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PubMed:10837462 JSONTXT

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GlyCosmos6-Glycan-Motif-Image

Id Subject Object Predicate Lexical cue image
T1 89-95 Glycan_Motif denotes SSEA-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G25129BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T4 89-93 Glycan_Motif denotes SSEA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI
T5 296-301 Glycan_Motif denotes core3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00035MO
T6 628-637 Glycan_Motif denotes globoside https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO
T7 638-641 Glycan_Motif denotes Gb4 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00061MO
T8 679-682 Glycan_Motif denotes Gb5 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T10 738-744 Glycan_Motif denotes SSEA-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G25129BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T13 738-742 Glycan_Motif denotes SSEA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI
T14 751-757 Glycan_Motif denotes SSEA-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G25129BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T17 751-755 Glycan_Motif denotes SSEA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI
T18 1051-1057 Glycan_Motif denotes SSEA-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G25129BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T21 1051-1055 Glycan_Motif denotes SSEA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI
T22 1229-1235 Glycan_Motif denotes SSEA-3 https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G99053DY|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G25129BT|https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G19298OA
T25 1229-1233 Glycan_Motif denotes SSEA https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G85497PI

Glycosmos6-GlycoEpitope

Id Subject Object Predicate Lexical cue
T1 89-95 http://www.glycoepitope.jp/epitopes/EP0039 denotes SSEA-3
T2 628-637 http://www.glycoepitope.jp/epitopes/EP0073 denotes globoside
T3 738-744 http://www.glycoepitope.jp/epitopes/EP0039 denotes SSEA-3
T4 751-757 http://www.glycoepitope.jp/epitopes/EP0039 denotes SSEA-3
T5 1051-1057 http://www.glycoepitope.jp/epitopes/EP0039 denotes SSEA-3
T6 1229-1235 http://www.glycoepitope.jp/epitopes/EP0039 denotes SSEA-3

sentences

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.
T2 107-350 Sentence denotes We have previously reported the molecular cloning of beta1, 3-galactosyltransferase-V (beta3GalT-V), which catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure.
T3 351-517 Sentence denotes Further characterization indicated that the recombinant beta3GalT-V enzyme expressed in Sf9 insect cells also utilized the glycolipid Lc3Cer as an efficient acceptor.
T4 518-746 Sentence denotes Surprisingly, we also found that beta3GalT-V catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside Gb4, thereby synthesizing the glycolipid Gb5, also known as the stage-specific embryonic antigen-3 (SSEA-3).
T5 747-1018 Sentence denotes The SSEA-3 synthase activity of beta3GalT-V was confirmed in vivo by stable expression of the human beta3GalT-V gene in F9 mouse teratocarcinoma cells, as detected with the monoclonal antibody MC-631 by flow cytometry analysis and immunostaining of extracted glycolipids.
T6 1019-1286 Sentence denotes The biological relation between SSEA-3 formation and beta3GalT-V was further documented by showing that F9 cells treated with the differentiation-inducing agent retinoic acid induced the expression of both the SSEA-3 epitope and the endogenous mouse beta3GalT-V gene.
T7 1287-1458 Sentence denotes This study represents the first example of a glycosyltransferase, which utilizes two kinds of sugar acceptor substrates without requiring any additional modifier molecule.

