> top > docs > PubMed:10820269 > annotations

PubMed:10820269 JSONTXT

Annnotations TAB JSON ListView MergeView

c_corpus

Id Subject Object Predicate Lexical cue
T1 0-8 PR:000002327 denotes Secreted
T3 13-21 GO:0016020 denotes membrane
T2 13-21 UBERON:0000094 denotes membrane
T4 13-21 UBERON:0000158 denotes membrane
T5 13-58 D053504 denotes membrane-associated matrix metalloproteinases
T6 33-39 UBERON:0027368 denotes matrix
T9 62-66 P04351 denotes IL-2
T10 62-66 Q07885 denotes IL-2
T11 62-66 Q865X2 denotes IL-2
T12 62-66 P19114 denotes IL-2
T13 62-66 PR:P04351 denotes IL-2
T14 62-66 Q7JFM2 denotes IL-2
T15 62-66 Q08081 denotes IL-2
T16 62-66 Q95KP3 denotes IL-2
T17 62-66 PR:000001379 denotes IL-2
T18 62-66 Q5MBA8 denotes IL-2
T19 62-66 P60569 denotes IL-2
T20 62-66 O77620 denotes IL-2
T21 62-66 PR:P17108 denotes IL-2
T22 62-66 Q4U313 denotes IL-2
T23 62-66 P37997 denotes IL-2
T24 62-66 Q9XS38 denotes IL-2
T26 62-66 Q865Y1 denotes IL-2
T27 62-66 Q9XT83 denotes IL-2
T28 62-66 O97513 denotes IL-2
T29 62-66 Q9XT84 denotes IL-2
T30 62-66 Q1WM29 denotes IL-2
T31 62-66 Q25BC3 denotes IL-2
T32 62-66 Q2PE47 denotes IL-2
T33 62-66 P68290 denotes IL-2
T34 62-66 Q7JFM4 denotes IL-2
T35 62-66 P68291 denotes IL-2
T36 62-66 Q29416 denotes IL-2
T37 62-66 P51747 denotes IL-2
T38 62-66 Q7JFM5 denotes IL-2
T39 62-66 Q8MKH2 denotes IL-2
T40 62-66 P26891 denotes IL-2
T42 62-66 P05016 denotes IL-2
T44 62-66 Q2PE78 denotes IL-2
T45 62-66 P60568 denotes IL-2
T46 62-66 Q7JFM3 denotes IL-2
T47 62-66 Q08867 denotes IL-2
T48 62-66 Q29615 denotes IL-2
T49 62-66 P17108 denotes IL-2
T50 62-66 P36835 denotes IL-2
T51 62-66 Q5PXD0 denotes IL-2
T52 62-66 PR:P60568 denotes IL-2
T53 62-66 P46649 denotes IL-2
T54 62-66 O62641 denotes IL-2
T41 62-66 D007376 denotes IL-2
T43 62-66 D007376 denotes IL-2
T25 62-66 GO:0005134 denotes IL-2
T55 96-106 CHEBI:35222 denotes inhibitors
T56 143-146 10116 denotes rat
T60 143-146 D051381 denotes rat
T57 143-146 PR:P63003-1 denotes rat
T58 143-146 PR:Q2G0B1 denotes rat
T59 143-146 PR:Q8VHJ4 denotes rat
T61 147-151 P04351 denotes IL-2
T62 147-151 Q07885 denotes IL-2
T63 147-151 Q865X2 denotes IL-2
T64 147-151 P19114 denotes IL-2
T65 147-151 PR:P04351 denotes IL-2
T66 147-151 Q7JFM2 denotes IL-2
T67 147-151 Q08081 denotes IL-2
T68 147-151 Q95KP3 denotes IL-2
T69 147-151 PR:000001379 denotes IL-2
T70 147-151 Q5MBA8 denotes IL-2
T71 147-151 P60569 denotes IL-2
T72 147-151 O77620 denotes IL-2
T73 147-151 PR:P17108 denotes IL-2
T74 147-151 Q4U313 denotes IL-2
T75 147-151 P37997 denotes IL-2
T76 147-151 Q9XS38 denotes IL-2
T78 147-151 Q865Y1 denotes IL-2
T79 147-151 Q9XT83 denotes IL-2
T80 147-151 O97513 denotes IL-2
T81 147-151 Q9XT84 denotes IL-2
T82 147-151 Q1WM29 denotes IL-2
T83 147-151 Q25BC3 denotes IL-2
