PubMed:10818104
Annnotations
GlyCosmos6-Glycan-Motif-Image
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 42-53 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T2 | 318-329 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T3 | 578-589 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T4 | 674-684 | Glycan_Motif | denotes | hyaluronan | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00017MO |
| T5 | 908-919 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T6 | 1255-1266 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T7 | 1307-1317 | Glycan_Motif | denotes | hyaluronan | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00017MO |
| T8 | 1424-1435 | Glycan_Motif | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G43702JT |
| T9 | 1515-1525 | Glycan_Motif | denotes | hyaluronan | https://api.glycosmos.org/wurcs2image/0.10.0/png/binary/G00017MO |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-97 | Sentence | denotes | Identification and molecular cloning of a chondroitin synthase from Pasteurella multocida type F. |
| T2 | 98-246 | Sentence | denotes | Pasteurella multocida Type F, the minor fowl cholera pathogen, produces an extracellular polysaccharide capsule that is a putative virulence factor. |
| T3 | 247-339 | Sentence | denotes | It was reported that the capsule was removed by treating microbes with chondroitin AC lyase. |
| T4 | 340-436 | Sentence | denotes | We found by acid hydrolysis that the polysaccharide contained galactosamine and glucuronic acid. |
| T5 | 437-533 | Sentence | denotes | We molecularly cloned a Type F polysaccharide synthase and characterized its enzymatic activity. |
| T6 | 534-727 | Sentence | denotes | The 965-residue enzyme, called P. multocida chondroitin synthase (pmCS), is 87% identical at the nucleotide and the amino acid level to the hyaluronan synthase, pmHAS, from P. multocida Type A. |
| T7 | 728-955 | Sentence | denotes | A recombinant Escherichia coli-derived truncated, soluble version of pmCS (residues 1-704) was shown to catalyze the repetitive addition of sugars from UDP-GalNAc and UDP-GlcUA to chondroitin oligosaccharide acceptors in vitro. |
| T8 | 956-1057 | Sentence | denotes | Other structurally related sugar nucleotide precursors did not substitute in the elongation reaction. |
| T9 | 1058-1183 | Sentence | denotes | Polymer molecules composed of approximately 10(3) sugar residues were produced, as measured by gel filtration chromatography. |
| T10 | 1184-1324 | Sentence | denotes | The polysaccharide synthesized in vitro was sensitive to the action of chondroitin AC lyase but resistant to the action of hyaluronan lyase. |
| T11 | 1325-1494 | Sentence | denotes | This is the first report identifying a glycosyltransferase that forms a polysaccharide composed of chondroitin disaccharide repeats, [beta(1,4)GlcUA-beta(1,3)GalNAc](n). |
| T12 | 1495-1611 | Sentence | denotes | In analogy to known hyaluronan synthases, a single polypeptide species, pmCS, possesses both transferase activities. |
GlyCosmos6-Glycan-Motif-Structure
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 42-53 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T2 | 318-329 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T3 | 578-589 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T4 | 674-684 | https://glytoucan.org/Structures/Glycans/G00017MO | denotes | hyaluronan |
| T5 | 908-919 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T6 | 1255-1266 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T7 | 1307-1317 | https://glytoucan.org/Structures/Glycans/G00017MO | denotes | hyaluronan |
| T8 | 1424-1435 | https://glytoucan.org/Structures/Glycans/G43702JT | denotes | chondroitin |
| T9 | 1515-1525 | https://glytoucan.org/Structures/Glycans/G00017MO | denotes | hyaluronan |
Glycosmos6-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 42-53 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T2 | 318-329 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T3 | 578-589 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T4 | 908-919 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T5 | 1255-1266 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
| T6 | 1424-1435 | http://www.glycoepitope.jp/epitopes/EP0081 | denotes | chondroitin |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 143-150 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
Glycan-GlyCosmos
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 42-53 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 318-329 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 578-589 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 884-890 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T5 | 908-919 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T6 | 1255-1266 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T7 | 1424-1435 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T8 | 1483-1489 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 143-150 | Disease | denotes | cholera | http://purl.obolibrary.org/obo/MONDO_0015766 |
GlyCosmos15-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 68-89 | OrganismTaxon | denotes | Pasteurella multocida | 747 |
| T2 | 98-119 | OrganismTaxon | denotes | Pasteurella multocida | 747 |
| T3 | 742-758 | OrganismTaxon | denotes | Escherichia coli | 562 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 173-186 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-97 | Sentence | denotes | Identification and molecular cloning of a chondroitin synthase from Pasteurella multocida type F. |
| T2 | 98-246 | Sentence | denotes | Pasteurella multocida Type F, the minor fowl cholera pathogen, produces an extracellular polysaccharide capsule that is a putative virulence factor. |
| T3 | 247-339 | Sentence | denotes | It was reported that the capsule was removed by treating microbes with chondroitin AC lyase. |
