-535 protein denotes API
T10 551-556 protein denotes Vac8p
T11 561-567 protein denotes Apg13p
T12 706-711 protein denotes Vac8p
T13 838-843 protein denotes Vac8p
T14 848-854 protein denotes Apg13p
T15 888-894 protein denotes Apg13p
T16 966-972 protein denotes Apg13p
T17 992-1015 protein denotes serine/threonine kinase
T18 1016-1021 protein denotes Apg1p
T19 1082-1087 protein denotes Vac8p
T20 1091-1097 protein denotes Apg13p
T21 1151-1157 protein denotes Apg13p
T22 1176-1181 protein denotes Apg1p
T23 1207-1212 protein denotes Vac8p
T24 1217-1223 protein denotes Apg13p
T25 1278-1283 protein denotes Apg1p

LocText

Id Subject Object Predicate Lexical cue
T1 0-6 uniprot:Q06628 denotes Apg13p
T2 11-16 uniprot:P39968 denotes Vac8p
T3 80-89 go:GO:0005737 denotes cytoplasm
T4 93-100 go:GO:0005773 denotes vacuole
T5 174-183 go:GO:0005737 denotes cytoplasm
T6 187-194 go:GO:0005773 denotes vacuole
T7 206-209 go:GO:0033107 denotes Cvt
T8 270-274 uniprot:P39968 denotes Vac8
T9 279-284 uniprot:Q06628 denotes Apg13
T10 360-363 go:GO:0033107 denotes Cvt
T11 430-435 uniprot:P39968 denotes Vac8p
T12 440-446 uniprot:Q06628 denotes Apg13p
T13 551-556 uniprot:P39968 denotes Vac8p
T14 561-567 uniprot:Q06628 denotes Apg13p
T15 618-621 go:GO:0033107 denotes Cvt
T16 655-658 go:GO:0033107 denotes Cvt
T17 706-711 uniprot:P39968 denotes Vac8p
T18 729-732 go:GO:0033107 denotes Cvt
T19 838-843 uniprot:P39968 denotes Vac8p
T20 848-854 uniprot:Q06628 denotes Apg13p
T21 888-894 uniprot:Q06628 denotes Apg13p
T22 966-972 uniprot:Q06628 denotes Apg13p
T23 1016-1021 uniprot:P53104 denotes Apg1p
T24 1082-1087 uniprot:P39968 denotes Vac8p
T25 1091-1097 uniprot:Q06628 denotes Apg13p
T26 1151-1157 uniprot:Q06628 denotes Apg13p
T27 1176-1181 uniprot:P53104 denotes Apg1p
T28 1186-1194 go:GO:0016020 denotes membrane
T29 1207-1212 uniprot:P39968 denotes Vac8p
T30 1217-1223 uniprot:Q06628 denotes Apg13p
T31 1278-1283 uniprot:P53104 denotes Apg1p
T32 1413-1416 go:GO:0033107 denotes Cvt
R1 T1 T4 localizeTo Apg13p,vacuole
R2 T2 T3 localizeTo Vac8p,cytoplasm
R3 T8 T10 localizeTo Vac8,Cvt
R4 T8 T5 localizeTo Vac8,cytoplasm
R5 T8 T6 localizeTo Vac8,vacuole
R6 T8 T7 localizeTo Vac8,Cvt
R7 T9 T10 localizeTo Apg13,Cvt
R8 T9 T7 localizeTo Apg13,Cvt
R9 T9 T6 localizeTo Apg13,vacuole
R10 T9 T5 localizeTo Apg13,cytoplasm
R11 T13 T15 localizeTo Vac8p,Cvt
R12 T14 T15 localizeTo Apg13p,Cvt
R13 T17 T18 localizeTo Vac8p,Cvt
R14 T26 T28 localizeTo Apg13p,membrane
R15 T27 T28 localizeTo Apg1p,membrane
R16 T29 T32 localizeTo Vac8p,Cvt
R17 T30 T32 localizeTo Apg13p,Cvt
R18 T31 T32 localizeTo Apg1p,Cvt

Anatomy-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 80-89 Body_part denotes cytoplasm http://purl.obolibrary.org/obo/GO_0005737
T2 93-100 Body_part denotes vacuole http://purl.obolibrary.org/obo/GO_0005773
T3 174-183 Body_part denotes cytoplasm http://purl.obolibrary.org/obo/GO_0005737
T4 187-194 Body_part denotes vacuole http://purl.obolibrary.org/obo/GO_0005773
T5 588-595 Body_part denotes vesicle http://purl.obolibrary.org/obo/GO_0031982
T6 1186-1194 Body_part denotes membrane http://purl.obolibrary.org/obo/GO_0016020|http://purl.obolibrary.org/obo/UBERON_0000094|http://purl.obolibrary.org/obo/UBERON_0000158