T84 147-151 Q2PE47 denotes IL-2
T85 147-151 P68290 denotes IL-2
T86 147-151 Q7JFM4 denotes IL-2
T87 147-151 P68291 denotes IL-2
T88 147-151 Q29416 denotes IL-2
T89 147-151 P51747 denotes IL-2
T90 147-151 Q7JFM5 denotes IL-2
T91 147-151 Q8MKH2 denotes IL-2
T92 147-151 P26891 denotes IL-2
T94 147-151 P05016 denotes IL-2
T96 147-151 Q2PE78 denotes IL-2
T97 147-151 P60568 denotes IL-2
T98 147-151 Q7JFM3 denotes IL-2
T99 147-151 Q08867 denotes IL-2
T100 147-151 Q29615 denotes IL-2
T101 147-151 P17108 denotes IL-2
T102 147-151 P36835 denotes IL-2
T103 147-151 Q5PXD0 denotes IL-2
T104 147-151 PR:P60568 denotes IL-2
T105 147-151 P46649 denotes IL-2
T106 147-151 O62641 denotes IL-2
T93 147-151 D007376 denotes IL-2
T95 147-151 D007376 denotes IL-2
T77 147-151 GO:0005134 denotes IL-2
T107 186-192 UBERON:0027368 denotes matrix
T108 186-212 Q9GLE5 denotes matrix metalloproteinase-2
T109 186-212 P08253 denotes matrix metalloproteinase-2
T110 186-212 Q8MPP3 denotes matrix metalloproteinase-2
T111 186-212 Q90611 denotes matrix metalloproteinase-2
T113 186-212 PR:000010479 denotes matrix metalloproteinase-2
T114 186-212 P33436 denotes matrix metalloproteinase-2
T115 186-212 P33434 denotes matrix metalloproteinase-2
T116 186-212 P50757 denotes matrix metalloproteinase-2
T112 186-212 D020778 denotes matrix metalloproteinase-2
T118 211-217 PR:O04529 denotes 2 (MMP
T119 214-217 CHEBI:340824 denotes MMP
T122 214-217 CHEBI:59761 denotes MMP
T123 214-219 PR:P08253 denotes MMP-2
T124 214-219 Q9GLE5 denotes MMP-2
T125 214-219 P08253 denotes MMP-2
T126 214-219 Q90611 denotes MMP-2
T128 214-219 PR:Q8MPP3 denotes MMP-2
T129 214-219 P33436 denotes MMP-2
T130 214-219 PR:Q90611 denotes MMP-2
T131 214-219 PR:P33436 denotes MMP-2
T132 214-219 PR:000010479 denotes MMP-2
T133 214-219 PR:P33434 denotes MMP-2
T134 214-219 P33434 denotes MMP-2
T135 214-219 P50757 denotes MMP-2
T127 214-219 GO:0004228 denotes MMP-2
T136 225-228 CHEBI:340824 denotes MMP
T139 225-228 CHEBI:59761 denotes MMP
T140 225-230 PR:P50282 denotes MMP-9
T141 225-230 PR:P14780 denotes MMP-9
T142 225-230 P14780 denotes MMP-9
T143 225-230 PR:P41245 denotes MMP-9
T144 225-230 P41246 denotes MMP-9
T145 225-230 P41245 denotes MMP-9
T146 225-230 PR:P52176 denotes MMP-9
T147 225-230 P50282 denotes MMP-9
T149 225-230 PR:000010491 denotes MMP-9
T150 225-230 P52176 denotes MMP-9
T151 225-230 O18733 denotes MMP-9
T148 225-230 GO:0004229 denotes MMP-9
T152 259-264 10090 denotes mouse
T153 259-264 D051379 denotes mouse
T155 267-274 UBERON:3010310 denotes NK cell
T154 267-274 CL:0000623 denotes NK cell
T156 283-287 D020782 denotes MMPs
T157 302-306 D020782 denotes MMPs
T158 327-330 Q41249 denotes PCR
T159 327-330 O66148 denotes PCR
T160 327-330 Q59987 denotes PCR
T161 327-330 Q01289 denotes PCR
T162 327-330 O80333 denotes PCR
