PubMed:10766914 / 423-812 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/10766914","sourcedb":"PubMed","sourceid":"10766914","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/10766914","text":"TR. 2. Addition of genistein (100 microM) to the intracellular solution caused a small decrease in single-channel current amplitude (i), but a large reduction in open probability (Po). 3. Single-channel analysis of channel block suggested that genistein (100 microM) may inhibit CFTR by two mechanisms: first, it may slow the rate of channel opening and second, it may block open channels.","tracks":[{"project":"2015-BEL-Sample","denotations":[{"id":"T1","span":{"begin":0,"end":389},"obj":"a(CHEBI:genistein) decreases p(MGI:Cftr)"}],"attributes":[{"subj":"T1","pred":"source","obj":"2015-BEL-Sample"}]},{"project":"2015-BEL-Sample-2","denotations":[{"id":"BEL:20000150","span":{"begin":0,"end":389},"obj":"a(CHEBI:genistein) decreases p(MGI:Cftr)"}],"attributes":[{"subj":"BEL:20000150","pred":"source","obj":"2015-BEL-Sample-2"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2015-BEL-Sample","color":"#93ecd1","default":true},{"id":"2015-BEL-Sample-2","color":"#ecb793"}]}]}}