| T4 | 340-436 | Sentence | denotes | We found by acid hydrolysis that the polysaccharide contained galactosamine and glucuronic acid. |
| T5 | 437-533 | Sentence | denotes | We molecularly cloned a Type F polysaccharide synthase and characterized its enzymatic activity. |
| T6 | 534-727 | Sentence | denotes | The 965-residue enzyme, called P. multocida chondroitin synthase (pmCS), is 87% identical at the nucleotide and the amino acid level to the hyaluronan synthase, pmHAS, from P. multocida Type A. |
| T7 | 728-955 | Sentence | denotes | A recombinant Escherichia coli-derived truncated, soluble version of pmCS (residues 1-704) was shown to catalyze the repetitive addition of sugars from UDP-GalNAc and UDP-GlcUA to chondroitin oligosaccharide acceptors in vitro. |
| T8 | 956-1057 | Sentence | denotes | Other structurally related sugar nucleotide precursors did not substitute in the elongation reaction. |
| T9 | 1058-1183 | Sentence | denotes | Polymer molecules composed of approximately 10(3) sugar residues were produced, as measured by gel filtration chromatography. |
| T10 | 1184-1324 | Sentence | denotes | The polysaccharide synthesized in vitro was sensitive to the action of chondroitin AC lyase but resistant to the action of hyaluronan lyase. |
| T11 | 1325-1494 | Sentence | denotes | This is the first report identifying a glycosyltransferase that forms a polysaccharide composed of chondroitin disaccharide repeats, [beta(1,4)GlcUA-beta(1,3)GalNAc](n). |
| T12 | 1495-1611 | Sentence | denotes | In analogy to known hyaluronan synthases, a single polypeptide species, pmCS, possesses both transferase activities. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-97 | Sentence | denotes | Identification and molecular cloning of a chondroitin synthase from Pasteurella multocida type F. |
| T2 | 98-246 | Sentence | denotes | Pasteurella multocida Type F, the minor fowl cholera pathogen, produces an extracellular polysaccharide capsule that is a putative virulence factor. |
| T3 | 247-339 | Sentence | denotes | It was reported that the capsule was removed by treating microbes with chondroitin AC lyase. |
| T4 | 340-436 | Sentence | denotes | We found by acid hydrolysis that the polysaccharide contained galactosamine and glucuronic acid. |
| T5 | 437-533 | Sentence | denotes | We molecularly cloned a Type F polysaccharide synthase and characterized its enzymatic activity. |
| T6 | 534-955 | Sentence | denotes | The 965-residue enzyme, called P. multocida chondroitin synthase (pmCS), is 87% identical at the nucleotide and the amino acid level to the hyaluronan synthase, pmHAS, from P. multocida Type A. A recombinant Escherichia coli-derived truncated, soluble version of pmCS (residues 1-704) was shown to catalyze the repetitive addition of sugars from UDP-GalNAc and UDP-GlcUA to chondroitin oligosaccharide acceptors in vitro. |
| T7 | 956-1057 | Sentence | denotes | Other structurally related sugar nucleotide precursors did not substitute in the elongation reaction. |
| T8 | 1058-1183 | Sentence | denotes | Polymer molecules composed of approximately 10(3) sugar residues were produced, as measured by gel filtration chromatography. |
| T9 | 1184-1324 | Sentence | denotes | The polysaccharide synthesized in vitro was sensitive to the action of chondroitin AC lyase but resistant to the action of hyaluronan lyase. |
| T10 | 1325-1494 | Sentence | denotes | This is the first report identifying a glycosyltransferase that forms a polysaccharide composed of chondroitin disaccharide repeats, [beta(1,4)GlcUA-beta(1,3)GalNAc](n). |
| T11 | 1495-1611 | Sentence | denotes | In analogy to known hyaluronan synthases, a single polypeptide species, pmCS, possesses both transferase activities. |
GlyCosmos15-Glycan
| Id | Subject | Object | Predicate | Lexical cue | image |
|---|---|---|---|---|---|
| T1 | 42-53 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T2 | 318-329 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T3 | 578-589 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T4 | 884-890 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
| T5 | 908-919 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T6 | 1255-1266 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T7 | 1424-1435 | Glycan | denotes | chondroitin | https://api.glycosmos.org/wurcs2image/latest/png/binary/G43702JT |
| T8 | 1483-1489 | Glycan | denotes | GalNAc | https://api.glycosmos.org/wurcs2image/latest/png/binary/G39738WL |
GlyCosmos15-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 42-53 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 318-329 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 578-589 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 908-919 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T5 | 1255-1266 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T6 | 1424-1435 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 68-89 | OrganismTaxon | denotes | Pasteurella multocida | 747 |
| T2 | 98-119 | OrganismTaxon | denotes | Pasteurella multocida | 747 |
| T3 | 742-758 | OrganismTaxon | denotes | Escherichia coli | 562 |
GlyCosmos-GlycoEpitope
| Id | Subject | Object | Predicate | Lexical cue | glycoepitope_id |
|---|---|---|---|---|---|
| T1 | 42-53 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T2 | 318-329 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T3 | 578-589 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T4 | 908-919 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T5 | 1255-1266 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
| T6 | 1424-1435 | http://purl.jp/bio/12/glyco/glycan#Glycan_epitope | denotes | chondroitin | http://www.glycoepitope.jp/epitopes/EP0081 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 173-186 | Body_part | denotes | extracellular | http://purl.obolibrary.org/obo/GO_0005576 |