T163 327-330 P15904 denotes PCR
T164 327-330 Q9SDT1 denotes PCR
T165 327-330 Q39617 denotes PCR
T166 345-349 SO:0000756 denotes cDNA
T167 345-349 D018076 denotes cDNA
T168 353-358 10090 denotes mouse
T169 353-358 D051379 denotes mouse
T172 379-383 SO:0000234 denotes mRNA
T170 379-383 D012333 denotes mRNA
T171 379-383 CHEBI:33699 denotes mRNA
T173 388-391 CHEBI:340824 denotes MMP
T176 388-391 CHEBI:59761 denotes MMP
T177 388-393 PR:P08253 denotes MMP-2
T178 388-393 Q9GLE5 denotes MMP-2
T179 388-393 P08253 denotes MMP-2
T180 388-393 Q90611 denotes MMP-2
T182 388-393 PR:Q8MPP3 denotes MMP-2
T183 388-393 P33436 denotes MMP-2
T184 388-393 PR:Q90611 denotes MMP-2
T185 388-393 PR:P33436 denotes MMP-2
T186 388-393 PR:000010479 denotes MMP-2
T187 388-393 PR:P33434 denotes MMP-2
T188 388-393 P33434 denotes MMP-2
T189 388-393 P50757 denotes MMP-2
T181 388-393 GO:0004228 denotes MMP-2
T190 392-398 PR:O04529 denotes 2, MMP
T191 395-398 CHEBI:340824 denotes MMP
T194 395-398 CHEBI:59761 denotes MMP
T195 395-400 PR:P50282 denotes MMP-9
T196 395-400 PR:P14780 denotes MMP-9
T197 395-400 P14780 denotes MMP-9
T198 395-400 PR:P41245 denotes MMP-9
T199 395-400 P41246 denotes MMP-9
T200 395-400 P41245 denotes MMP-9
T201 395-400 PR:P52176 denotes MMP-9
T202 395-400 P50282 denotes MMP-9
T204 395-400 PR:000010491 denotes MMP-9
T205 395-400 P52176 denotes MMP-9
T206 395-400 O18733 denotes MMP-9
T203 395-400 GO:0004229 denotes MMP-9
T207 402-405 CHEBI:340824 denotes MMP
T210 402-405 CHEBI:59761 denotes MMP
T211 402-408 Q499S5 denotes MMP-11
T212 402-408 Q11005 denotes MMP-11
T213 402-408 PR:P24347 denotes MMP-11
T214 402-408 P24347 denotes MMP-11
T215 402-408 PR:Q499S5 denotes MMP-11
T216 402-408 PR:000010471 denotes MMP-11
T217 402-408 PR:Q02853 denotes MMP-11
T219 402-408 Q02853 denotes MMP-11
T218 402-408 GO:0004249 denotes MMP-11
T220 410-413 CHEBI:340824 denotes MMP
T223 410-413 CHEBI:59761 denotes MMP
T225 410-416 P45452 denotes MMP-13
T226 410-416 PR:000010473 denotes MMP-13
T227 410-416 O77656 denotes MMP-13
T228 410-416 Q10835 denotes MMP-13
T229 410-416 PR:P33435 denotes MMP-13
T230 410-416 O18927 denotes MMP-13
T231 410-416 PR:P23097 denotes MMP-13
T232 410-416 P33435 denotes MMP-13
T233 410-416 PR:P45452 denotes MMP-13
T234 410-416 PR:O77656 denotes MMP-13
T235 410-416 P23097 denotes MMP-13
T236 410-416 O62806 denotes MMP-13
T224 410-416 GO:0030404 denotes MMP-13
T259 418-421 CVCL_2501 denotes MT1
T244 418-421 GO:0047152 denotes MT1
T253 418-421 GO:0043791 denotes MT1
T262 418-421 GO:0043834 denotes MT1
T278 418-425 Q9XT90 denotes MT1-MMP
T279 418-425 P50281 denotes MT1-MMP
T280 418-425 Q9GLE4 denotes MT1-MMP
T281 418-425 PR:000010474 denotes MT1-MMP
T282 418-425 Q10739 denotes MT1-MMP
T283 418-425 Q95220 denotes MT1-MMP