GlyCosmos6-Glycan-Motif-Structure

Id Subject Object Predicate Lexical cue
T1 89-95 https://glytoucan.org/Structures/Glycans/G19298OA denotes SSEA-3
T2 89-95 https://glytoucan.org/Structures/Glycans/G25129BT denotes SSEA-3
T3 89-95 https://glytoucan.org/Structures/Glycans/G99053DY denotes SSEA-3
T4 89-93 https://glytoucan.org/Structures/Glycans/G85497PI denotes SSEA
T5 628-637 https://glytoucan.org/Structures/Glycans/G00061MO denotes globoside
T6 638-641 https://glytoucan.org/Structures/Glycans/G00061MO denotes Gb4
T7 679-682 https://glytoucan.org/Structures/Glycans/G19298OA denotes Gb5
T8 679-682 https://glytoucan.org/Structures/Glycans/G99053DY denotes Gb5
T9 738-744 https://glytoucan.org/Structures/Glycans/G19298OA denotes SSEA-3
T10 738-744 https://glytoucan.org/Structures/Glycans/G25129BT denotes SSEA-3
T11 738-744 https://glytoucan.org/Structures/Glycans/G99053DY denotes SSEA-3
T12 738-742 https://glytoucan.org/Structures/Glycans/G85497PI denotes SSEA
T13 751-757 https://glytoucan.org/Structures/Glycans/G19298OA denotes SSEA-3
T14 751-757 https://glytoucan.org/Structures/Glycans/G25129BT denotes SSEA-3
T15 751-757 https://glytoucan.org/Structures/Glycans/G99053DY denotes SSEA-3
T16 751-755 https://glytoucan.org/Structures/Glycans/G85497PI denotes SSEA
T17 1051-1057 https://glytoucan.org/Structures/Glycans/G19298OA denotes SSEA-3
T18 1051-1057 https://glytoucan.org/Structures/Glycans/G25129BT denotes SSEA-3
T19 1051-1057 https://glytoucan.org/Structures/Glycans/G99053DY denotes SSEA-3
T20 1051-1055 https://glytoucan.org/Structures/Glycans/G85497PI denotes SSEA
T21 1229-1235 https://glytoucan.org/Structures/Glycans/G19298OA denotes SSEA-3
T22 1229-1235 https://glytoucan.org/Structures/Glycans/G25129BT denotes SSEA-3
T23 1229-1235 https://glytoucan.org/Structures/Glycans/G99053DY denotes SSEA-3
T24 1229-1233 https://glytoucan.org/Structures/Glycans/G85497PI denotes SSEA

NGLY1-deficiency

Id Subject Object Predicate Lexical cue
PD-NGLY1-deficiency-B_T1 247-253 chem:24139 denotes GlcNAc
PD-NGLY1-deficiency-B_T2 318-324 chem:24139 denotes GlcNAc

mondo_disease

Id Subject Object Predicate Lexical cue mondo_id
T1 876-891 Disease denotes teratocarcinoma http://purl.obolibrary.org/obo/MONDO_0002599

Glycan-GlyCosmos

Id Subject Object Predicate Lexical cue image
T1 89-95 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T2 333-339 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 609-615 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 628-637 Glycan denotes globoside https://api.glycosmos.org/wurcs2image/latest/png/binary/G00061MO
T5 638-641 Glycan denotes Gb4 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00061MO
T6 679-682 Glycan denotes Gb5 https://api.glycosmos.org/wurcs2image/latest/png/binary/G99053DY
T7 738-744 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T8 751-757 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T9 1051-1057 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T10 1229-1235 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT

GlyCosmos-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 89-95 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T2 628-637 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes globoside http://www.glycoepitope.jp/epitopes/EP0073
T3 738-744 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T4 751-757 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T5 1051-1057 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T6 1229-1235 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039

GlyCosmos15-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 876-891 Disease denotes teratocarcinoma http://purl.obolibrary.org/obo/MONDO_0002599

GlyCosmos15-NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 841-846 OrganismTaxon denotes human 9606
T2 870-875 OrganismTaxon denotes mouse 10088|10090
T4 1263-1268 OrganismTaxon denotes mouse 10088|10090