T285 418-425 P53690 denotes MT1-MMP
T284 418-425 D053511 denotes MT1-MMP
T288 422-425 GO:0004235 denotes MMP
T318 427-430 CVCL_2631 denotes MT2
T313 427-430 GO:0043851 denotes MT2
T325 427-434 O54732 denotes MT2-MMP
T326 427-434 P51511 denotes MT2-MMP
T327 427-434 PR:000010475 denotes MT2-MMP
T324 427-434 D053517 denotes MT2-MMP
T330 431-434 GO:0004235 denotes MMP
T337 436-442 P81546 denotes TIMP-1
T338 436-442 O02722 denotes TIMP-1
T339 436-442 P49061 denotes TIMP-1
T340 436-442 P50122 denotes TIMP-1
T341 436-442 P20614 denotes TIMP-1
T342 436-442 P12032 denotes TIMP-1
T343 436-442 P35624 denotes TIMP-1
T344 436-442 P20414 denotes TIMP-1
T345 436-442 Q95KL9 denotes TIMP-1
T346 436-442 Q5RC60 denotes TIMP-1
T347 436-442 PR:P30120 denotes TIMP-1
T348 436-442 P30120 denotes TIMP-1
T349 436-442 PR:000016352 denotes TIMP-1
T351 436-442 PR:P12032 denotes TIMP-1
T352 436-442 PR:P01033 denotes TIMP-1
T353 436-442 P01033 denotes TIMP-1
T350 436-442 D019715 denotes TIMP-1
T358 448-454 PR:P16035 denotes TIMP-2
T359 448-454 PR:000016353 denotes TIMP-2
T360 448-454 O42146 denotes TIMP-2
T361 448-454 Q9TRZ7 denotes TIMP-2
T362 448-454 Q9TTY1 denotes TIMP-2
T363 448-454 Q60453 denotes TIMP-2
T364 448-454 P16035 denotes TIMP-2
T366 448-454 P25785 denotes TIMP-2
T367 448-454 P16368 denotes TIMP-2
T368 448-454 O77717 denotes TIMP-2
T369 448-454 PR:P25785 denotes TIMP-2
T370 448-454 P30121 denotes TIMP-2
T371 448-454 Q9WUC6 denotes TIMP-2
T372 448-454 PR:P30121 denotes TIMP-2
T373 448-454 PR:O42146 denotes TIMP-2
T365 448-454 D019716 denotes TIMP-2
T374 456-459 CHEBI:340824 denotes MMP
T377 456-459 CHEBI:59761 denotes MMP
T378 456-461 PR:P08253 denotes MMP-2
T379 456-461 Q9GLE5 denotes MMP-2
T380 456-461 P08253 denotes MMP-2
T381 456-461 Q90611 denotes MMP-2
T383 456-461 PR:Q8MPP3 denotes MMP-2
T384 456-461 P33436 denotes MMP-2
T385 456-461 PR:Q90611 denotes MMP-2
T386 456-461 PR:P33436 denotes MMP-2
T387 456-461 PR:000010479 denotes MMP-2
T388 456-461 PR:P33434 denotes MMP-2
T389 456-461 P33434 denotes MMP-2
T390 456-461 P50757 denotes MMP-2
T382 456-461 GO:0004228 denotes MMP-2
T391 466-469 CHEBI:340824 denotes MMP
T394 466-469 CHEBI:59761 denotes MMP
T395 466-471 PR:P50282 denotes MMP-9
T396 466-471 PR:P14780 denotes MMP-9
T397 466-471 P14780 denotes MMP-9
T398 466-471 PR:P41245 denotes MMP-9
T399 466-471 P41246 denotes MMP-9
T400 466-471 P41245 denotes MMP-9
T401 466-471 PR:P52176 denotes MMP-9
T402 466-471 P50282 denotes MMP-9
T404 466-471 PR:000010491 denotes MMP-9
T405 466-471 P52176 denotes MMP-9
T406 466-471 O18733 denotes MMP-9
T403 466-471 GO:0004229 denotes MMP-9
T407 500-507 4716 denotes gelatin
T408 500-507 D005780 denotes gelatin
T409 500-507 CHEBI:5291 denotes gelatin
T410 567-571 D020782 denotes MMPs
T411 657-660 Q41249 denotes PCR
T412 657-660 O66148 denotes PCR
T413 657-660 Q59987 denotes PCR
T414 657-660 Q01289 denotes PCR
T415 657-660 O80333 denotes PCR
T416 657-660 P15904 denotes PCR
T417 657-660 Q9SDT1 denotes PCR
T418 657-660 Q39617 denotes PCR
T423 680-686 P81546 denotes TIMP-1
T424 680-686 O02722 denotes TIMP-1
T425 680-686 P49061 denotes TIMP-1
T426 680-686 P50122 denotes TIMP-1
T427 680-686 P20614 denotes TIMP-1
T428 680-686 P12032 denotes TIMP-1
T429 680-686 P35624 denotes TIMP-1
T430 680-686 P20414 denotes TIMP-1
T431 680-686 Q95KL9 denotes TIMP-1
T432 680-686 Q5RC60 denotes TIMP-1
T433 680-686 PR:P30120 denotes TIMP-1
T434 680-686 P30120 denotes TIMP-1
T435 680-686 PR:000016352 denotes TIMP-1
T437 680-686 PR:P12032 denotes TIMP-1
T438 680-686 PR:P01033 denotes TIMP-1
T439 680-686 P01033 denotes TIMP-1
T436 680-686 D019715 denotes TIMP-1
T443 716-730 Q9QPN4 denotes 29-kDa protein
T444 716-730 P69472 denotes 29-kDa protein
T445 716-730 P09504 denotes 29-kDa protein
T446 716-730 P69473 denotes 29-kDa protein
T447 716-730 P05074 denotes 29-kDa protein
T448 716-730 O07950 denotes 29-kDa protein
T449 716-730 P50170 denotes 29-kDa protein
T450 723-730 GO:0003675 denotes protein
T454 723-730 SO:0000104 denotes protein
T451 723-730 CHEBI:36080 denotes protein
T452 723-730 CHEBI:11122 denotes protein
T459 771-777 PR:P16035 denotes TIMP-2
T460 771-777 PR:000016353 denotes TIMP-2
T461 771-777 O42146 denotes TIMP-2
T462 771-777 Q9TRZ7 denotes TIMP-2
T463 771-777 Q9TTY1 denotes TIMP-2
T464 771-777 Q60453 denotes TIMP-2
T465 771-777 P16035 denotes TIMP-2
T467 771-777 P25785 denotes TIMP-2
T468 771-777 P16368 denotes TIMP-2
T469 771-777 O77717 denotes TIMP-2
T470 771-777 PR:P25785 denotes TIMP-2
T471 771-777 P30121 denotes TIMP-2
T472 771-777 Q9WUC6 denotes TIMP-2
T473 771-777 PR:P30121 denotes TIMP-2
T474 771-777 PR:O42146 denotes TIMP-2
T466 771-777 D019716 denotes TIMP-2
T478 778-785 PR:000000001 denotes protein
T475 778-785 GO:0003675 denotes protein
T479 778-785 SO:0000104 denotes protein
T476 778-785 CHEBI:36080 denotes protein
T477 778-785 CHEBI:11122 denotes protein
T483 825-839 Q9QPN4 denotes 29-kDa protein
T484 825-839 P69472 denotes 29-kDa protein
T485 825-839 P09504 denotes 29-kDa protein
T486 825-839 P69473 denotes 29-kDa protein
T487 825-839 P05074 denotes 29-kDa protein
T488 825-839 O07950 denotes 29-kDa protein
T489 825-839 P50170 denotes 29-kDa protein
T490 832-839 GO:0003675 denotes protein
T494 832-839 SO:0000104 denotes protein
T491 832-839 CHEBI:36080 denotes protein
T492 832-839 CHEBI:11122 denotes protein
T495 925-930 10090 denotes mouse
T496 925-930 D051379 denotes mouse
T497 935-940 D006801 denotes human
T498 975-979 D020782 denotes MMPs
T499 983-988 C080985 denotes BB-94
T500 983-988 C080985 denotes BB-94