sentences

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.
T2 107-350 Sentence denotes We have previously reported the molecular cloning of beta1, 3-galactosyltransferase-V (beta3GalT-V), which catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure.
T3 351-517 Sentence denotes Further characterization indicated that the recombinant beta3GalT-V enzyme expressed in Sf9 insect cells also utilized the glycolipid Lc3Cer as an efficient acceptor.
T4 518-746 Sentence denotes Surprisingly, we also found that beta3GalT-V catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside Gb4, thereby synthesizing the glycolipid Gb5, also known as the stage-specific embryonic antigen-3 (SSEA-3).
T5 747-1018 Sentence denotes The SSEA-3 synthase activity of beta3GalT-V was confirmed in vivo by stable expression of the human beta3GalT-V gene in F9 mouse teratocarcinoma cells, as detected with the monoclonal antibody MC-631 by flow cytometry analysis and immunostaining of extracted glycolipids.
T6 1019-1286 Sentence denotes The biological relation between SSEA-3 formation and beta3GalT-V was further documented by showing that F9 cells treated with the differentiation-inducing agent retinoic acid induced the expression of both the SSEA-3 epitope and the endogenous mouse beta3GalT-V gene.
T7 1287-1458 Sentence denotes This study represents the first example of a glycosyltransferase, which utilizes two kinds of sugar acceptor substrates without requiring any additional modifier molecule.

GlyCosmos15-Sentences

Id Subject Object Predicate Lexical cue
T1 0-106 Sentence denotes The beta 1,3-galactosyltransferase beta 3GalT-V is a stage-specific embryonic antigen-3 (SSEA-3) synthase.
T2 107-350 Sentence denotes We have previously reported the molecular cloning of beta1, 3-galactosyltransferase-V (beta3GalT-V), which catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure.
T3 351-517 Sentence denotes Further characterization indicated that the recombinant beta3GalT-V enzyme expressed in Sf9 insect cells also utilized the glycolipid Lc3Cer as an efficient acceptor.
T4 518-746 Sentence denotes Surprisingly, we also found that beta3GalT-V catalyzes the transfer of Gal to the terminal GalNAc unit of the globoside Gb4, thereby synthesizing the glycolipid Gb5, also known as the stage-specific embryonic antigen-3 (SSEA-3).
T5 747-1018 Sentence denotes The SSEA-3 synthase activity of beta3GalT-V was confirmed in vivo by stable expression of the human beta3GalT-V gene in F9 mouse teratocarcinoma cells, as detected with the monoclonal antibody MC-631 by flow cytometry analysis and immunostaining of extracted glycolipids.
T6 1019-1286 Sentence denotes The biological relation between SSEA-3 formation and beta3GalT-V was further documented by showing that F9 cells treated with the differentiation-inducing agent retinoic acid induced the expression of both the SSEA-3 epitope and the endogenous mouse beta3GalT-V gene.
T7 1287-1458 Sentence denotes This study represents the first example of a glycosyltransferase, which utilizes two kinds of sugar acceptor substrates without requiring any additional modifier molecule.

GlyCosmos15-Glycan

Id Subject Object Predicate Lexical cue image
T1 89-95 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T2 333-339 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T3 609-615 Glycan denotes GalNAc https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL
T4 628-637 Glycan denotes globoside https://api.glycosmos.org/wurcs2image/latest/png/binary/G00061MO
T5 638-641 Glycan denotes Gb4 https://api.glycosmos.org/wurcs2image/latest/png/binary/G00061MO
T6 679-682 Glycan denotes Gb5 https://api.glycosmos.org/wurcs2image/latest/png/binary/G99053DY
T7 738-744 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T8 751-757 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T9 1051-1057 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT
T10 1229-1235 Glycan denotes SSEA-3 https://api.glycosmos.org/wurcs2image/latest/png/binary/G25129BT

GlyCosmos15-GlycoEpitope

Id Subject Object Predicate Lexical cue glycoepitope_id
T1 89-95 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T2 628-637 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes globoside http://www.glycoepitope.jp/epitopes/EP0073
T3 738-744 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T4 751-757 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T5 1051-1057 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039
T6 1229-1235 http://purl.jp/bio/12/glyco/glycan#Glycan_epitope denotes SSEA-3 http://www.glycoepitope.jp/epitopes/EP0039

NCBITAXON

Id Subject Object Predicate Lexical cue db_id
T1 841-846 OrganismTaxon denotes human 9606
T2 870-875 OrganismTaxon denotes mouse 10088|10090
T4 1263-1268 OrganismTaxon denotes mouse 10088|10090