T501 1002-1011 CHEBI:35222 denotes inhibitor
T502 1015-1018 CHEBI:340824 denotes MMP
T505 1015-1018 CHEBI:59761 denotes MMP
T504 1015-1018 PR:O04529 denotes MMP
T503 1015-1018 GO:0004235 denotes MMP
T506 1059-1064 10090 denotes mouse
T507 1059-1064 D051379 denotes mouse
T508 1095-1103 C059485 denotes Matrigel
T510 1113-1130 UBERON:0005769 denotes basement membrane
T509 1113-1130 GO:0005604 denotes basement membrane
T514 1214-1218 D020782 denotes MMPs
T515 1260-1271 GO:0009056 denotes degradation
T517 1283-1303 GO:0031012 denotes extracellular matrix
T518 1297-1303 UBERON:0027368 denotes matrix
T519 1304-1313 CHEBI:25367 denotes molecules
T520 1339-1352 UBERON:0004537 denotes blood vessels
T521 1382-1392 D009362 denotes metastases
T522 1382-1392 D009362 denotes metastases

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 1375-1381 HP_0002664 denotes cancer

UseCases_ArguminSci_Discourse

Id Subject Object Predicate Lexical cue
T1 0-107 DRI_Background denotes Secreted and membrane-associated matrix metalloproteinases of IL-2-activated NK cells and their inhibitors.
T2 108-231 DRI_Approach denotes We have previously documented that rat IL-2-activated NK (A-NK) cells produce matrix metalloproteinase-2 (MMP-2) and MMP-9.
T3 232-264 DRI_Approach denotes In this study, we describe mouse
T4 265-282 Token_Label.OUTSIDE denotes A-NK cell-derived
T5 283-323 DRI_Approach denotes MMPs, including MT-MMPs, and also TIMPs.
T6 324-455 DRI_Approach denotes RT-PCR analysis from cDNA of mouse A-NK cells revealed mRNA for MMP-2, MMP-9, MMP-11, MMP-13, MT1-MMP, MT2-MMP, TIMP-1, and TIMP-2.
T7 456-519 DRI_Background denotes MMP-2 and MMP-9 expression was confirmed by gelatin zymography.
T8 520-679 DRI_Outcome denotes Moreover, we report for the first time that MT-MMPs are expressed by NK cells, i.e., large granular lymphocytes as determined by both RT-PCR and Western blots.
T9 680-748 DRI_Background denotes TIMP-1 expression was detected as a 29-kDa protein in Western blots.
T10 749-947 DRI_Background denotes It is intriguing that TIMP-2 protein from A-NK cells was also detected as a 29-kDa protein, which is clearly different from the previously reported molecular mass of 21 kDa in mouse and human cells.
T11 948-1131 DRI_Approach denotes In addition, inhibition of MMPs by BB-94, a selective inhibitor of MMP, significantly inhibited the ability of mouse A-NK cells to migrate through Matrigel, a model basement membrane.
T12 1132-1427 DRI_Approach denotes Taken together, these findings suggest that A-NK cells may therefore use multiple MMPs in various cellular functions, including degradation of various extracellular matrix molecules as they extravasate from blood vessels and accumulate within cancer metastases following their adoptive transfer.